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Genomes and Genes | Jennifer A Marshall GravesSummaryAffiliation: Australian National University Country: Australia Publications
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Publications
Genomics. Recycling the Y chromosomeJennifer A Marshall Graves
Research School of Biological Sciences, Australian National University, Canberra, ACT 2601, Australia
Science 307:50-1. 2005
Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and developmentMarilyn B Renfree
The Australian Research Council Centre of Excellence in Kangaroo Genomics, Australia
Genome Biol 12:R81. 2011..Like other marsupials, it gives birth to highly altricial young, and has a small number of very large chromosomes, making it a valuable model for genomics, reproduction and development...
Activity map of the tammar X chromosome shows that marsupial X inactivation is incomplete and escape is stochasticShafagh Al Nadaf
Research School of Biology, The Australian National University, Biology Place, Canberra 0200, Australia
Genome Biol 11:R122. 2010..In marsupials, X inactivation is known to be paternal, incomplete and tissue-specific, and occurs in the absence of an XIST orthologue...
Marsupials and monotremes sort genome treasures from junkMatthew J Wakefield
Division of Immunology and Genetics, John Curtin School of Medical Research, The Australian National University, Canberra 0200, Australia
Genome Biol 6:218. 2005..A recent landmark paper demonstrates the unique contribution of marsupials and monotremes to comparative genome analysis, filling an evolutionary gap between the eutherian mammals (including humans) and more distant vertebrate species...
The multiple sex chromosomes of platypus and echidna are not completely identical and several share homology with the avian ZWillem Rens
Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 OES, UK
Genome Biol 8:R243. 2007..In order to investigate monotreme sex chromosome evolution, we performed a comparative study of platypus and echidna by chromosome painting and comparative gene mapping...
A first-generation integrated tammar wallaby map and its use in creating a tammar wallaby first-generation virtual genome mapChenwei Wang
Australian Research Council ARC Centre of Excellence for Kangaroo Genomics
BMC Genomics 12:422. 2011..However, only limited mapping data are available for this non-model species, comprising a physical map and a linkage map...
Evolution and comparative analysis of the MHC Class III inflammatory regionJanine E Deakin
ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 0200, Australia
BMC Genomics 7:281. 2006..We also discuss the extent of sequence conservation across the entire region and identify elements conserved in evolution...
Origin and evolution of candidate mental retardation genes on the human X chromosome (MRX)Margaret L Delbridge
Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
BMC Genomics 9:65. 2008..The human X chromosome has a biased gene content. One group of genes that is over-represented on the human X are those expressed in the brain, explaining the large number of sex-linked mental retardation (MRX) syndromes...
A second-generation anchored genetic linkage map of the tammar wallaby (Macropus eugenii)Chenwei Wang
Reprogen, Faculty of Veterinary Science, The University of Sydney, Sydney, NSW 2006, Australia
BMC Genet 12:72. 2011..It has great value as a resource to identify novel genes and for comparative studies, and is vital for the ongoing genome sequence assembly and gene ordering in this species...
ATRX has a critical and conserved role in mammalian sexual differentiationKim Huyhn
ARC Centre of Excellence for Kangaroo Genomics, Australia
BMC Dev Biol 11:39. 2011..The disease is characterised by severe mental retardation, mild alpha-thalassemia, microcephaly, short stature, facial, skeletal, genital and gonadal abnormalities...
Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammalsVidushi S Patel
The ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
BMC Biol 6:34. 2008..Here we analyse genomic data from an egg-laying monotreme mammal, the platypus (Ornithorhynchus anatinus), to explore haemoglobin evolution at the stem of the mammalian radiation...
Weird animal genomes and the evolution of vertebrate sex and sex chromosomesJennifer A Marshall Graves
Research School of Biological Science, The Australian National University, Canberra, ACT 2601, Australia
Annu Rev Genet 42:565-86. 2008..Here I explore nonmodel systems that offer some new perspectives on some venerable questions of sex and sex chromosomes...
Sex chromosome specialization and degeneration in mammalsJennifer A Marshall Graves
Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
Cell 124:901-14. 2006..The Y chromosome seems to be a product of a perverse evolutionary process that does not select the fittest Y, which may cause its degradation and ultimate extinction...
The degenerate Y chromosome--can conversion save it?Jennifer A Marshall Graves
Research School of Biological Sciences, The Australian National University, Canberra, ACT, Australia
Reprod Fertil Dev 16:527-34. 2004..Perhaps it will even speed up the decline of the Y chromosome and the onset of a new round of sex-chromosome differentiation. The struggle to preserve males may perhaps lead to hominid speciation...
Does gene dosage really matter?Jennifer A Marshall Graves
Research School of Biological Sciences, Australian National University, Canberra, ACT 2601, Australia
J Biol 6:1. 2007..However, in birds, compensation is inefficient, implying that for many genes dosage compensation is not critical, and for some genes, dosage differences have even been selected for...
Are homologies in vertebrate sex determination due to shared ancestry or to limited options?Jennifer A Marshall Graves
Research School of Biology, The Australian National University, Canberra, ACT 0200, Australia
Genome Biol 11:205. 2010..Are these systems identical by descent, or are some genes or chromosomes intrinsically better at triggering the first steps of sex determination?..
Review: Sex chromosome evolution and the expression of sex-specific genes in the placentaJ A M Graves
Research School of Biology, The Australian National University, Canberra, ACT 2601, Australia
Placenta 31:S27-32. 2010..Imprinted paternal X inactivation in rodent extraembryonic tissues would be expected to mitigate the effect of foreign paternal antigens; however, paternal inactivation seems not to occur in the human placenta...
The prion protein gene: identifying regulatory signals using marsupial sequenceMarko Premzl
Comparative Genomics Group, Research School of Biological Sciences, Australian National University, P O Box 475, Canberra, ACT 2601, Australia
Gene 349:121-34. 2005..The presence of a conserved NFAT-binding site and CPE indicates involvement of PrP(C) in signal transduction and synaptic plasticity...
In the platypus a meiotic chain of ten sex chromosomes shares genes with the bird Z and mammal X chromosomesFrank Grützner
Research School of Biological Sciences, Australian National University, GPO Box 475, Canberra, Australian Capital Territory 2601, Australia
Nature 432:913-7. 2004..This suggests an evolutionary link between mammal and bird sex chromosome systems, which were previously thought to have evolved independently...
Isolation, X location and activity of the marsupial homologue of SLC16A2, an XIST-flanking gene in eutherian mammalsEdda Koina
ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 0200, Australia
Chromosome Res 13:687-98. 2005..In male and female cells, only a single signal was found, indicating that the marsupial SLC16A2 gene is silenced on the inactivated X...
DMRT gene cluster analysis in the platypus: new insights into genomic organization and regulatory regionsNisrine El-Mogharbel
Comparative Genomics Group, Research School of Biological Sciences, Australian National University, P O Box 475, Canberra, ACT 2601, Australia
Genomics 89:10-21. 2007..The platypus DMRT1 expression pattern, and its location on an X chromosome, suggests an involvement in monotreme sexual development...
Non-homologous sex chromosomes of birds and snakes share repetitive sequencesDenis O'Meally
Research School of Biology, Australian National University, Acton, ACT 0200, Australia
Chromosome Res 18:787-800. 2010..We also establish that synteny of snake Z-linked genes has been conserved for at least 166 million years and that the snake Z consists of two conserved blocks derived from the same ancestral vertebrate chromosome...
The status of dosage compensation in the multiple X chromosomes of the platypusJanine E Deakin
Research School of Biological Sciences, The Australian National University, Canberra, Australia
PLoS Genet 4:e1000140. 2008....
Does the human X contain a third evolutionary block? Origin of genes on human Xp11 and Xq28Margaret L Delbridge
The ARC Centre of Excellence for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, ACT Australia
Genome Res 19:1350-60. 2009....
Molecular marker suggests rapid changes of sex-determining mechanisms in Australian dragon lizardsTariq Ezaz
Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, GPO Box 475, Canberra, ACT 2601, Australia
Chromosome Res 17:91-8. 2009....
Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomesFrederic Veyrunes
Research School of Biological Sciences, Australian National University, Canberra 2601, Australia
Genome Res 18:965-73. 2008..Therefore, the therian X and Y are more than 145 million years younger than previously thought...
Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammalsJulie Chaumeil
Comparative Genomics Group, Evolution Ecology and Genetics, Research School of Biology, The Australian National University, Canberra, Australian Capital Territory, Australia
PLoS ONE 6:e19040. 2011....
Core-SINE blocks comprise a large fraction of monotreme genomes; implications for vertebrate chromosome evolutionPatrick J Kirby
Comparative Genomics Group, Research School of Biological Science, The Australian National University, Canberra, ACT 2601, Australia
Chromosome Res 15:975-84. 2007..In the forthcoming sequence of the platypus genome there are still large gaps, and the extensive Mon core-SINE accumulation on the distal regions of the six large autosomal pairs may provide one explanation for this missing sequence...
The region homologous to the X-chromosome inactivation centre has been disrupted in marsupial and monotreme mammalsTimothy A Hore
ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
Chromosome Res 15:147-61. 2007..In the eutherian lineage, inserted and existing sequences provided the starting material for the non-translated RNAs of the X-inactivation centre, including XIST...
Physical map of two tammar wallaby chromosomes: a strategy for mapping in non-model mammalsJanine E Deakin
ARC Centre of Excellence for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 0200, Australia
Chromosome Res 16:1159-75. 2008..Frequent rearrangement of the X, along with the absence of a marsupial XIST gene, suggests that inactivation of the marsupial X chromosome does not depend on a whole-chromosome repression by a control locus...
Identification of cryptic sex chromosomes and isolation of X- and Y-borne genesPaul D Waters
Research School of Biological Sciences, The Australian National University, Canberra, Australia
Methods Mol Biol 422:239-51. 2008..We describe a method to isolate, identify, and map genomic BAC clones from the Y chromosome, and we also identify strategies for isolating candidate sex chromosome genes...
The evolution of epigenetic regulators CTCF and BORIS/CTCFL in amniotesTimothy A Hore
ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, Australian Capital Territory, Australia
PLoS Genet 4:e1000169. 2008....
Characterizing the chromosomes of the platypus (Ornithorhynchus anatinus)Daniel McMillan
Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
Chromosome Res 15:961-74. 2007..We have established an agreed nomenclature and identified anchor BAC clones for each chromosome that will ensure unambiguous gene localizations...
Monotreme sex chromosomes--implications for the evolution of amniote sex chromosomesPaul D Waters
Comparative Genomics Group, Research School of Biological Sciences, School of Biology, The Australian National University, GPO Box 475, Canberra, ACT 2601, Australia
Reprod Fertil Dev 21:943-51. 2009....
The ZW sex microchromosomes of an Australian dragon lizard share no homology with those of other reptiles or birdsTariq Ezaz
Institute for Applied Ecology, University of Canberra, Canberra, Australia
Chromosome Res 17:965-73. 2009..hokouensis ZW chromosomes pairs is coincidental, may be an example of convergent evolution, its status as the Z chromosome having been independently derived in birds and G. hokouensis...
Recent assembly of an imprinted domain from non-imprinted componentsRobert W Rapkins
Australian Research Council Center for Kangaroo Genomics and Research School of Biological Sciences, Australian National University, Canberra, Australia
PLoS Genet 2:e182. 2006..Thus, the evolution of imprinting in viviparous mammals is ongoing...
Autosomal location of genes from the conserved mammalian X in the platypus (Ornithorhynchus anatinus): implications for mammalian sex chromosome evolutionPaul D Waters
Comparative Genomics Group, Research Group of Biological Science, The Australian National University, Canberra, ACT, 2601, Australia
Chromosome Res 13:401-10. 2005..Since these genes lie on the X in marsupials and eutherians, and also on the homologous region of chicken chromosome 4, this represents a loss from the monotreme X rather than an additional evolutionary stratum of the human X...
Mammalian sex--Origin and evolution of the Y chromosome and SRYPaul D Waters
Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, GPO Box 475, ACT 2601, Canberra, Australia
Semin Cell Dev Biol 18:389-400. 2007..In this review we will discuss the organization and evolution of the sex chromosomes across a broad range of mammals, and speculate on how the Y chromosome, and SRY, evolved...
The monotreme genome: a patchwork of reptile, mammal and unique features?Frank Grützner
Research School of Biological Sciences, Australian National University, G P O Box 475, Canberra, Australian Capital Territory 2601, Australia
Comp Biochem Physiol A Mol Integr Physiol 136:867-81. 2003....
The X and Y chromosomes assemble into H2A.Z-containing [corrected] facultative heterochromatin [corrected] following meiosisIan K Greaves
The John Curtin School of Medical Research, The Australian National University, P O Box 334, Canberra, Australian Capital Territory, 2601 Australia
Mol Cell Biol 26:5394-405. 2006..These results provide new insights into the large-scale changes in the composition and organization of chromatin associated with spermatogenesis and argue that H2A.Z has a unique role in maintaining sex chromosomes in a repressed state...
Unravelling the evolutionary origins of X chromosome inactivation in mammals: insights from marsupials and monotremesJanine E Deakin
Comparative Genomics Group, School of Biology, College of Medicine, Biology and Environment, The Australian National University, Canberra, ACT 0200, Australia
Chromosome Res 17:671-85. 2009..Availability of sequence data, and new techniques for studying expression and chromatin modification, now make rapid advance possible...
Globin gene structure in a reptile supports the transpositional model for amniote α- and β-globin gene evolutionVidushi S Patel
Research School of Biology, The Australian National University, Canberra, ACT 0200, Australia
Chromosome Res 18:897-907. 2010..Our data from a reptile species provide further evidence to support the transpositional model for the evolution of β-globin gene cluster in amniotes...
Construction and evolution of imprinted loci in mammalsTimothy A Hore
Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
Trends Genet 23:440-8. 2007..Here, we use comparisons between different mammalian groups to chart the course of evolution of two related epigenetic regulatory systems in mammals: genomic imprinting and X-chromosome inactivation...
Characterizing the chromosomes of the Australian model marsupial Macropus eugenii (tammar wallaby)Amber E Alsop
ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
Chromosome Res 13:627-36. 2005....
A simple non-invasive protocol to establish primary cell lines from tail and toe explants for cytogenetic studies in Australian dragon lizards (Squamata: Agamidae)Tariq Ezaz
Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, GPO Box 475, Canberra, ACT, 2601, Australia
Cytotechnology 58:135-9. 2008..The method is likely to be applicable to a range of species. Such cell lines provide a virtually unlimited source of material for cytogenetic, evolutionary and genomic studies...
Specific patterns of histone marks accompany X chromosome inactivation in a marsupialEdda Koina
Research School of Biological Sciences, The Australian National University, Canberra, ACT, 0200, Australia
Chromosome Res 17:115-26. 2009..A better understanding of the epigenetic mechanisms underlying X inactivation in marsupials will provide important insights into the evolution of this complex process...
Physical mapping of the elephant X chromosome: conservation of gene order over 105 million yearsClaudia Leticia Rodríguez Delgado
Comparative Genomics Group, Research School of Biology, The Australian National University, GPO Box 475, ACT 2601, Canberra, Australia
Chromosome Res 17:917-26. 2009....
The kangaroo genome. Leaps and bounds in comparative genomicsMatthew J Wakefield
Research School of Biological Sciences, The Australian National University, Canberra, ACT 0200, Australia
EMBO Rep 4:143-7. 2003..Here we summarize the contributions from cytogenetic and genetic studies of marsupials, describe the genomic resources currently available and those being developed, and explore the benefits of a kangaroo genome project...
Origin and evolution of spermatogenesis genes on the human sex chromosomesMargaret L Delbridge
Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, Canberra ACT 2601, Australia
Soc Reprod Fertil Suppl 65:1-17. 2007..The X is more complicated - it has evolved male-advantage genes because of its representation as a single copy in males, where it is exposed to selection for male-advantage genes...
Evolution of vertebrate genes related to prion and Shadoo proteins--clues from comparative genomic analysisMarko Premzl
Computational Proteomics Group, John Curtin School of Medical Research, Australian National University, Canberra, Australia
Mol Biol Evol 21:2210-31. 2004..This provides a new framework for exploring the evolution of this unusual family of proteins and for searching for members in other fish branches and intermediate vertebrate groups...
RBMX gene is essential for brain development in zebrafishEnkhjargal Tsend-Ayush
Research School of Biological Sciences, Australian National University, Canberra, Australian Capital Territory, Australia
Dev Dyn 234:682-8. 2005..These studies demonstrate for the first time that rbmx is required for normal embryonic development, in particular of the brain, consistent with a role in X-linked mental retardation...
Relationships between vertebrate ZW and XY sex chromosome systemsTariq Ezaz
Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
Curr Biol 16:R736-43. 2006..We discuss new work from comparative genomics and cytogenetics that leads to a reconsideration of Ohno's idea and advance a new hypothesis that the mammal XY system may have arisen directly from an ancient reptile ZW system...
How did the platypus get its sex chromosome chain? A comparison of meiotic multiples and sex chromosomes in plants and animalsFrank Gruetzner
Research School of Biological Sciences, Australian National University, Canberra, ACT, 2601, Australia
Chromosoma 115:75-88. 2006....
Temperature sex reversal implies sex gene dosage in a reptileAlexander E Quinn
Institute for Applied Ecology, University of Canberra, ACT 2601, Australia
Science 316:411. 2007..Our data invite a novel hypothesis for the evolution of temperature-dependent sex determination (TSD) and suggest that sex chromosomes may exist in many TSD reptiles...
Genomic restructuring in the Tasmanian devil facial tumour: chromosome painting and gene mapping provide clues to evolution of a transmissible tumourJanine E Deakin
Research School of Biology, The Australian National University, Canberra, Australia
PLoS Genet 8:e1002483. 2012..Differences between strains are limited, reflecting the unusually stable nature of DFTD. Finally, our detailed maps of both the devil and tumour karyotypes provide a physical framework for future genomic investigations into DFTD...
The rise and fall of SRYJennifer A Marshall Graves
Research School of Biological Science, Australian National University, ACT 2601, Canberra, Australia
Trends Genet 18:259-64. 2002..At the observed rate of attrition, the human Y chromosome will be gone in 5-10 million years. This could lead to the extinction of our species or to a burst of hominid speciation...
The dragon lizard Pogona vitticeps has ZZ/ZW micro-sex chromosomesTariq Ezaz
Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, Canberra
Chromosome Res 13:763-76. 2005..Reptile microchromosomes, long dismissed as non-functional minutiae and often omitted from karyotypes, therefore deserve closer scrutiny with new and more sensitive techniques...
Molecular characterization and evolution of X and Y-borne ATRX homologues in American marsupialsDenise R Carvalho-Silva
Research School of Biological Science, Australian National University, ACT 0200, Canberra, Australia
Chromosome Res 12:795-804. 2004..Thus there appears to be a Y-borne copy of ATRY in American, as well as Australian marsupials, although it has diverged in sequence, as have other Y genes that are testis-specific in both eutherian and marsupial lineages...
Marsupial genetics and genomicsJennifer A Marshall Graves
Comparative Genomics Research Group, Research School of Biological Science, Australian National University, Canberra, ACT 2601, Australia
Trends Genet 18:517-21. 2002..We shamelessly present the case for a Kangaroo Genome Project...
A platypus' eye view of the mammalian genomeFrank Grützner
Research School of Biological Sciences, Australian National University, GPO Box 475, Canberra, Australian Capital Territory 2601, Australia
Curr Opin Genet Dev 14:642-9. 2004..Recent investigations of X-chromosome inactivation, genomic imprinting and sex chromosome evolution provide good examples of the power of the monotreme genome to inform us about mammalian genome organization and evolution...
Conservation of chromosome arrangement and position of the X in mammalian sperm suggests functional significanceIan K Greaves
Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
Chromosome Res 11:503-12. 2003....
Evolution of the testis-determining gene--the rise and fall of SRYJennifer A Marshall Graves
Research School of Biological Sciences, The Australian National University, Canberra, ACT
Novartis Found Symp 244:86-97; discussion 97-101, 203-6, 253-7. 2002..It has no central role in sex determination, and can be replaced as a trigger and lost, as have many other Y-borne genes in recent evolutionary history. The mole vole has evidently accomplished this...
An XX/XY sex microchromosome system in a freshwater turtle, Chelodina longicollis (Testudines: Chelidae) with genetic sex determinationTariq Ezaz
Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, GPO box no 475, Canberra, ACT 2601, Australia
Chromosome Res 14:139-50. 2006..This is the first time a pair of microchromosomes has been identified as the sex chromosomes in a turtle species...
Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion proteinMarko Premzl
Computational Proteomics and Therapy Design Group, Division of Biochemistry and Molecular Biology, John Curtin School of Medical Research, Australian National University, PO Box 334, ACT 2601, Canberra, Australia
Gene 314:89-102. 2003..This result together with some common structural features led to the suggestive hypothesis of a possible functional link between mammalian PrP and Sho proteins...
Characterization, chromosomal location, and genomic neighborhood of a ratite ortholog of a gene with gonadal expression in mammalsDANIEL E JANES
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA Comparative Genomics Group, Research School of Biological Sciences, Australian National University, PO Box 475, Canberra ACT 2601, Australia
Integr Comp Biol 48:505-11. 2008..Future experimentation will report the expression of SubA in ratites, other birds, and nonavian reptiles...
How the gene content of human sex chromosomes evolvedJennifer A Marshall Graves
Research School of Biological Sciences, The Australian National University, Canberra, Australia
Curr Opin Genet Dev 16:219-24. 2006..Comparisons between the gene content of the X and Y in humans, distantly related mammals, and other vertebrates, define the evolutionary past of our sex chromosomes and suggest how special selective forces act on the X and Y...
Cone visual pigments of monotremes: filling the phylogenetic gapMatthew J Wakefield
ARC, Centre for Kangaroo Genomics, Bioinformatics, The Walter and Eliza Hall Institute, Parkville, Australia
Vis Neurosci 25:257-64. 2008..So far, the echidna and platypus are the only mammals that share the gene structure of the LWS-SWS2 pigment gene complex with reptiles, birds and fishes...
The evolution of imprinting: chromosomal mapping of orthologues of mammalian imprinted domains in monotreme and marsupial mammalsCarol A Edwards
Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
BMC Evol Biol 7:157. 2007..There are several theories to account for how the mechanism evolved including the hypothesis that it was driven by the evolution of X-inactivation, or that it arose from an ancestrally imprinted chromosome...
Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complexKatherine Belov
Centre for Advanced Technologies in Animal Genetics and Reproduction, Faculty of Veterinary Science, The University of Sydney, Camden, Australia
PLoS Biol 4:e46. 2006....
Complex events in the evolution of the human pseudoautosomal region 2 (PAR2)Fadi J Charchar
Department of Genetics, La Trobe University, Bundoora, Victoria 3086, Australia
Genome Res 13:281-6. 2003..The present gene order on the human X also requires two inversions. The complicated evolutionary pathway supports the hypothesis that terminal interchromosomal rearrangements are common in regions unpaired at meiosis...
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequencesTarjei S Mikkelsen
Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA
Nature 447:167-77. 2007..A substantial proportion of these eutherian-specific CNEs arose from sequence inserted by transposable elements, pointing to transposons as a major creative force in the evolution of mammalian gene regulation...
Comparative and functional analyses of LYL1 loci establish marsupial sequences as a model for phylogenetic footprintingMichael A Chapman
Department of Haematology, Cambridge Institute for Medical Research, Cambridge University, Hills Road, Cambridge CB2 2XY, UK
Genomics 81:249-59. 2003..This study represents the first large-scale comparative analysis involving marsupial genomic sequence and demonstrates that such comparisons provide a powerful approach to characterizing mammalian regulatory elements...
Comparative analysis of ATRX, a chromatin remodeling proteinDaniel J Park
Department of Zoology, The University of Melbourne, Gate 12 Royal Parade, Melbourne 3010, Australia
Gene 339:39-48. 2004..Alignment of vertebrate ATRX sequences highlights other conserved elements, including a negatively charged mammalian sequence which we propose to be involved in binding of positively charged histone tails...
SOX9 has both conserved and novel roles in marsupial sexual differentiationAndrew J Pask
Department of Zoology, The University of Melbourne, Melbourne, Australia
Genesis 33:131-9. 2002..These previously undescribed locations of SOX9 expression suggest that SOX9 may play additional roles in the differentiation of the marsupial reproductive system...
Cone visual pigments of the Australian marsupials, the stripe-faced and fat-tailed dunnarts: sequence and inferred spectral propertiesJessica Strachan
Department of Medicine, University of Washington, Seattle, USA
Vis Neurosci 21:223-9. 2004..The MWS pigments of the two species differ by two, and UVS by three amino acid positions. No evidence was obtained for a third cone pigment in either species...
A microsatellite-based, physically anchored linkage map for the gray, short-tailed opossum (Monodelphis domestica)Paul B Samollow
Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843 4458, USA
Chromosome Res 15:269-81. 2007..54. These results greatly extend earlier findings, and provide an improved microsatellite-based linkage map for this species...
3' RACE walking along a large cDNA employing tiered suppression PCRDaniel J Park
Gate 12, Royal Parade, Dept Zoology, Melbourne University, VIC 3010, Australia
Biotechniques 34:750-2, 754-6. 2003..This robust approach represents a new tool for isolating unknown sequence under challenging cloning scenarios such as poor library representation, long coding regions, long 3' untranslated regions, and difficult template regions...
