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Emre M Isin
Affiliation: AstraZeneca R and D
Iegre J, Hayes M, Thompson R, Weidolf L, Isin E. Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data. Drug Metab Dispos. 2016;44:732-40 pubmed publisher
..This retrospective analysis assesses the predictive value of Met-ID experiments and improves our ability to discriminate between metabolites expected to circulate in humans and irrelevant metabolites seen in preclinical studies. ..