Chittaranjan Andrade

Summary

Publications

  1. doi request reprint A primer on confidence intervals in psychopharmacology
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 76:e228-31. 2015
  2. doi request reprint Ondansetron augmentation of serotonin reuptake inhibitors as a treatment strategy in obsessive-compulsive disorder
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 76:e72-5. 2015
  3. doi request reprint The safety of duloxetine during pregnancy and lactation
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e1423-7. 2014
  4. doi request reprint Fruit juice, organic anion transporting polypeptides, and drug interactions in psychiatry
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e1323-5. 2014
  5. doi request reprint A critical examination of studies on curcumin for depression
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e1110-2. 2014
  6. doi request reprint Antidepressant augmentation with anti-inflammatory agents
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:975-7. 2014
  7. doi request reprint Cause versus association in observational studies in psychopharmacology
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e781-4. 2014
  8. doi request reprint Nonsteroidal anti-inflammatory drugs and 5-HT₃ serotonin receptor antagonists as innovative antipsychotic augmentation treatments for schizophrenia
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e707-9. 2014
  9. doi request reprint A primer for the conceptualization of the mechanism of action of electroconvulsive therapy, 2: organizing the information
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e548-51. 2014
  10. doi request reprint A primer for the conceptualization of the mechanism of action of electroconvulsive therapy, 1: defining the question
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e410-2. 2014

Collaborators

Detail Information

Publications47

  1. doi request reprint A primer on confidence intervals in psychopharmacology
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 76:e228-31. 2015
    ..The significance of overlapping and nonoverlapping CIs is considered. It is concluded that CIs are far more informative than, say, mere P values when drawing conclusions about a result. ..
  2. doi request reprint Ondansetron augmentation of serotonin reuptake inhibitors as a treatment strategy in obsessive-compulsive disorder
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 76:e72-5. 2015
    ..At best, ondansetron (1-8 mg/d) may be considered an experimental SRI augmentation agent in OCD patients for whom augmentation with an atypical antipsychotic drug is problematic. ..
  3. doi request reprint The safety of duloxetine during pregnancy and lactation
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e1423-7. 2014
    ..In general, the very limited data available on the subject do not uncover a signal that the use of duloxetine during pregnancy or lactation increases the risk of adverse outcomes. ..
  4. doi request reprint Fruit juice, organic anion transporting polypeptides, and drug interactions in psychiatry
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e1323-5. 2014
    ....
  5. doi request reprint A critical examination of studies on curcumin for depression
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e1110-2. 2014
    ..At present, therefore, there is insufficient evidence to encourage depressed patients to consider curcumin as a possible alternative to standard antidepressant therapy. ..
  6. doi request reprint Antidepressant augmentation with anti-inflammatory agents
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:975-7. 2014
    ..A reasonable conclusion for the present is that NSAID augmentation of antidepressants is, at best, a tentative approach in nonrefractory major depression. ..
  7. doi request reprint Cause versus association in observational studies in psychopharmacology
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e781-4. 2014
    ..As a conclusion of this exercise, clinicians are cautioned against placing too much reliance on the findings of observational research. ..
  8. doi request reprint Nonsteroidal anti-inflammatory drugs and 5-HT₃ serotonin receptor antagonists as innovative antipsychotic augmentation treatments for schizophrenia
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e707-9. 2014
    ..Both fields of inquiry require further investigation. ..
  9. doi request reprint A primer for the conceptualization of the mechanism of action of electroconvulsive therapy, 2: organizing the information
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e548-51. 2014
    ..Organizing information in this manner can help explain both efficacy and adverse effects of ECT. Brief explanations are provided. ..
  10. doi request reprint A primer for the conceptualization of the mechanism of action of electroconvulsive therapy, 1: defining the question
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e410-2. 2014
    ..This article presents a primer for the conceptualization of the mechanism of action of ECT with special attention to understanding why the question and answer are complex. ..
  11. doi request reprint Potentially significant versus clinically significant drug interactions: pomegranate juice as a case in point
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e292-3. 2014
    ....
  12. doi request reprint Antidepressants and testicular cancer: cause versus association
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e198-200. 2014
    ....
  13. doi request reprint Selective serotonin reuptake inhibitor drug interactions in patients receiving statins
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 75:e95-9. 2014
    ..Risk, if at all, lies in combining fluvoxamine with atorvastatin, simvastatin, or lovastatin, and even this risk can be minimized by using lower statin doses and monitoring the patient. ..
  14. doi request reprint Augmenting selective serotonin reuptake inhibitors with clomipramine in obsessive-compulsive disorder: benefits and risks
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 74:e1128-33. 2013
    ..This article presents an evidence-based discussion of the pharmacodynamic and pharmacokinetic adverse effects of the SSRI-clomipramine combination along with suggestions for dosing and monitoring when the combination is used in OCD. ..
  15. doi request reprint Transcranial direct current stimulation for refractory auditory hallucinations in schizophrenia
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 74:e1054-8. 2013
    ..Transcranial direct current stimulation therefore appears to be a promising noninvasive brain stimulation technique for patients with antipsychotic-refractory auditory hallucinations. ..
  16. ncbi request reprint Drugs that escape hepatic metabolism
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 73:e889-90. 2012
    ..This article considers anxiolytic, antidepressant, antipsychotic, mood stabilizer, anticonvulsant, and anti-dementia drugs that are useful in such situations. A few metabolic drug interactions are briefly discussed...
  17. doi request reprint Schizophrenia and smoking
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 73:e725-7. 2012
    ..The article concludes with a discussion of other pharmacokinetic considerations related to smoking and its treatment in patients with schizophrenia...
  18. doi request reprint Celecoxib as an in vivo probe of cyclooxygenase-2 mechanisms underlying retrograde amnesia in an animal model of ECT
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    J Neural Transm 115:1063-70. 2008
    ..Electroconvulsive therapy (ECT)-induced amnesia may arise from glutamatergic excitotoxicity; if so, COX-2 inhibition may attenuate retrograde amnesia with ECT...
  19. ncbi request reprint Possible glutamatergic and lipid signalling mechanisms in ECT-induced retrograde amnesia: experimental evidence for involvement of COX-2, and review of literature
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Psychiatr Res 42:837-50. 2008
    ..These findings suggest new avenues for the study of the neurobiology of ECT-induced amnesia and the attenuation thereof...
  20. ncbi request reprint Glucocorticoid mechanisms may contribute to ECT-induced retrograde amnesia
    Nandakumar Nagaraja
    Department of Pharmacology, St John s Medical College, Bangalore, India
    Psychopharmacology (Berl) 190:73-80. 2007
    ..Steroid mechanisms may therefore modulate ECT-induced amnesia...
  21. doi request reprint The depiction of electroconvulsive therapy in Hindi cinema
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore
    J ECT 26:16-22. 2010
    ..There is little literature on the depiction of electroconvulsive therapy (ECT) in movies. In India, Hindi cinema is an important source of public information and misinformation about ECT...
  22. ncbi request reprint Confirmation of whole-brain kindling with repeated subthreshold electroconvulsive shocks: a controlled study
    Chittaranjan Andrade
    Department of Psychopharmacology and dagger Central Animal Research Facility, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 19:81-3. 2003
    ..It is not known, however, whether this kindling results from the repeated subconvulsive stimulation or from the stress induced by the experimental procedures...
  23. ncbi request reprint Spectral EEG effects of electroconvulsive shock stimulus parameters: the development of a rationale for the optimization of the ECT stimulus
    S Sudha
    Department of Pharmacology, St John s Medical College, Bangalore, India
    J ECT 19:197-210. 2003
    ..We examined the influence of these parameters on the EEG power spectrum in an animal model...
  24. ncbi request reprint Schizophrenia, osteoporosis, and an examination of the risk of fractures in patients receiving ECT
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 23:219-20. 2007
  25. doi request reprint Once- to twice-daily, 3-year domiciliary maintenance transcranial direct current stimulation for severe, disabling, clozapine-refractory continuous auditory hallucinations in schizophrenia
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 29:239-42. 2013
    ..Some patients with schizophrenia suffer from continuous auditory hallucinations that are refractory to antipsychotic medications...
  26. doi request reprint Images in electroconvulsive therapy: electroconvulsive shocks dose-dependently increase dendritic arborization in the CA1 region of the rat hippocampus
    Jangama S M Smitha
    From the Department of Anatomy, St John s Medical College and Departments of Neurophysiology and Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 30:191-2. 2014
    ..These neuroplasticity changes, identified 1 month after the last ECS, may explain a part of the mechanism of action of electroconvulsive therapy in conditions such as depression. ..
  27. ncbi request reprint ECT: a measured defence
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Issues Med Ethics 11:44-6. 2003
  28. ncbi request reprint Controversy revisited: Selective serotonin reuptake inhibitors in paediatric depression
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    World J Biol Psychiatry 7:251-60. 2006
    ..There have been several publications on the subject during recent years. This article summarizes their findings and provides some original thoughts, suggestions, and perspectives...
  29. ncbi request reprint Unilateral nondominant electrode placement as a risk factor for recall of awareness under anesthesia during electroconvulsive therapy
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 23:201-3. 2007
    ..Awareness under anesthesia can be a frightening experience for patients receiving electroconvulsive therapy (ECT)...
  30. ncbi request reprint Unmodified ECT: ethical issues
    Chittaranjan Andrade
    National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Issues Med Ethics 11:9-10. 2003
  31. ncbi request reprint The dilemma of unmodified electroconvulsive therapy
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    J Clin Psychiatry 64:1147-52. 2003
  32. ncbi request reprint ECS seizure threshold: normal variations, and kindling effects of subconvulsive stimuli
    Singaravelu Kurinji
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 19:31-7. 2003
    ..We sought to examine the variability of the electroconvulsive shock (ECS) seizure threshold in rats, and to identify factors influencing the threshold, to guide future research using animal models...
  33. doi request reprint Images in electroconvulsive therapy: ECS dose-dependently increases cell proliferation in the subgranular region of the rat hippocampus
    Jangama S M Smitha
    From the Department of Anatomy, St John s Medical College Departments of Neuropathology, Neurophysiology, and Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 30:193-4. 2014
    ..These neuroplasticity changes, demonstrated 1 month after the last ECS, may explain a part of the mechanism of action of electroconvulsive therapy in conditions such as depression. ..
  34. ncbi request reprint Antidepressant-withdrawal mania:a critical review and synthesis of the literature
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Clin Psychiatry 65:987-93. 2004
    ..This article examines the possible etiology, nosology, mechanisms, and other aspects of the syndrome...
  35. ncbi request reprint The influence of name on the acceptability of ECT: the importance of political correctness
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 23:75-7. 2007
    ..Attitudes toward a treatment influence the acceptability of the treatment. There has been no study of how attitudes toward electroconvulsive therapy (ECT) are influenced by what ECT is called...
  36. pmc Systematic enhancement of functioning as a therapeutic technique in conversion disorder
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Indian J Psychiatry 51:134-6. 2009
    ..The technique outlined is simple and practical but nevertheless receives no mention in conversion disorder literature. The technique can be applied to any situation in which behavioral amplification is desired...
  37. doi request reprint Antipsychotic augmentation with modafinil or armodafinil for negative symptoms of schizophrenia: systematic review and meta-analysis of randomized controlled trials
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India Electronic address
    J Psychiatr Res 60:14-21. 2015
    ..Ar/mod does not benefit or worsen other symptom dimensions in schizophrenia...
  38. ncbi request reprint Continuation and maintenance ECT: a review of recent research
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosiences, Bangalore, India
    J ECT 18:149-58. 2002
    ....
  39. ncbi request reprint A randomized, double-blind comparison of lorazepam and chlordiazepoxide in patients with uncomplicated alcohol withdrawal
    Channaveerachari Naveen Kumar
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Stud Alcohol Drugs 70:467-74. 2009
    ..A formal comparison is desirable because of pharmacokinetic and other differences that could affect safety and efficacy considerations relevant to practice in developing countries...
  40. ncbi request reprint Effect of stimulus intensity and number of treatments on ECS-related seizure duration and retrograde amnesia in rats
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 18:197-202. 2002
    ..Although many predictors of ECT-induced amnesia are known, their relative effects have been inadequately researched in the context of the animal models...
  41. doi request reprint Primary prevention of cardiovascular events in patients with major mental illness: a possible role for statins
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    Bipolar Disord 15:813-23. 2013
    ..To examine the need for and the possible benefits and risks of statin therapy in patients with major mental illness...
  42. doi request reprint Electroconvulsive therapy attenuates dendritic arborization in the basolateral amygdala
    Nagarchi Khaleel
    Department of Anatomy, St John s Medical College, Bangalore, India
    J ECT 29:156-7. 2013
    ..These changes may explain a part of the mechanism of action of electroconvulsive therapy in conditions such as depression and posttraumatic stress disorder. ..
  43. pmc Psychopharmacology of schizophrenia: The Future Looks Bleak
    Chittaranjan Andrade
    Professor and Head, Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Mens Sana Monogr 10:4-12. 2012
    ..More than half a century after the introduction of effective pharmacotherapy for the illness, in most patients schizophrenia remains a chronic, relapsing condition with poor long-term outcomes...
  44. doi request reprint Serotonin reuptake inhibitor antidepressants and abnormal bleeding: a review for clinicians and a reconsideration of mechanisms
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    J Clin Psychiatry 71:1565-75. 2010
    ....
  45. pmc Familial vulnerability to an unusual cognitive adverse effect of topiramate: Discussion of mechanisms
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India
    Indian J Psychiatry 52:260-3. 2010
    ..Some patients experience cognitive disturbances with topiramate...
  46. pmc Investigation of the possible role of Shankapushpi in the attenuation of ECT induced amnestic deficits
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychiatry 54:166-71. 2012
    ..This study used an animal model to examine whether Shankapushpi improves learning and memory and attenuates anterograde and retrograde amnesia associated with electroconvulsive shocks (ECS)...
  47. doi request reprint Administration of a selective glucocorticoid antagonist attenuates electroconvulsive shock-induced retrograde amnesia
    Chittaranjan Andrade
    Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    J Neural Transm 119:337-44. 2012
    ....