Josephine Arendt

Summary

Publications

  1. ncbi request reprint Human circadian phase in 12:12 h, 200: <8 lux and 1000: <8 lux light-dark cycles, without scheduled sleep or activity
    Benita Middleton
    Centre for Chronobiology, School of Biomedical and Life Sciences, University of Surrey, Guildford, Surrey GU2 5XH, UK
    Neurosci Lett 329:41-4. 2002
  2. doi request reprint Shift work: coping with the biological clock
    Josephine Arendt
    Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK
    Occup Med (Lond) 60:10-20. 2010
  3. ncbi request reprint Sleep and circadian phase in a ship's crew
    Josephine Arendt
    Centre for Chronobiology, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, United Kingdom
    J Biol Rhythms 21:214-21. 2006
  4. ncbi request reprint Melatonin: characteristics, concerns, and prospects
    Josephine Arendt
    Centre for Chronobiology, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, Surrey, United Kingdom
    J Biol Rhythms 20:291-303. 2005
  5. doi request reprint Managing jet lag: Some of the problems and possible new solutions
    Josephine Arendt
    Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK
    Sleep Med Rev 13:249-56. 2009
  6. doi request reprint Alertness, mood and performance rhythm disturbances associated with circadian sleep disorders in the blind
    Steven W Lockley
    School of Biomedical and Molecular Sciences, University of Surrey, Guildford, UK
    J Sleep Res 17:207-16. 2008
  7. ncbi request reprint A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference
    Simon N Archer
    Centre for Chronobiology, School of Biomedical and Life Science, University of Surrey, Guildford GU2 7XH, UK
    Sleep 26:413-5. 2003
  8. ncbi request reprint Robust circadian rhythm in heart rate and its variability: influence of exogenous melatonin and photoperiod
    Gilles Vandewalle
    Surrey Sleep Research Centre, University of Surrey, Guildford, UK
    J Sleep Res 16:148-55. 2007
  9. doi request reprint Differences in sleep, light, and circadian phase in offshore 18:00-06:00 h and 19:00-07:00 h shift workers
    Helen Thorne
    Faculty of Health and Medical Sciences, Neuroendocrinology Group, Centre for Chronobiology, University of Surrey, Guildford, Surrey, UK
    Chronobiol Int 25:225-35. 2008
  10. pmc Melatonin advances the circadian timing of EEG sleep and directly facilitates sleep without altering its duration in extended sleep opportunities in humans
    Shantha M W Rajaratnam
    School of Biomedical and Molecular Sciences, University of Surrey, UK
    J Physiol 561:339-51. 2004

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Human circadian phase in 12:12 h, 200: <8 lux and 1000: <8 lux light-dark cycles, without scheduled sleep or activity
    Benita Middleton
    Centre for Chronobiology, School of Biomedical and Life Sciences, University of Surrey, Guildford, Surrey GU2 5XH, UK
    Neurosci Lett 329:41-4. 2002
    ..81 h in temperature. These observations suggest that domestic intensity light does not maintain phase without scheduled sleep/activity, possibly due to indirect effects on behaviour influencing light exposure...
  2. doi request reprint Shift work: coping with the biological clock
    Josephine Arendt
    Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK
    Occup Med (Lond) 60:10-20. 2010
    ..The most important factor in manipulating the circadian system is exposure to and/or avoidance of bright light at specific times of the 'biological night'...
  3. ncbi request reprint Sleep and circadian phase in a ship's crew
    Josephine Arendt
    Centre for Chronobiology, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, United Kingdom
    J Biol Rhythms 21:214-21. 2006
    ..01). This study identifies weekly changes in watch time as a cause of poor sleep in watch keepers. The most likely mechanism is the inability of the internal clock to adapt rapidly to abrupt changes in schedule...
  4. ncbi request reprint Melatonin: characteristics, concerns, and prospects
    Josephine Arendt
    Centre for Chronobiology, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, Surrey, United Kingdom
    J Biol Rhythms 20:291-303. 2005
    ..The future holds much promise for melatonin as a therapeutic treatment. Most interesting, however, will be the dissection of its effects on human genes...
  5. doi request reprint Managing jet lag: Some of the problems and possible new solutions
    Josephine Arendt
    Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK
    Sleep Med Rev 13:249-56. 2009
    ..The maximum efficacy for jet lag avoidance is by pre-flight adaptation, however, this requires time and commitment...
  6. doi request reprint Alertness, mood and performance rhythm disturbances associated with circadian sleep disorders in the blind
    Steven W Lockley
    School of Biomedical and Molecular Sciences, University of Surrey, Guildford, UK
    J Sleep Res 17:207-16. 2008
    ..Treatment for circadian rhythm disorders should be targeted in normalizing these phase relationships...
  7. ncbi request reprint A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference
    Simon N Archer
    Centre for Chronobiology, School of Biomedical and Life Science, University of Surrey, Guildford GU2 7XH, UK
    Sleep 26:413-5. 2003
    ..To investigate the link between extreme diurnal preference, delayed sleep phase syndrome, and a length polymorphism in Per3...
  8. ncbi request reprint Robust circadian rhythm in heart rate and its variability: influence of exogenous melatonin and photoperiod
    Gilles Vandewalle
    Surrey Sleep Research Centre, University of Surrey, Guildford, UK
    J Sleep Res 16:148-55. 2007
    ....
  9. doi request reprint Differences in sleep, light, and circadian phase in offshore 18:00-06:00 h and 19:00-07:00 h shift workers
    Helen Thorne
    Faculty of Health and Medical Sciences, Neuroendocrinology Group, Centre for Chronobiology, University of Surrey, Guildford, Surrey, UK
    Chronobiol Int 25:225-35. 2008
    ..In these offshore conditions in summer, the earlier shift start and end time appears to favor daytime sleep...
  10. pmc Melatonin advances the circadian timing of EEG sleep and directly facilitates sleep without altering its duration in extended sleep opportunities in humans
    Shantha M W Rajaratnam
    School of Biomedical and Molecular Sciences, University of Surrey, UK
    J Physiol 561:339-51. 2004
    ....
  11. pmc Biological rhythms during residence in polar regions
    Josephine Arendt
    Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK
    Chronobiol Int 29:379-94. 2012
    ..They apply equally to people living in temperate zones with insufficient light exposure...
  12. ncbi request reprint Phase advancing human circadian rhythms with short wavelength light
    Victoria L Warman
    Centre for Chronobiology, School of Biomedical and Life Sciences, University of Surrey, Surrey, GU2 7XH, Guildford, UK
    Neurosci Lett 342:37-40. 2003
    ..This finding suggests short wavelength sensitivity of the photoreceptors mediating synchronization of human circadian rhythms...
  13. ncbi request reprint The effects of low-dose 0.5-mg melatonin on the free-running circadian rhythms of blind subjects
    Lisa M Hack
    Centre for Chronobiology, School of Biomedical and Life Sciences, University of Surrey, Guildford, GU2 7XH, UK
    J Biol Rhythms 18:420-9. 2003
    ..Optimal treatment with melatonin for this non-24-h sleep disorder should correct the underlying circadian disorder (to entrain the sleep-wake cycle) in addition to improving sleep acutely...
  14. ncbi request reprint Melatonin and human rhythms
    Josephine Arendt
    Centre for Chronobiology, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, England
    Chronobiol Int 23:21-37. 2006
    ..Endogenous melatonin acts to reinforce the functioning of the human circadian system, probably in many ways. The future holds much promise for melatonin as a research tool and as a therapy for various conditions...
  15. ncbi request reprint Circadian rhythm sleep disorders in the blind and their treatment with melatonin
    Debra J Skene
    Centre for Chronobiology, School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UK
    Sleep Med 8:651-5. 2007
    ..If practicable, assessment of an individual's circadian phase (by measurement of the endogenous melatonin rhythm in plasma, saliva or urine) is recommended prior to commencing treatment to optimise melatonin's effectiveness...
  16. ncbi request reprint Melatonin phase-shifts human circadian rhythms with no evidence of changes in the duration of endogenous melatonin secretion or the 24-hour production of reproductive hormones
    Shantha M W Rajaratnam
    Centre for Chronobiology, School of Biomedical and Life Sciences, University of Surrey, Guildford GU2 7XH, United Kingdom
    J Clin Endocrinol Metab 88:4303-9. 2003
    ....
  17. ncbi request reprint Human circadian rhythms: physiological and therapeutic relevance of light and melatonin
    Debra J Skene
    Centre for Chronobiology, School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UK
    Ann Clin Biochem 43:344-53. 2006
    ....
  18. ncbi request reprint Melatonin as a chronobiotic
    Josephine Arendt
    School of Biomedical and Molecular Sciences, Centre for Chronobiology, University of Surrey, Guildford, Surrey GU2 7XH, UK
    Sleep Med Rev 9:25-39. 2005
    ..No long-term safety data exist, and the optimum dose and formulation for any application remains to be clarified...
  19. ncbi request reprint Alerting effects of light are sensitive to very short wavelengths
    Victoria L Revell
    School of Biomedical and Molecular Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, UK
    Neurosci Lett 399:96-100. 2006
    ..05). These data (420 nm>470 nm>600 nm) suggest that subjective alertness may be maximally sensitive to very short wavelength light...
  20. ncbi request reprint The 3111 Clock gene polymorphism is not associated with sleep and circadian rhythmicity in phenotypically characterized human subjects
    Donna L Robilliard
    Centre for Chronobiology, School of Biomedical and Life Sciences, University of Surrey, Guildford, UK
    J Sleep Res 11:305-12. 2002
    ..No significant difference was observed between the two variants. These results do not support Clock 3111C as a marker for diurnal preference, tau, or delayed sleep phase syndrome in humans...
  21. ncbi request reprint Circadian aspects of postprandial metabolism
    Linda Morgan
    School of Biomedical and Life Sciences, University of Surrey, Guildford, UK
    Chronobiol Int 20:795-808. 2003
    ..As both insulin resistance and elevated circulating TAG are independent risk factors for heart disease, it is possible that meals at night may contribute to this risk...
  22. ncbi request reprint Clinical update: melatonin and sleep disorders
    Josephine Arendt
    Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford
    Clin Med 8:381-3. 2008
    ..Anecdotal evidence for the use of melatonin needs to be replaced by data from well-controlled, preferably multi-centre, randomised clinical trials...
  23. pmc Does melatonin improve sleep? Efficacy of melatonin
    Josephine Arendt
    BMJ 332:550. 2006
  24. ncbi request reprint Predicting circadian response to abrupt phase shift: 6-sulphatoxymelatonin rhythms in rotating shift workers offshore
    Michelle Gibbs
    J Biol Rhythms 22:368-70. 2007
  25. ncbi request reprint Does melatonin improve sleep in older people? A randomised crossover trial
    Jonathan J Baskett
    Home and Older Adults Services, Waitemata Health Ltd, Private Bag 93 503, Takapuna, Auckland, New Zealand
    Age Ageing 32:164-70. 2003
    ..to determine whether melatonin will improve quality of sleep in healthy older people with age-related sleep maintenance problems...
  26. pmc Visual impairment and circadian rhythm disorders
    Steven W Lockley
    Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
    Dialogues Clin Neurosci 9:301-14. 2007
    ..Daily melatonin administration, which provides a replacement synchronizing daily "time cue, " is a promising therapeutic strategy, although optimal treatment dose and timing remain to be determined...
  27. ncbi request reprint Circadian phase delay induced by phototherapeutic devices
    Michel A Paul
    DRDC Toronto, Toronto, Ontario, Canada
    Aviat Space Environ Med 78:645-52. 2007
    ..The work reported here compared four phototherapeutic devices for efficacy in effecting circadian phase delays...
  28. ncbi request reprint Aaron Lerner, who discovered melatonin
    Josephine Arendt
    J Pineal Res 43:106-7. 2007
  29. ncbi request reprint A tribute to Aaron Lerner
    Josephine Arendt
    Chronobiol Int 24:383-5. 2007
  30. ncbi request reprint Short-wavelength sensitivity of the human circadian system to phase-advancing light
    Victoria L Revell
    J Biol Rhythms 20:270-2. 2005