Laura N Arneson

Summary

Publications

  1. ncbi request reprint Cutting edge: syntaxin 11 regulates lymphocyte-mediated secretion and cytotoxicity
    Laura N Arneson
    Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Immunol 179:3397-401. 2007
  2. pmc Dynamin 2 regulates granule exocytosis during NK cell-mediated cytotoxicity
    Laura N Arneson
    Department of Immunology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Immunol 181:6995-7001. 2008
  3. ncbi request reprint Differential regulation of human NK cell-mediated cytotoxicity by the tyrosine kinase Itk
    Dianne Khurana
    Department of Immunology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    J Immunol 178:3575-82. 2007
  4. pmc TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells
    Suresh Radhakrishnan
    Department of Immunology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Immunol 181:7863-72. 2008
  5. ncbi request reprint NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells
    Jadee L Upshaw
    Department of Immunology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Nat Immunol 7:524-32. 2006

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Cutting edge: syntaxin 11 regulates lymphocyte-mediated secretion and cytotoxicity
    Laura N Arneson
    Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Immunol 179:3397-401. 2007
    ..Our data identify and characterize a role for syntaxin 11 in granule exocytosis and in the generation of cell-mediated killing. These results also provide new insights on the mechanisms of hemopoietic dysregulation in FHL...
  2. pmc Dynamin 2 regulates granule exocytosis during NK cell-mediated cytotoxicity
    Laura N Arneson
    Department of Immunology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Immunol 181:6995-7001. 2008
    ..These findings identify a novel role for Dyn2 in the exocytic events required for effective NK cell-mediated cytotoxicity...
  3. ncbi request reprint Differential regulation of human NK cell-mediated cytotoxicity by the tyrosine kinase Itk
    Dianne Khurana
    Department of Immunology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    J Immunol 178:3575-82. 2007
    ..Moreover, understanding how these pathways may be differentially regulated has relevance in the setting of autoimmune diseases and antitumor immune responses where NK cells play key regulatory roles...
  4. pmc TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells
    Suresh Radhakrishnan
    Department of Immunology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Immunol 181:7863-72. 2008
    ..The parallel signaling events observed in both human and mouse mDC support the hypothesis that B7-DC cross-linking may be useful as a therapeutic immune modulator in human patients...
  5. ncbi request reprint NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells
    Jadee L Upshaw
    Department of Immunology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Nat Immunol 7:524-32. 2006
    ..These findings identify a previously unknown mechanism by which NKG2D-DAP10 mediates cytotoxicity and provides a framework for evaluating activation by other receptor complexes that lack immunoreceptor tyrosine-based activation motifs...