Fu Hua Wang

Summary

Affiliation: AstraZeneca R and D

Publications

  1. doi request reprint Decreased axonal transport rates in the Tg2576 APP transgenic mouse: improvement with the gamma-secretase inhibitor MRK-560 as detected by manganese-enhanced MRI
    Fu Hua Wang
    AstraZeneca Research and Development, Innovative Medicines, SE 15185 Sodertalje, Sweden
    Eur J Neurosci 36:3165-72. 2012
  2. pmc Kv1.1 null mice have enlarged hippocampus and ventral cortex
    Ann Sophie Persson
    Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    BMC Neurosci 8:10. 2007

Collaborators

  • Ann Sophie Persson
  • Firoj Hossain Khan
  • Christian Spenger
  • Eric Westman
  • Catharina Lavebratt

Detail Information

Publications2

  1. doi request reprint Decreased axonal transport rates in the Tg2576 APP transgenic mouse: improvement with the gamma-secretase inhibitor MRK-560 as detected by manganese-enhanced MRI
    Fu Hua Wang
    AstraZeneca Research and Development, Innovative Medicines, SE 15185 Sodertalje, Sweden
    Eur J Neurosci 36:3165-72. 2012
    ..Chronic treatment in vivo with a gamma-secretase inhibitor, MRK-560, significantly reduces soluble and insoluble forms of Aβ, and fully reverses the axonal transport dysfunction...
  2. pmc Kv1.1 null mice have enlarged hippocampus and ventral cortex
    Ann Sophie Persson
    Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    BMC Neurosci 8:10. 2007
    ..1 are known to cause episodic ataxia type 1 and temporal lobe epilepsy. Mice that express a malfunctional, truncated Kv1.1 (BALB/cByJ-Kv1.1mceph/mceph) show a markedly enlarged hippocampus and ventral cortex in adulthood...