The role of activity, adherence, and off-loading on the healing of diabetic foot woundsStephanie C Wu
Scholl's Center for Lower Extremity Ambulatory Research (CLEAR) at Rosalind Franklin University of Medicine and Science, Chicago, Ill, USA
Plast Reconstr Surg 117:248S-253S. 2006
..This article reviews these data and suggests that an amalgam of effective pressure relief coupled with strategies to reduce nonadherence to this therapy could yield a potentially favorable clinical result...
- Toward a change in syntax in diabetic foot care: prevention equals remission
David G Armstrong
Southern Arizona Limb Salvage Alliance, Department of Surgery, University of Arizona College of Medicine, Tucson, AZ 85724, USA
J Am Podiatr Med Assoc 103:161-2. 2013
..This concept is easy for the patient and the rest of the team to understand. We believe that it powerfully connotes the necessity for frequent follow-up and rapid intervention for inevitable minor and sometimes major complications...
The impact and outcomes of establishing an integrated interdisciplinary surgical team to care for the diabetic footDavid G Armstrong
University of Arizona, Department of Surgery, Tucson, AZ 85724, USA
Diabetes Metab Res Rev 28:514-8. 2012
..This study aimed to quantify the impact of an integrated diabetic foot surgical service on outcomes and changes in surgical volume and focus...
- Use of negative pressure wound therapy to help facilitate limb preservation
David G Armstrong
Department of Surgery, University of Arizona College of Medicine, Tucson, AZ 85724, USA
Int Wound J 9:1-7. 2012
..This review merges scientific evidence with expert experience to show the role of negative pressure wound therapy using reticulated open cell foam (V.A.C.® Therapy, KCI USA, Inc., San Antonio, TX) in limb preservation...
- Comparative effectiveness of mechanically and electrically powered negative pressure wound therapy devices: a multicenter randomized controlled trial
David G Armstrong
Southern Arizona Limb Salvage Alliance, University of Arizona College of Medicine, Tuscon, 1501 N Campbell Avenue, Tucson, AZ 85724, USA
Wound Repair Regen 20:332-41. 2012
..Device related adverse events and complications such as infection were also similar between treatment groups. These data support similar wound healing outcomes between the SNaP system and the VAC system in the population studied...
Hydrodebridement of wounds: effectiveness in reducing wound bacterial contamination and potential for air bacterial contaminationFrank L Bowling
Department of Medicine Manchester Royal Infirmary, University of Manchester, Manchester, UK
J Foot Ankle Res 2:13. 2009
..The purpose of this study was to assess the level of air contamination with bacteria after surgical hydrodebridement and to determine the effectiveness of hydro surgery on bacterial reduction of a simulated infected wound...
- Nonlinear modeling of venous leg ulcer healing rates
Matthew Cardinal
Advanced BioHealing, La Jolla, CA, USA
BMC Dermatol 9:2. 2009
..The purpose of this manuscript was to determine whether the change in wound surface area over time could be described through nonlinear mathematics...
- Activity patterns of patients with diabetic foot ulceration: patients with active ulceration may not adhere to a standard pressure off-loading regimen
David G Armstrong
Department of Surgery, Southern Arizona Veterans Affairs Medical Center, Tucson, Arizona 85723, USA
Diabetes Care 26:2595-7. 2003
..To evaluate the activity of patients with diabetic foot ulcerations and their adherence to their pressure off-loading device...
- The diabetic rapid response acute foot team: 7 essential skills for targeted limb salvage
Ryan H Fitzgerald
Southern Arizona Limb Salvage Alliance and College of Medicine, University of Arizona, Tucson, USA
Eplasty 9:e15. 2009
..Recently, there has been increasing interest in the development of interdisciplinary teams to manage the myriad factors that complicate the treatment of high-risk patients, particularly in the perihospitalization period...
- Clinical efficacy of the first metatarsophalangeal joint arthroplasty as a curative procedure for hallux interphalangeal joint wounds in patients with diabetes
David G Armstrong
Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson, Arizona, USA
Diabetes Care 26:3284-7. 2003
..To evaluate the safety and efficacy of first metatarsophalangeal joint arthroplasty compared with standard, nonsurgical management of wounds at the plantar hallux interphalangeal joint in patients with diabetes...
- Classifying diabetic foot surgery: toward a rational definition
D G Armstrong
Department of Surgery, Southern Arizona Veterans Affairs Medical Center, Tucson, AZ 85723, USA
Diabet Med 20:329-31. 2003
..It is our hope that this system begins a dialogue amongst physicians and surgeons which can ultimately facilitate communication, enhance perspective, and improve care...
- Defining success in clinical trials of diabetic foot wounds: the Los Angeles DFCon consensus
David G Armstrong
Southern Arizona Limb Salvage Alliance, University of Arizona College of Medicine, Tucson, 85701, AZ, USA
Int Wound J 6:211-3. 2009
....
- Computerized activity monitoring preoperatively and postoperatively
David G Armstrong
Department of Surgery, Southern Arizona Veterans Affairs Medical Center, and the University of Arizona, Tucson, AZ, USA
J Foot Ankle Surg 43:131-3. 2004
..In this brief article, we describe our current experience with computerized activity monitoring. Use of modalities such as these may ultimately be able to monitor and dose levels of activity just as we do with a drug...
- Advances in the treatment of diabetic foot infections
David G Armstrong
Podiatry Section, Department of Surgery, Southern Arizona Veterans Affairs Medical Center, and University of Arizona, Tucson, Arizona 85750, USA
Diabetes Technol Ther 6:167-77. 2004
..g., antibiotic beads, impregnated sponges) and novel antibiotics (e.g., levofloxacin, linezolid) are providing possible solutions to the challenges posed by this physically, emotionally, and financially devastating condition...
- It's not what you put on, but what you take off: techniques for debriding and off-loading the diabetic foot wound
David G Armstrong
Department of Surgery, Dr William M Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA
Clin Infect Dis 39:S92-9. 2004
..Specific debridement and off-loading techniques are discussed, along with available supporting evidence. This includes the use of the "instant" total contact cast, among other modalities...
- Does dermal thermometry predict clinical outcome in diabetic foot infection? Analysis of data from the SIDESTEP* trial
David G Armstrong
Rosalind Franklin University, Chicago, IL, USA
Int Wound J 3:302-7. 2006
..While there was no overall relationship between skin temperature and poor clinical outcome, there may be a threshold effect in DT (<10 degrees F versus >10 degrees F) between the limbs at baseline that predicts outcome of therapy...
- Validation of a diabetic foot surgery classification
David G Armstrong
Scholl s Center for Lower Extremity Ambulatory Research at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA
Int Wound J 3:240-6. 2006
..This may assist the surgeon in better identifying risk when determining a rationale for and type of surgery in persons with diabetes...
- Diabetic foot infections: stepwise medical and surgical management
David G Armstrong
Dr William M Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, Chicago IL, USA
Int Wound J 1:123-32. 2004
..Most foot ulcers occur on the plantar surface of the foot, thus requiring a plantar incision for any drainage procedure...
- Negative pressure wound therapy via vacuum-assisted closure following partial foot amputation: what is the role of wound chronicity?
David G Armstrong
Scholl s Center for Lower Extremity Ambulatory Research, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA
Int Wound J 4:79-86. 2007
..These results appear to indicate that wound duration should not deter the clinician from using this modality to treat complex wounds...
- The pivotal role of offloading in the management of neuropathic foot ulceration
Stephanie C Wu
Dr William M Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60048, USA
Curr Diab Rep 5:423-9. 2005
..Combining an effective, easy to use offloading device that ensures patient compliance with advanced wound healing modalities may form a formidable team in healing ulcers and potentially averting lower limb amputations...
- Negative pressure wound therapy after partial diabetic foot amputation: a multicentre, randomised controlled trial
David G Armstrong
Scholl s Center for Lower Extremity Ambulatory Research CLEAR, Rosalind Franklin University of Medicine and Science, Chicago, IL 60064, USA
Lancet 366:1704-10. 2005
..We investigated whether negative pressure wound therapy (NPWT) improves the proportion and rate of wound healing after partial foot amputation in patients with diabetes...
- Skin temperature monitoring reduces the risk for diabetic foot ulceration in high-risk patients
David G Armstrong
Scholl s Center for Lower Extremity Ambulatory Research CLEAR, Rosalind Franklin University of Medicine and Science, North Chicago, Ill 60064, USA
Am J Med 120:1042-6. 2007
..To evaluate the effectiveness of home temperature monitoring to reduce the incidence of foot ulcers in high-risk patients with diabetes...
- Quality of life in healing diabetic wounds: does the end justify the means?
David G Armstrong
Scholl s Center for Lower Extremity Ambulatory Research CLEAR, Rosalind Franklin University of Medicine, Chicago, IL 60064, USA
J Foot Ankle Surg 47:278-82. 2008
..Specifically, the results suggest that in diabetic patients with neuropathic foot ulcers, QoL may have less to do with how an index wound is treated than it does with whether or not the wound heals...
- Can the use of a topical antifungal nail lacquer reduce risk for diabetic foot ulceration? Results from a randomised controlled pilot study
David G Armstrong
Scholl s Center for Lower Extremity Ambulatory Research CLEAR at Rosalind Franklin University of Medicine, 3333 Green Bay Road, Chicago, IL 60064, USA
Int Wound J 2:166-70. 2005
..The incidental finding of a potential reduction in hyperkeratosis and tinea pedis is a compelling one and may deserve further investigation...
- Evaluation of removable and irremovable cast walkers in the healing of diabetic foot wounds: a randomized controlled trial
David G Armstrong
Center for Lower Extremity Ambulatory Research, Dr William M Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, 3333 Green Bay Rd, North Chicago, IL 60064, USA
Diabetes Care 28:551-4. 2005
..The purpose of this study was to evaluate the effectiveness of a removable cast walker (RCW) and an "instant" total contact cast (iTCC) in healing neuropathic diabetic foot ulcerations...
- Classification of wounds of the diabetic foot
D G Armstrong
Department of Surgery, Southern Arizona Veterans Health Center, 3601 South Sixth Avenue, Tucson, AZ 85723, USA
Curr Diab Rep 1:233-8. 2001
....
- Lengthening of the Achilles tendon in diabetic patients who are at high risk for ulceration of the foot
D G Armstrong
Department of Orthopaedics, The University of Texas Health Science Center at San Antonio, 78284 7776, USA
J Bone Joint Surg Am 81:535-8. 1999
....
- Validation of a diabetic wound classification system. The contribution of depth, infection, and ischemia to risk of amputation
D G Armstrong
Department of Orthopaedics, University of Texas Health Science Center, San Antonio, Texas 7703, USA
Diabetes Care 21:855-9. 1998
..To validate a wound classification instrument that includes assessment of depth, infection, and ischemia based on the eventual outcome of the wound...
- Factors associated with bone regrowth following diabetes-related partial amputation of the foot
D G Armstrong
Department of Orthopaedics, University of Texas Health Science Center at San Antonio, 78284 7776, USA
J Bone Joint Surg Am 81:1561-5. 1999
..However, we are not aware of previous studies evaluating the risk factors for this entity...
- Improvement in healing with aggressive edema reduction after debridement of foot infection in persons with diabetes
D G Armstrong
Department of Surgery, Southern Arizona Veterans Affairs Medical Center, 3601 S Sixth Ave, Tucson, AZ, USA
Arch Surg 135:1405-9. 2000
..Nonhealing foot wounds are the major precipitant of lower-extremity amputation in the diabetic population...
- Off-loading the diabetic foot wound: a randomized clinical trial
D G Armstrong
Audie L Murphy Veterans Affairs Medical Center, Tucson, AZ 85723, USA
Diabetes Care 24:1019-22. 2001
..To compare the effectiveness of total-contact casts (TCCs), removable cast walkers (RCWs), and half-shoes to heal neuropathic foot ulcerations in individuals with diabetes...
- Elevated peak plantar pressures in patients who have Charcot arthropathy
D G Armstrong
Department of Orthopaedics, The University of Texas Health Science Center at San Antonio, 78284 7776, USA
J Bone Joint Surg Am 80:365-9. 1998
..Although the midfoot was the site of maximum involvement in all patients who had Charcot arthropathy, the peak plantar pressure was on the forefoot, suggesting that the forefoot may function as a lever, forcing collapse in the midfoot...
- Peak foot pressures influence the healing time of diabetic foot ulcers treated with total contact casts
D G Armstrong
Department of Orthopaedics, University of Texas Health Science Center, San Antonio 78284, USA
J Rehabil Res Dev 35:1-5. 1998
..2 +/- 26.2 vs. 29.9 +/- 10.6 days, P = 0.02). We conclude that subjects with high plantar pressures and wounds greater than 8 cm2 took significantly longer to heal when uniformly treated with TCC...
- Is diabetic foot care efficacious or cost effective?
D G Armstrong
Department of Surgery, Southern Arizona Veterans Affairs Medical Center, 3601 South Sixth Avenue, Tucson, AZ 85723, USA
Ostomy Wound Manage 47:28-32. 2001
....
- Outcomes of subatmospheric pressure dressing therapy on wounds of the diabetic foot
David G Armstrong
Department of Surgery, Southern Arizona Veterans Affairs Medical Center, Tucson, Ariz, USA
Ostomy Wound Manage 48:64-8. 2002
....
- Diagnostics, theragnostics, and the personal health server: fundamental milestones in technology with revolutionary changes in diabetic foot and wound care to come
David G Armstrong
Southern Arizona Limb Salvage Alliance, University of Arizona College of Medicine, Tucson, Arizona, USA
Foot Ankle Spec 4:54-60. 2011
..The authors believe that devices will be organized into personal health servers in cloud-synchronized devices already existing in the home (eg, a scale), the clinic, and on (or in) the patient...
- Comparison of negative pressure wound therapy with an ultraportable mechanically powered device vs. traditional electrically powered device for the treatment of chronic lower extremity ulcers: a multicenter randomized-controlled trial
David G Armstrong
Southern Arizona Limb Salvage Alliance, University of Arizona College of Medicine, Tuscon, Arizona, USA
Wound Repair Regen 19:173-80. 2011
..05 significance level (*p=0.019). These interim data suggest no difference in wound closure between the SNaP(®) System and the VAC(®) System in the population studied. We look forward to the final analysis results...
- Variability in activity may precede diabetic foot ulceration
David G Armstrong
Dr William M Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, Chicago, Illinois 60064, USA
Diabetes Care 27:1980-4. 2004
..To evaluate the role of activity in the development of neuropathic foot ulceration in individuals with diabetes...
- Monitoring healing of acute Charcot's arthropathy with infrared dermal thermometry
D G Armstrong
Department of Orthopaedics, University of Texas Health Science Center, San Antonio 78284 7776, USA
J Rehabil Res Dev 34:317-21. 1997
..Temperatures decreased in a predictable manner as acute arthropathy resolved. Additionally, increased temperature gradients may be predictive of future ulceration...
- An overview of foot infections in diabetes
David G Armstrong
Department of Surgery, University of Arizona College of Medicine, Tucson, Arizona 85724 5072, USA
Diabetes Technol Ther 13:951-7. 2011
....
- Electric stimulation as an adjunct to heal diabetic foot ulcers: a randomized clinical trial
E J Peters
Mexican American Medical Treatment Effectiveness Research Center, Department of Orthopaedics, University of Texas Health Sciences Center, San Antonio, TX, USA
Arch Phys Med Rehabil 82:721-5. 2001
..32, p = .038). There was no significant difference in compliance between the 2 groups. CONCLUSION: Electric simulation enhances wound healing when used in conjunction with appropriate off-loading and local wound care...
- Functional status of persons with diabetes-related lower-extremity amputations
E J Peters
Department of Orthopedics, University of Texas Health Science Center, San Antonio, Texas, USA
Diabetes Care 24:1799-804. 2001
..The objective of this study was to evaluate amputations among diabetic patients and to determine the functional level of these patients with the Sickness Impact Profile (SIP)...
- Reducing plantar pressure in the neuropathic foot. A comparison of footwear
L A Lavery
Department of Orthopedics, University of Texas Health Science Center, San Antonio 78284 7776, USA
Diabetes Care 20:1706-10. 1997
..To compare the effectiveness of therapeutic, comfort, and athletic shoes with and without viscoelastic insoles...
- Plantar pressure changes using a novel negative pressure wound therapy technique
David G Armstrong
Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson, USA
J Am Podiatr Med Assoc 94:456-60. 2004
....
- Reliability of digital videometry and acetate tracing in measuring the surface area of cutaneous wounds
R P Wunderlich
Department of Orthopaedics, The University of Texas Health Science Center at San Antonio, 10022 Tezel Road, San Antonio, TX 78250, USA
Diabetes Res Clin Pract 49:87-92. 2000
..The purpose of this study was to evaluate the reliability of digital videometry and acetate tracing in the measurement of cutaneous wound area...
- The forefoot-to-rearfoot plantar pressure ratio is increased in severe diabetic neuropathy and can predict foot ulceration
Antonella Caselli
Joslin Beth Israel Deaconess Foot Center, Harvard Medical School, Department of Surgery, Boston, Massachusetts 02215, USA
Diabetes Care 25:1066-71. 2002
..This may lend further evidence toward the concept that equinus develops in the latest stages of peripheral neuropathy and may play an important role in the etiology of diabetic foot ulceration...
- Continuous activity monitoring in persons at high risk for diabetes-related lower-extremity amputation
D G Armstrong
Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson, AZ, USA
J Am Podiatr Med Assoc 91:451-5. 2001
..The ability to continuously monitor the magnitude, duration, and time of activity ultimately may assist clinicians in dosing activity just as they dose drugs...
- Wound inflammatory index: a "proof of concept" study to assess wound healing trajectory
Manish Bharara
Southern Arizona Limb Salvage Alliance SALSA, College of Medicine, University of Arizona, Tucson, Arizona 85724, USA
J Diabetes Sci Technol 4:773-9. 2010
..In this single case study, the TI/wound inflammatory index indicates a shift from negative to positive (p < .05) before it reaches zero...
- Validation of the Infectious Diseases Society of America's diabetic foot infection classification system
Lawrence A Lavery
Department of Surgery, Scott and White Hospital, Texas A and M University Health Science Center College of Medicine, Temple, Texas, USA
Clin Infect Dis 44:562-5. 2007
..6; P<.001) with increasing infection severity. The Infectious Diseases Society of America's foot infection classification system may be a useful tool for grading foot infections...
- A step-wise approach for surgical management of diabetic foot infections
Timothy K Fisher
Southern Arizona Limb Salvage Alliance, Department of Surgery, University of Arizona College of Medicine, Tucson, AZ 85724, USA
J Vasc Surg 52:72S-75S. 2010
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- Preventing diabetic foot ulcer recurrence in high-risk patients: use of temperature monitoring as a self-assessment tool
Lawrence A Lavery
Department of Surgery, Scott and White Hospital, Texas A and M University Health Science Center, Temple, Texas, USA
Diabetes Care 30:14-20. 2007
..The purpose of this study was to evaluate the effectiveness of a temperature monitoring instrument to reduce the incidence of foot ulcers in individuals with diabetes who have a high risk for lower extremity complications...
- Practical criteria for screening patients at high risk for diabetic foot ulceration
L A Lavery
Department of Orthopaedics, University of Texas Health Science Center at San Antonio, USA
Arch Intern Med 158:157-62. 1998
..A comprehensive understanding of clinical risk factors for developing foot ulcerations would help clinicians to categorize patients by their risk status and schedule intervention resources accordingly to prevent amputation...
- Update from the Diabetic Foot Global Conference (DFCon) 2007
Lee C Rogers
Center for Lower Extremity Ambulatory Research, Chicago, IL, USA
Int Wound J 4:295-7. 2007
- Do US veterans wear appropriately sized shoes?: the Veterans Affairs shoe size selection study
Brent P Nixon
Department of Surgery, Southern Arizona Veterans Affairs Medical Center, Tucson, USA
J Am Podiatr Med Assoc 96:290-2. 2006
..This implies that appropriate meticulous screening for shoe-foot mismatches may be useful in reducing the risk of lower-extremity ulceration...
- Negative pressure wound therapy in treatment of diabetic foot wounds: a marriage of modalities
David G Armstrong
Department of Surgery, Podiatry Section, Tucson Veterans Administration Hospital, Ariz, USA
Ostomy Wound Manage 50:9-12. 2004
- Probe-to-bone test for diagnosing diabetic foot osteomyelitis: reliable or relic?
Lawrence A Lavery
Department of Surgery, Scott and White Hospital, 703 Highland Spring Lane, Georgetown, TX 78628, USA
Diabetes Care 30:270-4. 2007
..We sought to assess the accuracy of the probe-to-bone (PTB) test in diagnosing foot osteomyelitis in a cohort of diabetic patients with bone culture proven disease...
- A method for assessing off-loading compliance
Ryan T Crews
Scholl s Center for Lower Extremity Ambulatory Research CLEAR at Rosalind Franklin University of Medicine and Science, Chicago, IL 60064, USA
J Am Podiatr Med Assoc 99:100-3. 2009
..However, many patients are not compliant in using prescribed footwear or off-loading devices. We sought to validate a method of objectively measuring off-loading compliance via activity monitors...
- Use of a Nanoflex powder dressing for wound management following debridement for necrotising fasciitis in the diabetic foot
Ryan H Fitzgerald
Southern Arizona Limb Salvage Alliance SALSA, Department of Surgery, College of Medicine, University of Arizona, Tucson, AZ 85724 5072, USA
Int Wound J 6:133-9. 2009
....
- Diabetic lower extremity infection: influence of physical, psychological, and social factors
Edgar J G Peters
Department of Internal Medicine, Haga Hospital, Leyenburg, The Hague, The Netherlands
J Diabetes Complications 19:107-12. 2005
..The purpose of this study was to identify local, systemic, and psychosocial risk factors that can lead to severe foot infections and subsequent amputations...
- The combined hammer toe-mallet toe deformity with associated double corns: a retrospective review
T P Oliver
Department of Orthopaedics Podiatry, The University of Texas Health Science Center at San Antonio, USA
Clin Podiatr Med Surg 13:263-8. 1996
..This article reviews 20 patients undergoing 62 double resectional arthroplasty procedures for treatment of the deformity...
- Foot ulcers in the diabetic patient, prevention and treatment
Stephanie C Wu
Center for Lower Extremity Ambulatory Research, William M Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, Chicago, IL 60048, USA
Vasc Health Risk Manag 3:65-76. 2007
..Early recognition of the etiological factors along with prompt management of diabetic foot ulcers is essential for successful outcome...
- Use of chlorhexidine-impregnated patch at pin site to reduce local morbidity: the ChIPPS Pilot Trial
Stephanie C Wu
Scholl s Center for Lower Extremity Ambulatory Research CLEAR, Rosalind Franklin University of Medicine, Chicago, IL 60064, USA
Int Wound J 5:416-22. 2008
..The results of this initial study suggest that chlorhexidine gluconate-impregnated polyurethane dressing may be effective to reduce the incidence of pin tract infections and help decrease morbidity associated with external fixation...
- CLEAR Cleat: a proof-of-concept trial of an aerobic activity facilitator to reduce plantar forefoot pressures and their potential in those with foot ulcers
Erin E Klein
Scholl s Center for Lower Extremity Ambulatory Research CLEAR, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA
J Am Podiatr Med Assoc 98:261-7. 2008
..The purpose of this project was to demonstrate a device that reduces cycling plantar forefoot pressure...
- Diabetic foot infections: A need for innovative assessments
Timothy K Fisher
University of Arizona, Tucson, 85724, USA
Int J Low Extrem Wounds 9:31-6. 2010
..Adopting these advances in diagnosis and treatment may help with overall prognosis and reduce health care costs...
- Novel use of insulin in continuous-instillation negative pressure wound therapy as "wound chemotherapy"
Christy L Scimeca
Southern Arizona Limb Salvage Alliance SALSA, College of Medicine, University of Arizona, Tucson, Arizona 85724, USA
J Diabetes Sci Technol 4:820-4. 2010
..We present a case report in which insulin was used as a chemotherapeutic agent in continuous-instillation NPWT. To our knowledge, this is the first report in the literature describing this method of delivery...
- Outcomes of hyaluronan therapy in diabetic foot wounds
J R Vazquez
Department of Surgery, Southern Arizona Veterans Affairs Health Center, 3601 South Sixth Avenue, Tucson 85723, USA
Diabetes Res Clin Pract 59:123-7. 2003
..We await the completion of a multicenter randomized controlled trial in this area to either support or refute this initial assessment...
- What is the shelf life of physician-mixed antibiotic-impregnated calcium sulfate pellets?
David G Armstrong
Department of Surgery, Southern Arizona Veterans Affairs Health Care System, Tucson, AZ 85723, USA
J Foot Ankle Surg 42:302-4. 2003
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- Diabetic foot syndrome: evaluating the prevalence and incidence of foot pathology in Mexican Americans and non-Hispanic whites from a diabetes disease management cohort
Lawrence A Lavery
Department of Surgery, Diabetex Research Group, Baltimore, Maryland, USA
Diabetes Care 26:1435-8. 2003
..To report the incidence of diabetes-related lower-extremity complications in a cohort of patients enrolled in a diabetes disease management program...
- Technique for fabrication of an "instant total-contact cast" for treatment of neuropathic diabetic foot ulcers
David G Armstrong
Research and Education, Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson 85723, USA
J Am Podiatr Med Assoc 92:405-8. 2002
..In the authors' opinion, this technique addresses many of the disadvantages of the total-contact cast, resulting in an adequate compromise in this aspect of care...
- Maggot debridement therapy: a primer
David G Armstrong
Research and Education, Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson 85723, USA
J Am Podiatr Med Assoc 92:398-401. 2002
..This article describes the use of maggot debridement therapy for intractable wounds of the lower extremity...
- Guidelines regarding negative wound therapy (NPWT) in the diabetic foot
David G Armstrong
Department of Surgery, Southern Arizona Veterans Affairs Medical Center, Tucson, USA
Ostomy Wound Manage 50:3S-27S. 2004
..NPWT be discontinued in this population? 8) How should NPWT be used in combination with other modalities? 9) Should small, superficial, noninfected wounds be considered for NPWT? 10) How should we define success in future studies of NPWT?..
- Can we predict outcome of surgical reconstruction of Charcot neuroarthropathy by dynamic plantar pressure assessment?--A proof of concept study
Bijan Najafi
Scholl s Center for Lower Extremity Ambulatory Research, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA
Gait Posture 31:87-92. 2010
..55), suggesting that RF value is independent of gait speed. In preoperative Charcot patients, the RF<0, however, RF increased post-surgery (RF=0.42), indicating a transition to normal plantar distribution after Charcot reconstruction...
- Maggot therapy in "lower-extremity hospice" wound care: fewer amputations and more antibiotic-free days
David G Armstrong
Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson, AZ, USA
J Am Podiatr Med Assoc 95:254-7. 2005
..8 +/- 30.3 versus 81.9 +/- 42.1 days). Maggot debridement therapy reduces short-term morbidity in nonambulatory patients with diabetic foot wounds...
- Cooling the foot to prevent diabetic foot wounds: a proof-of-concept trial
David G Armstrong
Department of Surgery, Southern Arizona Veterans Affairs Medical Center, Tucson, USA
J Am Podiatr Med Assoc 95:103-7. 2005
..No adverse effects resulted from the intervention. We conclude that cooling the foot may be a safe and effective method of reducing inflammation and may serve as a prophylactic or interventional tool to reduce skin breakdown risk...
- Clinical outcome of diabetic foot ulcers treated with negative pressure wound therapy and the transition from acute care to home care
Stephanie C Wu
Department of Surgery, Dr William M Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, Center for Lower Extremity Ambulatory Research, 3333 Green Bay Road, North Chicago, IL 60048, USA
Int Wound J 5:10-6. 2008
..Resources need to be combined in a collaborative and synergistic fashion to allow patient to perform many daily living activities while receiving the potential benefits of an advanced wound healing modality...
- Use of a maggot motility index to evaluate survival of therapeutic larvae
Anthony Rosales
Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson, USA
J Am Podiatr Med Assoc 94:353-5. 2004
..There were significant differences in motility between refrigerated and nonrefrigerated larvae immediately after baseline until day 8. Larvae are more practical for repeated clinical use if kept refrigerated between applications...
- Efficacy of fifth metatarsal head resection for treatment of chronic diabetic foot ulceration
David G Armstrong
Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson, USA
J Am Podiatr Med Assoc 95:353-6. 2005
..5% versus 27.8%). The results of this study suggest that fifth metatarsal head resection is a potentially effective treatment in patients at high risk of ulceration and reulceration...
- Gamma-irradiated human skin allograft: a potential treatment modality for lower extremity ulcers
M Anthony Rosales
Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson, AZ, USA
Int Wound J 1:201-6. 2004
..In this article, we present case studies with concise reviews of the available evidence to discuss the potential use of gamma-irradiated human skin allograft on wounds in the lower extremity...
- Use of clinical laboratory parameters to evaluate wound healing potential in diabetes mellitus
Patricia L Abu-Rumman
Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson, AZ, USA
J Am Podiatr Med Assoc 92:38-47. 2002
..This article provides a practical format to assist clinicians in better evaluating this often difficult-to-assess area of care...
- How and why to surgically debride neuropathic diabetic foot wounds
David G Armstrong
Research and Education, Department of Surgery, Podiatry Section, Southern Arizona Veterans Affairs Medical Center, Tucson 85723, USA
J Am Podiatr Med Assoc 92:402-4. 2002
..The authors hope to foster further discussion leading to improvement in the process and the prevalence of such debridement...
- Risk assessment of the diabetic foot and wound
Stephanie Wu
Dr William M. Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA
Int Wound J 2:17-24. 2005
..This manuscript will discuss these key risk factors and briefly outline steps for simple, evidence-based assessment of risk in this population...
- Risk factors for developing osteomyelitis in patients with diabetic foot wounds
Lawrence A Lavery
Department of Surgery, Scott and White Hospital, Texas A and M University Health Science Center College of Medicine, Temple, TX, USA
Diabetes Res Clin Pract 83:347-52. 2009
..Osteomyelitis worsens the prognosis in the diabetic foot, but predisposing factors remain largely undefined. In a prospectively followed cohort we assessed risk factors for developing osteomyelitis...
- Wound care: the role of advanced wound healing technologies
Stephanie C Wu
Rosalind Franklin University of Medicine and Science, North Chicago, Ill, USA
J Vasc Surg 52:59S-66S. 2010
....
- Prediction of healing for postoperative diabetic foot wounds based on early wound area progression
Lawrence A Lavery
Department of Surgery, Scott and White Memorial Hospital at Texas A and M University, Georgetown, Texas, USA
Diabetes Care 31:26-9. 2008
..To evaluate the probability of wound healing based on percentage of wound area reduction (PWAR) at 1 and 4 weeks in individuals with large, chronic, nonischemic diabetic foot wounds following partial foot amputation...
- Chronic, painful lower extremity wounds: postoperative pain management through the use of continuous infusion of regional anaesthesia supplied by a portable pump device
Christy L Scimeca
Southern Arizona Limb Salvage Alliance SALSA, Department of Surgery, University of Arizona College of Medicine, Tucson, AZ 85741, USA
Int Wound J 7:195-8. 2010
..The device provided sufficient analgesia to the patient without any observed adverse effects, and showed significant potential in avoiding an increase in his requirement for other systemic analgesia including opioids...
- Use of pressure offloading devices in diabetic foot ulcers: do we practice what we preach?
Stephanie C Wu
Scholl s Center for Lower Extremity Ambulatory Research, Rosalind Franklin Universityof Medicine and Science, North Chicago, Illinois, USA
Diabetes Care 31:2118-9. 2008
..Pressure mitigation is crucial for the healing of plantar diabetic foot ulcers. We therefore discuss characteristics and considerations associated with the use of offloading devices...
- The micrograft concept for wound healing: strategies and applications
Atanu Biswas
College of Medicine, Department of Surgery, Center for Cellular Transplantation, University of Arizona, Tucson, Arizona 85724, USA
J Diabetes Sci Technol 4:808-19. 2010
..The physiological concept of micrografting, along with historical context, and the evolution of the technique are discussed, as well as studies needed for micrograft characterization and future applications of the technique...
- Risk factors for foot infections in individuals with diabetes
Lawrence A Lavery
Department of Surgery, Scott and White Hospital, Texas A and M University Health Science Center College of Medicine, Temple, TX, USA
Diabetes Care 29:1288-93. 2006
..To prospectively determine risk factors for foot infection in a cohort of people with diabetes...
- The role of interdisciplinary team approach in the management of the diabetic foot: a joint statement from the Society for Vascular Surgery and the American Podiatric Medical Association
Bauer E Sumpio
Department of Surgery, Yale University School of Medicine, New Haven, CT 06520, USA
J Am Podiatr Med Assoc 100:309-11. 2010
....
- Offloading diabetic foot wounds using the scotchcast boot: a retrospective study
E Ann Knowles
Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK
Ostomy Wound Manage 48:50-3. 2002
....
- Risk factors for recurrent diabetic foot ulcers: site matters
Edgar J G Peters
Department of Infectious Diseases, C5-P, Leiden University Medical Center, P.O. Box 9600, NL-2300RC, Leiden, The Netherlands
Diabetes Care 30:2077-9. 2007
- Clinical predictors of treatment failure for diabetic foot infections: data from a prospective trial
Benjamin A Lipsky
Veterans Affairs Puget Sound Health Care System, University of Washington School of Medicine, Seattle, WA 98108 1597, USA
Int Wound J 4:30-8. 2007
..Increased white blood cell count and severe UT wound grade at baseline, but not other features, were significant independent and additive risk factors for clinical failure in patients treated for a diabetic foot infection...
- Home monitoring of foot skin temperatures to prevent ulceration
Lawrence A Lavery
College of Medicine, Texas A and M Health Science Center, Scott and White Hospital, Temple, Texas, USA
Diabetes Care 27:2642-7. 2004
..To evaluate the effectiveness of at-home infrared temperature monitoring as a preventative tool in individuals at high risk for diabetes-related lower-extremity ulceration and amputation...
- Talactoferrin alfa, a recombinant human lactoferrin promotes healing of diabetic neuropathic ulcers: a phase 1/2 clinical study
Thomas E Lyons
Beth Israel Deaconess Medical Center and Harvard Medical School, Palmer 321 A, West Campus, Boston, MA 02215, USA
Am J Surg 193:49-54. 2007
..Talactoferrin alfa, a recombinant form of human lactoferrin, is a novel immunomodulatory protein with demonstrated ulcer healing properties in animal models...
- Use of subatmospheric (VAC) therapy to improve bioengineered tissue grafting in diabetic foot wounds
Eric H Espensen
Diabetic Foot Center, Providence St Joseph Medical Center, Burbank, CA, USA
J Am Podiatr Med Assoc 92:395-7. 2002
..Future descriptive and analytic works may test the hypothesis that combined therapies used at different and often overlapping periods during the wound-healing cycle may be more effective than a single modality...
- The effect of silicone injections in the diabetic foot on peak plantar pressure and plantar tissue thickness: a 2-year follow-up
Carine H van Schie
Department of Medicine, Manchester Royal Infirmary, University of Manchester, UK
Arch Phys Med Rehabil 83:919-23. 2002
..To report the efficacy of injected liquid silicone (ILS) in the foot at 2 years after administration...
- Consensus statement on negative pressure wound therapy (V.A.C. Therapy) for the management of diabetic foot wounds
George Andros
Diabetic Foot Center, Providence Saint Joseph Medical Center, Burbank, CA, USA
Ostomy Wound Manage . 2006
..A.C. Therapy? (11) How should success in the use of V.A.C. Therapy be defined? (12) How can one combine effective offloading and V.A.C. Therapy?..
- The Diabetic Foot 2001. A summary of the proceedings of the American Diabetes Association's 61st Scientific Symposium
Robert G Frykberg
College of Podiatric Medicine and Surgery, Des Moines University, 3200 Grand Ave, Des Moines, IA 50312, USA
J Am Podiatr Med Assoc 92:2-6. 2002
..Many of the issues raised at the meeting will form building blocks for future research into offloading, footwear, wound classification, wound healing, tissue engineering, and psychological aspects of therapy and prevention...
- Efficacy and safety of neutral pH superoxidised solution in severe diabetic foot infections
Fermín R Martínez-De Jesús
Diabetic Foot Salvage and Prevention Center San Elian, Veracruz, Ver, Academia Mexicana de Cirugia, International Working Group on the Diabetic Foot, Mexico
Int Wound J 4:353-62. 2007
..2%; P < 0.01). A non toxic, NpHSS, as part of a comprehensive care regimen, may be more efficacious in infection control, odour and erythema reduction than conventional disinfectants in treatment of diabetic foot infections...
- Ankle equinus deformity and its relationship to high plantar pressure in a large population with diabetes mellitus
Lawrence A Lavery
Diabetex Research Group, Baltimore, Maryland, USA
J Am Podiatr Med Assoc 92:479-82. 2002
..Having a high index of suspicion for this deformity and subsequently addressing it through conservative or surgical means may help to reduce the risk of foot ulceration and amputation...
- Comprehensive foot examination and risk assessment: a report of the task force of the foot care interest group of the American Diabetes Association, with endorsement by the American Association of Clinical Endocrinologists
Andrew J M Boulton
Manchester Diabetes Centre, Manchester, UK
Diabetes Care 31:1679-85. 2008
