Gary A B Armstrong

Summary

Publications

  1. doi Calcium channel agonists protect against neuromuscular dysfunction in a genetic model of TDP-43 mutation in ALS
    Gary A B Armstrong
    Department of Pathology and Cell Biology and Groupe de Recherche sur le Système Nerveux Central, Universite de Montreal, Montreal, QC, H3C 3J7, Canada
    J Neurosci 33:1741-52. 2013
  2. doi Cold hardening modulates K+ homeostasis in the brain of Drosophila melanogaster during chill coma
    Gary A B Armstrong
    Department of Biology, Queen s University, Kingston, ON, Canada K7L 3N6
    J Insect Physiol 58:1511-6. 2012
  3. pmc Glial Hsp70 protects K+ homeostasis in the Drosophila brain during repetitive anoxic depolarization
    Gary A B Armstrong
    Department of Biology, Queen s University, Kingston, Ontario, Canada
    PLoS ONE 6:e28994. 2011
  4. doi Inhibition of protein kinase G activity protects neonatal mouse respiratory network from hyperthermic and hypoxic stress
    Gary A B Armstrong
    Department of Biology, Queen s University, Biosciences Complex, Kingston ON, Canada
    Brain Res 1311:64-72. 2010
  5. pmc Natural variation in the thermotolerance of neural function and behavior due to a cGMP-dependent protein kinase
    Ken Dawson-Scully
    University of Toronto, Department of Biology, Mississauga, Ontario, Canada
    PLoS ONE 2:e773. 2007
  6. ncbi Suppression of spreading depression-like events in locusts by inhibition of the NO/cGMP/PKG pathway
    Gary A B Armstrong
    Department of Biology, Queen s University, Kingston, Ontario K7L 3N6, Canada
    J Neurosci 29:8225-35. 2009
  7. doi Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS
    Gary A B Armstrong
    Department of Pathology and Cell Biology and Groupe de Recherche sur le Système Nerveux Central, Universite de Montreal, Montreal, QC, Canada H3C 3J7
    Hum Mol Genet 22:4282-92. 2013
  8. doi Coma in response to environmental stress in the locust: a model for cortical spreading depression
    Corinne I Rodgers
    Department of Biology, Queen s University, Biosciences Complex, Kingston, Ontario, Canada
    J Insect Physiol 56:980-90. 2010
  9. pmc Stress preconditioning of spreading depression in the locust CNS
    Corinne I Rodgers
    Department of Biology, Queen s University, Biosciences Complex, Kingston, Ontario, Canada
    PLoS ONE 2:e1366. 2007
  10. doi Metabolic stress modulates motor patterning via AMP-activated protein kinase
    Corinne I Rodgers-Garlick
    Department of Biology, Queen s University, Kingston, Ontario K7L 3N6, Canada
    J Neurosci 31:3207-16. 2011

Detail Information

Publications11

  1. doi Calcium channel agonists protect against neuromuscular dysfunction in a genetic model of TDP-43 mutation in ALS
    Gary A B Armstrong
    Department of Pathology and Cell Biology and Groupe de Recherche sur le Système Nerveux Central, Universite de Montreal, Montreal, QC, H3C 3J7, Canada
    J Neurosci 33:1741-52. 2013
    ..These results indicate that expression of mutTARDBP results in defective NMJs and that calcium channel agonists could be novel therapeutics for ALS...
  2. doi Cold hardening modulates K+ homeostasis in the brain of Drosophila melanogaster during chill coma
    Gary A B Armstrong
    Department of Biology, Queen s University, Kingston, ON, Canada K7L 3N6
    J Insect Physiol 58:1511-6. 2012
    ..We conclude that RCH preserves K(+) homeostasis in the fly brain during exposure to cold by reducing the temperature sensitivity of the rates of homeostatic processes...
  3. pmc Glial Hsp70 protects K+ homeostasis in the Drosophila brain during repetitive anoxic depolarization
    Gary A B Armstrong
    Department of Biology, Queen s University, Kingston, Ontario, Canada
    PLoS ONE 6:e28994. 2011
    ....
  4. doi Inhibition of protein kinase G activity protects neonatal mouse respiratory network from hyperthermic and hypoxic stress
    Gary A B Armstrong
    Department of Biology, Queen s University, Biosciences Complex, Kingston ON, Canada
    Brain Res 1311:64-72. 2010
    ..We propose that PKG activity inversely regulates the amount of stress the neonatal mammalian respiratory rhythm can endure...
  5. pmc Natural variation in the thermotolerance of neural function and behavior due to a cGMP-dependent protein kinase
    Ken Dawson-Scully
    University of Toronto, Department of Biology, Mississauga, Ontario, Canada
    PLoS ONE 2:e773. 2007
    ..PKG's role in thermotolerance may also apply to these and other species. Natural variation in thermotolerance arising from genes involved in the PKG pathway could impact the evolution of thermotolerance in natural populations...
  6. ncbi Suppression of spreading depression-like events in locusts by inhibition of the NO/cGMP/PKG pathway
    Gary A B Armstrong
    Department of Biology, Queen s University, Kingston, Ontario K7L 3N6, Canada
    J Neurosci 29:8225-35. 2009
    ..The highly conserved nature of the NO/cGMP/PKG signaling pathway suggests that it may be involved in modulating SD in other organisms, including mammals...
  7. doi Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS
    Gary A B Armstrong
    Department of Pathology and Cell Biology and Groupe de Recherche sur le Système Nerveux Central, Universite de Montreal, Montreal, QC, Canada H3C 3J7
    Hum Mol Genet 22:4282-92. 2013
    ..These results show that both a loss and gain of FUS function result in defective presynaptic function at the NMJ. ..
  8. doi Coma in response to environmental stress in the locust: a model for cortical spreading depression
    Corinne I Rodgers
    Department of Biology, Queen s University, Biosciences Complex, Kingston, Ontario, Canada
    J Insect Physiol 56:980-90. 2010
    ..We also suggest that locust SD-like events are adaptive by conserving energy and preventing cellular damage, and we provide a model for the mechanism of SD onset and recovery in the locust nervous system...
  9. pmc Stress preconditioning of spreading depression in the locust CNS
    Corinne I Rodgers
    Department of Biology, Queen s University, Biosciences Complex, Kingston, Ontario, Canada
    PLoS ONE 2:e1366. 2007
    ..We propose that they share mechanisms with CSD in mammals suggesting a common evolutionary origin...
  10. doi Metabolic stress modulates motor patterning via AMP-activated protein kinase
    Corinne I Rodgers-Garlick
    Department of Biology, Queen s University, Kingston, Ontario K7L 3N6, Canada
    J Neurosci 31:3207-16. 2011
    ..We show that the motor pattern changes induced by metabolic stress are not the result of SD alone, but that AMPK is necessary and sufficient for these changes and that AMPK activity strongly influences susceptibility to SD...
  11. ncbi Octopamine mediates thermal preconditioning of the locust ventilatory central pattern generator via a cAMP/protein kinase A signaling pathway
    Gary A B Armstrong
    Department of Biology, Queen s University, Kingston, Ontario, Canada K7L 3N6
    J Neurosci 26:12118-26. 2006
    ..We conclude that OA has a crucial role in triggering protein synthesis-dependent physiological adaptations to protect CNS function during heat stress by activating a cAMP/PKA pathway...