Gavin Lambert

Summary

Affiliation: Baker Heart Research Institute
Country: Australia

Publications

  1. ncbi request reprint Effect of sunlight and season on serotonin turnover in the brain
    G W Lambert
    Human Neurotransmitter Laboratory and Alfred and Baker Medical Unit, Baker Heart Research Institute, PO Box 6492, St Kilda Road Central, Victoria 8008, Melbourne, Australia
    Lancet 360:1840-2. 2002
  2. ncbi request reprint Increased suicide rate in the middle-aged and its association with hours of sunlight
    Gavin Lambert
    Human Neurotransmitter Laboratory, Baker Medical Research Institute, Australia
    Am J Psychiatry 160:793-5. 2003
  3. ncbi request reprint Sympathetic activity in major depressive disorder: identifying those at increased cardiac risk?
    David A Barton
    Human Neurotransmitter Laboratory, Australia
    J Hypertens 25:2117-24. 2007
  4. ncbi request reprint Subarachnoid haemorrhage-induced sympathoexcitation in rats is reversed by bosentan or sodium nitroprusside
    G Lambert
    Laboratoire de Pharmacologie, CNRS UMR 8604, Faculte de Medecine Necker, Paris, France
    Clin Exp Pharmacol Physiol 28:200-5. 2001
  5. ncbi request reprint Monoamine metabolism and sympathetic nervous activation following subarachnoid haemorrhage: influence of gender and hydrocephalus
    Gavin Lambert
    Department of Clinical Physiology, Sahlgrenska University Hospital, Gothenbourg, Sweden
    Brain Res Bull 58:77-82. 2002
  6. pmc Acute response to intracisternal bupivacaine in patients with refractory pain of the head and neck
    Gavin Lambert
    Department of Clinical Physiology, Sahlgrenska Hospital, Goteborg, Sweden
    J Physiol 570:421-8. 2006
  7. ncbi request reprint Paring down on Descartes: a review of brain noradrenaline and sympathetic nervous function
    G W Lambert
    Human Neurotransmitter Laboratory, Baker Medical Research Institute, Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 28:979-82. 2001
  8. doi request reprint Human sympathetic nerve biology: parallel influences of stress and epigenetics in essential hypertension and panic disorder
    Murray Esler
    Baker Heart Research Institute, Melbourne, Australia
    Ann N Y Acad Sci 1148:338-48. 2008
  9. ncbi request reprint Increased brain serotonin turnover in panic disorder patients in the absence of a panic attack: reduction by a selective serotonin reuptake inhibitor
    Murray Esler
    Baker Heart Research Institute, Melbourne, Vic, Australia
    Stress 10:295-304. 2007
  10. ncbi request reprint Gender differences in sympathetic nervous activity: influence of body mass and blood pressure
    Elisabeth Lambert
    Human Neurotransmitters Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia
    J Hypertens 25:1411-9. 2007

Collaborators

Detail Information

Publications59

  1. ncbi request reprint Effect of sunlight and season on serotonin turnover in the brain
    G W Lambert
    Human Neurotransmitter Laboratory and Alfred and Baker Medical Unit, Baker Heart Research Institute, PO Box 6492, St Kilda Road Central, Victoria 8008, Melbourne, Australia
    Lancet 360:1840-2. 2002
    ..294, p=0.010), and rose rapidly with increased luminosity. Our findings are further evidence for the notion that changes in release of serotonin by the brain underlie mood seasonality and seasonal affective disorder...
  2. ncbi request reprint Increased suicide rate in the middle-aged and its association with hours of sunlight
    Gavin Lambert
    Human Neurotransmitter Laboratory, Baker Medical Research Institute, Australia
    Am J Psychiatry 160:793-5. 2003
    ....
  3. ncbi request reprint Sympathetic activity in major depressive disorder: identifying those at increased cardiac risk?
    David A Barton
    Human Neurotransmitter Laboratory, Australia
    J Hypertens 25:2117-24. 2007
    ..Evidence exists linking major depressive disorder (MDD) with clinical cardiovascular events. The importance of the sympathetic nervous system in the generation of cardiac risk in other contexts is established...
  4. ncbi request reprint Subarachnoid haemorrhage-induced sympathoexcitation in rats is reversed by bosentan or sodium nitroprusside
    G Lambert
    Laboratoire de Pharmacologie, CNRS UMR 8604, Faculte de Medecine Necker, Paris, France
    Clin Exp Pharmacol Physiol 28:200-5. 2001
    ..4. Our results indicate that subarachnoid haemorrhage is associated with an acute activation of the sympathetic nervous system. The degree of sympathoexcitation can be reversed by the use of either bosentan or SNP...
  5. ncbi request reprint Monoamine metabolism and sympathetic nervous activation following subarachnoid haemorrhage: influence of gender and hydrocephalus
    Gavin Lambert
    Department of Clinical Physiology, Sahlgrenska University Hospital, Gothenbourg, Sweden
    Brain Res Bull 58:77-82. 2002
    ..The diminished cerebral perfusion seen following subarachnoid bleeding may occur as a result of activation of central catecholaminergic neurones...
  6. pmc Acute response to intracisternal bupivacaine in patients with refractory pain of the head and neck
    Gavin Lambert
    Department of Clinical Physiology, Sahlgrenska Hospital, Goteborg, Sweden
    J Physiol 570:421-8. 2006
    ..Although these effects are transient, they warrant caution at the induction of intracisternal local anaesthesia...
  7. ncbi request reprint Paring down on Descartes: a review of brain noradrenaline and sympathetic nervous function
    G W Lambert
    Human Neurotransmitter Laboratory, Baker Medical Research Institute, Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 28:979-82. 2001
    ....
  8. doi request reprint Human sympathetic nerve biology: parallel influences of stress and epigenetics in essential hypertension and panic disorder
    Murray Esler
    Baker Heart Research Institute, Melbourne, Australia
    Ann N Y Acad Sci 1148:338-48. 2008
    ....
  9. ncbi request reprint Increased brain serotonin turnover in panic disorder patients in the absence of a panic attack: reduction by a selective serotonin reuptake inhibitor
    Murray Esler
    Baker Heart Research Institute, Melbourne, Vic, Australia
    Stress 10:295-304. 2007
    ....
  10. ncbi request reprint Gender differences in sympathetic nervous activity: influence of body mass and blood pressure
    Elisabeth Lambert
    Human Neurotransmitters Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia
    J Hypertens 25:1411-9. 2007
    ..We tested whether the sympathetic nervous system was differently affected in men and women by the body mass index (BMI), BP, leptin and weight loss...
  11. doi request reprint Altered sympathetic nervous reactivity and norepinephrine transporter expression in patients with postural tachycardia syndrome
    Elisabeth Lambert
    Human Neurotransmitter Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia
    Circ Arrhythm Electrophysiol 1:103-9. 2008
    ..Clinical observations in patients with postural tachycardia syndrome (POTS) suggest abnormal sympathetic nervous system activity and a dysfunction of the norepinephrine (NE) transporter (NET)...
  12. ncbi request reprint Differing pattern of sympathoexcitation in normal-weight and obesity-related hypertension
    Elisabeth Lambert
    Human Neurotransmitters Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia
    Hypertension 50:862-8. 2007
    ..The underlying central nervous system mechanism and the adverse consequences of the 2 modes of sympathetic activation may differ...
  13. ncbi request reprint Extra-adipocyte leptin release in human obesity and its relation to sympathoadrenal function
    Nina Eikelis
    Baker Heart Research Institute, Melbourne University, Melbourne, Victoria 8008, Australia
    Am J Physiol Endocrinol Metab 286:E744-52. 2004
    ..9 +/- 1.4 vs. 5.3 +/- 2.2 ng/min (P = 0.042). These results suggest that leptin is released within the brain and at an increased rate in obese humans, in whom activation of brain serotonergic and NPY mechanisms also exists...
  14. doi request reprint Sympathetic nervous system activity is associated with obesity-induced subclinical organ damage in young adults
    Elisabeth Lambert
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Road Central, Melbourne, Victoria 8008, Australia
    Hypertension 56:351-8. 2010
    ..Sympathetic activity is closely associated with cardiovascular and renal alterations observed in these subjects...
  15. pmc Jugular venous overflow of noradrenaline from the brain: a neurochemical indicator of cerebrovascular sympathetic nerve activity in humans
    David A Mitchell
    Human Neurotransmitter Laboratory, Baker Medical Research Institute, Prahran, Victoria, Australia
    J Physiol 587:2589-97. 2009
    ..We suggest that measurements of transcranial plasma noradrenaline spillover have utility as a method for assessing the sympathetic nerve activity of the cerebral vasculature...
  16. ncbi request reprint Decreased renal sympathetic activity in response to cardiac unloading with nitroglycerin in patients with heart failure
    Magnus Petersson
    Department of Cardiology, The Cardiovascular Institute, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Eur J Heart Fail 7:1003-10. 2005
    ..To examine changes in renal sympathetic outflow in response to cardiac unloading with nitroglycerin (GTN) in patients with chronic heart failure (CHF) and healthy subjects (HS)...
  17. doi request reprint Chronic mental stress is a cause of essential hypertension: presence of biological markers of stress
    Murray Esler
    Baker Heart Research Institute, Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 35:498-502. 2008
    ..This judgement was reached after consideration of the epidemiological evidence, but in particular after review of the specific elements of the neural pathophysiology of essential hypertension, described above...
  18. doi request reprint Ghrelin modulates sympathetic nervous system activity and stress response in lean and overweight men
    Elisabeth Lambert
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Road Central, Melbourne, Victoria 8008, Australia
    Hypertension 58:43-50. 2011
    ..These responses may represent a combination of peripheral (baroreflex-mediated) and central effects of ghrelin...
  19. doi request reprint Recurrent postural vasovagal syncope: sympathetic nervous system phenotypes
    Gautam Vaddadi
    Human Neurotransmitter Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Circ Arrhythm Electrophysiol 4:711-8. 2011
    ..We investigated neural circulatory control in these 2 phenotypes...
  20. ncbi request reprint Rilmenidine sympatholytic activity preserves mental stress, orthostatic sympathetic responses and adrenaline secretion
    Murray Esler
    Baker Heart Research Institute, Melbourne, Victoria, Australia
    J Hypertens 22:1529-34. 2004
    ..Acute sympathetic nervous activation is a proven trigger for adverse cardiovascular events. Accordingly, antihypertensive drugs inhibiting sympathetic outflow represent a theoretically attractive therapeutic option...
  21. ncbi request reprint The neuronal noradrenaline transporter, anxiety and cardiovascular disease
    Murray Esler
    Baker Heart Research Institute, Melbourne, Australia
    J Psychopharmacol 20:60-6. 2006
    ....
  22. ncbi request reprint Cardiac sympathetic nerve biology and brain monoamine turnover in panic disorder
    Murray Esler
    Baker Heart Research Institute, PO Box 6492, St Kilda Road Central, Melbourne, Victoria 8008, Australia
    Ann N Y Acad Sci 1018:505-14. 2004
    ....
  23. doi request reprint Association between the sympathetic firing pattern and anxiety level in patients with the metabolic syndrome and elevated blood pressure
    Elisabeth Lambert
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    J Hypertens 28:543-50. 2010
    ....
  24. ncbi request reprint Increased cardiac sympathetic drive in renovascular hypertension
    Magnus J Petersson
    Department of Cardiology, Sahlgrenska University Hospital, Goteborg, Sweden
    J Hypertens 20:1181-7. 2002
    ..Patients with renovascular hypertension (RVH) have high cardiovascular mortality and morbidity. In these patients, overall sympathetic nerve activity is increased. It is unknown, however, whether this increase also involves the heart...
  25. ncbi request reprint Regional sympathetic effects of low-dose clonidine in heart failure
    Anuradha Aggarwal
    Baker Medical Research Institute, University of Melbourne, Melbourne, Victoria, Australia
    Hypertension 41:553-7. 2003
    ..In addition to the beneficial effects of antiadrenergic therapy in the heart, the renal sympatholytic effect may counter the salt and water retention that is a hallmark of the condition...
  26. pmc Neurocardiac dysregulation and neurogenic arrhythmias in a transgenic mouse model of Huntington's disease
    Helen Kiriazis
    Baker IDI Heart and Diabetes Institute, 75 Commercial Road, Melbourne, Victoria 3004, Australia
    J Physiol 590:5845-60. 2012
    ..Collectively, R6/1 mice exhibit profound ANS-cardiac dysfunction involving both sympathetic and parasympathetic limbs, that may be related to altered central autonomic pathways and lead to cardiac arrhythmias and sudden death...
  27. doi request reprint Epigenetic modification of the norepinephrine transporter gene in postural tachycardia syndrome
    Richard Bayles
    Baker IDI Heart and Diabetes Institute, The University of Melbourne, Melbourne, Victoria 3004, Australia
    Arterioscler Thromb Vasc Biol 32:1910-6. 2012
    ..A coding mutation in the norepinephrine transporter gene (SLC6A2) sequence has been reported in 1 family kindred only. The goal of the present study was to further characterize the role and regulation of the SLC6A2 gene in POTS...
  28. pmc Single-unit analysis of sympathetic nervous discharges in patients with panic disorder
    Elisabeth Lambert
    Human Neurotransmitter Laboratory, Baker Heart Research Institute, PO Box 6492 St Kilda Road Central, Melbourne, Victoria, Australia
    J Physiol 570:637-43. 2006
    ..Quantification from single vasoconstrictor unit recording provides evidence of a disturbed sympathetic firing pattern in patients with panic disorder...
  29. doi request reprint Single-unit sympathetic discharge pattern in pathological conditions associated with elevated cardiovascular risk
    Elisabeth Lambert
    Human Neurotransmitters Laboratory, Baker Heart Research Institute, Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 35:503-7. 2008
    ..4. Single-unit methodology may represent a major step forward in the understanding of the link between disturbed sympathetic nerve firing and associated cardiovascular risk...
  30. ncbi request reprint The influence of aging on the human sympathetic nervous system and brain norepinephrine turnover
    Murray Esler
    Baker Medical Research Institute, Melbourne, Victoria 8008, Australia
    Am J Physiol Regul Integr Comp Physiol 282:R909-16. 2002
    ....
  31. ncbi request reprint Long-term outcome in relation to renal sympathetic activity in patients with chronic heart failure
    Magnus Petersson
    Department of Cardiology, The Cardiovascular Institute, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Eur Heart J 26:906-13. 2005
    ..We assessed the hypothesis that renal noradrenaline (NA) spillover is a predictor of the combined endpoint of all-cause mortality and heart transplantation in CHF...
  32. ncbi request reprint Influence of ageing on the sympathetic nervous system and adrenal medulla at rest and during stress
    Murray Esler
    Baker Medical Research Institute, Melbourne, Australia
    Biogerontology 3:45-9. 2002
    ..Sympathetic nervous responses with stressors were augmented. Conversely, adrenal medullary release of epinephrine was subnormal in the elderly, at rest and during stress...
  33. ncbi request reprint NPY and NPY Y1 receptor effects on noradrenaline overflow from the rat brain in vitro
    Jacqueline A Hastings
    Baker Heart Research Institute, Human Neurotransmitter Laboratory, P O Box 6492, St Kilda Rd Central, Melbourne, Victoria 8008, Australia
    Regul Pept 120:107-12. 2004
    ....
  34. ncbi request reprint Preserved left ventricular structure and function in mice with cardiac sympathetic hyperinnervation
    Helen Kiriazis
    Experimental Cardiology Laboratory, Baker Heart Research Institute, P O Box 6492 St Kilda Road Central, Melbourne, Victoria 8008, Australia
    Am J Physiol Heart Circ Physiol 289:H1359-65. 2005
    ..In conclusion, overexpression of NGF in heart leads to sympathetic hyperinnervation that is not associated with detrimental effects on LV performance and is likely due to concomitantly enhanced norepinephrine neuronal uptake...
  35. ncbi request reprint Mechanisms of sympathetic activation in obesity-related hypertension
    Murray Esler
    Baker Heart Research Institute, PO Box 6492 St Kilda Rd Central, Melbourne, Victoria 8008, Australia
    Hypertension 48:787-96. 2006
  36. pmc Methylation of the SLC6a2 gene promoter in major depression and panic disorder
    Richard Bayles
    Baker IDI Heart and Diabetes Institute, Melbourne, Australia
    PLoS ONE 8:e83223. 2013
    ..Further in-depth analysis of alternative mechanisms of transcriptional regulation of the SLC6a2 gene in human health and disease would be of value. ..
  37. doi request reprint Renal denervation: a potential new treatment modality for polycystic ovary syndrome?
    Markus P Schlaich
    Neurovascular Hypertension and Kidney Disease Laboratory, Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Road Central, Melbourne, VIC 8008, Australia
    J Hypertens 29:991-6. 2011
    ..Here we report on the effects of renal denervation on hemodynamic, metabolic, and renal parameters in two obese PCOS patients with hypertension...
  38. ncbi request reprint Psychophysiological mechanisms in panic disorder: a correlative analysis of noradrenaline spillover, neuronal noradrenaline reuptake, power spectral analysis of heart rate variability, and psychological variables
    Marlies E Alvarenga
    Faculty of Medicine, Monash University and Cardiovascular Neurosciences Division, Baker Heart Research Institute, Baker Heart Research Institute, Prahran, Victoria, Australia
    Psychosom Med 68:8-16. 2006
    ..We estimated cardiac vagal activity from heart rate variability (HRV) measurements and quantified sympathetic nervous system (SNS) activity using plasma noradrenaline tracer kinetics methodology...
  39. ncbi request reprint Regional norepinephrine spillover in response to angiotensin-converting enzyme inhibition in healthy subjects
    Mats Johansson
    Department of Clinical Physiology, Cardiovascular Institute, Goteborg University, Sahlgrenska University Hospital, Goteborg, Sweden
    J Hypertens 21:1371-5. 2003
    ..The aim of the present study was to investigate overall, cardiac and renal sympathetic nerve activity, before and after intravenous enalaprilat, in healthy normotensive subjects without an activated RAS...
  40. doi request reprint Sympathetic and vascular dysfunction in adult patients with Fontan circulation
    Elisabeth Lambert
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
    Int J Cardiol 167:1333-8. 2013
    ..Patients with Fontan circulation are known to have increased systemic vascular resistance (SVR) however the underlying mechanisms are uncertain. We therefore further investigated the haemodynamic and vascular profile of Fontan patients...
  41. ncbi request reprint Autonomic control of the heart and renal vascular bed during autonomic dysreflexia in high spinal cord injury
    Sinsia A Gao
    Department of Clinical Physiology, Sahlgrenska University Hospital, 41345 Goteborg, Sweden
    Clin Auton Res 12:457-64. 2002
    ..This activation was counterbalanced by an increased vagal activity as evidenced by reduction of the heart rate...
  42. ncbi request reprint Cerebral noradrenaline spillover and its relation to muscle sympathetic nervous activity in healthy human subjects
    G W Lambert
    Human Autonomic Function Laboratory, Baker Medical Research Institute, Prahran, Vic, Australia
    J Auton Nerv Syst 64:57-64. 1997
    ....
  43. ncbi request reprint Morning surge in blood pressure is associated with reactivity of the sympathetic nervous system
    Elisabeth A Lambert
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Am J Hypertens 27:783-92. 2014
    ..We determined whether the response of the SNS to a cold pressor test predicted the BP morning surge...
  44. ncbi request reprint Cardiac response to norepinephrine and sympathetic nerve stimulation following experimental subarachnoid hemorrhage
    Elisabeth Lambert
    Human Neurotransmitter, Baker Medical Research Institute, Melbourne, Victoria, Australia
    J Neurol Sci 198:43-50. 2002
    ..However, hypersensitivity of the heart may not be explained by changes in norepinephrine release or by beta-receptor density...
  45. ncbi request reprint Influence of leptin on neurotransmitter overflow from the rat brain in vitro
    Jacqueline A Hastings
    Baker Medical Research Institute, Human Neurotransmitter Laboratory, P O Box 6492, Victoria 8008, Melbourne, Australia
    Regul Pept 103:67-74. 2002
    ..This study lends support to the notion of a complex interaction of the leptinergic and brain neurotransmitters involved in the control of feeding and energy metabolism...
  46. ncbi request reprint Reduced spontaneous baroreceptor sensitivity in patients with renovascular hypertension
    Sinsia A Gao
    Department of Clinical Physiology, Goteborg University, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    J Hypertens 20:111-6. 2002
    ....
  47. ncbi request reprint Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and Angiotensin neuromodulation
    Markus P Schlaich
    Department of Medicine IV, University of Erlangen Nuernberg, Krankenhausstr 12, 91054 Erlangen, Germany
    Hypertension 43:169-75. 2004
    ....
  48. ncbi request reprint The 'adrenaline hypothesis' of hypertension revisited: evidence for adrenaline release from the heart of patients with essential hypertension
    M S Rumantir
    Baker Medical Research Institute and Alfred Baker Medical Unit, Alfred Hospital, Melbourne, Australia
    J Hypertens 18:717-23. 2000
    ....
  49. ncbi request reprint Central nervous system norepinephrine metabolism in hypertension
    G W Lambert
    Human Neurotransmitters Laboratory, Baker Medical Research Institute, PO Box 6492, St Kilda Road Central, Melbourne, Victoria 8008, Australia
    Curr Hypertens Rep 2:302-10. 2000
    ....
  50. ncbi request reprint Surgical vs conventional therapy for weight loss treatment of obstructive sleep apnea: a randomized controlled trial
    John B Dixon
    Obesity Research Unit, Department of General Practice, Monash University, Melbourne, Victoria, Australia
    JAMA 308:1142-9. 2012
    ..Obstructive sleep apnea (OSA) is strongly related to obesity. Weight loss is recommended as part of the overall management plan for obese patients diagnosed with OSA...
  51. ncbi request reprint Chronic placental insufficiency affects retinal development in the guinea pig
    Michelle Loeliger
    Department of Anatomy and Cell Biology, University of Melbourne, Victoria, Australia
    Invest Ophthalmol Vis Sci 45:2361-7. 2004
    ....
  52. doi request reprint Peripheral chemoreflex activation contributes to sympathetic baroreflex impairment in chronic heart failure
    Fabien Despas
    Institut National de la Sante et de la Recherche Medicale, UMR 1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France
    J Hypertens 30:753-60. 2012
    ..Chemoreflex-mediated sympathetic activation contributes to both initiation and progression of chronic heart failure (CHF)...
  53. ncbi request reprint Total norepinephrine spillover, muscle sympathetic nerve activity and heart-rate spectral analysis in a patient with dopamine beta-hydroxylase deficiency
    J M Thompson
    Alfred Baker Medical Unit, Alfred Hospital, Victoria, Australia
    J Auton Nerv Syst 55:198-206. 1995
    ....
  54. doi request reprint Cardiac autonomic function in adolescents operated by arterial switch surgery
    Cecilia Falkenberg
    Division of Paediatric Cardiology, Institute of Clinical Sciences, Sahlgrenska University Hospital, Gothenburg University, Sweden
    Int J Cardiol 168:1887-93. 2013
    ..We hypothesised that i) cardiac norepinephrine (NE) kinetics and ii) arterial baroreflex sensitivity (BRS), reflecting sympathetic activity and vagal function respectively, are altered in this group...
  55. pmc Decreased catecholamine degradation associates with shock and kidney injury after cardiac surgery
    Anja Haase-Fielitz
    Department of Intensive Care, Austin Health, Melbourne, Australia
    J Am Soc Nephrol 20:1393-403. 2009
    ..In summary, this study identifies COMT LL homozygosity as an independent risk factor for shock, AKI, and hospital stay after cardiac surgery. (ClinicalTrials.gov number, NCT00334009)...
  56. ncbi request reprint Cardiovascular actions of the venom from the Irukandji (Carukia barnesi) jellyfish: effects in human, rat and guinea-pig tissues in vitro and in pigs in vitro
    Kenneth D Winkel
    Department of Pharmacology, The University of Melbourne, Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 32:777-88. 2005
    ..The venom may also contain a 'direct' vasoconstrictor component. These observations explain, at least in part, the clinical features of the potentially deadly Irukandji syndrome...
  57. ncbi request reprint Sex differences in postnatal growth and renal development in offspring of rabbit mothers with chronic secondary hypertension
    D Maduwegedera
    Department of Physiology, Monash University, Victoria, Australia
    Am J Physiol Regul Integr Comp Physiol 292:R706-14. 2007
    ..The impact of a stimulated maternal renin-angiotensin system in the 2K-1W model of hypertension may influence development of the renal sympathetic nerves and contribute to programming of adult hypertension...
  58. ncbi request reprint Angiotensin II and norepinephrine release: interaction and effects on the heart
    Markus P Schlaich
    Department of Medicine IV, University of Erlangen Nuernberg, Germany
    J Hypertens 23:1077-82. 2005
    ..We investigated whether such an interaction is evident in the human heart and whether it has an impact on left ventricular (LV) structure...
  59. ncbi request reprint Sympathetic activation and inflammatory response in patients with subarachnoid haemorrhage
    Silvana Naredi
    Department of Anaesthesiology and Intensive Care, Umea University Hospital, Umea, Sweden
    Intensive Care Med 32:1955-61. 2006
    ..The aim of this study was to evaluate the correlation between sympathetic nervous activation and the immune response in patients following subarachnoid haemorrhage (SAH)...