Ian A Cotgreave

Summary

Affiliation: AstraZeneca R and D

Publications

  1. ncbi request reprint Analytical developments in the assay of intra- and extracellular GSH homeostasis: specific protein S-glutathionylation, cellular GSH and mixed disulphide compartmentalisation and interstitial GSH redox balance
    Ian A Cotgreave
    Division of Biochemical Toxicology, Institute of Environmental Medicine, Karolinska Institute, Box 210, S 17177 Stockholm, Sweden
    Biofactors 17:269-77. 2003
  2. ncbi request reprint Biological stress responses to radio frequency electromagnetic radiation: are mobile phones really so (heat) shocking?
    Ian A Cotgreave
    Division of Biochemical Toxicology, Institute of Environmental Medicine, Karolinska Institute, Box 210, S 17177 Stockholm, Sweden
    Arch Biochem Biophys 435:227-40. 2005
  3. doi request reprint H2AX phosphorylation in A549 cells induced by the bulky and stable DNA adducts of benzo[a]pyrene and dibenzo[a,l]pyrene diol epoxides
    Ase Mattsson
    Institute of Environmental Medicine, Division of Biochemical Toxicology, Karolinska Institutet, Box 210, S 171 77 Stockholm, Sweden
    Chem Biol Interact 177:40-7. 2009
  4. ncbi request reprint Hydrogen peroxide causes greater oxidation in cellular RNA than in DNA
    Tim Hofer
    Institute of Environmental Medicine, Karolinska Institute, Box 210, S 171 77 Stockholm, Sweden
    Biol Chem 386:333-7. 2005
  5. ncbi request reprint Determination of site-specificity of S-glutathionylated cellular proteins
    Ylva Hamnell-Pamment
    Division of Biochemical Toxicology, Institute of Environmental Medicine, Karolinska Institute, Stockholm SE 17177, Sweden
    Biochem Biophys Res Commun 332:362-9. 2005
  6. ncbi request reprint Identification of S-glutathionylated cellular proteins during oxidative stress and constitutive metabolism by affinity purification and proteomic analysis
    Christina Lind
    Division of Biochemical Toxicology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    Arch Biochem Biophys 406:229-40. 2002
  7. ncbi request reprint Protein S-glutathionylation correlates to selective stress gene expression and cytoprotection
    Tiziana Dandrea
    Division of Biochemical Toxicology, National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Arch Biochem Biophys 406:241-52. 2002
  8. ncbi request reprint Visualization of the compartmentalization of glutathione and protein-glutathione mixed disulfides in cultured cells
    Therese Söderdahl
    Division of Biochemical Toxicology, Karolinska Institutet, Stockholm Sweden
    FASEB J 17:124-6. 2003

Collaborators

  • Tim Hofer
  • Sten Orrenius
  • Christina Lind
  • Ase Mattsson
  • Edyta Bajak
  • Ylva Hamnell-Pamment
  • Therese Söderdahl
  • Arne Holmgren
  • Tiziana Dandrea
  • Bengt Jernström
  • Tomas Bergman
  • Carina Palmberg
  • Ole P Ottersen
  • Mari Enoksson
  • George Bolcsfoldi
  • Mathias Lundberg
  • Ina Schuppe-Koistinen
  • Lars Wärngård
  • Helena Brockenhuus von Löwenhielm
  • Robert Gerdes
  • Ylva Hamnell

Detail Information

Publications8

  1. ncbi request reprint Analytical developments in the assay of intra- and extracellular GSH homeostasis: specific protein S-glutathionylation, cellular GSH and mixed disulphide compartmentalisation and interstitial GSH redox balance
    Ian A Cotgreave
    Division of Biochemical Toxicology, Institute of Environmental Medicine, Karolinska Institute, Box 210, S 17177 Stockholm, Sweden
    Biofactors 17:269-77. 2003
  2. ncbi request reprint Biological stress responses to radio frequency electromagnetic radiation: are mobile phones really so (heat) shocking?
    Ian A Cotgreave
    Division of Biochemical Toxicology, Institute of Environmental Medicine, Karolinska Institute, Box 210, S 17177 Stockholm, Sweden
    Arch Biochem Biophys 435:227-40. 2005
    ..Therefore, the validity of these effects in human health risk assessment remain unsubstantiated. Where possible, suggestions for further experimental clarification have been provided...
  3. doi request reprint H2AX phosphorylation in A549 cells induced by the bulky and stable DNA adducts of benzo[a]pyrene and dibenzo[a,l]pyrene diol epoxides
    Ase Mattsson
    Institute of Environmental Medicine, Division of Biochemical Toxicology, Karolinska Institutet, Box 210, S 171 77 Stockholm, Sweden
    Chem Biol Interact 177:40-7. 2009
    ..Thus, the extent of H2AXgamma formation and persistence was related to both the number of adducts and their structural features...
  4. ncbi request reprint Hydrogen peroxide causes greater oxidation in cellular RNA than in DNA
    Tim Hofer
    Institute of Environmental Medicine, Karolinska Institute, Box 210, S 171 77 Stockholm, Sweden
    Biol Chem 386:333-7. 2005
    ..The A549 showed slow turnover rates of adducts in RNA and DNA giving half-lives of approximately 12.5 h for [18O]-8-oxoGuo in RNA and 20.7 h for [18O]-8-oxodGuo in DNA, respectively...
  5. ncbi request reprint Determination of site-specificity of S-glutathionylated cellular proteins
    Ylva Hamnell-Pamment
    Division of Biochemical Toxicology, Institute of Environmental Medicine, Karolinska Institute, Stockholm SE 17177, Sweden
    Biochem Biophys Res Commun 332:362-9. 2005
    ..Further developments of accuracy within the field of peptide-affinity capture and mass spectrometry are discussed...
  6. ncbi request reprint Identification of S-glutathionylated cellular proteins during oxidative stress and constitutive metabolism by affinity purification and proteomic analysis
    Christina Lind
    Division of Biochemical Toxicology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    Arch Biochem Biophys 406:229-40. 2002
    ....
  7. ncbi request reprint Protein S-glutathionylation correlates to selective stress gene expression and cytoprotection
    Tiziana Dandrea
    Division of Biochemical Toxicology, National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Arch Biochem Biophys 406:241-52. 2002
    ....
  8. ncbi request reprint Visualization of the compartmentalization of glutathione and protein-glutathione mixed disulfides in cultured cells
    Therese Söderdahl
    Division of Biochemical Toxicology, Karolinska Institutet, Stockholm Sweden
    FASEB J 17:124-6. 2003
    ..Similar FACS analyses performed in isolated mitochondria presented a considerable variation in GSH content within mitochondria of uniform granularity from the same preparation...