Research Topics
Genomes and GenesSpecies | R R ForastieroSummaryAffiliation: Favaloro University Country: Argentina Publications
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Detail Information
Publications
A prospective study of antibodies to beta2-glycoprotein I and prothrombin, and risk of thrombosisR Forastiero
Division of Hematology, Thrombosis and Hemostasis, Institute of Cardiology and Cardiovascular Surgery, Favaloro Foundation, Favaloro University, Buenos Aires, Argentina
J Thromb Haemost 3:1231-8. 2005..4% per patient-year). In conclusion, the presence of IgG anti-beta2GPI and anti-PT in patients with LA and/or aCL and mainly in those with LA predicts a higher risk of thromboembolic events...
Circulating levels of tissue factor and proinflammatory cytokines in patients with primary antiphospholipid syndrome or leprosy related antiphospholipid antibodiesR R Forastiero
Favaloro University, Favaloro Foundation, Buenos Aires, Argentina
Lupus 14:129-36. 2005..The different cytokine profiles as well as differences in circulating levels of TF might contribute to the high thrombotic risk found in patients with autoimmune aPL but not in leprosy related aPL patients...
Autoimmune antiphospholipid antibodies impair the inhibition of activated factor X by protein Z/protein Z-dependent protease inhibitorR R Forastiero
Division of Haematology, Thrombosis and Haemostasis, Favaloro University, Favaloro Foundation, Buenos Aires, Argentina
J Thromb Haemost 1:1764-70. 2003..Taken together, these data suggest that the PZ/ZPI system is commonly impaired in aPL patients thus probably increasing the thrombotic risk...
High titers of autoantibodies to tissue factor pathway inhibitor are associated with the antiphospholipid syndromeR R Forastiero
Division of Haematology, Thrombosis and Haemostasis, Favaloro University, Favaloro Foundation, Buenos Aires, Argentina
J Thromb Haemost 1:718-24. 2003..Thus, aPL with high titer anti-TFPI limit TFPI action and are associated with the APS...
High prevalence of antiphospholipid antibodies in leprosy: evaluation of antigen reactivityG F de Larrañaga
Section of Biochemistry, Thrombosis and Haemostasis, Hospital of Infectious Diseases FJ Muñiz, Buenos Aires, Argentina
Lupus 9:594-600. 2000..In summary, leprosy-related aPL resemble those found in patients with APS but the immunoglobulin isotype is different, with IgM much more prevalent in leprosy patients...
Increased lipid peroxidation correlates with platelet activation but not with markers of endothelial cell and blood coagulation activation in patients with antiphospholipid antibodiesM E Martinuzzo
Institute of Cardiology and Cardiovascular Surgery, Division of Haematology, the Favaloro University School of Medicine, Favaloro Foundation, , Buenos Aires, Argentina
Br J Haematol 114:845-51. 2001..Platelet activation, lipid peroxidation and blood coagulation activation seem to be important in the pathophysiology of antiphospholipid syndrome...
Markers of platelet, endothelial cell and blood coagulation activation in leprosy patients with antiphospholipid antibodiesM E Martinuzzo
Division of Haematology, Favaloro University, Favaloro Foundation, Buenos Aires, Argentina
Clin Exp Rheumatol 20:477-83. 2002..CONCLUSIONS: We demonstrated that although patients with leprosy present a high prevalence of aPL, and platelet and endothelial cell activation in vivo to the same extent than patients with APS, they do not show a procoagulant state...
Central retinal vein occlusion and thrombophilia risk factorsY P Adamczuk
Department of Haematology, Thrombosis and Haemostasis, Favaloro University, Buenos Aires, Argentina
Blood Coagul Fibrinolysis 13:623-6. 2002..5%, P < 0.001 and 2.1%, P < 0.01, respectively). Both hyperhomocysteinaemia and antiphospholipid antibodies seem to be associated with CRVO. A search for acquired thrombophilia is advisable in patients with CRVO...
Different types of antiphospholipid antibodies in AIDS: a comparison with syphilis and the antiphospholipid syndromeG F de Larrañaga
Hospital of Infectious Diseases F J Muñiz, Buenos Aires, Argentina
Thromb Res 96:19-25. 1999..Autoimmune antiphospholipid antibodies in HIV without clinical features of antiphospholipid syndrome might be a reflex of the immunological chaos and/or the constant antigenic virus stimulus...
Link between anti-CD36 antibodies and thrombosis in the antiphospholipid syndromeY Pelegri
Division of Haematology, Favaloro University, Favaloro Foundation, Buenos Aires, Argentina
Clin Exp Rheumatol 21:221-4. 2003..8% vs 15.8%). CONCLUSION: The presence of anti-CD36 is highly prevalent in patients with autoimmune aPL with a trend to being more frequent in patients with recurrent episodes of thrombosis...
Thrombophilic factors in chronic thromboembolic pulmonary hypertensionC C Colorio
Department of Hematology, Institute of Cardiology and Cardiovascular Surgery, Favaloro University, Favaloro Foundation, Buenos Aires, Argentina
Blood Coagul Fibrinolysis 12:427-32. 2001..We recommend a thorough screening for thrombophilia in all patients with diagnosis of CTE-PH...
New guidelines for lupus anticoagulant: sensitivity and specificity of cut-off values calculated with plasmas from healthy controls in mixing and confirmatory testsM E Martinuzzo
Division of Hematology, Thrombosis, and Haemostasis, University Hospital, Favaloro Foundation, Buenos Aires, Argentina
Int J Lab Hematol 34:208-13. 2012..Conclusion: The combination of mixing and confirmatory tests interpreted according to the new guidelines can clearly differentiate LA from other coagulopathies...
Which are the best biological markers of the antiphospholipid syndrome?L O Carreras
Department of Haematology, Thrombosis and Haemostasis, Favaloro University, Favaloro Foundation, Buenos Aires, Argentina
J Autoimmun 15:163-72. 2000....
Major and potential prothrombotic genotypes in a cohort of patients with venous thromboembolismM L Varela
Department of Haematology, Thrombosis and Haemostasis, Favaloro University, Buenos Aires, Argentina
Thromb Res 104:317-24. 2001..92, P<.0001). We conclude that FVL and the PT-20210A are risk factors for VT as well as Hcy levels, but the MTHFR and PAI-1 polymorphisms do not appear to be associated with VT in our country...
Catastrophic antiphospholipid syndrome and Kikuchi-Fujimoto disease: the first case reportedG F de Larrañaga
Hemostasis and Thrombosis Laboratory, Muñiz Hospital, Buenos Aires, Argentina
Lupus 14:967-9. 2005..Cytomegalovirus could be involved in the development of both CAPS and KFD. Because of the severity of the case, we believe that XIGRIS noticeable improved the altered coagulation profile associated with CAPS...
Antibodies to tissue factor pathway inhibitor are uncommonly detected in patients with infection-related antiphospholipid antibodiesR R Forastiero
J Thromb Haemost 1:2250-1. 2003
