W B Dyer

Summary

Affiliation: Australian Red Cross Blood Service
Country: Australia

Publications

  1. ncbi Correlates of antiviral immune restoration in acute and chronic HIV type 1 infection: sustained viral suppression and normalization of T cell subsets
    Wayne B Dyer
    Australian Red Cross Blood Service, Sydney, NSW 2000, Australia
    AIDS Res Hum Retroviruses 18:999-1010. 2002
  2. ncbi Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease
    Jing Qin Wu
    Retroviral Genetics Division, Center for Virus Research, Westmead Millennium Institute, University of Sydney, Darcy Road, Westmead, NSW 2145, Australia
    Retrovirology 8:18. 2011
  3. ncbi Longitudinal microarray analysis of cell surface antigens on peripheral blood mononuclear cells from HIV+ individuals on highly active antiretroviral therapy
    Jing Qin Wu
    Retroviral Genetics Division, Center for Virus Research, Westmead Millennium Institute, University of Sydney, Darcy Road, Westmead, NSW 2145, Sydney, Australia
    Retrovirology 5:24. 2008
  4. ncbi Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo
    Paul R Gorry
    Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia
    Retrovirology 4:66. 2007
  5. ncbi Antibody microarray analysis of cell surface antigens on CD4+ and CD8+ T cells from HIV+ individuals correlates with disease stages
    Jing Qin Wu
    Retroviral Genetics Division, Center for Virus Research, Westmead Millennium Institute, Darcy Road, Westmead, NSW 2145, Sydney, Australia
    Retrovirology 4:83. 2007
  6. ncbi Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection
    Wayne B Dyer
    Australian Red Cross Blood Service, 153 Clarence Street, Sydney, NSW 2000, Australia
    Retrovirology 5:112. 2008
  7. ncbi Substantial improvements in performance indicators achieved in a peripheral blood mononuclear cell cryopreservation quality assurance program using single donor samples
    Wayne B Dyer
    Australian Red Cross Blood Service, 153 Clarence Street, Sydney, NSW 2000, Australia
    Clin Vaccine Immunol 14:52-9. 2007
  8. ncbi Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1
    W B Dyer
    Australian Red Cross Blood Service NSW, Sydney, New South Wales, Australia
    J Virol 73:436-43. 1999
  9. ncbi HLA and other host factors in transfusion-acquired HIV-1 infection
    A F Geczy
    Australian Red Cross Blood Service NSW, Sydney, Australia
    Hum Immunol 61:172-6. 2000
  10. ncbi An examination of signs of disease progression in survivors of the Sydney Blood Bank Cohort (SBBC)
    M R Birch
    HIV Epidemiology Research Unit HERU, Australian Red Cross Blood Service NSW ARCBS NSW, Level 3 131 Clarence Street, Sydney, NSW 2000, Australia
    J Clin Virol 22:263-70. 2001

Detail Information

Publications23

  1. ncbi Correlates of antiviral immune restoration in acute and chronic HIV type 1 infection: sustained viral suppression and normalization of T cell subsets
    Wayne B Dyer
    Australian Red Cross Blood Service, Sydney, NSW 2000, Australia
    AIDS Res Hum Retroviruses 18:999-1010. 2002
    ..This study uniquely demonstrates that dual-PI regimens are superior in achieving these levels of virological control and immune restoration in both chronic and acute infection, compared with single-PI or non-PI regimens...
  2. ncbi Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease
    Jing Qin Wu
    Retroviral Genetics Division, Center for Virus Research, Westmead Millennium Institute, University of Sydney, Darcy Road, Westmead, NSW 2145, Australia
    Retrovirology 8:18. 2011
    ..Therefore, this work aimed to define the genomic basis of HIV interactions with the cellular transcriptome of both CD4+ and CD8+ T cells...
  3. ncbi Longitudinal microarray analysis of cell surface antigens on peripheral blood mononuclear cells from HIV+ individuals on highly active antiretroviral therapy
    Jing Qin Wu
    Retroviral Genetics Division, Center for Virus Research, Westmead Millennium Institute, University of Sydney, Darcy Road, Westmead, NSW 2145, Sydney, Australia
    Retrovirology 5:24. 2008
    ..Blood samples were collected over an average of 3 years and 5-8 time points were selected for microarray assay and statistical analysis...
  4. ncbi Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo
    Paul R Gorry
    Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia
    Retrovirology 4:66. 2007
    ....
  5. ncbi Antibody microarray analysis of cell surface antigens on CD4+ and CD8+ T cells from HIV+ individuals correlates with disease stages
    Jing Qin Wu
    Retroviral Genetics Division, Center for Virus Research, Westmead Millennium Institute, Darcy Road, Westmead, NSW 2145, Sydney, Australia
    Retrovirology 4:83. 2007
    ....
  6. ncbi Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection
    Wayne B Dyer
    Australian Red Cross Blood Service, 153 Clarence Street, Sydney, NSW 2000, Australia
    Retrovirology 5:112. 2008
    ..We examined the mechanisms that differentiated delayed progressors from LTNP in this cohort...
  7. ncbi Substantial improvements in performance indicators achieved in a peripheral blood mononuclear cell cryopreservation quality assurance program using single donor samples
    Wayne B Dyer
    Australian Red Cross Blood Service, 153 Clarence Street, Sydney, NSW 2000, Australia
    Clin Vaccine Immunol 14:52-9. 2007
    ....
  8. ncbi Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1
    W B Dyer
    Australian Red Cross Blood Service NSW, Sydney, New South Wales, Australia
    J Virol 73:436-43. 1999
    ..High levels of circulating effector and memory HIV-specific CTLs can be maintained for prolonged periods in these patients despite very low viral loads...
  9. ncbi HLA and other host factors in transfusion-acquired HIV-1 infection
    A F Geczy
    Australian Red Cross Blood Service NSW, Sydney, Australia
    Hum Immunol 61:172-6. 2000
    ....
  10. ncbi An examination of signs of disease progression in survivors of the Sydney Blood Bank Cohort (SBBC)
    M R Birch
    HIV Epidemiology Research Unit HERU, Australian Red Cross Blood Service NSW ARCBS NSW, Level 3 131 Clarence Street, Sydney, NSW 2000, Australia
    J Clin Virol 22:263-70. 2001
    ..In contrast, in the SA cohort, comparison study group for the SBBC, five of 24 remain therapy naïve after 15 years infection with HIV-1 and all have detectable VL...
  11. ncbi Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort
    J C Learmont
    Australian Red Cross Blood Service New South Wales, Sydney
    N Engl J Med 340:1715-22. 1999
    ..We present longitudinal immunologic and virologic data on the six surviving members and one deceased member of this cohort through September 30, 1998...
  12. ncbi Influence of FcgammaRIIA and MBL polymorphisms on severe acute respiratory syndrome
    F F Yuan
    Australian Red Cross Blood Service Endeavour, Sydney, NSW, Australia
    Tissue Antigens 66:291-6. 2005
    ..The study reveals that in addition to age and co-morbidity, FcgammaRIIA polymorphism of individuals may also influence outcome after infection with the SARS-Cov...
  13. ncbi Genetic analyses reveal structured HIV-1 populations in serially sampled T lymphocytes of patients receiving HAART
    Simon J Potter
    Retroviral Genetics Laboratory, Center for Virus Research, Westmead Millennium Institute, Westmead Hospital, The University of Sydney, Darcy Road, Westmead, Sydney NSW 2145, Australia
    Virology 348:35-46. 2006
    ....
  14. ncbi First demonstration of a lack of viral sequence evolution in a nonprogressor, defining replication-incompetent HIV-1 infection
    Bin Wang
    Retroviral Genetics Laboratory, Center for Virus Research, Westmead Millennium Institute, Westmead, NSW 2145, Australia
    Virology 312:135-50. 2003
    ..Further study on the antigenic properties of this strain may assist in the development of HIV vaccines and therapeutics...
  15. ncbi Drug resistance and viral evolution in plasma and peripheral blood cells during structured treatment interruption (STI) and non-interrupted HAART
    Yuan Min Wang
    Retroviral Genetics Laboratory, Centre for Virus Research, Westmead Millennium Institutes, Westmead Hospital, The University of Sydney, Sydney, Australia
    Curr HIV Res 5:235-50. 2007
    ..In addition, little remains known how viral evolutionary process may differ between cell-free and cell-associated compartments, over time, in vivo in patients receiving HAART or STI...
  16. ncbi Transcriptional profiles in CD8+ T cells from HIV+ progressors on HAART are characterized by coordinated up-regulation of oxidative phosphorylation enzymes and interferon responses
    Jing Qin Wu
    Retroviral Genetics Division, Center for Virus Research, Westmead Millennium Institute, University of Sydney, Westmead, NSW, Australia
    Virology 380:124-35. 2008
    ..These results will provide biological insights into natural control of HIV versus HIV control under HAART...
  17. ncbi High prevalence of the CD14-159CC genotype in patients infected with severe acute respiratory syndrome-associated coronavirus
    Fang F Yuan
    Cell Biology Laboratory, ARCBS Endeavour, 153 Clarence Street, Sydney, NSW 2000, Australia
    Clin Vaccine Immunol 14:1644-5. 2007
    ..029; odds ratio, 2.74; 95% confidence interval, 1.15 to 6.57; controls, P = 0.04; odds ratio, 2.41; 95% confidence interval, 1.05 to 5.54), and both CD14-159CC and FcgammaRIIA-RR131 are risk genotypes for severe SARS-CoV infection...
  18. ncbi High frequency of nonprogression 20 years after transfusion-transmitted human immunodeficiency virus type-1 infection
    Wayne B Dyer
    Transfusion 44:1397-8. 2004
  19. ncbi Evidence for predominance of CCR5-using HIV-1 strains during highly active antiretroviral therapy
    Yuan Min Wang
    Retroviral Genetics Division, Center for Virus Research, Westmead Millennium Institute, Westmead Hospital, University of Sydney, Sydney, Australia
    Curr HIV Res 5:221-34. 2007
    ....
  20. ncbi Replication-dependent pathogenicity of attenuated nef-deleted HIV-1 in vivo
    Paul R Gorry
    Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia
    J Acquir Immune Defic Syndr 46:390-4. 2007
    ..We report the outcome of a 26-year prospective study documenting the clinical course of nef-deleted HIV-1 infection in 7 SBBC members...
  21. ncbi Identification of circulating antigen-specific CD4+ T lymphocytes with a CCR5+, cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection
    John J Zaunders
    Centre for Immunology, St Vincent s Hospital, and University of New South Wales, Sydney, Australia
    Blood 103:2238-47. 2004
    ..Moreover, expression of CCR5 may render them particularly susceptible to cytopathic effects during progressive HIV-1 infection...
  22. ncbi Comprehensive analyses of a unique HIV-1-infected nonprogressor reveal a complex association of immunobiological mechanisms in the context of replication-incompetent infection
    Bin Wang
    Retroviral Genetics Laboratory, Centre for Virus Research, Westmead Millennium Institute, Westmead Hospital, University of Sydney, Westmead, New South Wales 2145, Australia
    Virology 304:246-64. 2002
    ..Understanding how to induce these protective immune responses in other individuals could provide a major step forward in the design of effective immunotherapies or vaccines against HIV infection...
  23. ncbi CD127+CCR5+CD38+++ CD4+ Th1 effector cells are an early component of the primary immune response to vaccinia virus and precede development of interleukin-2+ memory CD4+ T cells
    John J Zaunders
    Centre for Immunology, St Vincent s Hospital, Victoria Street, Darlinghurst, NSW 2010, Australia
    J Virol 80:10151-61. 2006
    ..The current study provides important information on the differentiation of IL-2+ vaccinia virus-specific memory cells, allowing further study of antiviral effector CD4+ T cells in healthy adults and their dysfunction in HIV-1 infection...