Michael Berk

Summary

Affiliation: Barwon Health
Country: Australia

Publications

  1. ncbi request reprint The efficacy of adjunctive N-acetylcysteine in major depressive disorder: a double-blind, randomized, placebo-controlled trial
    Michael Berk
    Deakin University, PO Box 281, Geelong 3220, Australia
    J Clin Psychiatry 75:628-36. 2014
  2. pmc So depression is an inflammatory disease, but where does the inflammation come from?
    Michael Berk
    IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, Vic, Australia
    BMC Med 11:200. 2013
  3. pmc Molecular hydrogen: an overview of its neurobiological effects and therapeutic potential for bipolar disorder and schizophrenia
    Ahmad Ghanizadeh
    Research Center for Psychiatry and Behavioral Sciences, Shiraz University of Medical, Sciences, Hafez Hospital, Shiraz, Iran
    Med Gas Res 3:11. 2013
  4. pmc The association between diet quality, dietary patterns and depression in adults: a systematic review
    Shae E Quirk
    School of Medicine, Deakin University, Geelong, Australia
    BMC Psychiatry 13:175. 2013
  5. pmc A randomised, controlled trial of a dietary intervention for adults with major depression (the "SMILES" trial): study protocol
    Adrienne O'Neil
    IMPACT Strategic Research Centre, Deakin University, Deakin, Vic, Australia
    BMC Psychiatry 13:114. 2013
  6. pmc Gender differences in first episode psychotic mania
    Sue M Cotton
    Orygen Youth Health Research Centre, University of Melbourne, Locked Bag 10 35 Poplar Road, Parkville, Victoria, 3052, Australia
    BMC Psychiatry 13:82. 2013
  7. pmc A narrative review on the similarities and dissimilarities between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and sickness behavior
    Gerwyn Morris
    Tir Na Nog, Bryn Road Seaside 87, Llanelli SA152LW, UK
    BMC Med 11:64. 2013
  8. pmc Evaluation of the acceptability and usefulness of an information website for caregivers of people with bipolar disorder
    Lesley Berk
    IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, Victoria, Australia
    BMC Med 11:162. 2013
  9. pmc Physical comorbidities in men with mood and anxiety disorders: a population-based study
    Livia Sanna
    Unit of Psychiatry, Neurosciences, Mental Health and Sensory Organs Department NeSMOS, Faculty of Medicine and Psychology, Sant Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035 1037 00189 Rome, Italy
    BMC Med 11:110. 2013
  10. pmc Co-prescription of medication for bipolar disorder and diabetes mellitus: a nationwide population-based study with focus on gender differences
    Gjertrud Svendal
    Department of Clinical Medicine, Section for Psychiatry, University of Bergen, Sandviken Hospital, Sandviksleitet 1, N 5035 Bergen, Norway
    BMC Med 10:148. 2012

Collaborators

Detail Information

Publications129 found, 100 shown here

  1. ncbi request reprint The efficacy of adjunctive N-acetylcysteine in major depressive disorder: a double-blind, randomized, placebo-controlled trial
    Michael Berk
    Deakin University, PO Box 281, Geelong 3220, Australia
    J Clin Psychiatry 75:628-36. 2014
    ..N-acetylcysteine (NAC) is a redox-active glutathione precursor that decreases inflammatory cytokines, modulates glutamate, promotes neurogenesis, and decreases apoptosis, all of which contribute to the neurobiology of depression...
  2. pmc So depression is an inflammatory disease, but where does the inflammation come from?
    Michael Berk
    IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, Vic, Australia
    BMC Med 11:200. 2013
    ..It is similarly accompanied by increased oxidative and nitrosative stress (O&NS), which contribute to neuroprogression in the disorder. The obvious question this poses is 'what is the source of this chronic low-grade inflammation?'..
  3. pmc Molecular hydrogen: an overview of its neurobiological effects and therapeutic potential for bipolar disorder and schizophrenia
    Ahmad Ghanizadeh
    Research Center for Psychiatry and Behavioral Sciences, Shiraz University of Medical, Sciences, Hafez Hospital, Shiraz, Iran
    Med Gas Res 3:11. 2013
    ....
  4. pmc The association between diet quality, dietary patterns and depression in adults: a systematic review
    Shae E Quirk
    School of Medicine, Deakin University, Geelong, Australia
    BMC Psychiatry 13:175. 2013
    ..We performed a systematic review to evaluate existing evidence regarding the association between diet quality and depression...
  5. pmc A randomised, controlled trial of a dietary intervention for adults with major depression (the "SMILES" trial): study protocol
    Adrienne O'Neil
    IMPACT Strategic Research Centre, Deakin University, Deakin, Vic, Australia
    BMC Psychiatry 13:114. 2013
    ..Using a randomised controlled trial design, we aim to investigate the efficacy and cost-efficacy of a dietary program for the treatment of Major Depressive Episodes (MDE)...
  6. pmc Gender differences in first episode psychotic mania
    Sue M Cotton
    Orygen Youth Health Research Centre, University of Melbourne, Locked Bag 10 35 Poplar Road, Parkville, Victoria, 3052, Australia
    BMC Psychiatry 13:82. 2013
    ..The aim of this paper was to delineate the impact of gender on premorbid history, onset, and 18 month outcomes of first episode psychotic mania (FEPM) patients...
  7. pmc A narrative review on the similarities and dissimilarities between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and sickness behavior
    Gerwyn Morris
    Tir Na Nog, Bryn Road Seaside 87, Llanelli SA152LW, UK
    BMC Med 11:64. 2013
    ..It is concluded that sickness behavior and ME/CFS are two different conditions. ..
  8. pmc Evaluation of the acceptability and usefulness of an information website for caregivers of people with bipolar disorder
    Lesley Berk
    IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, Victoria, Australia
    BMC Med 11:162. 2013
    ..This paper reports on an evaluation of the acceptability and usefulness of the online version of the guidelines, http://www.bipolarcaregivers.org...
  9. pmc Physical comorbidities in men with mood and anxiety disorders: a population-based study
    Livia Sanna
    Unit of Psychiatry, Neurosciences, Mental Health and Sensory Organs Department NeSMOS, Faculty of Medicine and Psychology, Sant Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035 1037 00189 Rome, Italy
    BMC Med 11:110. 2013
    ....
  10. pmc Co-prescription of medication for bipolar disorder and diabetes mellitus: a nationwide population-based study with focus on gender differences
    Gjertrud Svendal
    Department of Clinical Medicine, Section for Psychiatry, University of Bergen, Sandviken Hospital, Sandviksleitet 1, N 5035 Bergen, Norway
    BMC Med 10:148. 2012
    ..It is unclear if this correlation is a part of common pathophysiological pathways, or if medication for bipolar disorder has negative effects on blood sugar regulation...
  11. pmc Moving towards a population health approach to the primary prevention of common mental disorders
    Felice N Jacka
    Deakin University, School of Medicine and Barwon Health, PO Box 281, Geelong 3220, Australia
    BMC Med 10:149. 2012
    ....
  12. pmc Is diagnosis enough to guide interventions in mental health? Using case formulation in clinical practice
    Craig A Macneil
    Early Psychosis Prevention and Intervention Centre EPPIC, and Orygen Youth Health Research Centre, ORYGEN Youth Health, 35 Poplar Road, Parkville, Melbourne, Victoria, 3052, Australia
    BMC Med 10:111. 2012
    ....
  13. pmc Cigarette smoking, nicotine dependence and anxiety disorders: a systematic review of population-based, epidemiological studies
    Steven Moylan
    Deakin University School of Medicine, Barwon Health, Geelong, Victoria, Australia
    BMC Med 10:123. 2012
    ....
  14. pmc Using lithium as a neuroprotective agent in patients with cancer
    Mustafa Khasraw
    Andrew Love Cancer Centre, Geelong Hospital, Victoria, Australia
    BMC Med 10:131. 2012
    ..This review discusses neurocognitive impairment in patients with cancer and the potential for investigating the use of lithium as a neuroprotectant in such patients...
  15. pmc Tobacco smoking predicts depression and poorer quality of life in heart disease
    Lesley Stafford
    Centre for Women s Mental Health, Royal Women s Hospital, Parkville, Australia
    BMC Cardiovasc Disord 13:35. 2013
    ..We report on the prospective association between smoking and depression and health-related quality of life (HRQOL) in patients with coronary artery disease (CAD)...
  16. pmc Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness
    Michael Berk
    School of Medicine, Deakin University, 75 Pigdon s Road, Waurn Ponds, Geelong, Victoria 3216, Australia
    BMC Med 11:74. 2013
    ....
  17. pmc The DSM-5: Hyperbole, Hope or Hypothesis?
    Michael Berk
    School of Medicine, Deakin University, Barwon Health, Ryrie Street, Geelong, VIC 3220, Australia
    BMC Med 11:128. 2013
    ....
  18. pmc The effects of apoptosis vulnerability markers on the myocardium in depression after myocardial infarction
    Yiming Wang
    Department of Psychiatry, Hospital Affiliated to Guiyang Medical University, 28 Guiyi Street, Guiyang City, 550004, Guizhou, China
    BMC Med 11:32. 2013
    ..This study aimed to attempt to confirm the effects of apoptosis vulnerability markers on the myocardium in a model of depression after myocardial infarction...
  19. doi request reprint The promise of N-acetylcysteine in neuropsychiatry
    Michael Berk
    School of Medicine, Deakin University, Geelong, Victoria, Australia
    Trends Pharmacol Sci 34:167-77. 2013
    ..Its benign tolerability profile, its action on multiple operative pathways, and the emergence of positive trial data make it an important target to investigate...
  20. ncbi request reprint The sick role, illness cognitions and outcomes in bipolar disorder
    Michael Berk
    School of Medicine, Deakin University, Geelong, VIC 3220, Australia
    J Affect Disord 146:146-9. 2013
    ..We conducted analyses to test the hypothesis that there may be an association between illness cognitions and clinical and functional measures...
  21. pmc Pathways to new drug discovery in neuropsychiatry
    Michael Berk
    Deakin University, School of Medicine, Barwon Health, P, O, Box 291, Geelong, 3220, Australia
    BMC Med 10:151. 2012
    ..Fruitful paradigms will require a break from the orthodoxy, and creativity and risk may well be the fingerprints of success.See related article http://www.biomedcentral.com/1741-7015/10/150...
  22. doi request reprint Palliative models of care for later stages of mental disorder: maximizing recovery, maintaining hope, and building morale
    Michael Berk
    School of Medicine, Deakin University, Geelong, Vic, Australia
    Aust N Z J Psychiatry 46:92-9. 2012
    ..In this paper, we argue the need to adopt 'palliative' models of care for some individuals, and consider changing the therapeutic goals to follow care pathways similar to those used in other chronic and refractory medical illnesses...
  23. doi request reprint Preventive strategies in depression: gathering evidence for risk factors and potential interventions
    Michael Berk
    Deakin University, P O Box 281, Geelong 3220, Australia
    Br J Psychiatry 201:339-41. 2012
    ....
  24. pmc Maintenance N-acetyl cysteine treatment for bipolar disorder: a double-blind randomized placebo controlled trial
    Michael Berk
    Deakin University, School of Medicine, Barwon Health, P O Box 291, Geelong, 3220, Australia
    BMC Med 10:91. 2012
    ..The current study aimed to investigate the maintenance effects of NAC following eight weeks of open-label treatment for bipolar disorder...
  25. pmc Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
    Michael Maes
    Maes Clinics TRIA, Piyavate Hospital, 998 Rimklongsamsen Road, Bangkok 10310, Thailand
    BMC Med 10:66. 2012
    ....
  26. doi request reprint Psychometric properties of a scale to measure investment in the sick role: the Illness Cognitions Scale
    Michael Berk
    Department of Clinical and Biomedical Sciences Barwon Health, University of Melbourne, Geelong, Victoria, Australia
    J Eval Clin Pract 18:360-4. 2012
    ..We describe the psychometric properties of a new scale, the Illness Cognitions Scale (ICS), a metric of investment in the sick role...
  27. pmc Prevalence of mood and anxiety disorder in self reported irritable bowel syndrome (IBS). An epidemiological population based study of women
    Arnstein Mykletun
    Norwegian Institute of Public Health, Division of Mental Heath, Oslo, Norway
    BMC Gastroenterol 10:88. 2010
    ..The aim of this study was therefore to re-examine the hypothesis using population-based data and psychiatric morbidity established with a structured clinical interview...
  28. doi request reprint Evidence and implications for early intervention in bipolar disorder
    Michael Berk
    Department of Clinical and Biomedical Sciences, University of Melbourne, Parkville, Australia
    J Ment Health 19:113-26. 2010
    ..To review the evidence that supports early intervention in the treatment of bipolar disorder...
  29. ncbi request reprint Sleep and depression - theory and practice
    Michael Berk
    Melbourne University, Barwon Health and The Geelong Clinic, Mental Health Research Institute, and ORYGEN Research Centre, Victoria
    Aust Fam Physician 38:302-4. 2009
    ..Sleep disorders are particularly common in the primary care setting, and are intimately interlinked with depression...
  30. doi request reprint Is this D vitamin to worry about? Vitamin D insufficiency in an inpatient sample
    Michael Berk
    Department of Clinical and Biomedical Sciences Barwon Health, University of Melbourne, Geelong, Australia
    Aust N Z J Psychiatry 42:874-8. 2008
    ..The aim of the present study was to investigate the relationship between reduced serum vitamin D levels and psychiatric illness...
  31. ncbi request reprint Do we need to flick the switch? The need for a broader conceptualization of iatrogenic course aggravation in clinical trials of bipolar disorder
    Michael Berk
    Department of Clinical and Biomedical Sciences, Barwon Health, University of Melbourne, Swanston Centre, VIC 3220, Australia
    Psychiatry Clin Neurosci 64:367-71. 2010
    ..This approach has the potential to capture a broader, more fine-grained and clinically relevant picture of the process of aggravation of the bipolar cycle...
  32. doi request reprint Glutamate cysteine ligase (GCL) and self reported depression: an association study from the HUNT
    Michael Berk
    School of Medicine, Deakin University, Geelong, Australia
    J Affect Disord 131:207-13. 2011
    ..The aim of the study was to investigate candidate polymorphisms of GCL validated in schizophrenia and their association with current state depression, as measured by the Hospital Anxiety and Depression Scale (HADS)...
  33. doi request reprint Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors
    M Berk
    Department of Clinical and Biomedical Sciences, University of Melbourne, Victoria 3010, Australia
    Neurosci Biobehav Rev 35:804-17. 2011
    ..Additionally, these pathways provide a cogent explanation for the efficacy of seemingly diverse therapies used in BD, that appear to share common effects on oxidative, inflammatory and neurotrophic pathways...
  34. doi request reprint The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: an open label trial
    Michael Berk
    Department of Psychiatry, The University of Melbourne, Parkville, Australia
    J Affect Disord 135:389-94. 2011
    ..Given the failure of almost all modern trials of antidepressants in bipolar disorder to demonstrate efficacy, and the limited efficacy of mood stabilisers in the depressive phase of the disorder, this is a major unmet need...
  35. ncbi request reprint From neuroprogression to neuroprotection: implications for clinical care
    Michael Berk
    Department of Clinical and Biomedical Sciences Barwon Health, University of Melbourne, Melbourne, Vic
    Med J Aust 193:S36-40. 2010
    ..These developments need to be combined with service initiatives to maximise the opportunities for early diagnosis and intervention...
  36. ncbi request reprint Qualitative methods in early-phase drug trials: broadening the scope of data and methods from an RCT of N-acetylcysteine in schizophrenia
    Michael Berk
    Department of Clinical and Biomedical Sciences Barwon Health, University of Melbourne, PO Box 281, Geelong 3220, Victoria, Australia
    J Clin Psychiatry 72:909-13. 2011
    ..To our knowledge, this mixed methodology has not previously been applied to blinded psychopharmacologic trials...
  37. doi request reprint Does stage of illness impact treatment response in bipolar disorder? Empirical treatment data and their implication for the staging model and early intervention
    Michael Berk
    School of Medicine, Deakin University, Geelong, Victoria 3220, Australia
    Bipolar Disord 13:87-98. 2011
    ..The staging model suggests that early stages of bipolar disorder respond better to treatments and have a more favourable prognosis. This study aims to provide empirical support for the model, and the allied construct of early intervention...
  38. ncbi request reprint Nail-biting stuff? The effect of N-acetyl cysteine on nail-biting
    Michael Berk
    Department of Clinical and Biomedical Sciences, University of Melbourne, Australia
    CNS Spectr 14:357-60. 2009
    ..Its actions, if robustly replicated, also point to potential treatment targets in glutathione or glutamate pathways in the brain...
  39. doi request reprint Glutathione: a novel treatment target in psychiatry
    Michael Berk
    Department of Clinical and Biomedical Sciences, Barwon Health, University of Melbourne, Geelong, Victoria, Australia
    Trends Pharmacol Sci 29:346-51. 2008
    ..This article outlines the multidimensional evidence that currently exists for oxidative stress mechanisms in psychiatric disorders and specifically discusses glutathione as a promising novel therapeutic target...
  40. ncbi request reprint The evolution of clinical audit as a tool for quality improvement
    Michael Berk
    Community and Mental Health Programme, Barwon Health, Geelong, Victoria, Australia
    J Eval Clin Pract 9:251-7. 2003
    ..A number of evolutionary changes in the audit process have improved the efficiency and effectiveness of the audit...
  41. ncbi request reprint Recent developments in the treatment of bipolar disorders
    Michael Berk
    Clinical and Biomedical Sciences, University of Melbourne, Community and Mental Health, Barwon Health, Swanton Centre, PO Box 281, Geelong, Victoria 3220, Australia
    Expert Opin Investig Drugs 12:1621-32. 2003
    ..A growing range of novel therapeutic options for the treatment of bipolar disorder is under investigation. This paper summarises some of the data regarding these potential therapeutic options...
  42. ncbi request reprint Mood stabilizers and treatment adherence in bipolar disorder: addressing adverse events
    Michael Berk
    Barwon Health and Geelong Clinic, University of Melbourne, Geelong, Victoria, Australia
    Ann Clin Psychiatry 15:217-24. 2003
    ..Guidelines for reducing and limiting adverse events are highlighted, as are recommendations for improving compliance associated with the experience of adverse events in the bipolar disorder population...
  43. ncbi request reprint Bipolar II disorder: a review
    Michael Berk
    Department of Clinical and Biomedical Sciences, University of Melbourne, Swanston Centre, Geelong, Victoria, Australia
    Bipolar Disord 7:11-21. 2005
    ..To review the current knowledge of bipolar II disorder...
  44. ncbi request reprint 'Bipolar missed states': the diagnosis and clinical salience of bipolar mixed states
    Michael Berk
    Barwon Health and The Geewong Clinic, Swanston Centre, PO Box 281, Geelong, Victoria 3220, Australia
    Aust N Z J Psychiatry 39:215-21. 2005
    ..To explore diagnostic and treatment issues concerning bipolar mixed states...
  45. ncbi request reprint The management of bipolar disorder in primary care: a review of existing and emerging therapies
    Michael Berk
    Department of Clinical and Biomedical Sciences, Barwon Health, University of Melbourne, Geelong, Victoria, Australia
    Psychiatry Clin Neurosci 59:229-39. 2005
    ..This paper will attempt to review existing and emerging therapies in bipolar disorder, as well as their common drug interactions and side-effects...
  46. ncbi request reprint Australasian commentary on CANMAT guidelines for treatment of bipolar disorder
    Michael Berk
    Department of Clinical and Biomedical Sciences, University of Melbourne, Swanston Centre, Geelong, Victoria, Australia
    Bipolar Disord 7:83-6. 2005
  47. ncbi request reprint The potential utility of a staging model as a course specifier: a bipolar disorder perspective
    Michael Berk
    Barwon Health and The Geelong Clinic, Geelong
    J Affect Disord 100:279-81. 2007
    ..A staging model compliments existing and proposed classifications of bipolar disorder, adding a temporal dimension to a cross sectional view. It may inform treatment choice and prognosis, and could have utility as a course specifier...
  48. ncbi request reprint Vitamin D deficiency may play a role in depression
    Michael Berk
    The University of Melbourne, Department of Clinical and Biomedical Sciences, PO Box 281, Geelong 3220, Victoria, Australia
    Med Hypotheses 69:1316-9. 2007
    ..There are a number of trials that have suggested a role for Vitamin D in the supplementary treatment of depression. Dose may be a critical issue, as sun exposure and dietary intake may be low and high doses may be required...
  49. ncbi request reprint The Bipolar Depression Rating Scale (BDRS): its development, validation and utility
    Michael Berk
    Barwon Health and The Geelong Clinic, Geelong Department of Clinical and Biomedical Sciences, University of Melbourne and ORYGEN Research Centre, Melbourne, Victoria, Australia
    Bipolar Disord 9:571-9. 2007
    ..Both clinically and in research there is a growing need for a new observer-rated scale that is specifically designed to assess bipolar depression...
  50. ncbi request reprint Efficacy of atypical antipsychotics in bipolar disorder
    Michael Berk
    Department of Clinical and Biomedical Sciences, The University of Melbourne, Swanston Centre, PO Box 281, Geelong, VIC 3220, Australia
    Drugs 65:257-69. 2005
    ..A number of trials are underway that will hopefully address many of the questions still pending...
  51. ncbi request reprint Setting the stage: from prodrome to treatment resistance in bipolar disorder
    Michael Berk
    Barwon Health and The Geelong Clinic, Geelong, Victoria, Australia
    Bipolar Disord 9:671-8. 2007
    ..At the other end of the spectrum, the model attempts to operationalize treatment resistance. The utility of the model will need to be validated by empirical research...
  52. ncbi request reprint Early intervention in bipolar disorders: opportunities and pitfalls
    Michael Berk
    Barwon Health, University of Melbourne, Geelong, Vic, Australia
    Med J Aust 187:S11-4. 2007
    ..There is a need for early identification, and to develop treatments and services applicable to the specific needs of this population...
  53. ncbi request reprint Emerging options in the treatment of bipolar disorders
    M Berk
    Department of Psychiatry, University of Melbourne, Geelong, Victoria, Australia
    Drugs 61:1407-14. 2001
    ..Data regarding the atypical agents in other phases of the illness are awaited. The options available for this difficult to treat condition is increasing with the new range of agents...
  54. pmc Treatment and outcomes of an Australian cohort of outpatients with bipolar I or schizoaffective disorder over twenty-four months: implications for clinical practice
    Jayashri Kulkarni
    Monash Alfred Psychiatry Research Centre, The Alfred Hospital and Monash University, Central Clinical School, 607 St Kilda Rd, Melbourne, Vic, 3004, Australia
    BMC Psychiatry 12:228. 2012
    ..All participants received treatment as usual. There was no study medication...
  55. doi request reprint Lifetime psychiatric disorders and body composition: a population-based study
    Lana J Williams
    Department of Clinical and Biomedical Sciences Barwon Health, The University of Melbourne, PO Box 281, Geelong 3220, Australia
    J Affect Disord 118:173-9. 2009
    ..This study aimed to investigate the relationship between depressive and anxiety disorders and indices of adiposity, including body fat mass and percent body fat, as measured by dual energy X-ray absorptiometry...
  56. doi request reprint Association of Western and traditional diets with depression and anxiety in women
    Felice N Jacka
    Department of Clinical and Biomedical Sciences, University of Melbourne, Geelong 3220, Australia
    Am J Psychiatry 167:305-11. 2010
    ..This study examined the extent to which the high-prevalence mental disorders are related to habitual diet in 1,046 women ages 20-93 years randomly selected from the population...
  57. doi request reprint A prospective study of the impact of smoking on outcomes in bipolar and schizoaffective disorder
    Seetal Dodd
    Department of Clinical and Biomedical Sciences, Barwon Health, The University of Melbourne, PO Box 281, Geelong VIC 3220, Australia
    Compr Psychiatry 51:504-9. 2010
    ..The impact of tobacco smoking on mental health outcomes was investigated in a 24-month, naturalistic, longitudinal study of 240 people with bipolar disorder or schizoaffective disorder...
  58. doi request reprint Going up in smoke: tobacco smoking is associated with worse treatment outcomes in mania
    Michael Berk
    University of Melbourne, Victoria, Australia
    J Affect Disord 110:126-34. 2008
    ..This study aimed to compare the treatment responses between smokers and non-smokers in bipolar mania clinical trials...
  59. ncbi request reprint Monitoring the safe use of clozapine: a consensus view from Victoria, Australia
    Michael Berk
    Department of Clinical and Biomedical Sciences, Barwon Health, The University of Melbourne, Geelong, Melbourne, Victoria, Australia
    CNS Drugs 21:117-27. 2007
    ....
  60. doi request reprint Habitual physical activity and the risk for depressive and anxiety disorders among older men and women
    Julie A Pasco
    Department of Clinical and Biomedical Sciences, Barwon Health, The University of Melbourne, Geelong, Australia
    Int Psychogeriatr 23:292-8. 2011
    ..We investigated habitual physical activity as a risk factor for de novo depressive and anxiety disorders in older men and women from the general population...
  61. doi request reprint Putative neuroprotective agents in neuropsychiatric disorders
    Seetal Dodd
    School of Medicine, Deakin University, Geelong, Victoria, Australia Department of Psychiatry, University of Melbourne, Parkville, Victoria, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 42:135-45. 2013
    ..These agents are putative neuroprotective agents for schizophrenia and mood disorders...
  62. doi request reprint Annual high-dose vitamin D3 and mental well-being: randomised controlled trial
    Kerrie M Sanders
    Department of Clinical and Biomedical Sciences, Barwon Health, PO Box 281, Geelong, Victoria, Australia 3220
    Br J Psychiatry 198:357-64. 2011
    ..Epidemiological evidence supports a relationship between vitamin D and mental well-being, although evidence from large-scale placebo-controlled intervention trials is lacking...
  63. doi request reprint Obesity and the relationship with positive and negative affect
    Julie A Pasco
    School of Medicine, Deakin University, Geelong, VIC 3220, Australia
    Aust N Z J Psychiatry 47:477-82. 2013
    ..To examine the cross-sectional association between overweight and obesity and positive and negative affect...
  64. doi request reprint Effects of N-acetyl cysteine on cognitive function in bipolar disorder
    Olivia M Dean
    School of Medicine, Deakin University, Melbourne, Australia
    Psychiatry Clin Neurosci 66:514-7. 2012
    ..Adjunctive treatment with NAC improves the symptoms experienced by those with bipolar disorder, particularly depression, and it was hypothesized that cognition may also be improved following NAC treatment...
  65. doi request reprint Dietary selenium and major depression: a nested case-control study
    Julie A Pasco
    School of Medicine, Deakin University, Geelong, Victoria 3220, Australia
    Complement Ther Med 20:119-23. 2012
    ..Dietary selenium intake was measured using a food frequency questionnaire at baseline, together with anthropometric and lifestyle measures...
  66. ncbi request reprint Are illness perceptions about coronary artery disease predictive of depression and quality of life outcomes?
    Lesley Stafford
    Department of Psychology, University of Melbourne, Melbourne, Australia
    J Psychosom Res 66:211-20. 2009
    ..We also examined the association between these beliefs and health-related quality of life (HRQOL) and socio-demographic variations in illness beliefs...
  67. doi request reprint Effects of N-acetyl-cysteine treatment on glutathione depletion and a short-term spatial memory deficit in 2-cyclohexene-1-one-treated rats
    Kwok Ho Christopher Choy
    Mental Health Research Institute, Parkville, Victoria, Australia
    Eur J Pharmacol 649:224-8. 2010
    ..These effects appear to be dose-dependent and region-specific. These results may be relevant to the understanding and management of the cognitive symptoms of schizophrenia and bipolar disorder...
  68. ncbi request reprint Leptin in depressed women: cross-sectional and longitudinal data from an epidemiologic study
    Julie A Pasco
    Department of Clinical and Biomedical Sciences Barwon Health, The University of Melbourne, Geelong 3220, Australia
    J Affect Disord 107:221-5. 2008
    ..In this study we aimed to investigate the relationship between serum leptin level and depression in a community sample of women using both cross-sectional and longitudinal data...
  69. ncbi request reprint N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial
    Michael Berk
    The Mental Health Research Institute of Victoria, Victoria, Australia
    Biol Psychiatry 64:468-75. 2008
    ..We hypothesized that treatment with N-acetyl cysteine (NAC), a safe, orally bioavailable precursor of glutathione, may improve the depressive component of bipolar disorder...
  70. doi request reprint Socioeconomic status and quality of life in population-based Australian men: data from the Geelong Osteoporosis Study
    Sharon L Brennan
    NorthWest Academic Centre, Department of Medicine, Sunshine Hospital, The University of Melbourne, Victoria
    Aust N Z J Public Health 37:226-32. 2013
    ..5, 95%CI 0.4-0.7, p<0.001). These relationships were similar for IEO and IER. CONCLUSIONS : Men from lower and upper SES groups have lower QOL compared to their counterparts in the mid SES group...
  71. doi request reprint Quantitative Heel Ultrasound (QUS) measures of bone quality in association with mood and anxiety disorders
    Lana J Williams
    School of Medicine, Deakin University, Geelong, Australia
    J Affect Disord 146:395-400. 2013
    ..Thus, we investigated the association between QUS parameters, mood and anxiety disorders in a population-based sample of 745 men and 897 women...
  72. doi request reprint The prevalence of mood and anxiety disorders in Australian women
    Lana Williams
    Department of Clinical and Biomedical Sciences, Barwon Health, The University of Melbourne, Geelong, Vic, Australia
    Australas Psychiatry 18:250-5. 2010
    ..We aimed to report the prevalence, age-of-onset and comorbidity of mood and anxiety disorders in an age-stratified representative sample of Australian women aged 20 years and over...
  73. doi request reprint Depression and bone metabolism. A review
    Lana J Williams
    Department of Clinical and Biomedical Sciences Barwon Health, University of Melbourne, Geelong, VIC Australia
    Psychother Psychosom 78:16-25. 2009
    ..This paper aims to review the current evidence on the relationship between depression and bone mineral density, and identify potential mechanisms...
  74. doi request reprint The association between depressive and anxiety symptoms and bone mineral density in the general population: the HUNT Study
    Lana J Williams
    University of Melbourne, Department of Clinical and Biomedical Sciences Barwon Health, Geelong, Australia
    J Affect Disord 131:164-71. 2011
    ..Longitudinal evidence is limited and this is yet to be examined among community-dwelling adults with anxiety. We aimed to investigate the cross-sectional and longitudinal relationships between anxiety and depressive symptoms and BMD...
  75. doi request reprint N-acetyl cysteine restores brain glutathione loss in combined 2-cyclohexene-1-one and d-amphetamine-treated rats: relevance to schizophrenia and bipolar disorder
    Olivia M Dean
    The Mental Health Research Institute of Victoria, Parkville, Victoria, Australia
    Neurosci Lett 499:149-53. 2011
    ..While NAC was shown to be beneficial in this model, the lack of additional glutathione depletion by amphetamine in combination with CHX does not support a summative interaction between oxidative stress and altered dopamine transmission...
  76. doi request reprint Illness beliefs about heart disease and adherence to secondary prevention regimens
    Lesley Stafford
    Department of Psychology, School of Behavioural Science, University of Melbourne, Australia
    Psychosom Med 70:942-8. 2008
    ..Causal attributions of CAD and their concordance with actual patient risk profiles were also examined...
  77. doi request reprint A preliminary evaluation of the validity of at-risk criteria for bipolar disorders in help-seeking adolescents and young adults
    Andreas Bechdolf
    ORYGEN Youth Health, Department of Youth Mental Health, University of Melbourne, Australia
    J Affect Disord 127:316-20. 2010
    ..In the current study, the predictive validity of these criteria were tested in help-seeking adolescents and young adults...
  78. ncbi request reprint The empirical redefinition of the psychometric criteria for remission in bipolar disorder
    Michael Berk
    Barwon Health and The Geelong Clinic, Geelong, Victoria, Australia
    J Affect Disord 106:153-8. 2008
    ....
  79. doi request reprint Reliability of the Mood Disorder Questionnaire: comparison with the Structured Clinical Interview for the DSM-IV-TR in a population sample
    Seetal Dodd
    University of Melbourne, Department of Clinical and Biomedical Sciences, Barwon Health, Geelong, Vic, Australia
    Aust N Z J Psychiatry 43:526-30. 2009
    ..The aim of the present study was therefore to investigate the reliability of this instrument...
  80. doi request reprint Tobacco smoking as a risk factor for major depressive disorder: population-based study
    Julie A Pasco
    Department of Clinical and Biomedical Sciences Barwon Health, The University of Melbourne, PO Box 281, Geelong 3220, Australia
    Br J Psychiatry 193:322-6. 2008
    ..Smoking is disproportionately prevalent among people with psychiatric illness...
  81. doi request reprint Association of high-sensitivity C-reactive protein with de novo major depression
    Julie A Pasco
    Epidemiology and Biostatistics Unit, Department of Clinical and Biomedical Sciences, Barwon Health, The University of Melbourne, PO Box 281, Geelong 3220, Australia
    Br J Psychiatry 197:372-7. 2010
    ..Although there is cross-sectional evidence that changes in the immune system contribute to the pathophysiology of depression, longitudinal data capable of elucidating cause and effect relationships are lacking...
  82. pmc The impact of statins on psychological wellbeing: a systematic review and meta-analysis
    Adrienne O'Neil
    School of Medicine, Deakin University, Geelong, Victoria, Australia
    BMC Med 10:154. 2012
    ..We aimed to conduct a meta-analysis to determine the impact of statins on psychological wellbeing of individuals with or without hypercholesterolemia...
  83. doi request reprint The association between habitual diet quality and the common mental disorders in community-dwelling adults: the Hordaland Health study
    Felice N Jacka
    Department of Clinical and Biomedical Sciences, The University of Melbourne, Barwon Health, Geelong, Australia
    Psychosom Med 73:483-90. 2011
    ..Recent evidence suggests a role for diet quality in the common mental disorders depression and anxiety. We aimed to investigate the association between diet quality, dietary patterns, and the common mental disorders in Norwegian adults...
  84. doi request reprint A descriptive interview with 64 patients discharged from an acute-psychiatric-inpatient service
    Tom Callaly
    Community and Mental Health, Barwon Health, Swanston Centre, Geelong, Victoria, Australia
    J Eval Clin Pract 14:990-5. 2008
    ..This study compares the findings of comprehensive interviews conducted with current and past patients of the community mental-health service 3 or more years following case closure from the community ambulatory service...
  85. doi request reprint Diet quality in bipolar disorder in a population-based sample of women
    Felice N Jacka
    The University of Melbourne, Department of Clinical and Biomedical Sciences Barwon Health, Geelong, Australia
    J Affect Disord 129:332-7. 2011
    ..This study examined the association between diet quality and bipolar disorder (BD) in an epidemiological cohort of randomly selected, population-based women aged 20-93 years...
  86. doi request reprint N-acetyl cysteine as a glutathione precursor for schizophrenia--a double-blind, randomized, placebo-controlled trial
    Michael Berk
    The Mental Health Research Institute of Victoria, Parkville, Australia
    Biol Psychiatry 64:361-8. 2008
    ..This study was conducted to evaluate the safety and effectiveness of oral NAC (1 g orally twice daily [b.i.d.]) as an add-on to maintenance medication for the treatment of chronic schizophrenia over a 24-week period...
  87. doi request reprint Area-based socioeconomic status and mood disorders: cross-sectional evidence from a cohort of randomly selected adult women
    Lana J Williams
    School of Medicine, Deakin University, Geelong, Australia
    Maturitas 69:173-8. 2011
    ..The aim of this study was to investigate the association between mood disorders and area-based socio-economic status (SES), and whether both ends of the SES continuum experienced increased odds for a mood disorder...
  88. doi request reprint Selective serotonin reuptake inhibitor use and bone mineral density in women with a history of depression
    Lana J Williams
    Department of Clinical and Biomedical Sciences, Barwon Health, The University of Melbourne, Geelong, Victoria, Australia
    Int Clin Psychopharmacol 23:84-7. 2008
    ..03) than nonusers. No differences in BMD were detected at other sites. Although the mechanism remains unclear, these observations are consistent with a role for the serotonergic system in regulating bone metabolism...
  89. doi request reprint Cognitive-personality style as vulnerability to depression in patients with coronary artery disease: roles of sociotropy and autonomy
    Lesley Stafford
    Department of Psychology, School of Behavioural Science, University of Melbourne, Australia
    Psychosom Med 71:63-9. 2009
    ..Depression occurs commonly in patients with CAD and is associated with substantial disability...
  90. doi request reprint Patterns of alcohol use and associated physical and lifestyle characteristics according to new Australian guidelines
    Carolyn E Coulson
    University of Melbourne, Department of Clinical and Biomedical Sciences Barwon Health, PO Box 281, Geelong 3220, Victoria, Australia
    Aust N Z J Psychiatry 44:946-51. 2010
    ..To describe the pattern of alcohol consumption and associated physical and lifestyle characteristics in a population-based sample of Australian men...
  91. ncbi request reprint Self-reported depression and cardiovascular risk factors in a community sample of women
    Felice N Jacka
    University of Melbourne, Department of Clinical and Biomedical Sciences, Barwon Health, P O Box 281, Geelong 3220, Victoria, Australia
    Psychosomatics 48:54-9. 2007
    ..However, a history of smoking increased the odds of reporting an LHx, whereas women with self-reported angina were more than four times more likely to report an age-adjusted LHx...
  92. doi request reprint Enhancing medication adherence in patients with bipolar disorder
    Lesley Berk
    University of Melbourne, Victoria, Australia
    Hum Psychopharmacol 25:1-16. 2010
    ....
  93. doi request reprint Who's left? Symptoms of schizophrenia that predict clinical trial dropout
    Jason Thompson
    Department of Clinical and Biomedical Sciences Barwon Health, University of Melbourne, Melbourne, Victoria, Australia
    Hum Psychopharmacol 26:609-13. 2011
    ..These findings reflect important considerations for the future design of clinical trials involving people with schizophrenia and may also provide clues into treatment compliance issues more generally...
  94. ncbi request reprint Intervention in individuals at ultra-high risk for psychosis: a review and future directions
    Patrick D McGorry
    Centre for Youth Mental Health, Orygen Youth Health Research Centre, University of Melbourne, Victoria, Australia
    J Clin Psychiatry 70:1206-12. 2009
    ..This article reviews intervention research in the ultra-high-risk phase of psychotic disorders...
  95. doi request reprint The management of individuals with bipolar disorder: a review of the evidence and its integration into clinical practice
    Gin S Malhi
    CADE Clinic, Department of Psychiatry, Royal North Shore Hospital, Sydney, New South Wales, Australia
    Drugs 69:2063-101. 2009
    ..Therefore, this paper summarizes the efficacy data for treating bipolar disorder and also applies clinical considerations to these data when formulating recommendations for the management of bipolar disorder...
  96. ncbi request reprint Diagnosing bipolar disorder: how can we do it better?
    Michael Berk
    Department of Clinical and Biomedical Sciences, Barwon Health, University of Melbourne, Geelong, Vic, Australia
    Med J Aust 184:459-62. 2006
    ..There is a risk of over-diagnosis of bipolar disorder among patients who are histrionic, show abnormal illness behaviour and/or have issues of secondary gain...
  97. doi request reprint The validity of the CGI severity and improvement scales as measures of clinical effectiveness suitable for routine clinical use
    Michael Berk
    Department of Clinical and Biomedical Sciences, Barwon Health, University of Melbourne, Geelong, Victoria, Australia
    J Eval Clin Pract 14:979-83. 2008
    ..The Clinical Global Impression Scale (CGI) is established as a core metric in psychiatric research. This study aims to test the validity of CGI as a clinical outcome measure suitable for routine use in a private inpatient setting...
  98. doi request reprint The use of statins after a cardiac intervention is associated with reduced risk of subsequent depression: proof of concept for the inflammatory and oxidative hypotheses of depression?
    Lesley Stafford
    Centre for Women s Mental Health, Royal Women s Hospital, Parkville, Victoria, Australia
    J Clin Psychiatry 72:1229-35. 2011
    ..We prospectively investigated whether the use of statins was associated with a reduced risk of development of depression in individuals who have had a cardiac event or intervention...
  99. doi request reprint Readmission to an acute psychiatric unit within 28 days of discharge: identifying those at risk
    Thomas Callaly
    Mental Health, Drugs and Alcohol Services, Swanston Centre, Barwon Health, Geelong, VIC 3220, Australia
    Aust Health Rev 34:282-5. 2010
    ..To examine factors that could help identify those most at risk of readmission to an acute psychiatric in-patient unit within 28 days of a discharge...
  100. doi request reprint Early intervention in bipolar disorders: clinical, biochemical and neuroimaging imperatives
    Michael Berk
    Department of Clinical and Biomedical Sciences, University of Melbourne, PO Box 281, Geelong, Australia
    J Affect Disord 114:1-13. 2009
    ....
  101. doi request reprint Group-based psychosocial intervention for bipolar disorder: randomised controlled trial
    David Castle
    Department of Psychiatry, University of Melbourne, and St Vincent s Health, Fitzroy 3065, Australia
    Br J Psychiatry 196:383-8. 2010
    ..Psychosocial interventions have the potential to enhance relapse prevention in bipolar disorder...