Research Topics
Genomes and Genes | S E BartlettSummaryAffiliation: Australian National University Country: Australia Publications
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Publications
Protein tyrosine kinase inhibitors synergize with nerve growth factor in embryonic chick sensory neuronal cell survivalS E Bartlett
Developmental Neurobiology, Division of Neuroscience, The John Curtin School of Medical Research, Australian National University, Canberra, ACT
Neurosci Lett 227:87-90. 1997..Therefore it will be important to determine if herbimycin can be used as a therapeutic agent for enhancing nerve regeneration following injury...
PtdIns 4-kinasebeta and neuronal calcium sensor-1 co-localize but may not directly associate in mammalian neuronsS E Bartlett
Division of Neuroscience, The John Curtin School of Medical Research, Australian National University, Canberra, Australia
J Neurosci Res 62:216-24. 2000..We then provide biochemical evidence that PtdIns 4-kinasebeta may not be in physical association with NCS-1 in mammalian nervous tissue unlike that previously reported in yeast...
Development and characterization of human and mouse specific antibodies to CuZn-superoxide dismutase (SOD1)S E Bartlett
Department of Physiology and Pharmacology, The University of Queensland, St Lucia, QLD 4072, Brisbane, Australia
J Neurosci Methods 98:63-7. 2000..As SOD1 exists as a homodimeric complex in the cytoplasm of cells, this suggests that amino acids in position, 25-37 are close to the dimeric interface of SOD1...
Differential mRNA expression and subcellular locations of PI3-kinase isoforms in sympathetic and sensory neuronsS E Bartlett
Developmental Neurobiology, Division of Neuroscience, The John Curtin School of Medical Research, Australian National University, Canberra, ACT
J Neurosci Res 56:44-53. 1999..In addition, unlike other cell types, wortmannin has little effect on actin filament polymerization in either mouse cultured SCG or DRG neurons...
In sympathetic but not sensory neurones, phosphoinositide-3 kinase is important for NGF-dependent survival and the retrograde transport of 125I-betaNGFS E Bartlett
Developmental Neurobiology, John Curtin School of Medical Research, Australian National University, Canberra
Brain Res 761:257-62. 1997....
Transport of endosomal early antigen 1 in the rat sciatic nerve and location in cultured neuronsS E Bartlett
Division of Neuroscience, The John Curtin School of Medical Research, Australian National University, Canberra, ACT
Neuroreport 12:281-4. 2001..This suggests that EEA1 is transported in the anterograde direction in axons either as part of the homeostatic process or to the nerve ligation site in response to nerve injury...
Deletion of guanine nucleotide binding protein alpha z subunit in mice induces a gene dose dependent tolerance to morphineK J Leck
Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra, ACT 0200, Australia
Neuropharmacology 46:836-46. 2004..The results suggest that G(z) signaling pathways are involved in transducing the analgesic and lethality effects of morphine following chronic morphine treatment...
Alterations in ciliary neurotrophic factor signaling in rapsyn deficient miceS E Bartlett
Department of Physiology and Pharmacology, The University of Queensland, St. Lucia, Brisbane, Queensland, Australia
J Neurosci Res 64:575-81. 2001..This alteration may in part, account for the increased muscle nerve branching and motoneuron survival seen in rapsyn deficient mice...
Signalling events regulating the retrograde axonal transport of 125I-beta nerve growth factor in vivoA J Reynolds
Developmental Neurobiology, Division of Neuroscience, The John Curtin School of Medical Research, Australian National University, GPO Box 334, Canberra, ACT 2601, Australia
Brain Res 798:67-74. 1998..Potentially, these isoforms could activate alternative signalling pathways, such as pp70S6K in sensory neurons...
Molecular mechanisms regulating the retrograde axonal transport of neurotrophinsA J Reynolds
Division of Neuroscience, John Curtin School of Medical Research, Australian National University, GPO Box 334, ACT 2601, Canberra, Australia
Brain Res Brain Res Rev 33:169-78. 2000....
Promotion of motoneuron survival and branching in rapsyn-deficient miceG B Banks
Department of Physiology and Pharmacology, University of Queensland, St Lucia, Queensland 4072, Australia
J Comp Neurol 429:156-65. 2001..Moreover, these results support the idea that skeletal muscle activity through effective synaptic transmission and intramuscular axonal branching are major mechanisms that regulate motoneuron survival during development...
The distribution of neuronal calcium sensor-1 protein in the developing and adult rat retinaA J Reynolds
Division of Neuroscience, John Curtin School of Medical Research, Canberra ACT, Australia
Neuroreport 12:725-8. 2001..These findings suggest that NCS-1 plays a role in synaptogenesis in the retina and in synaptic transmission at conventional synapses but not ribbon synapses in the adult rat retina...
Anterograde and retrograde transport of active extracellular signal-related kinase 1 (ERK1) in the ligated rat sciatic nerveA J Reynolds
Division of Neuroscience, The John Curtin School of Medical Resarch, Australian National University, Canberra
Neuroscience 105:761-71. 2001..Taken together our results suggest that a component of the accumulation of active ERK1 on the distal and proximal side of the nerve ligations results from transport in the anterograde and retrograde direction in the rat sciatic nerve...
Hypertolerance to morphine in G(z alpha)-deficient miceI A Hendry
Division of Neuroscience, John Curtin School of Medical Research, Australian National University, GPO Box 334, ACT 2601, Canberra, Australia
Brain Res 870:10-9. 2000..Our results suggest that the presence of G(z alpha) delays the development of morphine tolerance and represents a possible therapeutic target for improving the clinical use of morphine...
