P Sah

Summary

Affiliation: Australian National University
Country: Australia

Publications

  1. ncbi request reprint Excitatory synaptic transmission in the lateral and central amygdala
    P Sah
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia
    Ann N Y Acad Sci 985:67-77. 2003
  2. ncbi request reprint The amygdaloid complex: anatomy and physiology
    P Sah
    School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia
    Physiol Rev 83:803-34. 2003
  3. ncbi request reprint Calcium-activated potassium currents in mammalian neurons
    P Sah
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra, ACT
    Clin Exp Pharmacol Physiol 27:657-63. 2000
  4. ncbi request reprint Channels underlying neuronal calcium-activated potassium currents
    Pankaj Sah
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, G P O Box 334, Canberra, ACT 2601, Australia
    Prog Neurobiol 66:345-53. 2002
  5. ncbi request reprint GABA receptors inhibited by benzodiazepines mediate fast inhibitory transmission in the central amygdala
    A J Delaney
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra ACT 2601, Australia
    J Neurosci 19:9698-704. 1999
  6. doi request reprint Differential expression of glycine receptor subunits in the rat basolateral and central amygdala
    A J Delaney
    Queensland Brain Institute, The University of Queensland, University Drive, Brisbane, QLD 4072, Australia
    Neurosci Lett 469:237-42. 2010
  7. ncbi request reprint Morphological and electrophysiological properties of principal neurons in the rat lateral amygdala in vitro
    E S Faber
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia
    J Neurophysiol 85:714-23. 2001
  8. ncbi request reprint Pathway-specific targeting of GABA(A) receptor subtypes to somatic and dendritic synapses in the central amygdala
    A J Delaney
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra
    J Neurophysiol 86:717-23. 2001
  9. ncbi request reprint Neuroplasticity and psychiatry
    B D Gynther
    Vision Touch and Hearing Research Centre, Department of Physiology and Pharmacology, University of Queensland, Brisbane, Australia
    Aust N Z J Psychiatry 32:119-28. 1998
  10. doi request reprint Fear conditioning and long-term potentiation in the amygdala: what really is the connection?
    P Sah
    Queensland Brain Institute, University of Queensland, Queensland 4072, Australia
    Ann N Y Acad Sci 1129:88-95. 2008

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Excitatory synaptic transmission in the lateral and central amygdala
    P Sah
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia
    Ann N Y Acad Sci 985:67-77. 2003
    ..Synapses in the central nucleus activate NMDA receptors that contain NR1 and NR2B subunits, whereas synapses in the lateral nucleus contain receptors with both NR2A and NR2B subunits...
  2. ncbi request reprint The amygdaloid complex: anatomy and physiology
    P Sah
    School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia
    Physiol Rev 83:803-34. 2003
    ..In this review, we examine the anatomical and physiological substrates proposed to underlie amygdala function...
  3. ncbi request reprint Calcium-activated potassium currents in mammalian neurons
    P Sah
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra, ACT
    Clin Exp Pharmacol Physiol 27:657-63. 2000
    ..3. In the present review we describe the properties of the known types of calcium-activated potassium currents in mammalian neurons and indicate the relationship between macroscopic currents and particular single channels...
  4. ncbi request reprint Channels underlying neuronal calcium-activated potassium currents
    Pankaj Sah
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, G P O Box 334, Canberra, ACT 2601, Australia
    Prog Neurobiol 66:345-53. 2002
    ..In this review, we discuss the properties of the different types of calcium-activated potassium channels and the relationship between these channels and the macroscopic currents present in neurons...
  5. ncbi request reprint GABA receptors inhibited by benzodiazepines mediate fast inhibitory transmission in the central amygdala
    A J Delaney
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra ACT 2601, Australia
    J Neurosci 19:9698-704. 1999
    ..We conclude that a new type of ionotropic GABA receptor mediates fast inhibitory transmission in the central amygdala. This receptor may be a potential target for the development of new therapeutic strategies for anxiety disorders...
  6. doi request reprint Differential expression of glycine receptor subunits in the rat basolateral and central amygdala
    A J Delaney
    Queensland Brain Institute, The University of Queensland, University Drive, Brisbane, QLD 4072, Australia
    Neurosci Lett 469:237-42. 2010
    ....
  7. ncbi request reprint Morphological and electrophysiological properties of principal neurons in the rat lateral amygdala in vitro
    E S Faber
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia
    J Neurophysiol 85:714-23. 2001
    ....
  8. ncbi request reprint Pathway-specific targeting of GABA(A) receptor subtypes to somatic and dendritic synapses in the central amygdala
    A J Delaney
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra
    J Neurophysiol 86:717-23. 2001
    ..Thus benzodiazepines will have different modulatory effects on different inhibitory pathways in the central amygdala...
  9. ncbi request reprint Neuroplasticity and psychiatry
    B D Gynther
    Vision Touch and Hearing Research Centre, Department of Physiology and Pharmacology, University of Queensland, Brisbane, Australia
    Aust N Z J Psychiatry 32:119-28. 1998
    ..As this indicates that abnormal function produces long-term changes within the brain, a review of the neuroscience literature regarding neuroplasticity is warranted...
  10. doi request reprint Fear conditioning and long-term potentiation in the amygdala: what really is the connection?
    P Sah
    Queensland Brain Institute, University of Queensland, Queensland 4072, Australia
    Ann N Y Acad Sci 1129:88-95. 2008
    ..The evidence that links LTP in the amygdala with fear conditioning is reviewed...
  11. ncbi request reprint Use of murine mutants to study glycine receptor function
    R J Callister
    Neuroscience Group, School of Biomedical Sciences, Faculty of Medicine and Health Sciences, University of Newcastle, Callaghan, Australia
    Clin Exp Pharmacol Physiol 26:929-31. 1999
    ..The present review focuses on the use of another, quite different, approach: the use of murine mutants, spasmodic and spastic, to study the function of native glycine receptors at synaptic connections within the central nervous system...
  12. ncbi request reprint Synaptic activation of transient receptor potential channels by metabotropic glutamate receptors in the lateral amygdala
    E S L Faber
    The Queensland Brain Institute, School of Biomedical Sciences, University of Queensland, Brisbane, QLD 4072, Australia
    Neuroscience 137:781-94. 2006
    ....
  13. pmc Altered inhibitory synaptic transmission in superficial dorsal horn neurones in spastic and oscillator mice
    B A Graham
    School of Biomedical Sciences, Faculty of Health, The University of Newcastle, Callaghan, NSW 2308, Australia
    J Physiol 551:905-16. 2003
    ..Furthermore, the spastic mutation results in a compensatory increase in GABAAergic transmission in SFDH neurones, a form of inhibitory synaptic plasticity absent in the oscillator mouse...
  14. doi request reprint Latent stem and progenitor cells in the hippocampus are activated by neural excitation
    Tara L Walker
    Queensland Brain Institute, The University of Queensland, Brisbane, Queensland 4072, Australia
    J Neurosci 28:5240-7. 2008
    ..Because the latent population is also demonstrated to reside in the aged animal, defining the precise mechanisms that underlie its activation may provide a means to combat the cognitive deficits associated with a decline in neurogenesis...
  15. doi request reprint Competition between calcium-activated K+ channels determines cholinergic action on firing properties of basolateral amygdala projection neurons
    John M Power
    Queensland Brain Institute, The University of Queensland, St Lucia, Queensland 4072, Australia
    J Neurosci 28:3209-20. 2008
    ..These results suggest that competition between cholinergic suppression of the sI(AHP) and cholinergic activation of the SK channels shapes the AHP and spike-frequency adaptation...
  16. ncbi request reprint Noradrenaline modulates transmission at a central synapse by a presynaptic mechanism
    Andrew J Delaney
    The Queensland Brain Institute, The University of Queensland, QLD 4072 Australia
    Neuron 56:880-92. 2007
    ....
  17. pmc Bidirectional synaptic plasticity at nociceptive afferents in the rat central amygdala
    Mikel Lopez de Armentia
    Queensland Brain Institute, University of Queensland, QLD 4072 Australia
    J Physiol 581:961-70. 2007
    ....
  18. pmc Distribution of IP3-mediated calcium responses and their role in nuclear signalling in rat basolateral amygdala neurons
    John M Power
    Queensland Brain Institute, The University of Queensland, St Lucia, Queensland 4072, Australia
    J Physiol 580:835-57. 2007
    ..This distribution of metabotropic-mediated store release suggests that the neuromodulatory role of metabotropic receptor stimulation in BLA-dependent learning may result from enhanced nuclear signalling...
  19. ncbi request reprint GABAergic excitation in the basolateral amygdala
    Alan R Woodruff
    Queensland Brain Institute and School of Biomedical Sciences, University of Queensland, 4072 Brisbane, Australia
    J Neurosci 26:11881-7. 2006
    ..We propose that this form of GABAergic excitation provides a means for the reliable and specific recruitment of homogeneous interneuron networks in the basal amygdala...
  20. ncbi request reprint Independent roles of calcium and voltage-dependent potassium currents in controlling spike frequency adaptation in lateral amygdala pyramidal neurons
    E S Louise Faber
    Queensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia
    Eur J Neurosci 22:1627-35. 2005
    ..This dual mechanism of controlling firing patterns is unique to lateral amygdala neurons and is likely to contribute to the very low levels of firing seen in lateral amygdala neurons in vivo...
  21. ncbi request reprint Physiological role of calcium-activated potassium currents in the rat lateral amygdala
    E S Louise Faber
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia
    J Neurosci 22:1618-28. 2002
    ..These results show that BK, SK, and non-BK SK-mediated calcium-activated potassium currents are present in principal LA neurons and play distinct physiological roles...
  22. ncbi request reprint Never fear, cannabinoids are here
    Pankaj Sah
    Nature 418:488-9. 2002
  23. ncbi request reprint Development and subunit composition of synaptic NMDA receptors in the amygdala: NR2B synapses in the adult central amygdala
    Mikel Lopez de Armentia
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra ACT 2601, Australia
    J Neurosci 23:6876-83. 2003
    ..These results show that the subunit composition synaptic NMDA receptors in the lateral and central amygdala undergo distinct developmental changes...
  24. ncbi request reprint SK channels regulate excitatory synaptic transmission and plasticity in the lateral amygdala
    E S Louise Faber
    The Queensland Brain Institute, University of Queensland, Brisbane, Queensland 4072, Australia
    Nat Neurosci 8:635-41. 2005
    ..Calcium influx through NMDARs activates SK channels and shunts the resultant excitatory postsynaptic potential. These results demonstrate a new role for SK channels as postsynaptic regulators of synaptic efficacy...
  25. ncbi request reprint Firing properties and connectivity of neurons in the rat lateral central nucleus of the amygdala
    Mikel Lopez de Armentia
    Queensland Brain Institute, University of Queensland, St Lucia, QLD 4072, Australia
    J Neurophysiol 92:1285-94. 2004
    ..The firing frequency of two of these cell types is determined by activation of SK channels. Cells receive a small input from the LA and BLA but may receive inputs that course through these nuclei en route to the CeA...
  26. ncbi request reprint Networks of parvalbumin-positive interneurons in the basolateral amygdala
    Alan R Woodruff
    Queensland Brain Institute and School of Biomedical Sciences, University of Queensland, Brisbane, Queensland 4072, Australia
    J Neurosci 27:553-63. 2007
    ..We propose that these properties allow networks of parvalbumin-expressing neurons to perform an array of information-processing tasks within the BLA...
  27. doi request reprint Behavioural neuroscience: The circuit of fear
    Pankaj Sah
    Nature 454:589-90. 2008
  28. ncbi request reprint Canonical organization of opioid modulation of nociceptive circuits. Focus on "mu opioid receptor activation inhibits GABAergic inputs to basolateral amygdala neurons through Kv1.1/Kv1.2 channels"
    Pankaj Sah
    J Neurophysiol 95:2029-30. 2006
  29. ncbi request reprint Distinct physiological mechanisms underlie altered glycinergic synaptic transmission in the murine mutants spastic, spasmodic, and oscillator
    Brett A Graham
    School of Biomedical Sciences, Faculty of Health and Hunter Medical Research Institute, The University of Newcastle, Callaghan, New South Wales 2308, Australia
    J Neurosci 26:4880-90. 2006
    ..Together, these findings show the three mutations disrupt GlyR-mediated inhibition via different physiological mechanisms, and the spastic mutation results in "compensatory" alpha1 homomeric GlyRs at extrasynaptic loci...
  30. pmc Ca2+-activated K+ (BK) channel inactivation contributes to spike broadening during repetitive firing in the rat lateral amygdala
    E S Louise Faber
    Queensland Brain Institute, University of Queensland, St Lucia, Queensland, Australia
    J Physiol 552:483-97. 2003
    ..We conclude that while inactivation of BK-type Ca2+-activated K+ channels contributes to spike broadening in lateral amygdala neurons, inactivation of another as yet unidentified outward current also plays a role...
  31. doi request reprint p75 neurotrophin receptor mediates neuronal cell death by activating GIRK channels through phosphatidylinositol 4,5-bisphosphate
    Elizabeth J Coulson
    Queensland Brain Institute and School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia
    J Neurosci 28:315-24. 2008
    ..Our results demonstrate a novel mode of activation of GIRK channels, representing an early step in the p75(NTR)-mediated cell death pathway and suggesting a function for these channels during nervous system development...
  32. ncbi request reprint Opioids inhibit lateral amygdala pyramidal neurons by enhancing a dendritic potassium current
    E S Louise Faber
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra ACT 2601, Australia
    J Neurosci 24:3031-9. 2004
    ..2 subunits, through activation of the phospholipase A(2)-arachidonic acid-lipoxygenases cascade...
  33. ncbi request reprint Sez-6 proteins affect dendritic arborization patterns and excitability of cortical pyramidal neurons
    Jenny M Gunnersen
    Brain Development Laboratory, Howard Florey Institute, The University of Melbourne, Parkville, Victoria, 3010, Australia
    Neuron 56:621-39. 2007
    ..In conclusion, cell-surface protein complexes involving Sez-6 help to sculpt the dendritic arbor, in turn enhancing synaptic connectivity...
  34. pmc Intracellular calcium store filling by an L-type calcium current in the basolateral amygdala at subthreshold membrane potentials
    John M Power
    Queensland Brain Institute, School of Biomedical Sciences, St Lucia, Queensland 4072, Australia
    J Physiol 562:439-53. 2005
    ....
  35. ncbi request reprint Functions of SK channels in central neurons
    E S Louise Faber
    Queensland Brain Institute, University of Queensland, St Lucia, Queensland, Australia
    Clin Exp Pharmacol Physiol 34:1077-83. 2007
    ..4. The present review discusses recent findings on the role of SK channels in central neurons...
  36. ncbi request reprint Calcium-activated potassium channels: multiple contributions to neuronal function
    E S Louise Faber
    Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra, Australia
    Neuroscientist 9:181-94. 2003
    ..Here the authors summarize the varieties of calcium-activated potassium channels present in central neurons and their defining molecular and biophysical properties...
  37. ncbi request reprint Inhibition and synchronization of basal amygdala principal neuron spiking by parvalbumin-positive interneurons
    Alan R Woodruff
    The Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia
    J Neurophysiol 98:2956-61. 2007
    ..We propose that these interneurons in the basal amygdala provide a potent inhibition that acts to inhibit firing of principal neurons during cortically driven oscillations...