Trends in cervical cancer incidence and mortality in Bulgaria, Estonia, Latvia, Lithuania and RomaniaMarc Arbyn
Unit of Cancer Epidemiology Scientific Institute of Public Health, Brussels, Belgium
Tumori 96:517-23. 2010
..The burden of cervical cancer varies considerably in the European Union. In this paper, we describe trends in incidence of and mortality from this cancer in the five most affected member states...
Cytological screening for cervical cancer in the province of Limburg, BelgiumMarc Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, Brussels, Belgium
Eur J Cancer Prev 20:18-24. 2011
..Obligatory registration, use of a uniform terminology and linkage with population and follow-up data are needed to give a cytology registry its full role in an organized screening programme...
- Cervical cytology biobanking in Europe
Marc Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, Brussels, Belgium
Int J Biol Markers 25:117-25. 2010
..To understand the limitations of CCB, more studies are needed on the quality of samples in relation to sample type, storage procedures, and duration of storage...
- Evidence regarding human papillomavirus testing in secondary prevention of cervical cancer
Marc Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, Brussels, Belgium
Vaccine 30:F88-99. 2012
..This article forms part of a special supplement entitled "Comprehensive Control of HPV Infections and Related Diseases" Vaccine Volume 30, Supplement 5, 2012...
- The APTIMA HPV assay versus the Hybrid Capture 2 test in triage of women with ASC-US or LSIL cervical cytology: a meta-analysis of the diagnostic accuracy
Marc Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, Brussels, Belgium
Int J Cancer 132:101-8. 2013
..35; 95% CI = 1.11-1.66). Results were similar for detection of CIN2 or worse. In both triage of ASC-US and LSIL, APTIMA is as sensitive but more specific than HC2 for detecting cervical precancer...
EUROGIN 2011 roadmap on prevention and treatment of HPV-related diseaseMarc Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, Brussels, Belgium
Int J Cancer 131:1969-82. 2012
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- Worldwide burden of cervical cancer in 2008
M Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, Brussels, Belgium
Ann Oncol 22:2675-86. 2011
..Up-to-date and reliable data are needed to assess impact of existing preventive measures and to define priorities for the future...
- Trends in cervical cancer incidence and mortality in the Baltic countries, Bulgaria and Romania
Marc Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, Brussels, Belgium
Int J Cancer 128:1899-907. 2011
..Rising trends of cervical cancer in the most affected EU member states reveal a worrying pattern that warrants urgent preventive actions...
- Virologic versus cytologic triage of women with equivocal Pap smears: a meta-analysis of the accuracy to detect high-grade intraepithelial neoplasia
Marc Arbyn
European Network for Cervical Cancer Screening and Unit for Evaluation of Cancer Screening Programmes, Scientific Institute of Public Health, Brussels, Belgium
J Natl Cancer Inst 96:280-93. 2004
..We performed a meta-analysis to assess the accuracy of human papillomavirus (HPV) DNA testing as an alternative to repeat cytology in women who had equivocal results on a previous Pap smear...
- p16INK4a immunocytochemistry versus human papillomavirus testing for triage of women with minor cytologic abnormalities: a systematic review and meta-analysis
Jolien Roelens
Unit of Cancer Epidemiology, Scientific Institute of Public Health, Brussels, Belgium
Cancer Cytopathol 120:294-307. 2012
..74 [95% CI, 1.99-3.76]). The published literature indicated the improved accuracy of p16(INK4a) compared with HC2 testing in the triage of women with ASC-US. In LSIL triage, p16(INK4a) was more specific but less sensitive...
- Chapter 9: Clinical applications of HPV testing: a summary of meta-analyses
Marc Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, J Wytsmanstreet 14, Brussels, Belgium
Vaccine 24:S3/78-89. 2006
..More than ever, clinicians need regularly updated reviews given the continuously increasing amount of new information regarding innovative cervical cancer prevention methods...
- Triage of women with equivocal or low-grade cervical cytology results: a meta-analysis of the HPV test positivity rate
Marc Arbyn
Scientific Institute of Public Health, Brussels, Belgium
J Cell Mol Med 13:648-59. 2009
..Research is needed to identify more specific methods to triage women with low-grade squamous cervical lesions...
- Cervical cytology biobanks as a resource for molecular epidemiology
Marc Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, Brussels, Belgium
Methods Mol Biol 675:279-98. 2011
..To understand the limitations of CCB, more studies are needed on quality of samples in relation to sample type, storage procedures, and duration of storage...
- Pooled analysis of the accuracy of five cervical cancer screening tests assessed in eleven studies in Africa and India
Marc Arbyn
Scientific Institute of Public Health, Unit of Cancer Epidemiology, Brussels, Belgium
Int J Cancer 123:153-60. 2008
..Gold standard verification error could also explain the surprisingly low sensitivity of HC2, which contrasts with findings from other studies...
- Trends of cervical cancer mortality in the member states of the European Union
Marc Arbyn
Belgian Cancer Centre, Scientific Institute of Public Health, Brussels, Belgium
Eur J Cancer 45:2640-8. 2009
..In the current paper, we analyse cervical cancer mortality trends in the 27 member states since 1970 and, subsequently, try to explain how screening and other factors have driven changes...
- Prevaccination distribution of human papillomavirus types in women attending at cervical cancer screening in Belgium
Marc Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, J Wytsmanstreet 14, BE 1050 Brussels, Belgium
Cancer Epidemiol Biomarkers Prev 18:321-30. 2009
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- Liquid compared with conventional cervical cytology: a systematic review and meta-analysis
Marc Arbyn
Scientific Institute of Public Health, Brussels, Belgium
Obstet Gynecol 111:167-77. 2008
..To compare test performance characteristics of conventional Pap tests and liquid-based cervical cytology samples...
- Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions
Marc Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, Juliette Wytsmanstreet 14, Brussels, Belgium, B 1050
Cochrane Database Syst Rev 3:CD008054. 2013
..This review evaluates two ways to triage women with ASCUS or LSIL: repeating the cytological test, and DNA testing for high-risk types of the human papillomavirus (hrHPV) - the main causal factor of cervical cancer...
- How to evaluate emerging technologies in cervical cancer screening?
Marc Arbyn
Unit of Cancer Epidemiology Belgian Cancer Centre, Scientific Institute of Public Health, Brussels, Belgium
Int J Cancer 125:2489-96. 2009
..The 5-phases framework should guide researchers and test developers in planning assessment of new biomarkers and protect clinicians and stakeholders against premature claims for insufficiently evaluated products...
- The challenges of organising cervical screening programmes in the 15 old member states of the European Union
Marc Arbyn
Unit of Cancer Epidemiology and Belgian Cancer Centre, Scientific Institute of Public Health, Brussels, Belgium
Eur J Cancer 45:2671-8. 2009
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- Analysis of 13 million individual patient records pertaining to Pap smears, colposcopies, biopsies and surgery on the uterine cervix (Belgium, 1996-2000)
Marc Arbyn
Belgian Cancer Center Unit of Cancer Epidemiology, Scientific Institute of Public Health, J Wytsman Street 14, Brussels, Belgium
Prev Med 48:438-43. 2009
..Cervical cancer screening by surveys overestimate coverage because of selection and reporting biases...
- The burden of cervical cancer in south-east Europe at the beginning of the 21st century
Marc Arbyn
Scientific Institute of Public Health, Unit of Cancer Epidemiology, Brussels, Belgium
Coll Antropol 31:7-10. 2007
..Thus, appropriate cervical cancer prevention programmes should be set up without delay in this part of Europe...
- Belgian Parliament calls for organised cervical cancer screening and HPV research throughout Europe
Marc Arbyn
European Network of Cervical Cancer Screening, Scientific Institute of Public Health, Brussels, Belgium
Lancet Oncol 3:74. 2002
- Review of current knowledge on HPV vaccination: an appendix to the European Guidelines for Quality Assurance in Cervical Cancer Screening
Marc Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, Brussels, Belgium
J Clin Virol 38:189-97. 2007
..The purpose of the appendix on vaccination is to present current knowledge. Developing guidelines for future use of HPV vaccines in Europe, is the object of a new grant offered by the European Commission...
- Impact of genetic notification on smoking cessation: systematic review and pooled-analysis
Sylviane de Viron
Operational Direction Public Health and Surveillance, Scientific Institute of Public Health, Brussels, Belgium
PLoS ONE 7:e40230. 2012
..Secondary objectives were to assess the impact of genetic notification on intention-to-quit smoking and on emotional outcomes as well as the understanding and the recall of this notification...
- International agreement to join forces in synthesizing evidence on new methods for cervical cancer prevention
Marc Arbyn
Unit of Cancer Epidemiology, Scientific Institute of Public Health, Brussels, Belgium
Cancer Lett 278:1-2. 2009
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- Metaanalysis of the accuracy of rapid prescreening relative to full screening of pap smears
Marc Arbyn
Scientific Institute of Public Health, Brussels, Belgium
Cancer 99:9-16. 2003
..In a previous study, we pooled data on the diagnostic quality of rapid reviewing (RR) of cervical smears initially reported as normal or unsatisfactory. We now focus on rapid prescreening (RPS) of unreported smears...
- Trend of cervical cancer mortality in Belgium (1954-1994): tentative solution for the certification problem of unspecified uterine cancer
Marc Arbyn
Department of Epidemiology, Scientific Institute of Public Health, Brussels, Belgium
Int J Cancer 102:649-54. 2002
..The tendency of increasing mortality in women born after 1935 required particular attention. Nevertheless, the slope of the corrected recent cohort effect remained limited in Belgium, probably as a consequence of screening...
- Transmission of carcinogenic human papillomavirus types from mother to child: a meta-analysis of published studies
Mireille Merckx
Department of Gynaecology, University Hospital, Scientific Institute for Public Health, Brussels, Belgium
Eur J Cancer Prev 22:277-85. 2013
..More research is required to gain an insight into the precise mode of transmission and the clinical effects of infection on the child...
