Chris McMahon

Summary

Affiliation: Australian Centre for Sexual Health
Country: Australia

Publications

  1. ncbi request reprint Treatment of erectile dysfunction with chronic dosing of tadalafil
    Chris G McMahon
    Eur Urol 50:215-7. 2006
  2. ncbi request reprint Premature ejaculation: past, present, and future perspectives
    Chris McMahon
    Australian Centre of Sexual Health, Sydney, Australia
    J Sex Med 2:94-5. 2005
  3. ncbi request reprint Tolerance to the therapeutic effect of tadalafil does not occur during 6 months of treatment: A randomized, double-blind, placebo-controlled study in men with erectile dysfunction
    Chris G McMahon
    Australian Centre for Sexual Health, Sydney, Australia
    J Sex Med 3:504-11. 2006
  4. doi request reprint Premature ejaculation and erectile dysfunction prevalence and attitudes in the Asia-Pacific region
    C G McMahon
    Australian Centre for Sexual Health, Sydney, Australia
    J Sex Med 9:454-65. 2012
  5. pmc Premature ejaculation
    Chris G McMahon
    Australian Centre For Sexual Health Suite 2 4, Berry Road Medical Centre 1a Berry Rd St Leonards, Australia
    Indian J Urol 23:97-108. 2007
  6. doi request reprint Standard operating procedures in the disorders of orgasm and ejaculation
    Chris G McMahon
    Australian Centre for Sexual Health, Sydney, Australia
    J Sex Med 10:204-29. 2013
  7. ncbi request reprint An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation
    Chris G McMahon
    Australian Center for Sexual Health, Sydney, Australia
    BJU Int 102:338-50. 2008
  8. doi request reprint Clinical trial methodology in premature ejaculation observational, interventional, and treatment preference studies--part II--study design, outcome measures, data analysis, and reporting
    Chris G McMahon
    University of Sydney, Australian Centre for Sexual Health, St Leonards, New South Wales, Australia
    J Sex Med 5:1817-33. 2008
  9. doi request reprint Clinical trial methodology in premature ejaculation observational, interventional, and treatment preference studies--part I--defining and selecting the study population
    Chris G McMahon
    University of Sydney, Australian Centre for Sexual Health, St Leonards, New South Wales, Australia
    J Sex Med 5:1805-16. 2008
  10. doi request reprint Screening for erectile dysfunction in men with lifelong premature ejaculation--Is the Sexual Health Inventory for Men (SHIM) reliable?
    Chris G McMahon
    Australian Centre for Sexual Health, University of Sydney, Sydney, NSW, Australia
    J Sex Med 6:567-73. 2009

Detail Information

Publications32

  1. ncbi request reprint Treatment of erectile dysfunction with chronic dosing of tadalafil
    Chris G McMahon
    Eur Urol 50:215-7. 2006
  2. ncbi request reprint Premature ejaculation: past, present, and future perspectives
    Chris McMahon
    Australian Centre of Sexual Health, Sydney, Australia
    J Sex Med 2:94-5. 2005
  3. ncbi request reprint Tolerance to the therapeutic effect of tadalafil does not occur during 6 months of treatment: A randomized, double-blind, placebo-controlled study in men with erectile dysfunction
    Chris G McMahon
    Australian Centre for Sexual Health, Sydney, Australia
    J Sex Med 3:504-11. 2006
    ..Tolerance can cause a decrease in drug efficacy during chronic therapy, possibly leading to treatment failures...
  4. doi request reprint Premature ejaculation and erectile dysfunction prevalence and attitudes in the Asia-Pacific region
    C G McMahon
    Australian Centre for Sexual Health, Sydney, Australia
    J Sex Med 9:454-65. 2012
    ..Premature ejaculation (PE) is a common male sexual dysfunction. The prevalence of PE in the Asia-Pacific region has not been comprehensively studied...
  5. pmc Premature ejaculation
    Chris G McMahon
    Australian Centre For Sexual Health Suite 2 4, Berry Road Medical Centre 1a Berry Rd St Leonards, Australia
    Indian J Urol 23:97-108. 2007
    ..These drugs offer patients the convenience of on-demand dosing, significant improvements in IELT, ejaculatory control and sexual satisfaction with minimal adverse effects...
  6. doi request reprint Standard operating procedures in the disorders of orgasm and ejaculation
    Chris G McMahon
    Australian Centre for Sexual Health, Sydney, Australia
    J Sex Med 10:204-29. 2013
    ..Ejaculatory/orgasmic disorders are common male sexual dysfunctions and include premature ejaculation (PE), inhibited ejaculation, anejaculation, retrograde ejaculation, and anorgasmia...
  7. ncbi request reprint An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation
    Chris G McMahon
    Australian Center for Sexual Health, Sydney, Australia
    BJU Int 102:338-50. 2008
    ..To develop a contemporary, evidence-based definition of premature ejaculation (PE)...
  8. doi request reprint Clinical trial methodology in premature ejaculation observational, interventional, and treatment preference studies--part II--study design, outcome measures, data analysis, and reporting
    Chris G McMahon
    University of Sydney, Australian Centre for Sexual Health, St Leonards, New South Wales, Australia
    J Sex Med 5:1817-33. 2008
    ..Regulatory approval of new drug treatments for premature ejaculation (PE) demands evaluation in well-designed clinical efficacy and safety randomized clinical trials (RCTs)...
  9. doi request reprint Clinical trial methodology in premature ejaculation observational, interventional, and treatment preference studies--part I--defining and selecting the study population
    Chris G McMahon
    University of Sydney, Australian Centre for Sexual Health, St Leonards, New South Wales, Australia
    J Sex Med 5:1805-16. 2008
    ....
  10. doi request reprint Screening for erectile dysfunction in men with lifelong premature ejaculation--Is the Sexual Health Inventory for Men (SHIM) reliable?
    Chris G McMahon
    Australian Centre for Sexual Health, University of Sydney, Sydney, NSW, Australia
    J Sex Med 6:567-73. 2009
    ..Some men with premature ejaculation (PE) and normal erectile function record contradictory response/s to The Sexual Health Inventory for Men (SHIM) and may be incorrectly categorized as suffering from erectile dysfunction (ED)...
  11. doi request reprint Oral agents for the treatment of premature ejaculation: review of efficacy and safety in the context of the recent International Society for Sexual Medicine criteria for lifelong premature ejaculation
    Chris G McMahon
    Australian Centre for Sexual Health, St Leonards, NSW, Australia
    J Sex Med 8:2707-25. 2011
    ....
  12. doi request reprint Treatment of premature ejaculation in the Asia-Pacific region: results from a phase III double-blind, parallel-group study of dapoxetine
    Chris McMahon
    Australian Centre for Sexual Health, University of Sydney, NSW, Australia
    J Sex Med 7:256-68. 2010
    ..Dapoxetine is a short-acting selective serotonin reuptake inhibitor that was recently approved for the on-demand treatment of premature ejaculation (PE)...
  13. ncbi request reprint Dapoxetine for premature ejaculation
    Chris G McMahon
    Australian Centre for Sexual Health, Suite 2 4, Berry Road Medical Centre, 1a Berry Road, St Leonards, NSW 2065, Australia
    Expert Opin Pharmacother 11:1741-52. 2010
    ..Drug treatment of PE with an off-label antidepressant selective serotonin reuptake inhibitor (SSRI) drug is common. The lack of an approved drug and total reliance on off-label treatment represents a substantial unmet treatment need...
  14. doi request reprint Efficacy and safety of dapoxetine for the treatment of premature ejaculation: integrated analysis of results from five phase 3 trials
    Chris G McMahon
    Australian Centre for Sexual Health, St Leonards, New South Wales, Australia
    J Sex Med 8:524-39. 2011
    ..Dapoxetine has been evaluated for the on-demand treatment of premature ejaculation (PE) in five phase 3 studies in various populations worldwide and has recently been approved in several countries...
  15. doi request reprint An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine (ISSM) ad hoc committee for the definition of premature ejaculation
    Chris G McMahon
    Australian Center for Sexual Health, Sydney, Australia
    J Sex Med 5:1590-606. 2008
    ....
  16. ncbi request reprint Disorders of orgasm and ejaculation in men
    Chris G McMahon
    Australian Centre for Sexual Health, Sydney, Australia
    J Sex Med 1:58-65. 2004
    ..Ejaculatory/orgasmic disorders, common male sexual dysfunctions, include premature ejaculation, inhibited ejaculation, anejaculation, retrograde ejaculation and anorgasmia...
  17. ncbi request reprint Comparison of efficacy, safety, and tolerability of on-demand tadalafil and daily dosed tadalafil for the treatment of erectile dysfunction
    Chris McMahon
    Australian Centre for Sexual Health, Sydney, NSW, Australia
    J Sex Med 2:415-25; discussion 425-7. 2005
    ..To assess and compare the efficacy of on-demand tadalafil and daily tadalafil in the treatment of erectile dysfunction...
  18. ncbi request reprint The etiology and management of premature ejaculation
    Chris G McMahon
    Australian Centre for Sexual Health, Sydney, Australia
    Nat Clin Pract Urol 2:426-33. 2005
    ....
  19. ncbi request reprint Efficacy of type-5 phosphodiesterase inhibitors in the drug treatment of premature ejaculation: a systematic review
    Chris G McMahon
    Australian Centre for Sexual Health, Suite 2 4, Berry Road Medical Centre, 1a Berry Road, St Leonards, NSW, Australia 2065
    BJU Int 98:259-72. 2006
    ..Further controlled studies adhering to the contemporary consensus of ideal clinical trial design are required to clarify the role of PDE5Is in this subgroup of men with acquired PE...
  20. ncbi request reprint Vardenafil improved erectile function in a "real-life" broad population study of men with moderate to severe erectile dysfunction in Australia and New Zealand
    Chris McMahon
    Australian Centre for Sexual Health, Sydney, New South Wales, Australia
    J Sex Med 3:892-900. 2006
    ..Phosphodiesterase type 5 inhibitor drugs produce vasodilatation by inhibiting the breakdown of cyclic guanosine monophosphate and have proven efficacy in treating erectile dysfunction (ED)...
  21. ncbi request reprint A 6-month study of the efficacy and safety of tadalafil in the treatment of erectile dysfunction: a randomised, double-blind, parallel-group, placebo-controlled study in Australian men
    C G McMahon
    Australian Centre for Sexual Health, St Leonards, Sydney, New South Wales 2011, Australia
    Int J Clin Pract 59:143-9. 2005
    ..8% of placebo-treated patients. The most common treatment-emergent adverse events--headache and dyspepsia--were generally mild or moderate. Tadalafil was effective and well tolerated in Australian men with mild to severe ED...
  22. ncbi request reprint Efficacy and safety of daily tadalafil in men with erectile dysfunction previously unresponsive to on-demand tadalafil
    Chris McMahon
    Australian Centre for Sexual Health, Sydney, Australia
    J Sex Med 1:292-300. 2004
    ..To assess the efficacy and safety of daily tadalafil, a potent selective phosphodiesterase 5 inhibitor, for the treatment of erectile dysfunction (ED) in men previously unresponsive to on-demand tadalafil...
  23. ncbi request reprint Efficacy of sildenafil citrate (Viagra) in men with premature ejaculation
    Chris G McMahon
    Australian Centre for Sexual Health, Sydney, Australia
    J Sex Med 2:368-75. 2005
    ..We assessed the efficacy of sildenafil to increase the time to ejaculation, improve ejaculatory control, and decrease the postejaculatory erectile refractory time in men with PE...
  24. doi request reprint The controversial role of phosphodiesterase type 5 inhibitors in the treatment of premature ejaculation
    Emmanuele A Jannini
    Department of Experimental Medicine, University of L Aquila, Italy Australian Centre for Sexual Health, Berry Road Medical Centre, Leonards, NSW, Australia
    J Sex Med 8:2135-43. 2011
    ..It is controversial whether or not the most frequent male sexual dysfunctions, premature ejaculation (PE) and erectile dysfunction (ED), share pathogenetic mechanisms and treatments...
  25. ncbi request reprint Topiglan MacroChem
    Chris G McMahon
    Australian Center for Sexual Health, St Luke s Hospital Complex, Sydney
    Curr Opin Investig Drugs 3:602-6. 2002
    ..Further patent applications are pending in Canada, Europe and Japan [337720]. In February 2000, MacroChem filed further patent applications in 13 countries in Europe, Asia and Latin America and with the EPO [355947]...
  26. ncbi request reprint Correlates to the clinical diagnosis of premature ejaculation: results from a large observational study of men and their partners
    Raymond C Rosen
    New England Research Institutes, Watertown, Massachusetts 02472, USA
    J Urol 177:1059-64; discussion 1064. 2007
    ..In the current analysis we assessed the relative influence of those measures in identifying premature ejaculation as diagnosed by the clinician...
  27. ncbi request reprint The DSM-IV-TR definition of premature ejaculation and its impact upon the results of epidemiological studies
    Chris G McMahon
    Eur Urol 53:887-9. 2008
  28. ncbi request reprint Efficacy and safety of tadalafil for the treatment of erectile dysfunction: results of integrated analyses
    Gerald B Brock
    Department of Surgery, Division of Urology, Faculty of Medicine and Dentistry, University of Western Ontario, London, Canada
    J Urol 168:1332-6. 2002
    ..We conducted integrated analyses of the efficacy and safety of tadalafil, a potent, selective phosphodiesterase 5 inhibitor, for the treatment of erectile dysfunction...
  29. doi request reprint Are premature ejaculation symptoms curable?
    Yoram Vardi
    Department of Neuro Urology, Rambam Medical Center, Haifa, Israel
    J Sex Med 5:1546-51. 2008
    ..While premature ejaculation (PE) is the most common sexual dysfunction in men under 40, there is currently no government-approved therapy for its treatment. Is a cure possible?..
  30. ncbi request reprint Ejaculatory latency vs. patient-reported outcomes (PROs) as study end points in premature ejaculation clinical trials
    Chris G McMahon
    Eur Urol 52:321-3. 2007