Affiliation: AstraZeneca R and D
- Few alterations in clinical pathology and histopathology observed in a CYP2C18&19 humanized mice modelSusanne Löfgren
Safety Assessment Sweden, AstraZeneca R and D Sodertalje, S 151 85 Södertälje, Sweden
Acta Vet Scand 50:47. 2008..This study was performed to characterize a gene-addition transgenic mouse containing a BAC (bacterial artificial chromosome) clone spanning the human CYP2C18&19 genes (tg-CYP2C18&19)...
- Regulation of human CYP2C18 and CYP2C19 in transgenic mice: influence of castration, testosterone, and growth hormoneSusanne Löfgren
Safety Assessment Sweden, AstraZeneca R and D, Department of Pathology, B681 2, 15185 Södertälje, Sweden
Drug Metab Dispos 37:1505-12. 2009....