Alberto R Kornblihtt
Affiliation: Universidad de Buenos Aires
Godoy Herz M, Kubaczka M, Brzyżek G, Servi L, Krzyszton M, Simpson C, et al
. Light Regulates Plant Alternative Splicing through the Control of Transcriptional Elongation. Mol Cell. 2019;: pubmed publisher
Kornblihtt A. CTCF: from insulators to alternative splicing regulation. Cell Res. 2012;22:450-2 pubmed publisher
Buggiano V, Petrillo E, AllÃ³ M, Lafaille C, Redal M, Alghamdi M, et al
. Effects of airborne particulate matter on alternative pre-mRNA splicing in colon cancer cells. Environ Res. 2015;140:185-90 pubmed publisher
..We also show that the underlying mechanism might involve changes in transcriptional elongation. This is the first study to demonstrate that particulate matter causes non-pleiotropic changes in alternative splicing. ..
Nieto Moreno N, Giono L, Cambindo Botto A, MuÃ±oz M, Kornblihtt A. Chromatin, DNA structure and alternative splicing. FEBS Lett. 2015;589:3370-8 pubmed publisher
..Herein we discuss the evidence supporting the influence of template structural modifications on transcription and splicing, and provide insights about possible roles of non-B DNA conformations on the regulation of alternative splicing. ..
Agirre E, Bellora N, AllÃ³ M, PagÃ¨s A, Bertucci P, Kornblihtt A, et al
. A chromatin code for alternative splicing involving a putative association between CTCF and HP1Î± proteins. BMC Biol. 2015;13:31 pubmed publisher
..Additionally, we find further evidence for the involvement of HP1Î± and AGO1 in chromatin-related splicing regulation. ..
Giono L, Nieto Moreno N, Cambindo Botto A, Dujardin G, MuÃ±oz M, Kornblihtt A. The RNA Response to DNA Damage. J Mol Biol. 2016;428:2636-2651 pubmed publisher
..This review aims to present a comprehensive overview of the current knowledge on the many interactions between the DNA damage and RNA fields. ..
Fiszbein A, Giono L, Quaglino A, Berardino B, Sigaut L, von Bilderling C, et al
. Alternative Splicing of G9a Regulates Neuronal Differentiation. Cell Rep. 2016;14:2797-808 pubmed publisher
..Overall, our findings indicate that by regulating its own alternative splicing, G9a promotes neuron differentiation and creates a positive feedback loop that reinforces cellular commitment to differentiation. ..
Kornblihtt A, Schor I, Allo M, Dujardin G, Petrillo E, Munoz M. Alternative splicing: a pivotal step between eukaryotic transcription and translation. Nat Rev Mol Cell Biol. 2013;14:153-65 pubmed publisher
Dujardin G, Lafaille C, De la Mata M, Marasco L, Munoz M, Le Jossic Corcos C, et al
. How slow RNA polymerase II elongation favors alternative exon skipping. Mol Cell. 2014;54:683-90 pubmed publisher
..This indicates that a delay in the cotranscriptional emergence of the 5' ss promotes ETR-3 recruitment and subsequent inhibition of E9 inclusion. ..