Research Topics
| Chris McMahonSummaryAffiliation: Australian Centre for Sexual Health Country: Australia Publications
| Collaborators
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Detail Information
Publications
Treatment of erectile dysfunction with chronic dosing of tadalafilChris G McMahon
Eur Urol 50:215-7. 2006- Premature ejaculation: past, present, and future perspectivesChris McMahon
Australian Centre of Sexual Health, Sydney, Australia
J Sex Med 2:94-5. 2005 - Tolerance to the therapeutic effect of tadalafil does not occur during 6 months of treatment: A randomized, double-blind, placebo-controlled study in men with erectile dysfunctionChris G McMahon
Australian Centre for Sexual Health, Sydney, Australia
J Sex Med 3:504-11. 2006..Tolerance can cause a decrease in drug efficacy during chronic therapy, possibly leading to treatment failures... 
Standard operating procedures in the disorders of orgasm and ejaculationChris G McMahon
Australian Centre for Sexual Health, Sydney, Australia
J Sex Med 10:204-29. 2013..Ejaculatory/orgasmic disorders are common male sexual dysfunctions and include premature ejaculation (PE), inhibited ejaculation, anejaculation, retrograde ejaculation, and anorgasmia...- Premature ejaculation and erectile dysfunction prevalence and attitudes in the Asia-Pacific regionC G McMahon
Australian Centre for Sexual Health, Sydney, Australia
J Sex Med 9:454-65. 2012..Premature ejaculation (PE) is a common male sexual dysfunction. The prevalence of PE in the Asia-Pacific region has not been comprehensively studied... - Oral agents for the treatment of premature ejaculation: review of efficacy and safety in the context of the recent International Society for Sexual Medicine criteria for lifelong premature ejaculationChris G McMahon
Australian Centre for Sexual Health, St Leonards, NSW, Australia
J Sex Med 8:2707-25. 2011.... - Efficacy and safety of dapoxetine for the treatment of premature ejaculation: integrated analysis of results from five phase 3 trialsChris G McMahon
Australian Centre for Sexual Health, St Leonards, New South Wales, Australia
J Sex Med 8:524-39. 2011..Dapoxetine has been evaluated for the on-demand treatment of premature ejaculation (PE) in five phase 3 studies in various populations worldwide and has recently been approved in several countries... - Dapoxetine for premature ejaculationChris G McMahon
Australian Centre for Sexual Health, Suite 2 4, Berry Road Medical Centre, 1a Berry Road, St Leonards, NSW 2065, Australia
Expert Opin Pharmacother 11:1741-52. 2010..Drug treatment of PE with an off-label antidepressant selective serotonin reuptake inhibitor (SSRI) drug is common. The lack of an approved drug and total reliance on off-label treatment represents a substantial unmet treatment need... - An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine (ISSM) ad hoc committee for the definition of premature ejaculationChris G McMahon
Australian Center for Sexual Health, Sydney, Australia
J Sex Med 5:1590-606. 2008.... - An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature EjaculationChris G McMahon
Australian Center for Sexual Health, Sydney, Australia
BJU Int 102:338-50. 2008..To develop a contemporary, evidence-based definition of premature ejaculation (PE)... - Clinical trial methodology in premature ejaculation observational, interventional, and treatment preference studies--part II--study design, outcome measures, data analysis, and reportingChris G McMahon
University of Sydney, Australian Centre for Sexual Health, St Leonards, New South Wales, Australia
J Sex Med 5:1817-33. 2008..Regulatory approval of new drug treatments for premature ejaculation (PE) demands evaluation in well-designed clinical efficacy and safety randomized clinical trials (RCTs)... - Clinical trial methodology in premature ejaculation observational, interventional, and treatment preference studies--part I--defining and selecting the study populationChris G McMahon
University of Sydney, Australian Centre for Sexual Health, St Leonards, New South Wales, Australia
J Sex Med 5:1805-16. 2008.... - Treatment of premature ejaculation in the Asia-Pacific region: results from a phase III double-blind, parallel-group study of dapoxetineChris McMahon
Australian Centre for Sexual Health, University of Sydney, NSW, Australia
J Sex Med 7:256-68. 2010..Dapoxetine is a short-acting selective serotonin reuptake inhibitor that was recently approved for the on-demand treatment of premature ejaculation (PE)... - Vardenafil improved erectile function in a "real-life" broad population study of men with moderate to severe erectile dysfunction in Australia and New ZealandChris McMahon
Australian Centre for Sexual Health, Sydney, New South Wales, Australia
J Sex Med 3:892-900. 2006..Phosphodiesterase type 5 inhibitor drugs produce vasodilatation by inhibiting the breakdown of cyclic guanosine monophosphate and have proven efficacy in treating erectile dysfunction (ED)... - Efficacy of type-5 phosphodiesterase inhibitors in the drug treatment of premature ejaculation: a systematic reviewChris G McMahon
Australian Centre for Sexual Health, Suite 2 4, Berry Road Medical Centre, 1a Berry Road, St Leonards, NSW, Australia 2065
BJU Int 98:259-72. 2006..Further controlled studies adhering to the contemporary consensus of ideal clinical trial design are required to clarify the role of PDE5Is in this subgroup of men with acquired PE... - Screening for erectile dysfunction in men with lifelong premature ejaculation--Is the Sexual Health Inventory for Men (SHIM) reliable?Chris G McMahon
Australian Centre for Sexual Health, University of Sydney, Sydney, NSW, Australia
J Sex Med 6:567-73. 2009..Some men with premature ejaculation (PE) and normal erectile function record contradictory response/s to The Sexual Health Inventory for Men (SHIM) and may be incorrectly categorized as suffering from erectile dysfunction (ED)... - A 6-month study of the efficacy and safety of tadalafil in the treatment of erectile dysfunction: a randomised, double-blind, parallel-group, placebo-controlled study in Australian menC G McMahon
Australian Centre for Sexual Health, St Leonards, Sydney, New South Wales 2011, Australia
Int J Clin Pract 59:143-9. 2005..8% of placebo-treated patients. The most common treatment-emergent adverse events--headache and dyspepsia--were generally mild or moderate. Tadalafil was effective and well tolerated in Australian men with mild to severe ED... - Comparison of efficacy, safety, and tolerability of on-demand tadalafil and daily dosed tadalafil for the treatment of erectile dysfunctionChris McMahon
Australian Centre for Sexual Health, Sydney, NSW, Australia
J Sex Med 2:415-25; discussion 425-7. 2005..To assess and compare the efficacy of on-demand tadalafil and daily tadalafil in the treatment of erectile dysfunction... - Efficacy and safety of daily tadalafil in men with erectile dysfunction previously unresponsive to on-demand tadalafilChris McMahon
Australian Centre for Sexual Health, Sydney, Australia
J Sex Med 1:292-300. 2004..To assess the efficacy and safety of daily tadalafil, a potent selective phosphodiesterase 5 inhibitor, for the treatment of erectile dysfunction (ED) in men previously unresponsive to on-demand tadalafil... - Disorders of orgasm and ejaculation in menChris G McMahon
Australian Centre for Sexual Health, Sydney, Australia
J Sex Med 1:58-65. 2004..Ejaculatory/orgasmic disorders, common male sexual dysfunctions, include premature ejaculation, inhibited ejaculation, anejaculation, retrograde ejaculation and anorgasmia... - The etiology and management of premature ejaculationChris G McMahon
Australian Centre for Sexual Health, Sydney, Australia
Nat Clin Pract Urol 2:426-33. 2005.... - Efficacy of sildenafil citrate (Viagra) in men with premature ejaculationChris G McMahon
Australian Centre for Sexual Health, Sydney, Australia
J Sex Med 2:368-75. 2005.... - The controversial role of phosphodiesterase type 5 inhibitors in the treatment of premature ejaculationEmmanuele A Jannini
Department of Experimental Medicine, University of L Aquila, Italy Australian Centre for Sexual Health, Berry Road Medical Centre, Leonards, NSW, Australia
J Sex Med 8:2135-43. 2011..It is controversial whether or not the most frequent male sexual dysfunctions, premature ejaculation (PE) and erectile dysfunction (ED), share pathogenetic mechanisms and treatments... - Topiglan MacroChemChris G McMahon
Australian Center for Sexual Health, St Luke s Hospital Complex, Sydney
Curr Opin Investig Drugs 3:602-6. 2002..Further patent applications are pending in Canada, Europe and Japan [337720]. In February 2000, MacroChem filed further patent applications in 13 countries in Europe, Asia and Latin America and with the EPO [355947]... - The DSM-IV-TR definition of premature ejaculation and its impact upon the results of epidemiological studiesChris G McMahon
Eur Urol 53:887-9. 2008 - Correlates to the clinical diagnosis of premature ejaculation: results from a large observational study of men and their partnersRaymond C Rosen
New England Research Institutes, Watertown, Massachusetts 02472, USA
J Urol 177:1059-64; discussion 1064. 2007..In the current analysis we assessed the relative influence of those measures in identifying premature ejaculation as diagnosed by the clinician... - Efficacy and safety of tadalafil for the treatment of erectile dysfunction: results of integrated analysesGerald B Brock
Department of Surgery, Division of Urology, Faculty of Medicine and Dentistry, University of Western Ontario, London, Canada
J Urol 168:1332-6. 2002..Tadalafil was well tolerated, and headache and dyspepsia were the most frequent adverse events. CONCLUSIONS: Tadalafil was effective and well tolerated in this patient population... - Are premature ejaculation symptoms curable?Yoram Vardi
Department of Neuro Urology, Rambam Medical Center, Haifa, Israel
J Sex Med 5:1546-51. 2008..While premature ejaculation (PE) is the most common sexual dysfunction in men under 40, there is currently no government-approved therapy for its treatment. Is a cure possible?.. - Ejaculatory latency vs. patient-reported outcomes (PROs) as study end points in premature ejaculation clinical trialsChris G McMahon
Eur Urol 52:321-3. 2007