S G Simonson

Summary

Affiliation: AstraZeneca R and D

Publications

  1. ncbi request reprint Comparative effects of rosuvastatin and atorvastatin across their dose ranges in patients with hypercholesterolemia and without active arterial disease
    Dennis W Schneck
    AstraZeneca LP, Wilmington, Delaware 19850 5437, USA
    Am J Cardiol 91:33-41. 2003
  2. ncbi request reprint Pharmacokinetics and pharmacodynamics of rosuvastatin in subjects with hepatic impairment
    S G Simonson
    AstraZeneca, R and D Lund, Experimental Medicine, SE 221 87 Lund, Sweden
    Eur J Clin Pharmacol 58:669-75. 2003
  3. pmc The effect of rosuvastatin on oestrogen & progestin pharmacokinetics in healthy women taking an oral contraceptive
    Steven G Simonson
    AstraZeneca, Lund, Sweden
    Br J Clin Pharmacol 57:279-86. 2004
  4. ncbi request reprint Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine
    Steven G Simonson
    AstraZeneca, Wilmington, Del, USA
    Clin Pharmacol Ther 76:167-77. 2004
  5. ncbi request reprint Rosuvastatin improves the atherogenic and atheroprotective lipid profiles in patients with hypertriglyceridemia
    Donald B Hunninghake
    Heart Disease Prevention Clinic, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Coron Artery Dis 15:115-23. 2004
  6. ncbi request reprint Effect of rosuvastatin on warfarin pharmacodynamics and pharmacokinetics
    Steven G Simonson
    AstraZeneca, 1800 Concord Pike, PO Box 15437, Wilmington, DE 19850 5437, USA
    J Clin Pharmacol 45:927-34. 2005
  7. ncbi request reprint Evaluation of efficacy and safety of budesonide delivered via two dry powder inhalers
    Edward M Kerwin
    Clinical Research Institute of Southern Oregon, Medford, OR 97504, USA
    Curr Med Res Opin 24:1497-510. 2008
  8. ncbi request reprint Zafirlukast treatment for acute asthma: evaluation in a randomized, double-blind, multicenter trial
    Robert A Silverman
    Long Island Jewish Medical Center, 270 05 76th Ave, New Hyde Park, NY 11042, USA
    Chest 126:1480-9. 2004

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Comparative effects of rosuvastatin and atorvastatin across their dose ranges in patients with hypercholesterolemia and without active arterial disease
    Dennis W Schneck
    AstraZeneca LP, Wilmington, Delaware 19850 5437, USA
    Am J Cardiol 91:33-41. 2003
    ..Significantly greater triglyceride decreases were seen at 80 mg with atorvastatin over rosuvastatin. Both rosuvastatin and atorvastatin were well tolerated over 6 weeks...
  2. ncbi request reprint Pharmacokinetics and pharmacodynamics of rosuvastatin in subjects with hepatic impairment
    S G Simonson
    AstraZeneca, R and D Lund, Experimental Medicine, SE 221 87 Lund, Sweden
    Eur J Clin Pharmacol 58:669-75. 2003
    ..To assess the effect of chronic hepatic impairment on rosuvastatin disposition, pharmacodynamic activity and tolerability...
  3. pmc The effect of rosuvastatin on oestrogen & progestin pharmacokinetics in healthy women taking an oral contraceptive
    Steven G Simonson
    AstraZeneca, Lund, Sweden
    Br J Clin Pharmacol 57:279-86. 2004
    ..To assess the effect of rosuvastatin on oestrogen and progestin pharmacokinetics in women taking a commonly prescribed combination oral contraceptive steroid (OCS); the effect on endogenous hormones and the lipid profile was also assessed...
  4. ncbi request reprint Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine
    Steven G Simonson
    AstraZeneca, Wilmington, Del, USA
    Clin Pharmacol Ther 76:167-77. 2004
    ..Inhibition of this transporter could increase plasma concentrations of rosuvastatin. Therefore the effect of cyclosporine on rosuvastatin uptake by cells expressing OATP-C was also examined...
  5. ncbi request reprint Rosuvastatin improves the atherogenic and atheroprotective lipid profiles in patients with hypertriglyceridemia
    Donald B Hunninghake
    Heart Disease Prevention Clinic, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Coron Artery Dis 15:115-23. 2004
    ..We examined the effects of rosuvastatin treatment on triglyceride levels and lipid measures in a parallel-group multicenter trial (4522IL/0035) in patients with hypertriglyceridemia (Fredrickson Type IIb or IV)...
  6. ncbi request reprint Effect of rosuvastatin on warfarin pharmacodynamics and pharmacokinetics
    Steven G Simonson
    AstraZeneca, 1800 Concord Pike, PO Box 15437, Wilmington, DE 19850 5437, USA
    J Clin Pharmacol 45:927-34. 2005
    ..Appropriate monitoring of the international normalized ratio is indicated when this drug combination is coadministered...
  7. ncbi request reprint Evaluation of efficacy and safety of budesonide delivered via two dry powder inhalers
    Edward M Kerwin
    Clinical Research Institute of Southern Oregon, Medford, OR 97504, USA
    Curr Med Res Opin 24:1497-510. 2008
    ..The dry powder inhaler (DPI) device for budesonide inhalation powder 200 microg (DPI-A) was redesigned to improve dosing consistency and provide new features (budesonide inhalation powder 90 microg and 180 microg; DPI-B)...
  8. ncbi request reprint Zafirlukast treatment for acute asthma: evaluation in a randomized, double-blind, multicenter trial
    Robert A Silverman
    Long Island Jewish Medical Center, 270 05 76th Ave, New Hyde Park, NY 11042, USA
    Chest 126:1480-9. 2004
    ..Acute asthma causes nearly 2 million hospital emergency department (ED) visits in the United States annually, and hospitalization after an ED visit and relapse after ED discharge are common...