Research Topics
| S L ArnaizSummaryAffiliation: Universidad de Buenos Aires Country: Argentina Publications
| Collaborators
|
Detail Information
Publications
Nitric oxide, superoxide, and hydrogen peroxide production in brain mitochondria after haloperidol treatmentS L Arnaiz
School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina
Nitric Oxide 3:235-43. 1999..This inhibition does not seem to be caused by increased NO or ONOO- formation...
Age-related alterations in mitochondrial physiological parameters and nitric oxide production in synaptic and non-synaptic brain cortex mitochondriaS Lores-Arnaiz
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, C1113AAD Buenos Aires, Argentina
Neuroscience 188:117-24. 2011..Non-synaptic mitochondria would be more resistant to age-related dysfunction and oxidative damage...
Mitochondrial function and nitric oxide production in hippocampus and cerebral cortex of rats exposed to enriched environmentS Lores-Arnaiz
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina
Brain Res 1319:44-53. 2010..Our results suggest that in hippocampus and cerebral cortex, EE exposure protects mitochondria against calcium-induced MPT maintaining a convenient membrane potential, which assures a continuous energy supply...
Exposure to enriched environments increases brain nitric oxide synthase and improves cognitive performance in prepubertal but not in young ratsS Lores-Arnaiz
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina
Behav Brain Res 184:117-23. 2007..These results support the hypothesis that brief exposure to EE and training produce effects on behavioral performance and on biochemical parameters in an age-dependent manner...
Hippocampal mitochondrial dysfunction with decreased mtNOS activity in prehepatic portal hypertensive ratsSilvia Lores-Arnaiz
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina
Neurochem Int 47:362-8. 2005..It is concluded that the moderate increase in plasma ammonia that followed portal hypertension was the potential primary cause of the observed alterations...
Brain mitochondrial nitric oxide synthase: in vitro and in vivo inhibition by chlorpromazineSilvia Lores-Arnaiz
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina
Arch Biochem Biophys 430:170-7. 2004..Results indicate that chlorpromazine inhibits brain mtNOS activity in vitro and can exert the same action in vivo...
Dopamine enhances mtNOS activity: implications in mitochondrial functionAnalia Czerniczyniec
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, C1113AAD, Buenos Aires, Argentina
Biochim Biophys Acta 1767:1118-25. 2007..This work provides evidence that in the studied conditions, dopamine modifies mitochondrial function by a nitric oxide-dependent pathway...
Extensive enriched environments protect old rats from the aging dependent impairment of spatial cognition, synaptic plasticity and nitric oxide productionS Lores-Arnaiz
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, C1113AAD Buenos Aires, Argentina
Behav Brain Res 169:294-302. 2006..Complex I activity was 70-80% increased in EE as compared to SE rats. A significant increase in the area of NADPH-d reactive neurons was observed in the parietotemporal cortex and CA1 hippocampal region of EE animals...
Mitochondrial dysfunction as a mediator of hippocampal apoptosis in a model of hepatic encephalopathyJ Bustamante
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, C1113AAD Buenos Aires, Argentina
Mol Cell Biochem 354:231-40. 2011..In addition, in vitro studies performed in mitochondria from sham animals showed that mitochondrial permeability transition (MPT) could be a mitochondrial mediator of the apoptotic signaling in the presence of NH(4) (+) and calcium...
Paraquat induces behavioral changes and cortical and striatal mitochondrial dysfunctionA Czerniczyniec
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
Free Radic Biol Med 51:1428-36. 2011..We demonstrate that paraquat induced alterations in nonmotor symptoms and cortical and striatal mitochondrial dysfunction...
Long-term angiotensin II inhibition increases mitochondrial nitric oxide synthase and not antioxidant enzyme activities in rat heartLidia E Costa
Instituto de Investigaciones Cardiologicas, Facultad de Medicina, Universidad de Buenos Aires, Argentina
J Hypertens 20:2487-94. 2002..To provide insight into the subcellular mechanisms involved in the improvement of cardiovascular structure and function by long-term inhibition of the renin-angiotensin system...
Age related changes from youth to adulthood in rat brain cortex: nitric oxide synthase and mitochondrial respiratory functionJuanita Bustamante
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, Buenos Aires C1113AAD, Argentina
Neurochem Res 33:1216-23. 2008..During rat growth, the respiratory function seems to be modulated by NO produced by the different NOS enzymes: nNOS, eNOS and mtNOS present in the cytosol and in the mitochondria...
Brain nitric oxide synthases and mitochondrial functionJuanita Bustamante
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
Front Biosci 12:1034-40. 2007..All these results seems to be clearly related with the reversible and concentration-dependent attenuation of the respiratory chain by NO...
Reactions of peroxynitrite in the mitochondrial matrixL B Valdez
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University Hospital, School of Medicine, University of Buenos Aires, Argentina
Free Radic Biol Med 29:349-56. 2000..An intramitochondrial steady state concentration of about 2 nM ONOO- was calculated, taking into account the rate constants and concentrations of ONOO- coreactants...
Improvement of mouse brain mitochondrial function after deprenyl treatmentA Czerniczyniec
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, C1113AAD, Buenos Aires, Argentina
Neuroscience 144:685-93. 2007....
Dopamine modifies oxygen consumption and mitochondrial membrane potential in striatal mitochondriaAnalia Czerniczyniec
Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956, C1113AAD Buenos Aires, Argentina
Mol Cell Biochem 341:251-7. 2010....
