Research Topics
Species | Katerina ZavitsanouSummaryAffiliation: Australian Nuclear Science and Technology Organisation Country: Australia Publications
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Detail Information
Publications
Detection of apoptotic cell death in the thymus of dexamethasone treated rats using [123I]annexin V and in situ oligonucleotide ligationKaterina Zavitsanou
Radiopharmaceutical Research Institute, Australian Nuclear Science and Technology Organisation, PMB 1, Menai, Sydney, NSW 2234, Australia
J Mol Histol 38:313-9. 2007..We conclude that the specificity of the apoptotic signal provided by isotopic methods in vivo would always require confirmation by complementary in vitro techniques that verify the assessment of ongoing apoptosis accurately...
M2/M4 muscarinic receptor binding in the anterior cingulate cortex in schizophrenia and mood disordersKaterina Zavitsanou
Radiopharmaceuticals R and D, Australian Nuclear Science and Technology Organisation ANSTO, PMB 1, Menai, Sydney, NSW 2234, Australia
Brain Res Bull 65:397-403. 2005....
Effects of typical and atypical antipsychotic drugs on rat brain muscarinic receptorsKaterina Zavitsanou
Australian Nuclear Science and Technology Organisation, Radiopharmaceuticals Research Institute, PMB 1, Menai, NSW, 2234 Sydney, NSW, Australia
Neurochem Res 32:525-32. 2007..These findings suggest that muscarinic receptors and limbic brain regions such as hippocampus and amygdala might represent common targets that mediate beneficial clinical effects of antipsychotic drugs...
Rapid cortico-limbic alterations in AMPA receptor densities after administration of PCP: implications for schizophreniaKaterina Zavitsanou
Australian Nuclear Science and Technology Organisation ANSTO, Sydney, NSW, Australia
J Chem Neuroanat 36:71-6. 2008....
Increased brain metabolism after acute administration of the synthetic cannabinoid HU210: a small animal PET imaging study with 18F-FDGVu H Nguyen
ANSTO LifeSciences, Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW 2234, Australia
Brain Res Bull 87:172-9. 2012..The present results suggest that high-dose HU210 increases brain glucose metabolism in the rat brain shortly after administration, in line with normalised human in vivo studies, an effect that was no longer apparent 24 h later...
Investigation of m1/m4 muscarinic receptors in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depression disorderKaterina Zavitsanou
Neuroscience Institute of Schizophrenia and Allied Disorders, University of Wollongong, NSW, Australia
Neuropsychopharmacology 29:619-25. 2004..The changes observed in schizophrenia may contribute to dysfunctional ACC neural circuits...
Cannabinoid effects on CB1 receptor density in the adolescent brain: an autoradiographic study using the synthetic cannabinoid HU210Victoria S Dalton
Schizophrenia Research Institute, Sydney, Australia
Synapse 64:845-54. 2010..This reduced compensatory response may contribute to some acute behavioral effects, the pharmacological cross-tolerance and the long-lasting, adverse psychological consequences of cannabinoid exposure during adolescence...
Differential treatment regimen-related effects of HU210 on CB(1) and D(2)-like receptor functionality in the rat basal gangliaVu H Nguyen
Lifesciences Division, Australian Nuclear Science and Technology Organisation, Lucas Heights, N S W, Australia
Pharmacology 89:64-73. 2012....
Receptor changes in brain tissue of rats treated as neonates with capsaicinKaterina Zavitsanou
Radiopharmaceutical Research Institute, Australian Nuclear Science and Technology Organization ANSTO, Menai, New South Wales, Australia
J Chem Neuroanat 39:248-55. 2010....
Immunohistochemical localisation of the NK1 receptor in the human amygdala: preliminary investigation in schizophreniaJudith Weidenhofer
Neuroscience Institute of Schizophrenia and Allied Disorders, Sydney, Australia
Prog Neuropsychopharmacol Biol Psychiatry 30:1313-21. 2006....
GABA(A) receptor density is altered by cannabinoid treatment in the hippocampus of adult but not adolescent ratsMathieu Verdurand
Schizophrenia Research Institute, Sydney, Australia
Brain Res 1351:238-45. 2010..In addition, our results suggest that the adolescent brain does not display the same compensatory mechanisms that are activated in the adult brain following cannabinoid treatment...
Differential treatment regimen-related effects of cannabinoids on D1 and D2 receptors in adolescent and adult rat brainVictoria S Dalton
Schizophrenia Research Institute, Sydney, Australia
J Chem Neuroanat 40:272-80. 2010..These results suggest that the adolescent rat brain does not display the same compensatory mechanisms activated in the adult brain following cannabinoid treatment...
Paranoid schizophrenia is characterized by increased CB1 receptor binding in the dorsolateral prefrontal cortexVictoria S Dalton
ANSTO Life Sciences, Australian Nuclear Science and Technology Organization, Sydney, New South Wales, Australia
Neuropsychopharmacology 36:1620-30. 2011..Our findings confirm the existence of a CB(1)R dysregulation in SCZ and underline the need for further investigation of the role of this receptor particularly in those diagnosed with paranoid SCZ...
Comparison of Cannabinoid CB(1) Receptor Binding in Adolescent and Adult Rats: A Positron Emission Tomography Study Using [F]MK-9470Mathieu Verdurand
Schizophrenia Research Institute, Sydney, Australia
Int J Mol Imaging 2011:548123. 2011..1, P < 0.0001). This ontogenetic pattern, suggesting increase of CB(1)R during the transition from adolescence to adulthood, is the opposite of most other neuroreceptor systems undergoing pruning during this period...
Selective alterations in ionotropic glutamate receptors in the anterior cingulate cortex in schizophreniaKaterina Zavitsanou
Neuroscience Institute of Schizophrenia and Allied Disorders, University of Wollongong, NSW, Australia
Neuropsychopharmacology 27:826-33. 2002..The findings add to a growing body of literature that supports a dysfunction of excitatory activity in the anterior cingulate cortex in schizophrenia...
HU210-induced downregulation in cannabinoid CB1 receptor binding strongly correlates with body weight loss in the adult ratVictoria S Dalton
Radiopharmaceuticals Research Institute, Australian Nuclear Science and Technology Organisation, PMB 1 Menai, Sydney, NSW, 2234, Australia
Neurochem Res 34:1343-53. 2009..0001) between body weight on day four and CB1 receptor binding were found in all brain regions examined suggesting that downregulation of CB1 receptors may contribute to the induction of tolerance to body weight loss induced by HU210...
Olanzapine differentially affects 5-HT2Aand2C receptor mRNA expression in the rat brainXu-Feng Huang
Neurobiology Research Centre of Metabolic and Psychiatric Disorders, School of Health Science, University of Wollongong, NSW, Australia
Behav Brain Res 171:355-62. 2006..5-HT(2C) receptor mRNA expressions were decreased in the substantia nigra. Correlations between 5-HT(2A) receptor mRNA expression and total food intake, weight gain and energy efficiency were observed...
Ionotropic glutamate receptor binding in the posterior cingulate cortex in schizophrenia patientsKelly A Newell
Neuroscience Institute of Schizophrenia and Allied Disorders, University of Wollongong, New South Wales, Australia
Neuroreport 16:1363-7. 2005..The fact that only the N-methyl-D-aspartate receptor densities are significantly altered suggests that this is unlikely to be caused by a simple decrease in glutamatergic transmission...
Opposing short- and long-term effects on muscarinic M1/4 receptor binding following chronic phencyclidine treatmentKelly A Newell
School of Health Sciences, University of Wollongong, Wollongong, New South Wales, Australia
J Neurosci Res 85:1358-63. 2007..These findings in the long-term group are similar to those reported in post-mortem studies of patients suffering from schizophrenia...
Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophreniaKaterina Zavitsanou
Neuroscience Institute of Schizophrenia and Allied Disorders, University of Wollongong, Northfields Avenue, NSW 2522, Australia
Prog Neuropsychopharmacol Biol Psychiatry 28:355-60. 2004..03). The present results support the suggestion that changes in the endogenous cannabinoid system in the ACC may be involved in the pathology of schizophrenia particularly in relation to negative symptoms...
Alterations of muscarinic and GABA receptor binding in the posterior cingulate cortex in schizophreniaKelly A Newell
Department of Biomedical Science, University of Wollongong, Northfields Avenue, NSW 2522, Australia
Prog Neuropsychopharmacol Biol Psychiatry 31:225-33. 2007..Whilst the exact mechanism causing these alterations is not yet known, a possible increased acetylcholine and down regulated GABA stimulation in the PCC of schizophrenia is suggested...
Neuropeptide Y mRNA expression levels following chronic olanzapine, clozapine and haloperidol administration in ratsX F Huang
Neurobiology Research Centre for Metabolic and Psychiatric Disorders, Department of Biomedical Science, University of Wollongong, Northfield Avenue, NSW 2522, Australia
Neuropeptides 40:213-9. 2006..The immediate decrease of NPY mRNA levels suggests an immediate reduction of NPY biosynthesis in response to these drugs...
Effects of antipsychotic medication on muscarinic M1 receptor mRNA expression in the rat brainMei Han
Neurobiology Research Centre for Metabolic and Psychiatric Disorders, School of Health Sciences, University of Wollongong, Wollongong, New South Wales, Australia
J Neurosci Res 86:457-64. 2008....
Dopamine transporter and D2 receptor binding densities in mice prone or resistant to chronic high fat diet-induced obesityXu Feng Huang
Department of Biomedical Science, University of Wollongong, NSW 2522, Australia
Behav Brain Res 175:415-9. 2006..D2 receptor density was significantly lower in the rostral part of caudate putamen in cDIO mice compared to cDR and LF mice...
