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Affiliation: AstraZeneca R and D
Little R, Barjat H, Hare J, Jenner M, Watson Y, Cheung S, et al. Evaluation of dynamic contrast-enhanced MRI biomarkers for stratified cancer medicine: How do permeability and perfusion vary between human tumours?. Magn Reson Imaging. 2018;46:98-105 pubmed publisher
..Instead, Ktrans is an idiopathic parameter, and, where permeability is important, Ktrans should be measured in each tumour to personalise that treatment. ..