Katerina Zavitsanou

Summary

Affiliation: Australian Nuclear Science and Technology Organisation
Country: Australia

Publications

  1. ncbi request reprint Detection of apoptotic cell death in the thymus of dexamethasone treated rats using [123I]annexin V and in situ oligonucleotide ligation
    Katerina Zavitsanou
    Radiopharmaceutical Research Institute, Australian Nuclear Science and Technology Organisation, PMB 1, Menai, Sydney, NSW 2234, Australia
    J Mol Histol 38:313-9. 2007
  2. ncbi request reprint M2/M4 muscarinic receptor binding in the anterior cingulate cortex in schizophrenia and mood disorders
    Katerina Zavitsanou
    Radiopharmaceuticals R and D, Australian Nuclear Science and Technology Organisation ANSTO, PMB 1, Menai, Sydney, NSW 2234, Australia
    Brain Res Bull 65:397-403. 2005
  3. ncbi request reprint Effects of typical and atypical antipsychotic drugs on rat brain muscarinic receptors
    Katerina Zavitsanou
    Australian Nuclear Science and Technology Organisation, Radiopharmaceuticals Research Institute, PMB 1, Menai, NSW, 2234 Sydney, NSW, Australia
    Neurochem Res 32:525-32. 2007
  4. ncbi request reprint Rapid cortico-limbic alterations in AMPA receptor densities after administration of PCP: implications for schizophrenia
    Katerina Zavitsanou
    Australian Nuclear Science and Technology Organisation ANSTO, Sydney, NSW, Australia
    J Chem Neuroanat 36:71-6. 2008
  5. ncbi request reprint Prenatal poly I:C age-dependently alters cannabinoid type 1 receptors in offspring: a longitudinal small animal PET study using [(18)F]MK-9470
    Mathieu Verdurand
    Schizophrenia Research Institute, Sydney, Australia ANSTO LifeSciences, ANSTO, PMB 1 Menai, NSW 2234, Australia Neuroscience Research Center Lyon CRNL, CNRS UMR5292, INSERM U1028, BioRaN Team, Lyon, France Electronic address
    Exp Neurol 257:162-9. 2014
  6. doi request reprint Increased brain metabolism after acute administration of the synthetic cannabinoid HU210: a small animal PET imaging study with 18F-FDG
    Vu H Nguyen
    ANSTO LifeSciences, Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW 2234, Australia
    Brain Res Bull 87:172-9. 2012
  7. ncbi request reprint Investigation of m1/m4 muscarinic receptors in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depression disorder
    Katerina Zavitsanou
    Neuroscience Institute of Schizophrenia and Allied Disorders, University of Wollongong, NSW, Australia
    Neuropsychopharmacology 29:619-25. 2004
  8. doi request reprint Cannabinoid effects on CB1 receptor density in the adolescent brain: an autoradiographic study using the synthetic cannabinoid HU210
    Victoria S Dalton
    Schizophrenia Research Institute, Sydney, Australia
    Synapse 64:845-54. 2010
  9. pmc Increases in [3H]muscimol and [3H]flumazenil binding in the dorsolateral prefrontal cortex in schizophrenia are linked to α4 and γ2S mRNA levels respectively
    Mathieu Verdurand
    Schizophrenia Research Institute, Sydney, Australia
    PLoS ONE 8:e52724. 2013
  10. doi request reprint Differential treatment regimen-related effects of HU210 on CB(1) and D(2)-like receptor functionality in the rat basal ganglia
    Vu H Nguyen
    Lifesciences Division, Australian Nuclear Science and Technology Organisation, Lucas Heights, N S W, Australia
    Pharmacology 89:64-73. 2012

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Detection of apoptotic cell death in the thymus of dexamethasone treated rats using [123I]annexin V and in situ oligonucleotide ligation
    Katerina Zavitsanou
    Radiopharmaceutical Research Institute, Australian Nuclear Science and Technology Organisation, PMB 1, Menai, Sydney, NSW 2234, Australia
    J Mol Histol 38:313-9. 2007
    ..We conclude that the specificity of the apoptotic signal provided by isotopic methods in vivo would always require confirmation by complementary in vitro techniques that verify the assessment of ongoing apoptosis accurately...
  2. ncbi request reprint M2/M4 muscarinic receptor binding in the anterior cingulate cortex in schizophrenia and mood disorders
    Katerina Zavitsanou
    Radiopharmaceuticals R and D, Australian Nuclear Science and Technology Organisation ANSTO, PMB 1, Menai, Sydney, NSW 2234, Australia
    Brain Res Bull 65:397-403. 2005
    ....
  3. ncbi request reprint Effects of typical and atypical antipsychotic drugs on rat brain muscarinic receptors
    Katerina Zavitsanou
    Australian Nuclear Science and Technology Organisation, Radiopharmaceuticals Research Institute, PMB 1, Menai, NSW, 2234 Sydney, NSW, Australia
    Neurochem Res 32:525-32. 2007
    ..These findings suggest that muscarinic receptors and limbic brain regions such as hippocampus and amygdala might represent common targets that mediate beneficial clinical effects of antipsychotic drugs...
  4. ncbi request reprint Rapid cortico-limbic alterations in AMPA receptor densities after administration of PCP: implications for schizophrenia
    Katerina Zavitsanou
    Australian Nuclear Science and Technology Organisation ANSTO, Sydney, NSW, Australia
    J Chem Neuroanat 36:71-6. 2008
    ....
  5. ncbi request reprint Prenatal poly I:C age-dependently alters cannabinoid type 1 receptors in offspring: a longitudinal small animal PET study using [(18)F]MK-9470
    Mathieu Verdurand
    Schizophrenia Research Institute, Sydney, Australia ANSTO LifeSciences, ANSTO, PMB 1 Menai, NSW 2234, Australia Neuroscience Research Center Lyon CRNL, CNRS UMR5292, INSERM U1028, BioRaN Team, Lyon, France Electronic address
    Exp Neurol 257:162-9. 2014
    ..The increased CB1R expression in adulthood following poly I:C mirrors the increased CB1R observed in patients with schizophrenia in post-mortem and in vivo PET studies. ..
  6. doi request reprint Increased brain metabolism after acute administration of the synthetic cannabinoid HU210: a small animal PET imaging study with 18F-FDG
    Vu H Nguyen
    ANSTO LifeSciences, Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW 2234, Australia
    Brain Res Bull 87:172-9. 2012
    ..The present results suggest that high-dose HU210 increases brain glucose metabolism in the rat brain shortly after administration, in line with normalised human in vivo studies, an effect that was no longer apparent 24 h later...
  7. ncbi request reprint Investigation of m1/m4 muscarinic receptors in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depression disorder
    Katerina Zavitsanou
    Neuroscience Institute of Schizophrenia and Allied Disorders, University of Wollongong, NSW, Australia
    Neuropsychopharmacology 29:619-25. 2004
    ..The changes observed in schizophrenia may contribute to dysfunctional ACC neural circuits...
  8. doi request reprint Cannabinoid effects on CB1 receptor density in the adolescent brain: an autoradiographic study using the synthetic cannabinoid HU210
    Victoria S Dalton
    Schizophrenia Research Institute, Sydney, Australia
    Synapse 64:845-54. 2010
    ..This reduced compensatory response may contribute to some acute behavioral effects, the pharmacological cross-tolerance and the long-lasting, adverse psychological consequences of cannabinoid exposure during adolescence...
  9. pmc Increases in [3H]muscimol and [3H]flumazenil binding in the dorsolateral prefrontal cortex in schizophrenia are linked to α4 and γ2S mRNA levels respectively
    Mathieu Verdurand
    Schizophrenia Research Institute, Sydney, Australia
    PLoS ONE 8:e52724. 2013
    ....
  10. doi request reprint Differential treatment regimen-related effects of HU210 on CB(1) and D(2)-like receptor functionality in the rat basal ganglia
    Vu H Nguyen
    Lifesciences Division, Australian Nuclear Science and Technology Organisation, Lucas Heights, N S W, Australia
    Pharmacology 89:64-73. 2012
    ....
  11. ncbi request reprint Receptor changes in brain tissue of rats treated as neonates with capsaicin
    Katerina Zavitsanou
    Radiopharmaceutical Research Institute, Australian Nuclear Science and Technology Organization ANSTO, Menai, New South Wales, Australia
    J Chem Neuroanat 39:248-55. 2010
    ....
  12. ncbi request reprint GABA(A) receptor density is altered by cannabinoid treatment in the hippocampus of adult but not adolescent rats
    Mathieu Verdurand
    Schizophrenia Research Institute, Sydney, Australia
    Brain Res 1351:238-45. 2010
    ..In addition, our results suggest that the adolescent brain does not display the same compensatory mechanisms that are activated in the adult brain following cannabinoid treatment...
  13. ncbi request reprint Immunohistochemical localisation of the NK1 receptor in the human amygdala: preliminary investigation in schizophrenia
    Judith Weidenhofer
    Neuroscience Institute of Schizophrenia and Allied Disorders, Sydney, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 30:1313-21. 2006
    ....
  14. ncbi request reprint Differential treatment regimen-related effects of cannabinoids on D1 and D2 receptors in adolescent and adult rat brain
    Victoria S Dalton
    Schizophrenia Research Institute, Sydney, Australia
    J Chem Neuroanat 40:272-80. 2010
    ..These results suggest that the adolescent rat brain does not display the same compensatory mechanisms activated in the adult brain following cannabinoid treatment...
  15. pmc Paranoid schizophrenia is characterized by increased CB1 receptor binding in the dorsolateral prefrontal cortex
    Victoria S Dalton
    ANSTO Life Sciences, Australian Nuclear Science and Technology Organization, Sydney, New South Wales, Australia
    Neuropsychopharmacology 36:1620-30. 2011
    ..Our findings confirm the existence of a CB(1)R dysregulation in SCZ and underline the need for further investigation of the role of this receptor particularly in those diagnosed with paranoid SCZ...
  16. pmc Comparison of Cannabinoid CB(1) Receptor Binding in Adolescent and Adult Rats: A Positron Emission Tomography Study Using [F]MK-9470
    Mathieu Verdurand
    Schizophrenia Research Institute, Sydney, Australia
    Int J Mol Imaging 2011:548123. 2011
    ..1, P < 0.0001). This ontogenetic pattern, suggesting increase of CB(1)R during the transition from adolescence to adulthood, is the opposite of most other neuroreceptor systems undergoing pruning during this period...
  17. ncbi request reprint Selective alterations in ionotropic glutamate receptors in the anterior cingulate cortex in schizophrenia
    Katerina Zavitsanou
    Neuroscience Institute of Schizophrenia and Allied Disorders, University of Wollongong, NSW, Australia
    Neuropsychopharmacology 27:826-33. 2002
    ..The findings add to a growing body of literature that supports a dysfunction of excitatory activity in the anterior cingulate cortex in schizophrenia...
  18. doi request reprint HU210-induced downregulation in cannabinoid CB1 receptor binding strongly correlates with body weight loss in the adult rat
    Victoria S Dalton
    Radiopharmaceuticals Research Institute, Australian Nuclear Science and Technology Organisation, PMB 1 Menai, Sydney, NSW, 2234, Australia
    Neurochem Res 34:1343-53. 2009
    ..0001) between body weight on day four and CB1 receptor binding were found in all brain regions examined suggesting that downregulation of CB1 receptors may contribute to the induction of tolerance to body weight loss induced by HU210...
  19. ncbi request reprint Olanzapine differentially affects 5-HT2Aand2C receptor mRNA expression in the rat brain
    Xu Feng Huang
    Neurobiology Research Centre of Metabolic and Psychiatric Disorders, School of Health Science, University of Wollongong, NSW, Australia
    Behav Brain Res 171:355-62. 2006
    ..5-HT(2C) receptor mRNA expressions were decreased in the substantia nigra. Correlations between 5-HT(2A) receptor mRNA expression and total food intake, weight gain and energy efficiency were observed...
  20. doi request reprint Neonatal lipopolysaccharide treatment has long-term effects on monoaminergic and cannabinoid receptors in the rat
    Katerina Zavitsanou
    School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia
    Synapse 67:290-9. 2013
    ....
  21. pmc Rapid changes in d1 and d2 dopamine receptor binding in striatal subregions after a single dose of phencyclidine
    Victoria S Dalton
    Schizophrenia Research Institute, Australian Nuclear Science and Technology Organisation, Sydney, Australia ANSTO LifeSciences, Australian Nuclear Science and Technology Organisation, Sydney, Australia
    Clin Psychopharmacol Neurosci 9:67-72. 2011
    ....
  22. ncbi request reprint Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia
    Katerina Zavitsanou
    Neuroscience Institute of Schizophrenia and Allied Disorders, University of Wollongong, Northfields Avenue, NSW 2522, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 28:355-60. 2004
    ..03). The present results support the suggestion that changes in the endogenous cannabinoid system in the ACC may be involved in the pathology of schizophrenia particularly in relation to negative symptoms...
  23. ncbi request reprint Opposing short- and long-term effects on muscarinic M1/4 receptor binding following chronic phencyclidine treatment
    Kelly A Newell
    School of Health Sciences, University of Wollongong, Wollongong, New South Wales, Australia
    J Neurosci Res 85:1358-63. 2007
    ..These findings in the long-term group are similar to those reported in post-mortem studies of patients suffering from schizophrenia...
  24. ncbi request reprint Ionotropic glutamate receptor binding in the posterior cingulate cortex in schizophrenia patients
    Kelly A Newell
    Neuroscience Institute of Schizophrenia and Allied Disorders, University of Wollongong, New South Wales, Australia
    Neuroreport 16:1363-7. 2005
    ..The fact that only the N-methyl-D-aspartate receptor densities are significantly altered suggests that this is unlikely to be caused by a simple decrease in glutamatergic transmission...
  25. ncbi request reprint Alterations of muscarinic and GABA receptor binding in the posterior cingulate cortex in schizophrenia
    Kelly A Newell
    Department of Biomedical Science, University of Wollongong, Northfields Avenue, NSW 2522, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 31:225-33. 2007
    ..Whilst the exact mechanism causing these alterations is not yet known, a possible increased acetylcholine and down regulated GABA stimulation in the PCC of schizophrenia is suggested...
  26. ncbi request reprint Dopamine transporter and D2 receptor binding densities in mice prone or resistant to chronic high fat diet-induced obesity
    Xu Feng Huang
    Department of Biomedical Science, University of Wollongong, NSW 2522, Australia
    Behav Brain Res 175:415-9. 2006
    ..D2 receptor density was significantly lower in the rostral part of caudate putamen in cDIO mice compared to cDR and LF mice...
  27. ncbi request reprint Effects of antipsychotic medication on muscarinic M1 receptor mRNA expression in the rat brain
    Mei Han
    Neurobiology Research Centre for Metabolic and Psychiatric Disorders, School of Health Sciences, University of Wollongong, Wollongong, New South Wales, Australia
    J Neurosci Res 86:457-64. 2008
    ....
  28. ncbi request reprint Neuropeptide Y mRNA expression levels following chronic olanzapine, clozapine and haloperidol administration in rats
    X F Huang
    Neurobiology Research Centre for Metabolic and Psychiatric Disorders, Department of Biomedical Science, University of Wollongong, Northfield Avenue, NSW 2522, Australia
    Neuropeptides 40:213-9. 2006
    ..The immediate decrease of NPY mRNA levels suggests an immediate reduction of NPY biosynthesis in response to these drugs...