Jennifer A Marshall Graves

Summary

Affiliation: Australian National University
Country: Australia

Publications

  1. ncbi request reprint Genomics. Recycling the Y chromosome
    Jennifer A Marshall Graves
    Research School of Biological Sciences, Australian National University, Canberra, ACT 2601, Australia
    Science 307:50-1. 2005
  2. doi request reprint How to evolve new vertebrate sex determining genes
    Jennifer A Marshall Graves
    La Trobe Institute of Molecular Science, La Trobe University, Melbourne, Victoria, Australia
    Dev Dyn 242:354-9. 2013
  3. pmc Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development
    Marilyn B Renfree
    The Australian Research Council Centre of Excellence in Kangaroo Genomics, Australia
    Genome Biol 12:R81. 2011
  4. pmc Activity map of the tammar X chromosome shows that marsupial X inactivation is incomplete and escape is stochastic
    Shafagh Al Nadaf
    Research School of Biology, The Australian National University, Biology Place, Canberra 0200, Australia
    Genome Biol 11:R122. 2010
  5. pmc Marsupials and monotremes sort genome treasures from junk
    Matthew J Wakefield
    Division of Immunology and Genetics, John Curtin School of Medical Research, The Australian National University, Canberra 0200, Australia
    Genome Biol 6:218. 2005
  6. pmc The multiple sex chromosomes of platypus and echidna are not completely identical and several share homology with the avian Z
    Willem Rens
    Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 OES, UK
    Genome Biol 8:R243. 2007
  7. pmc A first-generation integrated tammar wallaby map and its use in creating a tammar wallaby first-generation virtual genome map
    Chenwei Wang
    Australian Research Council ARC Centre of Excellence for Kangaroo Genomics
    BMC Genomics 12:422. 2011
  8. pmc Evolution and comparative analysis of the MHC Class III inflammatory region
    Janine E Deakin
    ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 0200, Australia
    BMC Genomics 7:281. 2006
  9. pmc Origin and evolution of candidate mental retardation genes on the human X chromosome (MRX)
    Margaret L Delbridge
    Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
    BMC Genomics 9:65. 2008
  10. pmc A second-generation anchored genetic linkage map of the tammar wallaby (Macropus eugenii)
    Chenwei Wang
    Reprogen, Faculty of Veterinary Science, The University of Sydney, Sydney, NSW 2006, Australia
    BMC Genet 12:72. 2011

Detail Information

Publications79

  1. ncbi request reprint Genomics. Recycling the Y chromosome
    Jennifer A Marshall Graves
    Research School of Biological Sciences, Australian National University, Canberra, ACT 2601, Australia
    Science 307:50-1. 2005
  2. doi request reprint How to evolve new vertebrate sex determining genes
    Jennifer A Marshall Graves
    La Trobe Institute of Molecular Science, La Trobe University, Melbourne, Victoria, Australia
    Dev Dyn 242:354-9. 2013
    ..Intriguingly, certain genes (such as DMRT1 and SOX3) seem to have been independently pressed into service in different ways in distantly related lineages...
  3. pmc Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development
    Marilyn B Renfree
    The Australian Research Council Centre of Excellence in Kangaroo Genomics, Australia
    Genome Biol 12:R81. 2011
    ..Like other marsupials, it gives birth to highly altricial young, and has a small number of very large chromosomes, making it a valuable model for genomics, reproduction and development...
  4. pmc Activity map of the tammar X chromosome shows that marsupial X inactivation is incomplete and escape is stochastic
    Shafagh Al Nadaf
    Research School of Biology, The Australian National University, Biology Place, Canberra 0200, Australia
    Genome Biol 11:R122. 2010
    ..In marsupials, X inactivation is known to be paternal, incomplete and tissue-specific, and occurs in the absence of an XIST orthologue...
  5. pmc Marsupials and monotremes sort genome treasures from junk
    Matthew J Wakefield
    Division of Immunology and Genetics, John Curtin School of Medical Research, The Australian National University, Canberra 0200, Australia
    Genome Biol 6:218. 2005
    ..A recent landmark paper demonstrates the unique contribution of marsupials and monotremes to comparative genome analysis, filling an evolutionary gap between the eutherian mammals (including humans) and more distant vertebrate species...
  6. pmc The multiple sex chromosomes of platypus and echidna are not completely identical and several share homology with the avian Z
    Willem Rens
    Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 OES, UK
    Genome Biol 8:R243. 2007
    ..In order to investigate monotreme sex chromosome evolution, we performed a comparative study of platypus and echidna by chromosome painting and comparative gene mapping...
  7. pmc A first-generation integrated tammar wallaby map and its use in creating a tammar wallaby first-generation virtual genome map
    Chenwei Wang
    Australian Research Council ARC Centre of Excellence for Kangaroo Genomics
    BMC Genomics 12:422. 2011
    ..However, only limited mapping data are available for this non-model species, comprising a physical map and a linkage map...
  8. pmc Evolution and comparative analysis of the MHC Class III inflammatory region
    Janine E Deakin
    ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 0200, Australia
    BMC Genomics 7:281. 2006
    ..We also discuss the extent of sequence conservation across the entire region and identify elements conserved in evolution...
  9. pmc Origin and evolution of candidate mental retardation genes on the human X chromosome (MRX)
    Margaret L Delbridge
    Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
    BMC Genomics 9:65. 2008
    ..The human X chromosome has a biased gene content. One group of genes that is over-represented on the human X are those expressed in the brain, explaining the large number of sex-linked mental retardation (MRX) syndromes...
  10. pmc A second-generation anchored genetic linkage map of the tammar wallaby (Macropus eugenii)
    Chenwei Wang
    Reprogen, Faculty of Veterinary Science, The University of Sydney, Sydney, NSW 2006, Australia
    BMC Genet 12:72. 2011
    ..It has great value as a resource to identify novel genes and for comparative studies, and is vital for the ongoing genome sequence assembly and gene ordering in this species...
  11. pmc ATRX has a critical and conserved role in mammalian sexual differentiation
    Kim Huyhn
    ARC Centre of Excellence for Kangaroo Genomics, Australia
    BMC Dev Biol 11:39. 2011
    ..The disease is characterised by severe mental retardation, mild alpha-thalassemia, microcephaly, short stature, facial, skeletal, genital and gonadal abnormalities...
  12. pmc Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals
    Vidushi S Patel
    The ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
    BMC Biol 6:34. 2008
    ..Here we analyse genomic data from an egg-laying monotreme mammal, the platypus (Ornithorhynchus anatinus), to explore haemoglobin evolution at the stem of the mammalian radiation...
  13. ncbi request reprint Sex chromosome specialization and degeneration in mammals
    Jennifer A Marshall Graves
    Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
    Cell 124:901-14. 2006
    ..The Y chromosome seems to be a product of a perverse evolutionary process that does not select the fittest Y, which may cause its degradation and ultimate extinction...
  14. doi request reprint Weird animal genomes and the evolution of vertebrate sex and sex chromosomes
    Jennifer A Marshall Graves
    Research School of Biological Science, The Australian National University, Canberra, ACT 2601, Australia
    Annu Rev Genet 42:565-86. 2008
    ..Here I explore nonmodel systems that offer some new perspectives on some venerable questions of sex and sex chromosomes...
  15. pmc Does gene dosage really matter?
    Jennifer A Marshall Graves
    Research School of Biological Sciences, Australian National University, Canberra, ACT 2601, Australia
    J Biol 6:1. 2007
    ..However, in birds, compensation is inefficient, implying that for many genes dosage compensation is not critical, and for some genes, dosage differences have even been selected for...
  16. pmc Are homologies in vertebrate sex determination due to shared ancestry or to limited options?
    Jennifer A Marshall Graves
    Research School of Biology, The Australian National University, Canberra, ACT 0200, Australia
    Genome Biol 11:205. 2010
    ..Are these systems identical by descent, or are some genes or chromosomes intrinsically better at triggering the first steps of sex determination?..
  17. ncbi request reprint The degenerate Y chromosome--can conversion save it?
    Jennifer A Marshall Graves
    Research School of Biological Sciences, The Australian National University, Canberra, ACT, Australia
    Reprod Fertil Dev 16:527-34. 2004
    ..Perhaps it will even speed up the decline of the Y chromosome and the onset of a new round of sex-chromosome differentiation. The struggle to preserve males may perhaps lead to hominid speciation...
  18. doi request reprint Review: Sex chromosome evolution and the expression of sex-specific genes in the placenta
    J A M Graves
    Research School of Biology, The Australian National University, Canberra, ACT 2601, Australia
    Placenta 31:S27-32. 2010
    ..Imprinted paternal X inactivation in rodent extraembryonic tissues would be expected to mitigate the effect of foreign paternal antigens; however, paternal inactivation seems not to occur in the human placenta...
  19. ncbi request reprint The prion protein gene: identifying regulatory signals using marsupial sequence
    Marko Premzl
    Comparative Genomics Group, Research School of Biological Sciences, Australian National University, P O Box 475, Canberra, ACT 2601, Australia
    Gene 349:121-34. 2005
    ..The presence of a conserved NFAT-binding site and CPE indicates involvement of PrP(C) in signal transduction and synaptic plasticity...
  20. ncbi request reprint In the platypus a meiotic chain of ten sex chromosomes shares genes with the bird Z and mammal X chromosomes
    Frank Grützner
    Research School of Biological Sciences, Australian National University, GPO Box 475, Canberra, Australian Capital Territory 2601, Australia
    Nature 432:913-7. 2004
    ..This suggests an evolutionary link between mammal and bird sex chromosome systems, which were previously thought to have evolved independently...
  21. pmc Isolation, X location and activity of the marsupial homologue of SLC16A2, an XIST-flanking gene in eutherian mammals
    Edda Koina
    ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 0200, Australia
    Chromosome Res 13:687-98. 2005
    ..In male and female cells, only a single signal was found, indicating that the marsupial SLC16A2 gene is silenced on the inactivated X...
  22. ncbi request reprint DMRT gene cluster analysis in the platypus: new insights into genomic organization and regulatory regions
    Nisrine El-Mogharbel
    Comparative Genomics Group, Research School of Biological Sciences, Australian National University, P O Box 475, Canberra, ACT 2601, Australia
    Genomics 89:10-21. 2007
    ..The platypus DMRT1 expression pattern, and its location on an X chromosome, suggests an involvement in monotreme sexual development...
  23. doi request reprint Non-homologous sex chromosomes of birds and snakes share repetitive sequences
    Denis O'Meally
    Research School of Biology, Australian National University, Acton, ACT 0200, Australia
    Chromosome Res 18:787-800. 2010
    ..We also establish that synteny of snake Z-linked genes has been conserved for at least 166 million years and that the snake Z consists of two conserved blocks derived from the same ancestral vertebrate chromosome...
  24. pmc Does the human X contain a third evolutionary block? Origin of genes on human Xp11 and Xq28
    Margaret L Delbridge
    The ARC Centre of Excellence for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, ACT Australia
    Genome Res 19:1350-60. 2009
    ....
  25. pmc The status of dosage compensation in the multiple X chromosomes of the platypus
    Janine E Deakin
    Research School of Biological Sciences, The Australian National University, Canberra, Australia
    PLoS Genet 4:e1000140. 2008
    ....
  26. doi request reprint Molecular marker suggests rapid changes of sex-determining mechanisms in Australian dragon lizards
    Tariq Ezaz
    Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, GPO Box 475, Canberra, ACT 2601, Australia
    Chromosome Res 17:91-8. 2009
    ....
  27. pmc Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes
    Frederic Veyrunes
    Research School of Biological Sciences, Australian National University, Canberra 2601, Australia
    Genome Res 18:965-73. 2008
    ..Therefore, the therian X and Y are more than 145 million years younger than previously thought...
  28. pmc Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammals
    Julie Chaumeil
    Comparative Genomics Group, Evolution Ecology and Genetics, Research School of Biology, The Australian National University, Canberra, Australian Capital Territory, Australia
    PLoS ONE 6:e19040. 2011
    ....
  29. ncbi request reprint The region homologous to the X-chromosome inactivation centre has been disrupted in marsupial and monotreme mammals
    Timothy A Hore
    ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
    Chromosome Res 15:147-61. 2007
    ..In the eutherian lineage, inserted and existing sequences provided the starting material for the non-translated RNAs of the X-inactivation centre, including XIST...
  30. doi request reprint Core-SINE blocks comprise a large fraction of monotreme genomes; implications for vertebrate chromosome evolution
    Patrick J Kirby
    Comparative Genomics Group, Research School of Biological Science, The Australian National University, Canberra, ACT 2601, Australia
    Chromosome Res 15:975-84. 2007
    ..In the forthcoming sequence of the platypus genome there are still large gaps, and the extensive Mon core-SINE accumulation on the distal regions of the six large autosomal pairs may provide one explanation for this missing sequence...
  31. doi request reprint Physical map of two tammar wallaby chromosomes: a strategy for mapping in non-model mammals
    Janine E Deakin
    ARC Centre of Excellence for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 0200, Australia
    Chromosome Res 16:1159-75. 2008
    ..Frequent rearrangement of the X, along with the absence of a marsupial XIST gene, suggests that inactivation of the marsupial X chromosome does not depend on a whole-chromosome repression by a control locus...
  32. doi request reprint Identification of cryptic sex chromosomes and isolation of X- and Y-borne genes
    Paul D Waters
    Research School of Biological Sciences, The Australian National University, Canberra, Australia
    Methods Mol Biol 422:239-51. 2008
    ..We describe a method to isolate, identify, and map genomic BAC clones from the Y chromosome, and we also identify strategies for isolating candidate sex chromosome genes...
  33. pmc The evolution of epigenetic regulators CTCF and BORIS/CTCFL in amniotes
    Timothy A Hore
    ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, Australian Capital Territory, Australia
    PLoS Genet 4:e1000169. 2008
    ....
  34. doi request reprint Characterizing the chromosomes of the platypus (Ornithorhynchus anatinus)
    Daniel McMillan
    Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
    Chromosome Res 15:961-74. 2007
    ..We have established an agreed nomenclature and identified anchor BAC clones for each chromosome that will ensure unambiguous gene localizations...
  35. doi request reprint Monotreme sex chromosomes--implications for the evolution of amniote sex chromosomes
    Paul D Waters
    Comparative Genomics Group, Research School of Biological Sciences, School of Biology, The Australian National University, GPO Box 475, Canberra, ACT 2601, Australia
    Reprod Fertil Dev 21:943-51. 2009
    ....
  36. doi request reprint The ZW sex microchromosomes of an Australian dragon lizard share no homology with those of other reptiles or birds
    Tariq Ezaz
    Institute for Applied Ecology, University of Canberra, Canberra, Australia
    Chromosome Res 17:965-73. 2009
    ..hokouensis ZW chromosomes pairs is coincidental, may be an example of convergent evolution, its status as the Z chromosome having been independently derived in birds and G. hokouensis...
  37. pmc Recent assembly of an imprinted domain from non-imprinted components
    Robert W Rapkins
    Australian Research Council Center for Kangaroo Genomics and Research School of Biological Sciences, Australian National University, Canberra, Australia
    PLoS Genet 2:e182. 2006
    ..Thus, the evolution of imprinting in viviparous mammals is ongoing...
  38. ncbi request reprint Autosomal location of genes from the conserved mammalian X in the platypus (Ornithorhynchus anatinus): implications for mammalian sex chromosome evolution
    Paul D Waters
    Comparative Genomics Group, Research Group of Biological Science, The Australian National University, Canberra, ACT, 2601, Australia
    Chromosome Res 13:401-10. 2005
    ..Since these genes lie on the X in marsupials and eutherians, and also on the homologous region of chicken chromosome 4, this represents a loss from the monotreme X rather than an additional evolutionary stratum of the human X...
  39. doi request reprint Unravelling the evolutionary origins of X chromosome inactivation in mammals: insights from marsupials and monotremes
    Janine E Deakin
    Comparative Genomics Group, School of Biology, College of Medicine, Biology and Environment, The Australian National University, Canberra, ACT 0200, Australia
    Chromosome Res 17:671-85. 2009
    ..Availability of sequence data, and new techniques for studying expression and chromatin modification, now make rapid advance possible...
  40. ncbi request reprint Mammalian sex--Origin and evolution of the Y chromosome and SRY
    Paul D Waters
    Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, GPO Box 475, ACT 2601, Canberra, Australia
    Semin Cell Dev Biol 18:389-400. 2007
    ..In this review we will discuss the organization and evolution of the sex chromosomes across a broad range of mammals, and speculate on how the Y chromosome, and SRY, evolved...
  41. ncbi request reprint The monotreme genome: a patchwork of reptile, mammal and unique features?
    Frank Grützner
    Research School of Biological Sciences, Australian National University, G P O Box 475, Canberra, Australian Capital Territory 2601, Australia
    Comp Biochem Physiol A Mol Integr Physiol 136:867-81. 2003
    ....
  42. pmc The X and Y chromosomes assemble into H2A.Z-containing [corrected] facultative heterochromatin [corrected] following meiosis
    Ian K Greaves
    The John Curtin School of Medical Research, The Australian National University, P O Box 334, Canberra, Australian Capital Territory, 2601 Australia
    Mol Cell Biol 26:5394-405. 2006
    ..These results provide new insights into the large-scale changes in the composition and organization of chromatin associated with spermatogenesis and argue that H2A.Z has a unique role in maintaining sex chromosomes in a repressed state...
  43. doi request reprint Globin gene structure in a reptile supports the transpositional model for amniote α- and β-globin gene evolution
    Vidushi S Patel
    Research School of Biology, The Australian National University, Canberra, ACT 0200, Australia
    Chromosome Res 18:897-907. 2010
    ..Our data from a reptile species provide further evidence to support the transpositional model for the evolution of β-globin gene cluster in amniotes...
  44. ncbi request reprint Construction and evolution of imprinted loci in mammals
    Timothy A Hore
    Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
    Trends Genet 23:440-8. 2007
    ..Here, we use comparisons between different mammalian groups to chart the course of evolution of two related epigenetic regulatory systems in mammals: genomic imprinting and X-chromosome inactivation...
  45. pmc Independent evolution of transcriptional inactivation on sex chromosomes in birds and mammals
    Alexandra M Livernois
    Evolution, Ecology and Genetics, Research School of Biology, The Australian National University, Canberra, Australian Capital Territory, Australia
    PLoS Genet 9:e1003635. 2013
    ....
  46. pmc A simple non-invasive protocol to establish primary cell lines from tail and toe explants for cytogenetic studies in Australian dragon lizards (Squamata: Agamidae)
    Tariq Ezaz
    Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, GPO Box 475, Canberra, ACT, 2601, Australia
    Cytotechnology 58:135-9. 2008
    ..The method is likely to be applicable to a range of species. Such cell lines provide a virtually unlimited source of material for cytogenetic, evolutionary and genomic studies...
  47. ncbi request reprint Characterizing the chromosomes of the Australian model marsupial Macropus eugenii (tammar wallaby)
    Amber E Alsop
    ARC Centre for Kangaroo Genomics, Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
    Chromosome Res 13:627-36. 2005
    ....
  48. doi request reprint Specific patterns of histone marks accompany X chromosome inactivation in a marsupial
    Edda Koina
    Research School of Biological Sciences, The Australian National University, Canberra, ACT, 0200, Australia
    Chromosome Res 17:115-26. 2009
    ..A better understanding of the epigenetic mechanisms underlying X inactivation in marsupials will provide important insights into the evolution of this complex process...
  49. pmc The kangaroo genome. Leaps and bounds in comparative genomics
    Matthew J Wakefield
    Research School of Biological Sciences, The Australian National University, Canberra, ACT 0200, Australia
    EMBO Rep 4:143-7. 2003
    ..Here we summarize the contributions from cytogenetic and genetic studies of marsupials, describe the genomic resources currently available and those being developed, and explore the benefits of a kangaroo genome project...
  50. doi request reprint Physical mapping of the elephant X chromosome: conservation of gene order over 105 million years
    Claudia Leticia Rodríguez Delgado
    Comparative Genomics Group, Research School of Biology, The Australian National University, GPO Box 475, ACT 2601, Canberra, Australia
    Chromosome Res 17:917-26. 2009
    ....
  51. ncbi request reprint Origin and evolution of spermatogenesis genes on the human sex chromosomes
    Margaret L Delbridge
    Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, Canberra ACT 2601, Australia
    Soc Reprod Fertil Suppl 65:1-17. 2007
    ..The X is more complicated - it has evolved male-advantage genes because of its representation as a single copy in males, where it is exposed to selection for male-advantage genes...
  52. ncbi request reprint The dragon lizard Pogona vitticeps has ZZ/ZW micro-sex chromosomes
    Tariq Ezaz
    Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, Canberra
    Chromosome Res 13:763-76. 2005
    ..Reptile microchromosomes, long dismissed as non-functional minutiae and often omitted from karyotypes, therefore deserve closer scrutiny with new and more sensitive techniques...
  53. ncbi request reprint Evolution of vertebrate genes related to prion and Shadoo proteins--clues from comparative genomic analysis
    Marko Premzl
    Computational Proteomics Group, John Curtin School of Medical Research, Australian National University, Canberra, Australia
    Mol Biol Evol 21:2210-31. 2004
    ..This provides a new framework for exploring the evolution of this unusual family of proteins and for searching for members in other fish branches and intermediate vertebrate groups...
  54. ncbi request reprint RBMX gene is essential for brain development in zebrafish
    Enkhjargal Tsend-Ayush
    Research School of Biological Sciences, Australian National University, Canberra, Australian Capital Territory, Australia
    Dev Dyn 234:682-8. 2005
    ..These studies demonstrate for the first time that rbmx is required for normal embryonic development, in particular of the brain, consistent with a role in X-linked mental retardation...
  55. ncbi request reprint How did the platypus get its sex chromosome chain? A comparison of meiotic multiples and sex chromosomes in plants and animals
    Frank Gruetzner
    Research School of Biological Sciences, Australian National University, Canberra, ACT, 2601, Australia
    Chromosoma 115:75-88. 2006
    ....
  56. ncbi request reprint Relationships between vertebrate ZW and XY sex chromosome systems
    Tariq Ezaz
    Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
    Curr Biol 16:R736-43. 2006
    ..We discuss new work from comparative genomics and cytogenetics that leads to a reconsideration of Ohno's idea and advance a new hypothesis that the mammal XY system may have arisen directly from an ancient reptile ZW system...
  57. ncbi request reprint Temperature sex reversal implies sex gene dosage in a reptile
    Alexander E Quinn
    Institute for Applied Ecology, University of Canberra, ACT 2601, Australia
    Science 316:411. 2007
    ..Our data invite a novel hypothesis for the evolution of temperature-dependent sex determination (TSD) and suggest that sex chromosomes may exist in many TSD reptiles...
  58. ncbi request reprint The rise and fall of SRY
    Jennifer A Marshall Graves
    Research School of Biological Science, Australian National University, ACT 2601, Canberra, Australia
    Trends Genet 18:259-64. 2002
    ..At the observed rate of attrition, the human Y chromosome will be gone in 5-10 million years. This could lead to the extinction of our species or to a burst of hominid speciation...
  59. pmc Genomic restructuring in the Tasmanian devil facial tumour: chromosome painting and gene mapping provide clues to evolution of a transmissible tumour
    Janine E Deakin
    Research School of Biology, The Australian National University, Canberra, Australia
    PLoS Genet 8:e1002483. 2012
    ..Differences between strains are limited, reflecting the unusually stable nature of DFTD. Finally, our detailed maps of both the devil and tumour karyotypes provide a physical framework for future genomic investigations into DFTD...
  60. ncbi request reprint A platypus' eye view of the mammalian genome
    Frank Grützner
    Research School of Biological Sciences, Australian National University, GPO Box 475, Canberra, Australian Capital Territory 2601, Australia
    Curr Opin Genet Dev 14:642-9. 2004
    ..Recent investigations of X-chromosome inactivation, genomic imprinting and sex chromosome evolution provide good examples of the power of the monotreme genome to inform us about mammalian genome organization and evolution...
  61. ncbi request reprint Marsupial genetics and genomics
    Jennifer A Marshall Graves
    Comparative Genomics Research Group, Research School of Biological Science, Australian National University, Canberra, ACT 2601, Australia
    Trends Genet 18:517-21. 2002
    ..We shamelessly present the case for a Kangaroo Genome Project...
  62. ncbi request reprint Molecular characterization and evolution of X and Y-borne ATRX homologues in American marsupials
    Denise R Carvalho-Silva
    Research School of Biological Science, Australian National University, ACT 0200, Canberra, Australia
    Chromosome Res 12:795-804. 2004
    ..Thus there appears to be a Y-borne copy of ATRY in American, as well as Australian marsupials, although it has diverged in sequence, as have other Y genes that are testis-specific in both eutherian and marsupial lineages...
  63. ncbi request reprint Conservation of chromosome arrangement and position of the X in mammalian sperm suggests functional significance
    Ian K Greaves
    Research School of Biological Sciences, The Australian National University, Canberra, ACT 2601, Australia
    Chromosome Res 11:503-12. 2003
    ....
  64. ncbi request reprint Evolution of the testis-determining gene--the rise and fall of SRY
    Jennifer A Marshall Graves
    Research School of Biological Sciences, The Australian National University, Canberra, ACT
    Novartis Found Symp 244:86-97; discussion 97-101, 203-6, 253-7. 2002
    ..It has no central role in sex determination, and can be replaced as a trigger and lost, as have many other Y-borne genes in recent evolutionary history. The mole vole has evidently accomplished this...
  65. ncbi request reprint An XX/XY sex microchromosome system in a freshwater turtle, Chelodina longicollis (Testudines: Chelidae) with genetic sex determination
    Tariq Ezaz
    Comparative Genomics Group, Research School of Biological Sciences, The Australian National University, GPO box no 475, Canberra, ACT 2601, Australia
    Chromosome Res 14:139-50. 2006
    ..This is the first time a pair of microchromosomes has been identified as the sex chromosomes in a turtle species...
  66. ncbi request reprint Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion protein
    Marko Premzl
    Computational Proteomics and Therapy Design Group, Division of Biochemistry and Molecular Biology, John Curtin School of Medical Research, Australian National University, PO Box 334, ACT 2601, Canberra, Australia
    Gene 314:89-102. 2003
    ..This result together with some common structural features led to the suggestive hypothesis of a possible functional link between mammalian PrP and Sho proteins...
  67. ncbi request reprint Characterization, chromosomal location, and genomic neighborhood of a ratite ortholog of a gene with gonadal expression in mammals
    DANIEL E JANES
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA Comparative Genomics Group, Research School of Biological Sciences, Australian National University, PO Box 475, Canberra ACT 2601, Australia
    Integr Comp Biol 48:505-11. 2008
    ..Future experimentation will report the expression of SubA in ratites, other birds, and nonavian reptiles...
  68. ncbi request reprint How the gene content of human sex chromosomes evolved
    Jennifer A Marshall Graves
    Research School of Biological Sciences, The Australian National University, Canberra, Australia
    Curr Opin Genet Dev 16:219-24. 2006
    ..Comparisons between the gene content of the X and Y in humans, distantly related mammals, and other vertebrates, define the evolutionary past of our sex chromosomes and suggest how special selective forces act on the X and Y...
  69. ncbi request reprint Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences
    Tarjei S Mikkelsen
    Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA
    Nature 447:167-77. 2007
    ..A substantial proportion of these eutherian-specific CNEs arose from sequence inserted by transposable elements, pointing to transposons as a major creative force in the evolution of mammalian gene regulation...
  70. pmc Complex events in the evolution of the human pseudoautosomal region 2 (PAR2)
    Fadi J Charchar
    Department of Genetics, La Trobe University, Bundoora, Victoria 3086, Australia
    Genome Res 13:281-6. 2003
    ..The present gene order on the human X also requires two inversions. The complicated evolutionary pathway supports the hypothesis that terminal interchromosomal rearrangements are common in regions unpaired at meiosis...
  71. ncbi request reprint Comparative and functional analyses of LYL1 loci establish marsupial sequences as a model for phylogenetic footprinting
    Michael A Chapman
    Department of Haematology, Cambridge Institute for Medical Research, Cambridge University, Hills Road, Cambridge CB2 2XY, UK
    Genomics 81:249-59. 2003
    ..This study represents the first large-scale comparative analysis involving marsupial genomic sequence and demonstrates that such comparisons provide a powerful approach to characterizing mammalian regulatory elements...
  72. pmc The evolution of imprinting: chromosomal mapping of orthologues of mammalian imprinted domains in monotreme and marsupial mammals
    Carol A Edwards
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
    BMC Evol Biol 7:157. 2007
    ..There are several theories to account for how the mechanism evolved including the hypothesis that it was driven by the evolution of X-inactivation, or that it arose from an ancestrally imprinted chromosome...
  73. pmc Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complex
    Katherine Belov
    Centre for Advanced Technologies in Animal Genetics and Reproduction, Faculty of Veterinary Science, The University of Sydney, Camden, Australia
    PLoS Biol 4:e46. 2006
    ..The opossum genome, together with other extant genomes, reveals the existence of an ancestral "immune supercomplex" that contained genes of both types of natural killer receptors together with antigen processing genes and MHC genes...
  74. doi request reprint Cone visual pigments of monotremes: filling the phylogenetic gap
    Matthew J Wakefield
    ARC, Centre for Kangaroo Genomics, Bioinformatics, The Walter and Eliza Hall Institute, Parkville, Australia
    Vis Neurosci 25:257-64. 2008
    ..So far, the echidna and platypus are the only mammals that share the gene structure of the LWS-SWS2 pigment gene complex with reptiles, birds and fishes...
  75. ncbi request reprint 3' RACE walking along a large cDNA employing tiered suppression PCR
    Daniel J Park
    Gate 12, Royal Parade, Dept Zoology, Melbourne University, VIC 3010, Australia
    Biotechniques 34:750-2, 754-6. 2003
    ..This robust approach represents a new tool for isolating unknown sequence under challenging cloning scenarios such as poor library representation, long coding regions, long 3' untranslated regions, and difficult template regions...
  76. ncbi request reprint Comparative analysis of ATRX, a chromatin remodeling protein
    Daniel J Park
    Department of Zoology, The University of Melbourne, Gate 12 Royal Parade, Melbourne 3010, Australia
    Gene 339:39-48. 2004
    ..Alignment of vertebrate ATRX sequences highlights other conserved elements, including a negatively charged mammalian sequence which we propose to be involved in binding of positively charged histone tails...
  77. ncbi request reprint SOX9 has both conserved and novel roles in marsupial sexual differentiation
    Andrew J Pask
    Department of Zoology, The University of Melbourne, Melbourne, Australia
    Genesis 33:131-9. 2002
    ..These previously undescribed locations of SOX9 expression suggest that SOX9 may play additional roles in the differentiation of the marsupial reproductive system...
  78. ncbi request reprint A microsatellite-based, physically anchored linkage map for the gray, short-tailed opossum (Monodelphis domestica)
    Paul B Samollow
    Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843 4458, USA
    Chromosome Res 15:269-81. 2007
    ..54. These results greatly extend earlier findings, and provide an improved microsatellite-based linkage map for this species...
  79. ncbi request reprint Cone visual pigments of the Australian marsupials, the stripe-faced and fat-tailed dunnarts: sequence and inferred spectral properties
    Jessica Strachan
    Department of Medicine, University of Washington, Seattle, USA
    Vis Neurosci 21:223-9. 2004
    ..The MWS pigments of the two species differ by two, and UVS by three amino acid positions. No evidence was obtained for a third cone pigment in either species...