Mansoor Amiji

Summary

Publications

  1. ncbi request reprint Biodistribution and pharmacokinetics of dapivirine-loaded nanoparticles after vaginal delivery in mice
    José das Neves
    IINFACTS Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Instituto Superior de Ciencias da Saude Norte, CESPU, Rua Central de Gandra, 1317, 4585 116, Gandra, Portugal
    Pharm Res 31:1834-45. 2014
  2. ncbi request reprint Assessing the physical-chemical properties and stability of dapivirine-loaded polymeric nanoparticles
    José das Neves
    CICS Centro de Investigação em Ciências da Saúde, Department of Pharmaceutical Sciences, Instituto Superior de Ciencias da Saude Norte, CESPU, Rua Central de Gandra 1317, 4585 116 Gandra, Portugal Laboratory of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050 313 Porto, Portugal Electronic address
    Int J Pharm 456:307-14. 2013
  3. doi request reprint Interactions of microbicide nanoparticles with a simulated vaginal fluid
    José das Neves
    Laboratory of Pharmaceutical Technology, LTF CICF, Faculty of Pharmacy, University of Porto, Porto, Portugal
    Mol Pharm 9:3347-56. 2012
  4. doi request reprint Development and validation of a HPLC method for the assay of dapivirine in cell-based and tissue permeability experiments
    José das Neves
    Laboratory of Pharmaceutical Technology, LTF CICF, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050 313, Porto, Portugal
    J Chromatogr B Analyt Technol Biomed Life Sci 911:76-83. 2012
  5. doi request reprint Polymeric nanoparticles affect the intracellular delivery, antiretroviral activity and cytotoxicity of the microbicide drug candidate dapivirine
    José das Neves
    Laboratory of Pharmaceutical Technology, LTF CICF Faculty of Pharmacy, University of Porto, Rua Anibal Cunha, 164, 4050 047, Porto, Portugal
    Pharm Res 29:1468-84. 2012
  6. ncbi request reprint Gels as vaginal drug delivery systems
    J das Neves
    Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, Rua Anibal Cunha, 164, 4050 030 Porto, Portugal
    Int J Pharm 318:1-14. 2006
  7. doi request reprint Development and validation of a rapid reversed-phase HPLC method for the determination of the non-nucleoside reverse transcriptase inhibitor dapivirine from polymeric nanoparticles
    José das Neves
    Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, Rua Anibal Cunha 164, 4050 047 Porto, Portugal
    J Pharm Biomed Anal 52:167-72. 2010
  8. ncbi request reprint Rheological properties of vaginal hydrophilic polymer gels
    José das Neves
    Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, Porto, Portugal
    Curr Drug Deliv 6:83-92. 2009
  9. ncbi request reprint Local treatment of vulvovaginal candidosis : general and practical considerations
    José das Neves
    Department of Microbiology, CEQUIMED, Faculty of Pharmacy, University of Porto, Porto, Portugal
    Drugs 68:1787-802. 2008
  10. doi request reprint Performance of an in vitro mucoadhesion testing method for vaginal semisolids: influence of different testing conditions and instrumental parameters
    José das Neves
    Department of Pharmaceutical Technology, Faculty of Pharmacy of the University of Porto, Porto, Portugal
    Eur J Pharm Biopharm 69:622-32. 2008

Collaborators

  • Bruno Sarmento
  • Kevin K Ariën
  • Eugénia Pinto
  • Rebecca L Carrier
  • José das Neves
  • Maria Fernanda Bahia
  • Francisca Araújo
  • Fernanda Andrade
  • Guido Vanham
  • Johan Michiels
  • Maria Pilar Gonçalves
  • Maria Helena Amaral
  • Teresa Cunha
  • Gustavo Dias
  • Bárbara Santos
  • Branca Teixeira
  • J das Neves
  • Cristina M R Rocha
  • Marta Vázquez da Silva
  • Maria H Amaral
  • Maria F Bahia
  • Jorge Brochado
  • Patrocínia Rocha
  • M F Bahia

Detail Information

Publications13

  1. ncbi request reprint Biodistribution and pharmacokinetics of dapivirine-loaded nanoparticles after vaginal delivery in mice
    José das Neves
    IINFACTS Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Instituto Superior de Ciencias da Saude Norte, CESPU, Rua Central de Gandra, 1317, 4585 116, Gandra, Portugal
    Pharm Res 31:1834-45. 2014
    ..To assess the potential of polymeric nanoparticles (NPs) to affect the genital distribution and local and systemic pharmacokinetics (PK) of the anti-HIV microbicide drug candidate dapivirine after vaginal delivery...
  2. ncbi request reprint Assessing the physical-chemical properties and stability of dapivirine-loaded polymeric nanoparticles
    José das Neves
    CICS Centro de Investigação em Ciências da Saúde, Department of Pharmaceutical Sciences, Instituto Superior de Ciencias da Saude Norte, CESPU, Rua Central de Gandra 1317, 4585 116 Gandra, Portugal Laboratory of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050 313 Porto, Portugal Electronic address
    Int J Pharm 456:307-14. 2013
    ..In any case, no degradation of dapivirine was apparent. Overall, PEO-PCL and SLS-PCL NPs presented suitable properties as nanocarriers for dapivirine. Conversely, CTAB-PCL NPs require additional strategies in order to increase stability...
  3. doi request reprint Interactions of microbicide nanoparticles with a simulated vaginal fluid
    José das Neves
    Laboratory of Pharmaceutical Technology, LTF CICF, Faculty of Pharmacy, University of Porto, Porto, Portugal
    Mol Pharm 9:3347-56. 2012
    ..Also, they further reinforce the importance in characterizing the interactions of nanosystems with mucus fluids or surrogates when considering mucosal drug delivery...
  4. doi request reprint Development and validation of a HPLC method for the assay of dapivirine in cell-based and tissue permeability experiments
    José das Neves
    Laboratory of Pharmaceutical Technology, LTF CICF, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050 313, Porto, Portugal
    J Chromatogr B Analyt Technol Biomed Life Sci 911:76-83. 2012
    ..Overall, the proposed method provides a simple, versatile and reliable way for studying the behavior of dapivirine in different biological matrices and assessing its potential as an anti-HIV microbicide drug...
  5. doi request reprint Polymeric nanoparticles affect the intracellular delivery, antiretroviral activity and cytotoxicity of the microbicide drug candidate dapivirine
    José das Neves
    Laboratory of Pharmaceutical Technology, LTF CICF Faculty of Pharmacy, University of Porto, Rua Anibal Cunha, 164, 4050 047, Porto, Portugal
    Pharm Res 29:1468-84. 2012
    ..To assess the intracellular delivery, antiretroviral activity and cytotoxicity of poly(ε-caprolactone) (PCL) nanoparticles containing the antiretroviral drug dapivirine...
  6. ncbi request reprint Gels as vaginal drug delivery systems
    J das Neves
    Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, Rua Anibal Cunha, 164, 4050 030 Porto, Portugal
    Int J Pharm 318:1-14. 2006
    ..Therefore, this paper discusses and summarizes current use and research of vaginal drug delivery systems based in gels...
  7. doi request reprint Development and validation of a rapid reversed-phase HPLC method for the determination of the non-nucleoside reverse transcriptase inhibitor dapivirine from polymeric nanoparticles
    José das Neves
    Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, Rua Anibal Cunha 164, 4050 047 Porto, Portugal
    J Pharm Biomed Anal 52:167-72. 2010
    ..08 and 0.24 microg/ml, respectively. The method was successfully used to determine the loading capacity and association efficiency of dapivirine in poly(lactic-co-glycolic acid)-based nanoparticles and its in vitro release...
  8. ncbi request reprint Rheological properties of vaginal hydrophilic polymer gels
    José das Neves
    Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, Porto, Portugal
    Curr Drug Deliv 6:83-92. 2009
    ..Rheological properties of tested gels appeared to be correlated with their therapeutic/usage purpose...
  9. ncbi request reprint Local treatment of vulvovaginal candidosis : general and practical considerations
    José das Neves
    Department of Microbiology, CEQUIMED, Faculty of Pharmacy, University of Porto, Porto, Portugal
    Drugs 68:1787-802. 2008
    ..g. pregnancy, menopause, drug hypersensitivity), women's preferences, and the availability, particularities and cost of antifungal formulations...
  10. doi request reprint Performance of an in vitro mucoadhesion testing method for vaginal semisolids: influence of different testing conditions and instrumental parameters
    José das Neves
    Department of Pharmaceutical Technology, Faculty of Pharmacy of the University of Porto, Porto, Portugal
    Eur J Pharm Biopharm 69:622-32. 2008
    ....
  11. doi request reprint Vaginal drug administration in the hospital setting
    José das Neves
    Department of Pharmaceutical Technology, University of Porto, Rua Anibal Cunha 164, Porto 4050 047, Portugal
    Am J Health Syst Pharm 65:254-9. 2008
  12. doi request reprint In vitro and ex vivo evaluation of polymeric nanoparticles for vaginal and rectal delivery of the anti-HIV drug dapivirine
    José das Neves
    Laboratory of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050 313 Porto, Portugal
    Mol Pharm 10:2793-807. 2013
    ..In particular, PEO-modified dapivirine-loaded PCL NPs may be advantageous in increasing drug residence at epithelial cell lines/mucosal tissues, which may potentially increase the efficacy of microbicide drugs. ..
  13. doi request reprint Mucoadhesive nanosystems for vaginal microbicide development: friend or foe?
    José das Neves
    Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, Porto, Portugal
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 3:389-99. 2011
    ..In this review, we discuss the principles of nanosystems' adhesion to the mucosal tissue and how this relates to the development of optimized microbicide formulations...