Susana Puntarulo

Summary

Affiliation: Universidad de Buenos Aires
Country: Argentina

Publications

  1. ncbi UV-B effects on Antarctic Chlorella sp cells
    M S Estevez
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina
    J Photochem Photobiol B 62:19-25. 2001
  2. ncbi Forms of iron binding in the cells and the chemical features of chelation therapy
    S Puntarulo
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
    Mini Rev Med Chem 9:1136-46. 2009
  3. ncbi Iron, oxidative stress and human health
    Susana Puntarulo
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, 1113 Buenos Aires, Argentina
    Mol Aspects Med 26:299-312. 2005
  4. ncbi Iron and radical content in Mya arenaria. Possible sources of NO generation
    Paula Mariela González
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, 1113 Buenos Aires, Argentina
    Aquat Toxicol 89:122-8. 2008
  5. ncbi Ferritin-dependent radical generation in rat liver homogenates
    Ivan Rousseau
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, Junin 956, C1113AAD, Buenos Aires, Argentina
    Toxicology 264:155-61. 2009
  6. ncbi Iron and nitrosative metabolism in the Antarctic mollusc Laternula elliptica
    Paula Mariela González
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, 1113 Buenos Aires, Argentina
    Comp Biochem Physiol C Toxicol Pharmacol 153:243-50. 2011
  7. ncbi Fe allocation in liver during early stages of endotoxemia in Fe-overload rats
    Ivan Rousseau
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, Buenos Aires, Argentina
    Toxicol Pathol 39:1075-83. 2011
  8. ncbi Exposure to nitric oxide protects against oxidative damage but increases the labile iron pool in sorghum embryonic axes
    Sebastián Jasid
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, Buenos Aires, C1113AAD, Argentina
    J Exp Bot 59:3953-62. 2008
  9. ncbi Exposure to nitric oxide increases the nitrosyl-iron complexes content in sorghum embryonic axes
    Marcela Simontacchi
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, Buenos Aires 1113, Argentina
    Plant Sci 183:159-66. 2012
  10. ncbi Soybean ferritin: isolation, characterization, and free radical generation
    Andrea Galatro
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires C1113AAD, Argentina
    J Integr Plant Biol 54:45-54. 2012

Collaborators

Detail Information

Publications31

  1. ncbi UV-B effects on Antarctic Chlorella sp cells
    M S Estevez
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina
    J Photochem Photobiol B 62:19-25. 2001
    ..Moreover, a significant decrease in the content of both lipid and water soluble antioxidants might contribute to establish oxidative stress in the cells...
  2. ncbi Forms of iron binding in the cells and the chemical features of chelation therapy
    S Puntarulo
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
    Mini Rev Med Chem 9:1136-46. 2009
    ..This work reviews the main features of Fe binding in the cell and its association to these processes. The chemical nature of the Fe extracted by chelation therapy in pathophysiological situations is also analyzed...
  3. ncbi Iron, oxidative stress and human health
    Susana Puntarulo
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, 1113 Buenos Aires, Argentina
    Mol Aspects Med 26:299-312. 2005
    ....
  4. ncbi Iron and radical content in Mya arenaria. Possible sources of NO generation
    Paula Mariela González
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, 1113 Buenos Aires, Argentina
    Aquat Toxicol 89:122-8. 2008
    ..16+/-0.06 pmol/(mg FW min). The data presented here document the detectable presence of highly reactive species in M. arenaria...
  5. ncbi Ferritin-dependent radical generation in rat liver homogenates
    Ivan Rousseau
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, Junin 956, C1113AAD, Buenos Aires, Argentina
    Toxicology 264:155-61. 2009
    ..The data in tissue homogenates presented here showed that radical generation is associated to FER Fe release, and moreover that the FER protein itself was affected during this process...
  6. ncbi Iron and nitrosative metabolism in the Antarctic mollusc Laternula elliptica
    Paula Mariela González
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, 1113 Buenos Aires, Argentina
    Comp Biochem Physiol C Toxicol Pharmacol 153:243-50. 2011
    ..elliptica might contribute to restrict oxidative damage by a close link with Fe metabolism...
  7. ncbi Fe allocation in liver during early stages of endotoxemia in Fe-overload rats
    Ivan Rousseau
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, Buenos Aires, Argentina
    Toxicol Pathol 39:1075-83. 2011
    ....
  8. ncbi Exposure to nitric oxide protects against oxidative damage but increases the labile iron pool in sorghum embryonic axes
    Sebastián Jasid
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, Buenos Aires, C1113AAD, Argentina
    J Exp Bot 59:3953-62. 2008
    ....
  9. ncbi Exposure to nitric oxide increases the nitrosyl-iron complexes content in sorghum embryonic axes
    Marcela Simontacchi
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, Buenos Aires 1113, Argentina
    Plant Sci 183:159-66. 2012
    ..Moreover, demonstrate the presence of MNICs as one of the important components of the LIP, which could actively participate in Fe cellular mobilization...
  10. ncbi Soybean ferritin: isolation, characterization, and free radical generation
    Andrea Galatro
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires C1113AAD, Argentina
    J Integr Plant Biol 54:45-54. 2012
    ..Moreover, the scavenging of these radicals by Ft itself could then lead to protein damage. However, Ft could also prevent cellular damage by the uptake of catalytically active Fe...
  11. ncbi Exposure to excess dissolved iron in vivo affects oxidative status in the bivalve Mya arenaria
    Paula M Gonzalez
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, 1113 Buenos Aires, Argentina
    Comp Biochem Physiol C Toxicol Pharmacol 152:167-74. 2010
    ..Moreover, the second phase could be understood as the consequence of the exhaustion of cellular protective systems that could also involve NO...
  12. ncbi In vivo supplementation with Ginkgo biloba protects membranes against lipid peroxidation
    Alejandro D Boveris
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina
    Phytother Res 21:735-40. 2007
    ..The data presented here showed that Gb extracts were able to limit lipid peroxidation and scavenge lipid radicals in vivo and actively protect membranes from oxidative damage...
  13. ncbi Early neuroprotective effect of nitric oxide in developing rat brain irradiated in utero
    Pablo Gisone
    Laboratorio de Radiopatología, Autoridad Regulatoria Nuclear, Buenos Aires, Argentina
    Neurotoxicology 24:245-53. 2003
    ..Thus, increased NO steady-state concentration could be ascribed to an increase in NOS activity. Taken as a whole, these results suggest that NO might act to protect the developing brain from the cytotoxicity of reactive species...
  14. ncbi Labile iron pool and ferritin content in developing rat brain gamma-irradiated in utero
    Elizabeth Robello
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
    Neurotoxicology 30:430-5. 2009
    ..The data presented in this work are the first experimental evidence suggesting that, as part of the network of the cellular response to limit irradiation-dependent injury, a complex interaction between Fe and NO could be triggered...
  15. ncbi New insights on dimethylaminoethanol (DMAE) features as a free radical scavenger
    Gabriela Malanga
    Fisicoquímica, Facultad de Farmacia y Bioquimica, Junin 956, 1113 Buenos Aires, Argentina
    Drug Metab Lett 6:54-9. 2012
    ..DMAE ability to directly react with hydroxyl, ascorbyl and lipid radicals was tested employing in vitro assays, and related to the supplemented dose of the compound...
  16. ncbi Liver preconditioning induced by iron in a rat model of ischemia/reperfusion
    Monica Galleano
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires CONICET, Buenos Aires, Argentina
    Life Sci 89:221-8. 2011
    ....
  17. ncbi Nitric oxide and iron: effect of iron overload on nitric oxide production in endotoxemia
    Monica Galleano
    Physical Chemistry-PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, C1113AAD Buenos Aires, Argentina
    Mol Aspects Med 25:141-54. 2004
    ..Further studies will be required to assess the complex role of the Kupffer cells on iNOS induction and NO production...
  18. ncbi Does hepatomegaly alter iron-dependent oxidative effects in human plasma?
    Monica Galleano
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina
    Hum Exp Toxicol 22:401-5. 2003
    ..The data presented here suggest that abnormal liver condition affects iron-dependent oxidative stress in plasma. Moreover, alpha-T does not seem to be the main antioxidant to control iron-dependent oxidative stress in plasma...
  19. ncbi Lipid radical generation in polar (Laternula elliptica) and temperate (Mya arenaria) bivalves
    Maria Susana Estevez
    Physical Chemistry-PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, , 1113, Buenos Aires, Argentina
    Comp Biochem Physiol B Biochem Mol Biol 132:729-37. 2002
    ..L. elliptica had a higher content of alpha-tocopherol and beta-carotene than M. arenaria. Our data suggest that increased lipid radical content in the membranes of cold-adapted organisms could be related to iron content...
  20. ncbi Ascorbyl radical/ascorbate ratio in plasma from iron overloaded rats as oxidative stress indicator
    Monica Galleano
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, Argentina
    Toxicol Lett 133:193-201. 2002
    ..On this regard, evaluation of A*/AH(-) ratio did not help to discriminate between the possible involved mechanisms...
  21. ncbi Chloroplasts as a nitric oxide cellular source. Effect of reactive nitrogen species on chloroplastic lipids and proteins
    Sebastián Jasid
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
    Plant Physiol 142:1246-55. 2006
    ..Data reported here suggest that NO is an endogenous metabolite in soybean chloroplasts and that reactive nitrogen species could exert either antioxidant or prooxidant effects on chloroplast macromolecules...
  22. ncbi A kinetic approach to assess oxidative metabolism related features in the bivalve Mya arenaria
    Paula Mariela González
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
    Theory Biosci 131:253-64. 2012
    ..This data can be further used as a basis to assess the cellular response to stress in a simple system as the bivalve M. arenaria that can then be compared to cells of higher organisms...
  23. ncbi Mitochondrial ferritin in animals and plants
    Andrea Galatro
    Physical Chemistry PRALIB, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
    Front Biosci 12:1063-71. 2007
    ....
  24. ncbi The effect of seasonality on oxidative metabolism in Nacella (Patinigera) magellanica
    Gabriela Malanga
    Centro Austral de Investigaciones Científicas CADIC CONICET c c 92 9410 Ushuaia, Tierra del Fuego, Argentina
    Comp Biochem Physiol A Mol Integr Physiol 146:551-8. 2007
    ..Together, the data indicate that both oxygen and nitrogen radical generation rates in N. (P.) magellanica are strongly dependent on season...
  25. ncbi Oxidative stress and HIF-1 DNA binding during stressful cold exposure and recovery in the North Sea eelpout (Zoarces viviparus)
    Katja Heise
    Alfred-Wegener-Institute for Polar and Marine Research, Physiology of Marine Animals, Am Handelshafen 12, 27570 Bremerhaven, Germany
    Comp Biochem Physiol A Mol Integr Physiol 143:494-503. 2006
    ..Notably the non-enzymatic antioxidant defense (e.g. glutathione) may play an important role for eelpout ROS scavenging capacity under cold stress...
  26. ncbi Oxidative stress in limpets exposed to different environmental conditions in the Beagle Channel
    Gabriela Malanga
    , C.C. 92 9410 Ushuaia, Tierra del Fuego, Argentina
    Aquat Toxicol 69:299-309. 2004
    ..It is likely that N. (P.) magellanica has a particular evolutionary adaptation to extreme environmental conditions by keeping iron content low and antioxidant activities high...
  27. ncbi The role of nitric oxide in the radiation-induced effects in the developing brain
    Pablo Gisone
    Nuclear Regulatory Authority, Scientific Support, Radiopathology Laboratory, Libertador 8250 C1429BNP Buenos Aires, Argentina
    In Vivo 18:281-92. 2004
    ....
  28. ncbi Formation of reactive species and induction of antioxidant defence systems in polar and temperate marine invertebrates and fish
    Doris Abele
    Alfred Wegener Institut for Polar and Marine Research, Marine Ecophysiology Ecotoxicology, Columbusstr 27568 Bremerhaven, Germany
    Comp Biochem Physiol A Mol Integr Physiol 138:405-15. 2004
    ....
  29. ncbi Oxidative stress during stressful heat exposure and recovery in the North Sea eelpout Zoarces viviparus L
    Katja Heise
    Alfred-Wegener Institute for Polar and Marine Research, Physiology of Marine Animals, Am Handelshafen 12, 27570 Bremerhaven, Germany
    J Exp Biol 209:353-63. 2006
    ..We suppose that the more oxidized redox state during extreme heat may interfere with the hypoxic signaling response...
  30. ncbi Reactive species and apoptosis of neural precursor cells after gamma-irradiation
    Pablo Gisone
    Nuclear Regulatory Authority, Radiopathology Laboratory, Avenida del Libertador 8250 (C1429BNP) Buenos Aires, Argentina
    Neurotoxicology 27:253-9. 2006
    ..However, despite this NO initial protective effect and its role modulating the response against gamma-radiation, NO generation was not able of fully preventing radiation-induced apoptosis...
  31. ncbi Marine invertebrate mitochondria and oxidative stress
    Eoris Abele
    Alfred Wegener Institute for Polar and Marine Research, Dept Marine Animal Physiology and Function, D 27570 Bremerhaven, Germany
    Front Biosci 12:933-46. 2007
    ..A new concept is proposed, showing how the cross talk of reactive O2 species in metabolically low marine invertebrates could support their outstanding hypoxia tolerance under non-stressed conditions...