Research Topics
| Steven J EdwardsSummaryAffiliation: AstraZeneca R and D Publications
| Collaborators |
Detail Information
Publications
Systematic review of proton pump inhibitors for the acute treatment of reflux oesophagitisS J Edwards
Outcomes Research, AstraZeneca, Kings Langley, UK
Aliment Pharmacol Ther 15:1729-36. 2001..Esomeprazole is a new proton pump inhibitor, which has been compared to omeprazole for the treatment of reflux oesophagitis in clinical trials...
Tolerability of atypical antipsychotics in the treatment of adults with schizophrenia or bipolar disorder: a mixed treatment comparison of randomized controlled trialsSteven J Edwards
AstraZeneca UK Ltd, Luton, United Kingdom
Clin Ther 31:1345-59. 2009..This article reviews and compares the tolerability profiles of atypical antipsychotics in adults with schizophrenia or bipolar disorder in randomized controlled trials (RCTs)...
Systematic review and meta-analysis of budesonide/formoterol in a single inhalerSteven J Edwards
Outcomes Research, AstraZeneca UK Ltd, Luton, Bedfordshire, UK
Curr Med Res Opin 23:1809-20. 2007..To compare the effectiveness of budesonide/formoterol using fixed dosing (BUD/FORM) with inhaled corticosteroid (ICS) alone or alternative ICS and long-acting beta(2)-agonist (LABA) regimens for adults with moderate/severe asthma...
Budesonide/formoterol for maintenance and reliever therapy of asthma: a meta analysis of randomised controlled trialsS J Edwards
Outcomes Research, AstraZeneca UK Ltd, Luton, UK
Int J Clin Pract 64:619-27. 2010....
Systematic review: proton pump inhibitors (PPIs) for the healing of reflux oesophagitis - a comparison of esomeprazole with other PPIsS J Edwards
Outcomes Research, AstraZeneca UK Ltd, Luton, Bedfordshire, UK
Aliment Pharmacol Ther 24:743-50. 2006..No randomized controlled trial has compared all the licensed standard dose proton pump inhibitors in the healing of reflux oesophagitis...
Cost-utility analysis comparing meropenem with imipenem plus cilastatin in the treatment of severe infections in intensive careSteven J Edwards
AstraZeneca UK Ltd, Luton, UK
Eur J Health Econ 7:72-8. 2006..62) and more effective (0.084, 95% CI 0.023 to 0.144). Meropenem thus appears significantly more effective and less expensive than imipenem plus cilastatin and should therefore be considered the dominant treatment strategy...
Systematic review comparing meropenem with imipenem plus cilastatin in the treatment of severe infectionsSteven J Edwards
Outcomes Research Department, AstraZeneca UK Ltd, Luton, Bedfordshire, UK
Curr Med Res Opin 21:785-94. 2005..To compare the effectiveness of meropenem with imipenem plus cilastatin in the treatment of severe infections...
A review of the clinical and economic impact of using esomeprazole or lansoprazole for the treatment of erosive esophagitisAnan S Raghunath
St. Andrews Group Practice, Hull, Luton, United Kingdom
Clin Ther 25:2088-101. 2003..CONCLUSION: The currently available comparative data for esomeprazole and lansoprazole indicate clinical and cost-effectiveness advantages for esomeprazole in the healing and maintenance of erosive esophagitis compared with lansoprazole...
Comparison of sequential rosuvastatin doses in hypercholesterolaemia: a meta-analysis of randomised controlled trialsJoe Gray
AstraZeneca UK Ltd, Luton, UK
Curr Med Res Opin 26:537-47. 2010..However, the incremental benefit and risk of increasing through the licensed dose range have not been comprehensively assessed across all available clinical trials...
Systematic review: standard- and double-dose proton pump inhibitors for the healing of severe erosive oesophagitis -- a mixed treatment comparison of randomized controlled trialsS J Edwards
Outcomes Research, AstraZeneca UK Ltd, Luton, UK
Aliment Pharmacol Ther 30:547-56. 2009..No randomized controlled trial (RCT) has compared all European-licensed standard- and double-dose PPIs for the healing of severe erosive oesophagitis...
Stroke prevention with aspirin, warfarin and ximelagatran in patients with non-valvular atrial fibrillation: a systematic review and meta-analysisGregory Y H Lip
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
Thromb Res 118:321-33. 2006..To compare the effectiveness of aspirin, warfarin, and ximelagatran as thromboprophylaxis in patients with non-valvular atrial fibrillation (NVAF)...
Systematic review of early vs deferred hormonal treatment of locally advanced prostate cancer: a meta-analysis of randomized controlled trialsGregory Boustead
Department of Urology, Lister Hospital, Stevenage, UK
BJU Int 99:1383-9. 2007....
