Michael Arthur

Summary

Publications

  1. ncbi Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis
    Frank R Murphy
    Liver Group, Division of Infection, Inflammation and Repair, University of Southampton, Hampshire SO16 6YD, United Kingdom
    J Biol Chem 277:11069-76. 2002
  2. ncbi Developing strategies for liver fibrosis treatment
    Frank Murphy
    Liver Research Group, Division of Infection, Inflammation and Repair, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD, UK
    Expert Opin Investig Drugs 11:1575-85. 2002
  3. ncbi Engagement of alphavbeta3 integrin regulates proliferation and apoptosis of hepatic stellate cells
    Xiaoying Zhou
    Liver Research Group, University Division of Infection, Inflammation and Repair, Southampton General Hospital, United Kingdom
    J Biol Chem 279:23996-4006. 2004
  4. ncbi High efficiency gene transfer into cultured primary rat and human hepatic stellate cells using baculovirus vectors
    Runping Gao
    Liver Group, Division of Infection, Inflammation and Repair, University of Southampton, Level D, South Academic Block, Southampton General Hospital, Tremona Road, Southampton, UK
    Liver 22:15-22. 2002

Collaborators

  • Hideaki Nagase
  • John Iredale
  • Junlong Zhang
  • Frank R Murphy
  • Xiaoying Zhou
  • Runping Gao
  • Frank Murphy
  • Nitu Gehdu
  • R Christopher Benyon
  • David E Smart
  • Christopher Benyon
  • Shabna Ratnarajah
  • Fiona Oakley
  • Richard Ruddell
  • Derek A Mann
  • Mark P G Harris
  • Razao Issa
  • Christopher J McCormick

Detail Information

Publications4

  1. ncbi Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis
    Frank R Murphy
    Liver Group, Division of Infection, Inflammation and Repair, University of Southampton, Hampshire SO16 6YD, United Kingdom
    J Biol Chem 277:11069-76. 2002
    ..We conclude that TIMP-1 inhibits apoptosis of activated HSC via MMP inhibition...
  2. ncbi Developing strategies for liver fibrosis treatment
    Frank Murphy
    Liver Research Group, Division of Infection, Inflammation and Repair, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD, UK
    Expert Opin Investig Drugs 11:1575-85. 2002
    ..The detailed understanding of hepatic stellate cell biology has allowed the rational design of novel antifibrotic therapies. This review describes for the general reader the novel emerging therapies for liver fibrosis...
  3. ncbi Engagement of alphavbeta3 integrin regulates proliferation and apoptosis of hepatic stellate cells
    Xiaoying Zhou
    Liver Research Group, University Division of Infection, Inflammation and Repair, Southampton General Hospital, United Kingdom
    J Biol Chem 279:23996-4006. 2004
    ....
  4. ncbi High efficiency gene transfer into cultured primary rat and human hepatic stellate cells using baculovirus vectors
    Runping Gao
    Liver Group, Division of Infection, Inflammation and Repair, University of Southampton, Level D, South Academic Block, Southampton General Hospital, Tremona Road, Southampton, UK
    Liver 22:15-22. 2002
    ..CONCLUSIONS: Baculovirus vectors can therefore be used to deliver target genes to cultured rat and human HSC with high efficiency and longevity in the absence of detrimental effects on cell function...