Research Topics
| Katherine A BarracloughSummaryCountry: Australia Publications
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Detail Information
Publications
A limited sampling strategy for the simultaneous estimation of tacrolimus, mycophenolic acid and unbound prednisolone exposure in adult kidney transplant recipientsKatherine A Barraclough
Department of Nephrology, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia
Nephrology (Carlton) 17:294-9. 2012..The aim of this study was to develop a limited sampling strategy (LSS) for the simultaneous estimation of exposure to tacrolimus, mycophenolic acid and unbound prednisolone in adult kidney transplant recipients...
The role of 25-hydroxyvitamin D deficiency in promoting insulin resistance and inflammation in patients with chronic kidney disease: a randomised controlled trialWilliam G Petchey
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
BMC Nephrol 10:41. 2009..Secondary hypotheses will test whether this is associated with decreased inflammation and bone/adipocyte-endocrine dysregulation...
Evaluation of limited sampling strategies for total and free prednisolone in adult kidney transplant recipientsKatherine A Barraclough
Department of Nephrology, University of Queensland at the Princess Alexandra Hospital, Level 2, ARTS Building, Ipswich Road, Woolloongabba, Brisbane 4102, QLD, Australia
Eur J Clin Pharmacol 67:1243-52. 2011....
Evaluation of limited sampling methods for estimation of tacrolimus exposure in adult kidney transplant recipientsKatherine A Barraclough
Department of Nephrology, University of Queensland at the Princess Alexandra Hospital, Brisbane, QLD 4102, Australia
Br J Clin Pharmacol 71:207-23. 2011..To examine the predictive performance of limited sampling methods for estimation of tacrolimus exposure in adult kidney transplant recipients...
Review: Pharmacodynamic monitoring of immunosuppression in kidney transplantationKatherine A Barraclough
Department of Renal Medicine, University of Queensland at the Princess Alexandra Hospital, Queensland, Australia
Nephrology (Carlton) 15:522-32. 2010..The purpose of this review is to provide the clinician with an overview of the methodology and use of immune function monitoring in the field of kidney transplantation...
Evaluation of the mycophenolic acid exposure estimation methods used in the APOMYGERE, FDCC, and Opticept trialsKatherine A Barraclough
Department of Renal Medicine, University of Queensland at the Princess Alexandra Hospital, Woolloongabba, Brisbane, Australia
Transplantation 90:44-51. 2010..Results were conflicting. This study aimed to compare the ability of these methodologies to predict AUC(0-12) in an independent cohort of kidney transplant recipients...
Pharmacogenetic influences on mycophenolate therapyKatherine A Barraclough
Department of Nephrology, Level 2, ARTS Building, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, QLD 4102, Australia
Pharmacogenomics 11:369-90. 2010..This article provides an extensive overview of the known effects of these SNPs on the pharmacokinetics and pharmacodynamics of MPA...
Hepatitis B virus infection in hemodialysis populations: progress toward preventionKatherine A Barraclough
Department of Nephrology, University of Queensland, Princess Alexandra Hospital, Brisbane, Australia
Kidney Int 77:177-80. 2010..However, its ability to improve overall seroconversion response remains unproven...
Prevention of access-related infection in dialysisKatherine A Barraclough
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Expert Rev Anti Infect Ther 7:1185-200. 2009....
Rationale and design of the oral HEMe iron polypeptide Against Treatment with Oral Controlled Release Iron Tablets trial for the correction of anaemia in peritoneal dialysis patients (HEMATOCRIT trial)Katherine A Barraclough
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
BMC Nephrol 10:20. 2009....
Intradermal versus intramuscular hepatitis B vaccination in hemodialysis patients: a prospective open-label randomized controlled trial in nonresponders to primary vaccinationKatherine A Barraclough
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Am J Kidney Dis 54:95-103. 2009..Primary hepatitis B virus (HBV) vaccination through the intramuscular (IM) route is less efficacious in dialysis patients than in the general population. Previous studies suggest improved seroconversion with intradermal (ID) vaccination...
Evaluation of limited sampling strategies for mycophenolic acid after mycophenolate mofetil intake in adult kidney transplant recipientsKatherine A Barraclough
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Ther Drug Monit 32:723-33. 2010..High variability in performance of LSSs highlights the importance of validating any LSS before applying it to an alternative population. Attention to comedication use is of particular relevance when choosing a LSS...
Kidney transplant outcomes are related to tacrolimus, mycophenolic acid and prednisolone exposure in the first weekKatherine A Barraclough
Department of Nephrology, University of Queensland at the Princess Alexandra Hospital, Brisbane, QLD, Australia
Transpl Int 25:1182-93. 2012..1, 284.4), P = 0.001]. This study highlights the importance of achieving early target exposure and suggests a potential role for individualized initial dosing or early therapeutic monitoring of all three immunosuppressive agents...
NR1I2 polymorphisms are related to tacrolimus dose-adjusted exposure and BK viremia in adult kidney transplantationKatherine A Barraclough
Department of Nephrology, University of Queensland at the Princess Alexandra Hospital, Brisbane, Australia
Transplantation 94:1025-32. 2012..Pregnane X, encoded by the gene NR112, is a nuclear receptor whose primary role is to promote the detoxification and clearance of drugs and other foreign compounds from the body...
Once- versus twice-daily tacrolimus: are the formulations truly equivalent?Katherine A Barraclough
Department of Nephrology, University of Queensland at the Princess Alexandra Hospital, Brisbane, QLD, Australia
Drugs 71:1561-77. 2011..This article reviews the pharmacokinetics, efficacy, adverse effects and utility of Advagraf® in relation to its equivalence to Prograf®, and areas that require additional research are identified...
A differential impact of mycophenolic acid, prednisolone, and tacrolimus exposure on sCD30 levels in adult kidney transplant recipientsKatherine A Barraclough
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Ther Drug Monit 35:240-5. 2013..However, there has been minimal study of the influence of individual immunosuppressive drugs on sCD30 levels...
Clinical pharmacokinetics and pharmacodynamics of prednisolone and prednisone in solid organ transplantationTroels K Bergmann
University of Queensland School of Pharmacy, Pharmacy Australia Centre of Excellence, 20 Cornwall St, Woolloongabba, Brisbane, QLD, 4102, Australia
Clin Pharmacokinet 51:711-41. 2012....
BK Virus in Kidney Transplant Recipients: The Influence of ImmunosuppressionKatherine A Barraclough
Department of Nephrology, University of Queensland at the Princess Alexandra Hospital, Brisbane, QLD 4102, Australia
J Transplant 2011:750836. 2011..Evidence supporting the various immunosuppression reduction strategies utilised in the management of BK virus will also be briefly discussed...
Renal graft rejection after allogeneic peripheral-blood stem cell transplantationKatherine A Barraclough
Department of Renal Medicine, Bone Marrow Transplant Program, Alfred Hospital, Melbourne, Australia
Am J Kidney Dis 48:822-6. 2006..We speculate that the engrafting third-party hematopoiesis produced acute renal allograft rejection with secondary microangiopathic hemolysis through a graft-versus-graft mechanism...
