Wy Au

Summary

Publications

  1. doi request reprint Oral arsenic trioxide for relapsed acute promyelocytic leukemia in pediatric patients
    Wing Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong, China
    Pediatr Blood Cancer 58:630-2. 2012
  2. pmc Multi-center transferability of a breath-hold T2 technique for myocardial iron assessment
    Taigang He
    National Heart and Lung Institute, Imperial College London, UK
    J Cardiovasc Magn Reson 10:11. 2008
  3. ncbi request reprint Autoimmune thyroid dysfunction after hematopoietic stem cell transplantation
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Bone Marrow Transplant 35:383-8. 2005
  4. ncbi request reprint Imatinib mesylate (STI-571) and porphyria cutanea tarda in a Chinese patient
    W Y Au
    Department of Medicine, Division of Clinical Biochemistry, Queen Mary Hospital, Hong Kong
    Haematologica 90:ECR18. 2005
  5. ncbi request reprint Incidence and spectrum of non-Hodgkin lymphoma in Chinese migrants to British Columbia
    W Y Au
    Department of Medical Oncology, British Columbia Cancer Agency and the University of British Columbia
    Br J Haematol 128:792-6. 2005
  6. ncbi request reprint Molecular epidemiology of follicular lymphoma in Chinese: relationship with bcl-2/IgH translocation and bcl-6 397G/C polymorphism
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, People s Republic of China
    Ann Hematol 84:506-9. 2005
  7. ncbi request reprint Hyperbilirubinemia and cholelithiasis in Chinese patients with hemoglobin H disease
    W Y Au
    Department of Medicine, Queen Mary Hospital, Pokfulam Road, Hong Kong, China
    Ann Hematol 84:671-4. 2005
  8. ncbi request reprint Massive haemolysis because of Clostridium perfringens [corrected] liver abscess in a patient on peritoneal dialysis
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, China
    Br J Haematol 131:2. 2005
  9. ncbi request reprint Hepatitis C virus infection in adult Chinese hemophilia patients negative for the human immunodeficiency virus: treatment results with interferon and ribavirin
    Wing Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Int J Hematol 82:259-61. 2005
  10. ncbi request reprint Nontuberculous mycobacterial infections in Chinese hematopoietic stem cell transplantation recipients
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Bone Marrow Transplant 32:709-14. 2003

Detail Information

Publications102 found, 100 shown here

  1. doi request reprint Oral arsenic trioxide for relapsed acute promyelocytic leukemia in pediatric patients
    Wing Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong, China
    Pediatr Blood Cancer 58:630-2. 2012
    ..Oral As(2) O(3) , particularly in prolonged maintenance with oral ATRA may obviate the need of stem cell transplantation in relapsed pediatric APL...
  2. pmc Multi-center transferability of a breath-hold T2 technique for myocardial iron assessment
    Taigang He
    National Heart and Lung Institute, Imperial College London, UK
    J Cardiovasc Magn Reson 10:11. 2008
    ..This cardiac T2 technique has good interstudy reproducibility, but its transferability to different centres has not yet been investigated...
  3. ncbi request reprint Autoimmune thyroid dysfunction after hematopoietic stem cell transplantation
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Bone Marrow Transplant 35:383-8. 2005
    ..Owing to the small number of reported cases and different HLA associations with AITD in different populations, our observations await confirmatory data from other registries...
  4. ncbi request reprint Imatinib mesylate (STI-571) and porphyria cutanea tarda in a Chinese patient
    W Y Au
    Department of Medicine, Division of Clinical Biochemistry, Queen Mary Hospital, Hong Kong
    Haematologica 90:ECR18. 2005
  5. ncbi request reprint Incidence and spectrum of non-Hodgkin lymphoma in Chinese migrants to British Columbia
    W Y Au
    Department of Medical Oncology, British Columbia Cancer Agency and the University of British Columbia
    Br J Haematol 128:792-6. 2005
    ..Genetic factors appeared to be stronger than environmental factors in governing the overall incidence of NHL in Chinese. However, certain subtypes of lymphoma may show decreased rates in migrants because of environmental factors...
  6. ncbi request reprint Molecular epidemiology of follicular lymphoma in Chinese: relationship with bcl-2/IgH translocation and bcl-6 397G/C polymorphism
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, People s Republic of China
    Ann Hematol 84:506-9. 2005
    ..The reasons for the lower incidence of FL in Chinese remain unanswered...
  7. ncbi request reprint Hyperbilirubinemia and cholelithiasis in Chinese patients with hemoglobin H disease
    W Y Au
    Department of Medicine, Queen Mary Hospital, Pokfulam Road, Hong Kong, China
    Ann Hematol 84:671-4. 2005
    ..2%), but not heterozgyotes (42.2%), were found to have a significantly increased risk of gallstones and jaundice. However, common Chinese Gilbert syndrome alleles do not completely explain the variable risks...
  8. ncbi request reprint Massive haemolysis because of Clostridium perfringens [corrected] liver abscess in a patient on peritoneal dialysis
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, China
    Br J Haematol 131:2. 2005
  9. ncbi request reprint Hepatitis C virus infection in adult Chinese hemophilia patients negative for the human immunodeficiency virus: treatment results with interferon and ribavirin
    Wing Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Int J Hematol 82:259-61. 2005
    ..A sustained response occurred in 50% of the patients completing treatment and occurred only in patients with genotypes 1, 3, and 6 but not with quasi species...
  10. ncbi request reprint Nontuberculous mycobacterial infections in Chinese hematopoietic stem cell transplantation recipients
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Bone Marrow Transplant 32:709-14. 2003
    ..NTM isolation is a marker for severe immunosuppression and poor prognosis. When there is doubt over species identity or extent of infection, broad-spectrum cover may be prudent...
  11. ncbi request reprint Potential role for platelet apheresis for post-liver transplant thrombocytosis complicating portal vein thrombosis
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China
    J Clin Apher 19:192-6. 2004
    ..The use of cell separation procedures may be a relatively rapid, reversible, and reasonably safe way to control platelet counts peri-operatively in liver transplant recipients...
  12. ncbi request reprint Autologous stem cell transplantation for nasal NK/T-cell lymphoma: a progress report on its value
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong, People s Republic of China
    Ann Oncol 14:1673-6. 2003
    ..For patients with relapsed, refractory or extranasal disease, early consideration for allogeneic transplantation and alternative therapy may be warranted...
  13. ncbi request reprint Disseminated zoster, hyponatraemia, severe abdominal pain and leukaemia relapse: recognition of a new clinical quartet after bone marrow transplantation
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Pokfulam Road, Hong Kong SAR, China
    Br J Dermatol 149:862-5. 2003
    ..Prompt treatment of leukaemia relapse also resulted in complete remission. A possible immunological link between concurrent breakdown of immune control of VZV and leukaemia is discussed...
  14. ncbi request reprint Hodgkin's lymphoma in Chinese migrants to British Columbia: a 25-year survey
    W Y Au
    Department of Medical Oncology, British Columbia Cancer Agency and the University of British Columbia, Vancouver, BC, Canada
    Ann Oncol 15:626-30. 2004
    ..Compared with the West, Hodgkin's lymphoma in Oriental countries is characterized by a lower incidence rate and a higher proportion of mixed cellularity histology. Both environmental and genetic factors may be involved...
  15. ncbi request reprint Living donor liver transplantation for hepatitis C related hepatocellular carcinoma in a haemophilia A patient
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China
    Haemophilia 11:405-7. 2005
    ..Careful patient and donor choice, meticulous surgical expertise and proper counselling, however, are prudent requirements...
  16. ncbi request reprint The spectrum of lymphoma with 8q24 aberrations: a clinical, pathological and cytogenetic study of 87 consecutive cases
    Wing Y Au
    Department of Medical Oncology, British Columbia Cancer Agency, Vancouver, Canada
    Leuk Lymphoma 45:519-28. 2004
    ..We conclude that the finding of an 8q24 aberration is of marked negative prognostic significance, either at diagnosis or at disease progression, in a variety of NHL...
  17. ncbi request reprint Chronic myeloid leukemia in an adolescent with Ollier's disease after intensive X-ray exposure
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, SAR, China
    Leuk Lymphoma 45:613-6. 2004
    ....
  18. ncbi request reprint Vitiligo as a paraneoplastic syndrome preceding pituitary adenoma and subsequent acute lymphoblastic leukemia
    Wing Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Leuk Lymphoma 45:1683-5. 2004
    ..He subsequently died of acute lymphoblastic leukemia after pituitary radiation. The possible pathological associations between the 2 malignancies and vitiligo are discussed...
  19. ncbi request reprint Life-threatening cryoglobulinemia in HCV-negative Southern Chinese and a novel association with structural aortic abnormalities
    Wing Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong, China
    Ann Hematol 84:95-8. 2005
    ..The association of aortic abnormality and cryoglobulinemia is hitherto unreported and may be peculiar to our ethnic group. Aggressive control of the cryoglobulin may help to reduce aortic intima damage...
  20. ncbi request reprint Cerebellar degeneration and folate deficiency due to cough mixture abuse
    W Y Au
    Department of Medicine and Clinical Biochemistry Unit, Queen Mary Hospital, University of Hong Kong
    Haematologica 90:ECR28. 2005
  21. ncbi request reprint Toxoplasma gondii serology and stem cell transplantation in Chinese
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong, China
    Transplant Proc 37:4497-9. 2005
    ..We concluded that in low incidence areas, toxoplasmosis is not a significant complication of HSCT with septrin prophylaxis. Most patients are also expected to remain seronegative after HSCT...
  22. ncbi request reprint A synopsis of current care of thalassaemia major patients in Hong Kong
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Hong Kong Med J 17:261-6. 2011
    ..To provide a synopsis of current thalassaemia major patient care in Hong Kong...
  23. ncbi request reprint A synopsis of current haemophilia care in Hong Kong
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Hong Kong Med J 17:189-94. 2011
    ..To provide a synopsis of current haemophilia care in Hong Kong...
  24. ncbi request reprint Current management of nasal NK/T-cell lymphoma
    Wing Y Au
    Department of Medicine, University Medical Unit, Queen Mary Hospital, Hong Kong
    Oncology (Williston Park) 24:352-8. 2010
    ..For disseminated and refractory cases, the 5-year survival rate is below 10%, and better methods of treatment are needed...
  25. doi request reprint A unique case of B cell lymphoma relapsing as CD4/CD56 blastic neoplasm
    Wing Y Au
    Department of Medicine, Queen Mary Hospital, Pokfulam, Hong Kong
    Leuk Lymphoma 50:932-6. 2009
    ..Our case illustrated the potential pitfalls and ambiguity of lineage classification based on morphology and immunophenotyping alone, especially for rare and poorly defined entities...
  26. ncbi request reprint Glucose-6-phosphate-dehydrogenase deficiency and haematopoietic stem cell transplantation in Chinese patients
    W Y Au
    Department of Medicine, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Hong Kong Med J 15:35-8. 2009
    ..This can result in unexpected significant G6PD deficiency. Hence, a repeat G6PD screening at stable engraftment is recommended, especially before commencement of oxidative medications...
  27. doi request reprint Organ-specific hemosiderosis and functional correlation in Chinese patients with thalassemia intermedia and hemoglobin H disease
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong, Hong Kong
    Ann Hematol 88:947-50. 2009
    ..Prospective data with serial functional and imaging monitoring is needed to verify the utility for chelation to improve cardiac and endocrine function in this group of patients...
  28. doi request reprint Penile lichen sclerosus after allogeneic stem cell transplantation
    W Y Au
    Department of Medicine, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Br J Dermatol 159:470-2. 2008
    ..These cases add further evidence to support the notion that penile lichen sclerosus should be included within the expanding sclerodermoid spectrum of late-stage cutaneous chronic GVHD...
  29. ncbi request reprint A pilot MRI study of organ specific hemosiderosis and functional correlation in Chinese patients with myelodysplasia and aplastic anemia with raised ferritin levels
    Wy Au
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Hematol Oncol 26:225-8. 2008
    ..Hence, chelating agents may still have a role to improve organ function. Prospective data with serial functional and imaging monitoring is needed...
  30. doi request reprint Isolated gingival relapse of acute lymphoblastic leukemia after transplantation
    Wing Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong
    J Oral Pathol Med 37:249-51. 2008
    ..Examinations of the peripheral blood and marrow were normal. Molecular studies confirmed clonal relationship between the gum lesion with the original marrow disease, despite the anatomical, histological and chronological separations...
  31. doi request reprint A T2* magnetic resonance imaging study of pancreatic iron overload in thalassemia major
    Wing Yan Au
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, China
    Haematologica 93:116-9. 2008
    ..This suggested that improved chelation may improve beta cell reserve and prevent pancreatic atrophy...
  32. ncbi request reprint A magnetic resonance imaging study of iron overload in hemopoietic stem cell transplant recipients with increased ferritin levels
    W Y Au
    University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    Transplant Proc 39:3369-74. 2007
    ..We concluded that iron overload may contribute to organ damage after HSCT, and MRI assessment may be useful in its detection and treatment monitoring...
  33. ncbi request reprint HLA associations, microsatellite instability and epigenetic changes in thyroid lymphoma in Chinese
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong, SAR China
    Leuk Lymphoma 48:531-4. 2007
    ..MSI was absent, but aberrant promoter methylation was found in both thyroid MZL and DLCL and p73 methylation was unexpectedly common...
  34. ncbi request reprint Tumor necrosis factor alpha promoter polymorphism and the risk of chronic lymphocytic leukemia and myeloma in the Chinese population
    W Y Au
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Leuk Lymphoma 47:2189-93. 2006
    ..These argue for a possible biological role for increased TNFalpha production in CLL progression in low-risk individuals...
  35. ncbi request reprint Serial analysis of JAK2 mutation in a patient who developed essential thrombocythemia after orthotopic liver transplantation
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Am J Hematol 81:880-2. 2006
    ..Thrombocythemia became obvious after OLT. The patient subsequently developed blastic transformation 12 months afterward, a process probably accelerated by the immunosuppression required for the OLT...
  36. ncbi request reprint Senile EBER positive diffuse large B cell lymphoma relapsing in the nasopharynx
    Wing Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong
    Haematologica 91:ECR41. 2006
  37. ncbi request reprint A prospective study of respiratory ciliary structure and function after stem cell transplantation
    W Y Au
    University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
    Bone Marrow Transplant 38:243-8. 2006
    ..We conclude that structural and functional ciliary abnormalities are common in recipients of HSCT, and predict post-HSCT deterioration. However, there is no evidence to show that CBF monitoring may be of prospective benefit...
  38. ncbi request reprint Challenges and pitfalls in prenatal screening in pregnancies involving allogeneic stem cell transplantation recipients
    W Y Au
    Bone Marrow Transplant Unit, Department of Medicine, Queen Mary Hospital, Hong Kong
    Bone Marrow Transplant 39:379-82. 2007
    ..Good communication between obstetricians and the HSCT physician is paramount to promote successful pregnancies in this distinct patient population...
  39. ncbi request reprint Generalized vitiligo after lymphocyte infusion for relapsed leukaemia
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong
    Br J Dermatol 145:1015-7. 2001
    ..The specific destruction of melanocytes in both patients was therefore probably mediated by new alloreactive lymphocytes infused from the donors...
  40. ncbi request reprint Two cases of therapy-related acute promyelocytic leukemia (t-APL) after mantle cell lymphoma and gestational trophoblastic disease
    W Y Au
    University Department of Medicine, Professorial Block, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Ann Hematol 81:659-61. 2002
    ..For patients with a history of active malignancy and heavy previous chemotherapy exposure, the use of nontoxic arsenic therapy appeared to be effective and prudent...
  41. ncbi request reprint Speechless after bone marrow transplantation: a rare complication of parainfluenza virus related group in an adult
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, China
    Leuk Lymphoma 43:421-2. 2002
    ..Our case illustrated that the virulence of some URT viral infections depend on host immune factors, and may remain latent until graft versus host responses can be mounted...
  42. ncbi request reprint Subvalvular pulmonary stenosis, demyelination and myelodysplasia with monosomy 7
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong, People s Republic of China
    Leuk Lymphoma 43:1505-7. 2002
    ..The importance of recognition of rare clinical syndromes that may predispose to leukemia is discussed...
  43. ncbi request reprint Post-transplantation lymphoproliferative disease in Chinese: the Queen Mary Hospital experience in Hong Kong
    W Y Au
    The University Department of Medicine, Queen Mary Hospital, University of Hong Kong, Peoples Republic of China
    Leuk Lymphoma 43:1403-7. 2002
    ..The incidence of PTLD is not increased in Chinese patients. However, some patients may be at increased risk, especially mismatched allogeneic BMT, parental OLT (especially involving young infants) and heavy ATG exposure...
  44. ncbi request reprint Disseminated hepatosplenic mycobacterial infection masking myeloproliferative diseases as leukemoid reaction: a diagnostic pitfall
    W Y Au
    Department of Medicine, University Department of Medicine, Queen Mary Hospital, Hong Kong
    Leuk Lymphoma 42:805-8. 2001
    ..Clinicians and hematologist should be aware of such a predisposition and possible dual pathology for proper diagnosis, therapy and monitoring of both the infection and the myeloproliferation...
  45. ncbi request reprint Bcl-3/IgH translocation (14;19)(q32;q13) in non-Hodgkin's lymphomas
    W Y Au
    Department of Pathology and Laboratory Medicine, Vancouver, BC, Canada
    Leuk Lymphoma 43:813-6. 2002
    ..The poor prognosis of t(14;19) disease is associated with the occurrence of recurrent secondary CG changes, commonly found in B cell lymphoproliferative diseases...
  46. ncbi request reprint Risk of haematological malignancies in HLA-B27 carriers
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Br J Haematol 115:320-2. 2001
    ..006). This suggests that HLA-B27 carriers may have an increased risk of acute leukaemia and those with concomitant AS may be predisposed to lymphoid malignancies...
  47. ncbi request reprint Association of the HLA A2-B46-DR9 haplotype with autoimmune thyroid dysfunction after bone marrow transplantation in Chinese patients
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Br J Haematol 115:660-3. 2001
    ..5%, with a relative risk of 7.8 times that of non-carriers (P < 0.001). The risk of AITD should be recognized in recipients with high-risk HLA haplotypes, and regular screening might be warranted...
  48. ncbi request reprint Cytogenetic findings in reactive lymphoid hyperplasia: significance of non-clonal t(3;14) and t(3;22)
    Wing Y Au
    Division of Medical Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    Am J Hematol 70:133-8. 2002
    ..A clonal abnormality is highly predictive of concurrent and/or subsequent lymphoma. A lymphoma-specific but non-clonal abnormality does not necessarily herald the development of subsequent lymphoma...
  49. ncbi request reprint CD30-positive cutaneous T-cell lymphoma with concurrent solid tumour
    W Y Au
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Br J Dermatol 146:1091-5. 2002
    ..In the other patient, lesions regressed spontaneously after bilateral oophorectomy. A possible relationship between the lymphoma and the solid tumours is discussed...
  50. ncbi request reprint Hyposplenism after allogeneic bone marrow transplantation
    Wing Y Au
    Departments of Medicine, Pathology and Nuclear Medicine, Queen Mary Hospital, Hong Kong
    Br J Haematol 117:488. 2002
  51. ncbi request reprint Acute disseminated encephalomyelitis after para-influenza infection post bone marrow transplantation
    Wing Y Au
    University Department of Medicine, Queen Mary Hospital, Hong Kong, People s Republic of China
    Leuk Lymphoma 43:455-7. 2002
    ..There was a rapid and complete response to pulse high-dose corticosteriod and intravenous immunoglobulin. The importance of recognition and early treatment of this rare condition in transplantation practice is emphasized...
  52. ncbi request reprint Intravenous pentamidine induced megaloblastic anaemia
    Wing Y Au
    University Department of Medicine, Professorial Block, Queen Mary Hospital, Pokfulam Road, Hong Kong, ROC
    Haematologica 87:ECR06. 2002
  53. ncbi request reprint Keratoderma blenorrhagica, balanitis and uveitis after HLA-B15 mismatched bone marrow transplantation
    W Y Au
    Department of Dermatology, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Haematologica 87:ECR10. 2002
  54. ncbi request reprint Pentasomy 8q in therapy-related myelodysplastic syndrome due to cyclophosphamide therapy for fibrosing alveolitis
    Wing Y Au
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Cancer Genet Cytogenet 141:79-82. 2003
    ..Increasing copy numbers of chromosome 8/8q may therefore be a marker of advanced leukemic evolution, exposure to toxins, underlying myelodysplasia, and an overall poor prognosis...
  55. ncbi request reprint Clonal marrow abnormalities after azathioprine and sulfasalazine exposure in Crohn's disease: a cautionary tale
    W Y Au
    University Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, People s Republic of China
    Leuk Lymphoma 43:1679-81. 2002
    ..The long-term use of immunodulating agents in patients with CD is not without risks, and early therapy related myelodysplasia might not be easily detected by blood count and morphology assessment alone...
  56. ncbi request reprint Red blood cell alloantibodies and liver transplantation in Chinese patients
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong
    Transplantation 76:324-6. 2003
    ..Red blood cell (RBC) alloantibodies are present in up to 14% of white recipients of liver transplants and can cause severe delayed hemolysis...
  57. ncbi request reprint Primary B-cell lymphoma and lymphoma-like lesions of the uterine cervix
    W Y Au
    Department of Medicine, Obstetrics and Gynecology, Queen Mary Hospital, Hong Kong SAR, China
    Am J Hematol 73:176-9. 2003
    ..With early stage, nonbulky cervical lymphoma in an otherwise healthy patient, a cone biopsy is advised. A number of these lesions may regress even when clonal populations are detected...
  58. ncbi request reprint Tacrolimus (FK 506) induced thrombotic thrombocytopenic purpura after ABO mismatched second liver transplantation: salvage with plasmapheresis and prostacyclin
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong SAR, China
    Haematologica 85:659-62. 2000
    ..Immunosuppression was changed to mycophenolate mofetil. By day 53, the peripheral film and lactate dehydrogenase level had returned to baseline and plasmapheresis was stopped...
  59. ncbi request reprint Peripheral T-cell lymphoma
    Wing Y Au
    University Department of Medicine, Queen Mary Hospital, 4 F Professorial Block, Pokfulam Road, Hong Kong SAR, China
    Curr Oncol Rep 4:434-42. 2002
    ..The role of autologous and allogeneic stem cell transplantation is still poorly defined. Specific antibody-based therapy is also on the horizon...
  60. ncbi request reprint Emergency living related liver transplantation for fulminant reactivation of hepatitis B virus after unrelated marrow transplantation
    W Y Au
    Departments of Medicine, Surgery and Pathology, Queen Mary Hospital, Hong Kong, China
    Clin Transplant 17:121-5. 2003
    ..A choice of marrow and liver donors with innate HBV immunity may be needed to give the additional advantage of long-term HBV clearance...
  61. ncbi request reprint A patient with congenital ichthyosis hystrix (disseminated congenital naevus) and acute lymphoblastic leukaemia
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, 4 F, Professorial Block, Pokfulam Road, Hong Kong, People s Republic of China
    Leuk Lymphoma 44:209-12. 2003
    ..There are four reports of acute leukaemia complicating ichthyosis, all involving paediatric acute lymphoblastic leukaemia. The possible mechanisms involved are discussed...
  62. ncbi request reprint Concurrent mediastinal B cell lymphoma and chronic myeloid leukemia with an unusually favorable response to chemotherapy
    W Y Au
    University Department of Medicine, Professorial Block, Queen Mary Hospital, Pokfulam Road Hong Kong, People s Republic of China
    Leuk Lymphoma 44:535-8. 2003
    ..The relevance of the concomitant occurrence of CML and lymphoma and the unusually favorable response of CML to chemotherapy to the pathogenesis of CML is discussed...
  63. ncbi request reprint Red blood cell alloantibodies and liver transplantation in Chinese patients
    W Y Au
    1 Department of Medicine, Queen Mary Hospital, University of Hong Kong
    Transplantation 75:1904-6. 2003
    ..Delayed hemolysis may jeopardize patient survival as a result of difficult postoperative stabilization, especially in cases requiring massive transfusion...
  64. ncbi request reprint Hairy cell leukemia in Hong Kong Chinese: a 12-year retrospective survey
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Hematol Oncol 18:155-159. 2000
    ..There have been few reports of HCL from oriental countries...
  65. ncbi request reprint A biography of arsenic and medicine in Hong Kong and China
    W Y Au
    University Medicine Unit, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Hong Kong Med J 17:507-13. 2011
    ..The remarkable journey of arsenic in the setting of medical history of China and Hong Kong is reviewed...
  66. ncbi request reprint Bone marrow transplantation for therapy-related acute myeloid leukemia in congenital retinoblastoma associated with 13q deletion syndrome
    C Hon
    Department of Ophthalmology, Queen Mary Hospital, Hong Kong, China
    Ann Hematol 83:481-3. 2004
    ....
  67. ncbi request reprint Long-term results of allogeneic bone marrow transplantation for 108 adult patients with acute lymphoblastic leukemia: favorable outcome with BMT at first remission and HLA-matched unrelated donor
    C S Chim
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, 102 Pokfulam Road, Hong Kong, China
    Bone Marrow Transplant 40:339-47. 2007
    ..In summary, the adverse impact of Ph chromosome, B-cell phenotype and high leukocyte count was overcome by allogeneic BMT. Matched unrelated donor transplantation appears promising...
  68. ncbi request reprint Aggressive hepatocellular carcinoma complicating pregnancy after autologous bone marrow transplantation for non-Hodgkin's lymphoma
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Bone Marrow Transplant 29:177-9. 2002
    ..Biochemical and radiological surveillance for HCC should be strengthened in HBV carriers after BMT, especially in patients with the histology of chronic liver disease, or biochemical/ virological evidence of increased HBV activity...
  69. ncbi request reprint Tyrosine kinase inhibitor STI571 in the treatment of Philadelphia chromosome-positive leukaemia failing myeloablative stem cell transplantation
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Bone Marrow Transplant 30:453-7. 2002
    ..Our results showed that Ph(+) leukaemic relapses after SCT might respond well to STI571 therapy...
  70. ncbi request reprint Treatment of lymphoma relapses after allogeneic hematopoietic stem cell transplantation with intensive chemotherapy followed by infusion of hematopoietic stem cell from the original donor
    W Y Au
    University Department of Medicine, Professorial Block, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Ann Hematol 82:548-51. 2003
    ..Mini-BEAM/HSC is an effective treatment for lymphoma relapses after allogeneic HSCT, but optimal strategies of remission consolidation and prevention of treatment-related complications are needed to improve outcome...
  71. ncbi request reprint Late onset post-transplantation lymphoproliferative disease of recipient origin following cytogenetic relapse and occult autologous haematopoietic regeneration after allogeneic bone marrow transplantation for acute myeloid leukaemia
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Bone Marrow Transplant 28:417-9. 2001
    ..Of further interest is that recipient lymphoid regeneration had accompanied autologous haematopoietic regeneration and become a target for subsequent neoplastic transformation...
  72. ncbi request reprint Trisomy 21 and other chromosomal abnormalities in acute promyelocytic leukemia
    T S K Wan
    Division of Hematology, Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Hong Kong, People s Republic of China
    Cancer Genet Cytogenet 140:170-3. 2003
    ..As APL is now considered a curable disease, any confirmed long-term survival impact of additional cytogenetic changes is expected to have important management implications...
  73. ncbi request reprint Outcome of Chinese patients with chronic myeloid leukaemia (CML) underwent allogeneic bone-marrow transplantation (BMT)
    C K Lee
    Department of Medicine, Queen Mary Hospital, Hong Kong, China
    Am J Hematol 61:85-9. 1999
    ..Therefore, we followed a cohort of 81 Chinese patients who received allogeneic BMT...
  74. ncbi request reprint Liver graft-versus-host disease after donor lymphocyte infusion for relapses of hematologic malignancies post allogeneic hematopoietic stem cell transplantation
    S Y Ma
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Bone Marrow Transplant 34:57-61. 2004
    ..001) and gut (0/11 vs 28/106, P<0.001) involvement. However, liver GVHD post-DLI and post-HSCT had comparable patient characteristics, underlying diseases, clinical subtypes (classical and hepatitic) and response to treatment...
  75. ncbi request reprint Arsenic trioxide- and idarubicin-induced remissions in relapsed acute promyelocytic leukaemia: clinicopathological and molecular features of a pilot study
    Y L Kwong
    University Department of Medicine, Queen Mary Hospital, Hong Kong
    Am J Hematol 66:274-9. 2001
    ..This regimen avoids the possible long-term toxicities of As2O3 and mutagenicity of combination chemotherapy, a strategy that might be suitable for this potentially curable leukaemia...
  76. ncbi request reprint Philadelphia (Ph) chromosome-positive chronic myeloid leukaemia relapsing as Ph-negative leukaemia after allogeneic bone marrow transplantation
    W Y Au
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Br J Haematol 114:365-8. 2001
    ....
  77. ncbi request reprint Respiratory ciliary function in bone marrow recipients
    W Y Au
    University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
    Bone Marrow Transplant 27:1147-51. 2001
    ..Further studies are indicated to evaluate this important phenomenon, which could be an important cause of the susceptibility for BMT recipients to respiratory infections...
  78. ncbi request reprint Haematopoietic stem cell transplantation in Hong Kong
    Albert K W Lie
    University Department of Medicine, Queen Mary Hospital, University of Hong Kong, Pokfulam Road, Hong Kong
    Hong Kong Med J 15:17-21. 2009
    ..Transplant outcomes are reported to the Center for International Blood and Marrow Transplant Research and long-term survivals are in general comparable to international standard...
  79. ncbi request reprint Derivative (1;18)(q10;q10): a recurrent and novel unbalanced translocation involving 1q in myeloid disorders
    T S Wan
    Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, People's Republic of China
    Cancer Genet Cytogenet 128:35-8. 2001
    ..Finally, chromosomes with large constitutive heterochromatin bands such as chromosome 1 may be at risk of centromeric instability and be predisposed to centromeric fusion with other chromosomes...
  80. ncbi request reprint Leukaemic relapse of donor origin after allogeneic bone marrow transplantation from a donor who later developed bronchogenic carcinoma
    W Y Au
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Br J Haematol 119:777-80. 2002
    ..Sequencing of p53 ruled out Li-Fraumeni syndrome. Predisposition to malignancy might be an underlying mechanism of donor-cell leukaemia...
  81. ncbi request reprint Use of famciclovir to prevent HBV reactivation in HBsAg-positive recipients after allogeneic bone marrow transplantation
    G K Lau
    Department of Medicine, Queen Mary Hospital, Hong Kong
    J Hepatol 28:359-68. 1998
    ..We have studied the effect of famciclovir on the incidence of hepatitis B virus reactivation and hepatitis after allogeneic bone marrow transplantation...
  82. ncbi request reprint Non-myeloablative allogeneic peripheral stem cell transplantation for multiple myeloma
    S Y Ma
    Division of Haematology and Oncology, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Hong Kong Med J 10:77-83. 2004
    ..To present an institution's 2-year experience of non-myeloablative allogeneic stem cell transplantation among Chinese patients...
  83. ncbi request reprint Aberrant p15 gene promoter methylation in therapy-related myelodysplastic syndrome and acute myeloid leukaemia: clinicopathological and karyotypic associations
    W Y Au
    University Department of Medicine, Queen Mary Hospital, Hong Kong
    Br J Haematol 120:1062-5. 2003
    ..Bone marrow transplantation led to the disappearance of p15 methylation in one patient. These results showed that p15 methylation was an early event in the evolution of some t-MDS/AML patients...
  84. ncbi request reprint Combined arsenic trioxide and all-trans retinoic acid treatment for acute promyelocytic leukaemia recurring from previous relapses successfully treated using arsenic trioxide
    W Y Au
    University Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Br J Haematol 117:130-2. 2002
    ..Our results suggest a synergistic therapeutic effect between As2O3 and ATRA in APL in advanced relapse...
  85. pmc Primitive small round cell tumour of the adrenal gland presenting with fever of unknown origin and t(12;22)(q13;q12) cytogenetic finding
    K Y Lam
    Department of Pathology, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, China
    J Clin Pathol 54:966-9. 2001
    ..This is the first example of such a tumour being reported in the adrenal gland. The adrenal tumour was also the cause of the fever, which subsided after the removal of the tumour...
  86. ncbi request reprint Growth of giant hepatic hemangioma after triplet pregnancy
    Wing Yan Au
    Department of Surgery, Queen Mary Hospital, University of Hong Kong, Hong Kong
    J Hepatol 42:781. 2005
  87. ncbi request reprint Reduced incidence of acute graft versus host disease (GVHD) of the gut in Chinese carriers of Helicobacter pylori during allogeneic bone marrow transplantation
    W Y Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Pokfulam Road, Hong Kong, China
    Ann Hematol 83:34-7. 2004
    ..04) but not overall GVHD. The reduced risk of immune-mediated gut inflammation in H. Pylori carriers after SCT may be related to the known reduced incidence of inflammatory bowel disease in chronic H. Pylori carriers...
  88. ncbi request reprint Quantification of circulating Epstein-Barr virus (EBV) DNA in the diagnosis and monitoring of natural killer cell and EBV-positive lymphomas in immunocompetent patients
    Wing Yan Au
    Department of Medicine, Queen Mary Hospital, University of Hong Kong
    Blood 104:243-9. 2004
    ..During treatment, patients with EBV DNA that showed further increases or failed to become undetectable had significantly inferior OS. In EBV-positive lymphomas, plasma EBV DNA is valuable as a tumor biomarker and for prognostication...
  89. ncbi request reprint Transferrin receptor-2 polymorphisms and iron overload in transfusion independent b-thalassemia intermedia
    Edmond S K Ma
    Haematologica 88:345-6. 2003
  90. ncbi request reprint Role of liver biopsy in the management of liver dysfunction after hematopoietic stem-cell transplantation in a hepatitis B virus-prevalent patient population
    Shing Yan Ma
    University Department of Medicine, Queen Mary Hospital, Hong Kong
    Transplantation 76:169-76. 2003
    ..The role of liver biopsy in such cases has not been defined in hepatitis B virus (HBV)-prevalent patients. The impact of liver biopsy in the management of LFT derangement after HSCT in an HBV-prevalent population was examined...
  91. ncbi request reprint Primary nasal natural killer cell lymphoma: long-term treatment outcome and relationship with the International Prognostic Index
    Chor Sang Chim
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Blood 103:216-21. 2004
    ..4% versus 27.6%, P = 0.012), as well as for patients treated with chemotherapy/radiotherapy (IPI <or= 1 superior to IPI >or= 2 for CR: 76.7% versus 35.7%, P =.017; and 10-year OS: 63.8% versus 26.8%, P =.003)...
  92. ncbi request reprint Myelodysplastic syndrome and acute myeloid leukemia after treatment with fludarabine, mitoxantrone, and dexamethasone
    Wing Yan Au
    Am J Hematol 81:471-3. 2006
  93. ncbi request reprint Alemtuzumab induced complete remission of therapy-resistant pure red cell aplasia
    Wing Yan Au
    University Department of Medicine, Professorial Block, Queen Mary Hospital, Pokfulam Road, Hong Kong, China
    Leuk Res 29:1213-5. 2005
    ..There were no significant side effects, and normalization of erythropoiesis was durable. Alemtuzumab is active in PRCA that is idiopathic or secondary to T-cell lymphoproliferative diseases...
  94. ncbi request reprint Epstein-barr virus-related gastric adenocarcinoma: an early secondary cancer post hemopoietic stem cell transplantation
    Wing Yan Au
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Gastroenterology 129:2058-63. 2005
    ..Epstein-Barr virus (EBV) infection has been associated with some cases of gastric cancer...
  95. ncbi request reprint Concomitant post-transplantation lymphoproliferative disease and therapy-related myelodysplastic syndrome after lung transplantation
    Wing Yan Au
    J Heart Lung Transplant 25:259-60. 2006
  96. ncbi request reprint Cough mixture abuse as a novel cause of folate deficiency: a prospective, community-based, controlled study
    Wing Yan Au
    Haematologica 92:562-3. 2007
    ..A total of 57 cough mixture abusers and 47 other substance abusers (controls) were studied. When compared with controls, cough mixture abusers had a high incidence of low folate levels that could only be detected by screening...
  97. ncbi request reprint Oral arsenic trioxide therapy for acute promyelocytic leukemia before and after liver transplantation for hepatitis B virus-related liver failure
    Wing Yan Au
    Ann Hematol 86:771-2. 2007