Clinton R Bruce


Affiliation: Baker Heart Research Institute
Country: Australia


  1. request reprint
    Bruce C, Brolin C, Turner N, Cleasby M, van der Leij F, Cooney G, et al. Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification. Am J Physiol Endocrinol Metab. 2007;292:E1231-7 pubmed
    ..05). These studies demonstrate that acute overexpression of CPT I in muscle leads to a repartitioning of FAs away from esterification and toward oxidation and highlight the importance of CPT I in regulating muscle FA metabolism. ..
  2. Bruce C, Hoy A, Turner N, Watt M, Allen T, Carpenter K, et al. Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance. Diabetes. 2009;58:550-8 pubmed publisher