Salah E Aref

Summary

Publications

  1. ncbi request reprint Cyclin D1 expression in acute leukemia
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura, Egypt
    Hematology 11:31-4. 2006
  2. ncbi request reprint Angiogenesis factor pattern differs in acute lymphoblastic leukemia and chronic lymphocytic leukemia
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura, Egypt
    Hematology 12:319-24. 2007
  3. doi request reprint Antiplatelet antibodies contribute to thrombocytopenia associated with chronic hepatitis C virus infection
    Salah Aref
    Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura University, Egypt
    Hematology 14:277-81. 2009
  4. doi request reprint Clinicopathologic Effect of DNMT3A Mutation in Adult T-Cell Acute Lymphoblastic Leukemia
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura University Faculty of Medicine, Mansoura, Egypt Electronic address
    Clin Lymphoma Myeloma Leuk 16:43-8. 2016
  5. doi request reprint Prevalence and Clinical Effect of IDH1 and IDH2 Mutations Among Cytogenetically Normal Acute Myeloid Leukemia Patients
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura University, Mansoura, Egypt Electronic address
    Clin Lymphoma Myeloma Leuk 15:550-5. 2015
  6. doi request reprint Telomerase reverse transcriptase (TERT) A1062T mutation as a prognostic factor in Egyptian patients with acute myeloid leukemia (AML)
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura, Egypt
    Med Oncol 31:158. 2014
  7. doi request reprint Prevalence and impact of colony stimulating factor 3 receptor (CSF3R) mutations among Egyptian acute myeloid leukemia patients
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura University Oncology Center, Mansoura Faculty of Medicine, Mansoura, Egypt Electronic address
    Leuk Res 38:722-5. 2014
  8. doi request reprint Increased VWF antigen levels and decreased ADAMTS13 activity in preeclampsia
    Salah Aref
    Clinical Pathology Department, Hematology Unit, Mansoura Faculty of Medicine, Mansoura, Egypt
    Hematology 18:237-41. 2013
  9. doi request reprint Impact of serum adiponectin and leptin levels in acute leukemia
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura, Egypt
    Hematology 18:198-203. 2013
  10. doi request reprint Prognostic impact of serum 25-hydroxivitamin D [25(OH)D] concentrations in patients with lymphoid malignancies
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura University, Mansoura 3011, Egypt
    Hematology 18:20-5. 2013

Detail Information

Publications26

  1. ncbi request reprint Cyclin D1 expression in acute leukemia
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura, Egypt
    Hematology 11:31-4. 2006
    ..Over expression of cyclin D1 protein has been reported in several solid tumors and certain lymphoid malignancies, but little is known about the involvement of cyclin D1 in acute leukemia...
  2. ncbi request reprint Angiogenesis factor pattern differs in acute lymphoblastic leukemia and chronic lymphocytic leukemia
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura, Egypt
    Hematology 12:319-24. 2007
    ..In conclusion, our data suggest that the driving forces of angiogenic factors (VEGF, TNF-alpha and MMP-9) in adult B-ALL appears different from that in B-CLL patients...
  3. doi request reprint Antiplatelet antibodies contribute to thrombocytopenia associated with chronic hepatitis C virus infection
    Salah Aref
    Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura University, Egypt
    Hematology 14:277-81. 2009
    ..42, p=0.024), and significantly parallel to spleen size (p=0.024). Platelet associated glycoprotein specific antibodies represent a common mechanism inducing thrombocytopenia in patients with chronic HCV infections...
  4. doi request reprint Clinicopathologic Effect of DNMT3A Mutation in Adult T-Cell Acute Lymphoblastic Leukemia
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura University Faculty of Medicine, Mansoura, Egypt Electronic address
    Clin Lymphoma Myeloma Leuk 16:43-8. 2016
    ..The present study aimed to determine the frequencies and clinicopathologic effect of a DNMT3A [DNA (cytosine-5)-methyltransferase 3A] mutation in patients with adult T-cell acute lymphoblastic leukemia (T-ALL)...
  5. doi request reprint Prevalence and Clinical Effect of IDH1 and IDH2 Mutations Among Cytogenetically Normal Acute Myeloid Leukemia Patients
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura University, Mansoura, Egypt Electronic address
    Clin Lymphoma Myeloma Leuk 15:550-5. 2015
    ..The aim of this study was to determine the frequencies of IDH1 and IDH2 mutations among Egyptian AML patients and its effect on patient outcomes...
  6. doi request reprint Telomerase reverse transcriptase (TERT) A1062T mutation as a prognostic factor in Egyptian patients with acute myeloid leukemia (AML)
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura, Egypt
    Med Oncol 31:158. 2014
    ..In conclusion, TERT A1062T mutation is an independent negative prognostic factor in AML patients. Therefore, molecular testing for TERT A1062T mutation in patients with AML is recommended in order to delineate their prognostic status...
  7. doi request reprint Prevalence and impact of colony stimulating factor 3 receptor (CSF3R) mutations among Egyptian acute myeloid leukemia patients
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura University Oncology Center, Mansoura Faculty of Medicine, Mansoura, Egypt Electronic address
    Leuk Res 38:722-5. 2014
    ..In conclusion the frequency of CSF3R mutations is highly prevalent among AML patients secondary to SCN compared to de novo AML. ..
  8. doi request reprint Increased VWF antigen levels and decreased ADAMTS13 activity in preeclampsia
    Salah Aref
    Clinical Pathology Department, Hematology Unit, Mansoura Faculty of Medicine, Mansoura, Egypt
    Hematology 18:237-41. 2013
    ..01 for both). In conclusion, reduction of plasma ADAMTS13 and elevation in VWF might have a role in the pathogenesis of PE. ..
  9. doi request reprint Impact of serum adiponectin and leptin levels in acute leukemia
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura, Egypt
    Hematology 18:198-203. 2013
    ..Estimation of adiponectin and leptin serum levels at acute leukemia diagnosis could also be considered as a prognostic marker, which will be used in acute leukemia stratification. ..
  10. doi request reprint Prognostic impact of serum 25-hydroxivitamin D [25(OH)D] concentrations in patients with lymphoid malignancies
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura University, Mansoura 3011, Egypt
    Hematology 18:20-5. 2013
    ..In conclusion, 25(OH)D insufficiency is an independent poor prognostic factor in patients with B-CLL and NHL. 25(OH)D might be a therapeutic target in lymphoid malignancies...
  11. doi request reprint Effect of splenectomy on platelets associated antibodies in hepatitis C patients with thrombocytopenia
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Faculty of Medicine, Mansoura University, Egypt
    Hematology 17:118-21. 2012
    ..This study aimed to assess the role of splenomegaly as a source of platelet-associated immunoglobulins (PAIgs) in thrombocytopenic patients with chronic hepatitis C virus (HCV) infection...
  12. ncbi request reprint Urokinase plasminogen activator receptor and soluble matrix metalloproteinase-9 in acute myeloid leukemia patients: a possible relation to disease invasion
    S Aref
    Hematology Unit, Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura, Egypt
    Hematology 8:385-91. 2003
    ..001 for all). In conclusion, MMP-9 and su PAR levels might be used as a marker for disease activity and may contribute to blast cell dissemination. MMP-9 and suPAR may be target molecules in the strategy of treatment of AML...
  13. doi request reprint Elevated serum endostatin levels are associated with favorable outcome in acute myeloid leukemia
    S Aref
    Mansoura Cancer Institute Mansoura Faculty of Medicine, Mansoura University, Egypt
    Hematology 13:95-100. 2008
    ..The levels and the prognostic relevance of serum endostatin in acute myeloid leukaemia (AML) patient are not fully clear...
  14. ncbi request reprint Prognostic relevance of circulating matrix metalloproteinase-2 in acute myeloid leukaemia patients
    Salah Aref
    Mansoura Cancer Institute Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt
    Hematol Oncol 25:121-6. 2007
    ..High pretreatment levels of sMMP-2 among AML patients were associated with poor survival. Prospective studies are recommended to establish the clinical value of longitudinal sMMP-2 measurement...
  15. ncbi request reprint Syndecan-1 in multiple myeloma: relationship to conventional prognostic factors
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt
    Hematology 8:221-8. 2003
    ..Assessment of soluble syndecan-1 and beta2 microglobulin at diagnosis is an independent prognostic system for MM...
  16. ncbi request reprint Soluble P-selectin levels in diabetes mellitus patients with coronary artery disease
    Salah Aref
    Mansoura Faculty of Medicine, Hematology Unit, Clinical Pathology Department, Mansoura, Egypt
    Hematology 10:183-7. 2005
    ....
  17. ncbi request reprint Soluble VEGF/sFLt1 ratio is an independent predictor of AML patient out come
    Salah Aref
    Hematology Unit, Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura, Egypt
    Hematology 10:131-4. 2005
    ..In conclusion, sVEGF/sVEGF ratio is independent predictor of AML patient out come, and its significance should be assessed when considering antiangiogenic therapy...
  18. ncbi request reprint Thrombopoietin (TPO) levels in hepatic patients with thrombocytopenia
    Salah Aref
    Department of Clinical Pathology, Hematology Unit, Mansoura Faculty of Medicine, Mansoura, Egypt
    Hematology 9:351-6. 2004
    ..It also appears that the mechanism controlling sTPO levels might be different in cirrhotic patients compared to Bilharzial hepatic fibrosis patients...
  19. ncbi request reprint Accelerated neutrophil apoptosis in neutropenic patients with hepatosplenic schistosomiasis is induced by serum Fas ligand
    Salah Aref
    Hematology Department, Mansoura Faculty of Medicine, Mansoura, Egypt
    Hematol J 5:434-9. 2004
    ..These findings suggest that enhanced neutrophil apoptosis demonstrated in HS patients is triggered by soluble Fas ligand, which is mostly derived from spleen...
  20. ncbi request reprint Assessment of bcl-2 expression as modulator of fas mediated apoptosis in acute leukemia
    S Aref
    Hematology Unit, Clinical Pathology Department, Mansoura Faculty of Medicine Mansoura University Mansoura Egypt
    Hematology 9:113-21. 2004
    ....
  21. ncbi request reprint The interplay between c-Myc oncogene expression and circulating vascular endothelial growth factor (sVEGF), its antagonist receptor, soluble Flt-1 in diffuse large B cell lymphoma (DLBCL): relationship to patient outcome
    S Aref
    Hematology Unit, Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura, Egypt
    Leuk Lymphoma 45:499-506. 2004
    ..9, 35.7, 29.3, 2.63; P < 0.0001, P < 0.0001, and P = 0.03 respectively)..
  22. ncbi request reprint Assessment of neutrophil apoptosis ex vivo in hepatosplenic patients with neutropenia pre and post splenectomy
    Salah E Aref
    Hematology Department, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt
    Hematology 8:265-72. 2003
    ..05, P=0.01 respectively). Serum TNF alpha, IL-3, and IFN gamma levels were not significantly different in all studied groups...
  23. ncbi request reprint Prognostic cytogenetic markers in childhood acute lymphoblastic leukemia: cases from Mansoura Egypt
    A Settin
    Genetic Unit, Mansoura University Children s Hospital, Mansoura, Egypt
    Hematology 12:103-11. 2007
    ..Our conclusions were that cytogenetic and molecular characterizations of childhood ALL could add prognostic criteria for proper therapy allocation...
  24. ncbi request reprint L and E selectins in acute myeloid leukemia: expression, clinical relevance and relation to patient outcome
    S Aref
    Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt
    Hematology 7:83-7. 2002
    ..Moreover, patients with higher sE and sL selectins levels had shorter event free survival than patients with lower levels (P<0.001 for both). The overall mortality prediction using sE, sL, and cellular L selectin was 96%...
  25. ncbi request reprint Soluble hepatocyte growth factor (sHGF) and vascular endothelial growth factor (sVEGF) in adult acute myeloid leukemia: relationship to disease characteristics
    S Aref
    Clinical Pathology Department, Hematology Unit, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt
    Hematology 7:273-9. 2002
    ..Assessment of sHGF at AML diagnosis is likely to be helpful in predicting patient outcome and selecting optimal therapeutic regimen...
  26. ncbi request reprint c-Myc oncogene and Cdc25A cell activating phosphatase expression in non-Hodgkin's lymphoma
    S Aref
    Hematology Unit, Clinical Pathology Department, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egipt
    Hematology 8:183-90. 2003
    ..Assessments of c-Myc and Cdc25A expression in NHL at diagnosis are likely to be helpful in predicting patient outcome and selecting optimal therapeutic regimen...