Efficacy and tolerability of prostaglandin-timolol fixed combinations: a meta-analysis of randomized clinical trialsFlorent Aptel
Department of Ophthalmology, Edouard Herriot Hospital, Lyon, France
Eur J Ophthalmol 22:5-18. 2012
..To evaluate the intraocular pressure (IOP)-lowering effects and tolerability of the 3 prostaglandin-timolol fixed combinations (PG-timolol FCs)...
- Miniaturized high-intensity focused ultrasound device in patients with glaucoma: a clinical pilot study
Florent Aptel
Department of Ophthalmology, Hospices Civils de Lyon, Hopital Edouard Herriot, Lyon, France
Invest Ophthalmol Vis Sci 52:8747-53. 2011
..To evaluate the relative safety and potential efficacy of high-intensity focused ultrasound cyclocoagulation by a miniaturized annular device containing six piezoceramic transducers in patients with refractory glaucoma...
- Efficacy and tolerability of prostaglandin analogs: a meta-analysis of randomized controlled clinical trials
Florent Aptel
Department of Ophthalmology, Edouard Herriot Hospital, Lyon, France
J Glaucoma 17:667-73. 2008
..This systematic meta-analysis was performed to evaluate the intraocular pressure (IOP) lowering effects and tolerability of latanoprost, bimatoprost, and travoprost...
- Balancing efficacy and tolerability of prostaglandin analogues and prostaglandin-timolol fixed combinations in primary open-angle glaucoma
F Aptel
Department of Ophthalmology, Edouard Herriot Hospital, Lyon 1 University, France
Curr Med Res Opin 27:1949-58. 2011
..Similarly, PGA-based fixed combinations are frequently used in patients who progress or fail to achieve the target IOP...
- Biometric analysis of pigment dispersion syndrome using anterior segment optical coherence tomography
Florent Aptel
Hospices Civils de Lyon, Department of Ophthalmology, Hopital Edouard Herriot, Lyon, France
Ophthalmology 118:1563-70. 2011
....
- [Managing treatment side effects: the respective roles of the active ingredient and the preservative]
F Aptel
Service d Ophtalmologie, Hospices Civils de Lyon, Hopital Edouard Herriot, 5, Place d Arsonval, 69437 Lyon Cedex 03, France
J Fr Ophtalmol 34:409-12. 2011
..When available, preservative-free solutions should be considered...
- [Risk factors of glaucoma progression: intraocular pressure fluctuations]
F Aptel
Service d Ophtalmologie, Hospices Civils de Lyon, Hopital Edouard Herriot, 5, Place d Arsonval, 69437 Lyon Cedex 03, France
J Fr Ophtalmol 34:400-2. 2011
..Nevertheless, it is important for each patient to estimate the short-term and long-term fluctuations and to prioritize a treatment that minimizes these fluctuations...
- Structure-function relationships using spectral-domain optical coherence tomography: comparison with scanning laser polarimetry
Florent Aptel
Department of Ophthalmology, Edouard Herriot Hospital, Lyon 1 University, Lyon, France
Am J Ophthalmol 150:825-33. 2010
..To evaluate and compare the regional relationships between visual field sensitivity and retinal nerve fiber layer (RNFL) thickness as measured by spectral-domain optical coherence tomography (OCT) and scanning laser polarimetry...
- Histologic effects of a new device for high-intensity focused ultrasound cyclocoagulation
Florent Aptel
INSERM, U556, Lyon, France
Invest Ophthalmol Vis Sci 51:5092-8. 2010
..To evaluate the histologic effects and clinical outcomes of high-intensity focused ultrasound (HIFU) delivered by miniaturized annular transducers for ciliary body coagulation in an animal study...
Ultrasound biomicroscopy and optical coherence tomography imaging of filtering blebs after deep sclerectomy with new collagen implantFlorent Aptel
Department of Ophthalmology, Edouard Herriot Hospital, Lyon France
Eur J Ophthalmol 19:223-30. 2009
....
- Development of a miniaturized HIFU device for glaucoma treatment with conformal coagulation of the ciliary bodies
Thomas Charrel
INSERM, U556, Universite de Lyon, Lyon, France
Ultrasound Med Biol 37:742-54. 2011
..In vivo experiments were conducted on two rabbits. A significant intraocular pressure reduction was noted (-45% and -31%). Histology demonstrated conformal and homogeneous coagulation of the CB without side effects...
- Optical coherence tomography quantitative analysis of iris volume changes after pharmacologic mydriasis
Florent Aptel
Department of Ophthalmology, Edouard Herriot Hospital, Lyon 1 University, Lyon, France
Ophthalmology 117:3-10. 2010
..To quantify changes in iris volume induced by pharmacologic mydriasis in narrow-angle eyes predisposed to angle-closure compared with normal open-angle eyes...
- Therapeutic applications of ultrasound in ophthalmology
Florent Aptel
INSERM, U1032, Lyon, F 69003, France
Int J Hyperthermia 28:405-18. 2012
..The aim of this contribution is to provide an update on recent advances in the field of therapeutic ultrasound in ophthalmology...
- Efficacy and tolerability of prostaglandin-timolol fixed combinations: a meta-analysis of randomized clinical trials
Florent Aptel
Department of Ophthalmology, Edouard Herriot Hospital, Lyon France
Eur J Ophthalmol 22:5-18. 2012
..The direct comparisons suggest a greater efficacy of the bimatoprost-timolol FC compared with latanoprost- and travoprost-timolol FCs...
