Biweekly gemcitabine (GEM) in combination with erlotinib (ERL): an active and convenient regimen for advanced pancreatic cancerAlexandros Ardavanis
First Department of Medical Oncology, St Savvas Anticancer Hospital, Athens, Greece
Anticancer Res 29:5211-7. 2009
..The secondary aim was to record treatment related toxicities...
- Non-allergic nature of docetaxel-induced acute hypersensitivity reactions
A Ardavanis
First Department of Medical Oncology and Laboratory of Nuclear Medicine, St Savas Anticancer Hospital, Athens, Greece
Anticancer Drugs 15:581-5. 2004
..If the former is demonstrated by further study, the safety of DT administration will be confirmed, and the pre- and post-medication practice might be revisited...
- Bevacizumab added to the irinotecan and capecitabine combination for advanced colorectal cancer: a well-tolerated, active and convenient regimen
Alexandros Ardavanis
First Department of Medical Oncology, St Savvas Anticancer Hospital, Athens, Greece
Anticancer Res 28:3087-92. 2008
..The safety and efficacy of the addition of BEV to the IRI and CAP (XELIRI) regimen were retrospectively analyzed and reported...
- Erlotinib monotherapy in patients with advanced non-small cell lung cancer: an effective approach with low toxicity
Alexandros Ardavanis
First Department of Medical Oncology, St Savvas Anticancer Hospital, Athens, Greece
Anticancer Res 28:2409-15. 2008
..This retrospective study was conducted to assess the efficacy of erlotinib and its impact on survival...
Trastuzumab plus paclitaxel or docetaxel in HER-2-negative/HER-2 ECD-positive anthracycline- and taxane-refractory advanced breast cancerAlexandros Ardavanis
First Department of Medical Oncology, Saint Savas Oncology Hospital, 171 Alexandras Avenue, 115 22 Athens, Hellas
Oncologist 13:361-9. 2008
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- Low-dose capecitabine in breast cancer patients with symptomatic bone marrow infiltration: a case study
A Ardavanis
First Department of Medical Oncology, Aghios Savvas Anticancer Hospital, Athens, Greece
Anticancer Res 28:539-41. 2008
..The aim of treatment to these patients is palliation. In this study, we sought to determine the efficacy of therapy with low doses of capecitabine in this subgroup of patients...
- Gemcitabine and oral vinorelbine as salvage treatment in patients with advanced anthracycline- and taxane-pretreated breast cancer
A Ardavanis
First Department of Medical Oncology, Ag Savvas Anticancer Hospital, Athens, Greece
Anticancer Res 27:2989-92. 2007
..We sought to determine the efficacy of gemcitabine (GC) and oral vinorelbine (VB) in heavily preatreated ABC...
- Paraneoplastic cerebellar degeneration in a patient with pseudomyxoma peritonei and breast cancer: case report and literature review
Alexandros Ardavanis
First Department of Medical Oncology, Athens, Greece
In Vivo 23:835-8. 2009
..Early recognition and appropriate therapy of this rare complication of PMP is imperative as it may be crucial for the outcome...
- Skin metastases from primary lung cancer. Report of three cases and a brief review
Alexandros Ardavanis
First Department of Medical Oncology, St Savvas Anticancer Hospital, Athens, Greece
In Vivo 20:671-3. 2006
..The eventual association of skin metastases and a phenotype with "CNS-predilection" or an aggressive phase of NSCLC are discussed...
- Multidisciplinary therapy of locally far-advanced or inflammatory breast cancer with fixed perioperative sequence of epirubicin, vinorelbine, and Fluorouracil chemotherapy, surgery, and radiotherapy: long-term results
Alexandros Ardavanis
First Department of Medical Oncology, St Savas Anticancer Hospital, 171 Alexandras Avenue, 115 22 Athens, Greece
Oncologist 11:563-73. 2006
..Based on phase II data in advanced breast cancer (BC), the fluorouracil, epirubicin, and vinorelbine (FEN) combination was assessed as perioperative chemotherapy, integrated in a multidisciplinary treatment for locally advanced BC...
- Salvage treatment with single-agent capecitabine in patients with heavily pretreated advanced colorectal cancer
Alexandros S Ardavanis
St Savas Anticancer Oncologic Hospital, First Department of Medical Oncology, Athens, Greece
Anticancer Res 26:1669-72. 2006
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- First-line chemotherapy with fluorouracil-epirubicin-navelbine (FEN) combination in advanced breast cancer
A Ardavanis
First Department of Medical Oncology, St Savas Anticancer Hospital, Athens, Greece
Anticancer Res 25:4493-8. 2005
..A phase II study was carried out to determine the safety and efficacy of the combination of vinorelbine, epirubicin and 5-fluorouracil (FEN) as first-line chemotherapy in advanced breast cancer (BC)...
- Safety and efficacy of trastuzumab every 3 weeks combined with cytotoxic chemotherapy in patients with HER2-positive recurrent breast cancer: findings from a case series
Alexandros Ardavanis
First Department of Medical Oncology, St Savas Anticancer Hospital, Athens, Greece
Onkologie 28:558-64. 2005
..Trastuzumab is currently licensed as a weekly treatment, although a 3-weekly schedule could be used conveniently in combination with other cytotoxic agents that are administered on a 3-weekly basis in metastatic breast cancer...
- Acute myopathy in a patient with lung adenocarcinoma treated with gemcitabine and docetaxel
Alexandros S Ardavanis
First Department of Medical Oncology, St Savas Anticancer Oncologic Hospital, Athens, Greece
Anticancer Res 25:523-5. 2005
..The syndrome regressed definitely after the discontinuation of chemotherapy and the administration of corticosteroids. The diagnosis of drug-induced myositis is supported after the exclusion of other possible diagnoses...
Gemcitabine and docetaxel as first-line treatment for advanced urothelial carcinoma: a phase II studyA Ardavanis
1st Department of Medical Oncology, St Savas Anticancer Hospital, 171 Alexandras Avenue, 11522 Athens, Greece
Br J Cancer 92:645-50. 2005
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- Bevacizumab combined with two-weekly paclitaxel as first-line therapy for metastatic breast cancer
Panteleimon Kountourakis
First Department of Medical Oncology, St Savas Anticancer Hospital, 171 Alexandras Avenue, 11522 Athens, Greece
Anticancer Res 30:2969-71. 2010
..Herein, this study sought to investigate an alternative bevacizumab-taxane regimen as first-line treatment for metastatic breast cancer...
- Clinical significance of kallikrein-related peptidase 7 (KLK7) in colorectal cancer
Maroulio Talieri
Department of Cellular Physiology, G Papanicolaou Research Center of Oncology, Saint Savas Hospital, Athens, Greece
Thromb Haemost 101:741-7. 2009
..Present data suggest that KLK7 gene is up-regulated in colon cancer and its expression predicts poor prognosis for colon cancer patients...
- CD4+CD25+ regulatory T-cell frequency in HER-2/neu (HER)-positive and HER-negative advanced-stage breast cancer patients
Sonia A Perez
Cancer Immunology and Immunotherapy Center, Saint Savas Cancer Hospital, Athens, Greece
Clin Cancer Res 13:2714-21. 2007
..Circulating Tregs in correlation with HER-2/neu (HER) status and treatment with chemotherapy, either alone or in combination with trastuzumab therapy, were monitored in advanced-stage breast cancer patients...
- Salvage therapy of pretreated advanced breast cancer with bevacizumab and paclitaxel every two weeks: a retrospective case review study
Alexandros Ardavanis
Department of Medical Oncology, St Savas Anticancer Hospital, Athens, Greece
BMC Cancer 9:338. 2009
..The activity of this combination in pretreated patients is not known...
- Comparison of HER2 detection methods between central and regional laboratories in Greece
Savvas Papadopoulos
Department of Pathology, Hygeia Hospital Harvard Medical International, Maroussi, Athens, Greece
Clin Breast Cancer 7:784-90. 2007
..This study compares immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) HER2 testing at central and regional laboratories in Greece...
- A phase I trial of adoptive transfer of allogeneic natural killer cells in patients with advanced non-small cell lung cancer
Eleni G Iliopoulou
Cancer Immunology and Immunotherapy Center, Saint Savas Cancer Hospital, 171 Alexandras Avenue, 115 22, Athens, Greece
Cancer Immunol Immunother 59:1781-9. 2010
..In conclusion, repetitive infusions of allogeneic, in vitro activated and expanded with IL-15/HC NK cells, in combination with chemotherapy are safe and potentially clinically effective...
- Systemic sclerosis associated with rectal cancer. Case report and a brief review of the literature
George Orphanos
First Department of Medical Oncology, Ag Savvas Anticancer Hospital, Athens, Greece
In Vivo 22:825-9. 2008
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- Increased frequency of CD4+ cells expressing CD161 in cancer patients
Eleni G Iliopoulou
Cancer Immunology and Immunotherapy Center, Saint Savas Cancer Hospital, Athens, Greece
Clin Cancer Res 12:6901-9. 2006
..Depending on the type of signals provided by the tumor microenvironment, CD4(+)CD161(+) cells may regulate the immune response...
