Prevalence of non-alcoholic fatty liver disease: population based studyDeepak Amarapurkar
Department of Gastroenterology, Jagjivanram Western Railway Hospital, Mumbai
Ann Hepatol 6:161-3. 2007
..Majority of data comes from hospital based studies including small number of patients. Therefore this study was planned to estimate the prevalence of NAFLD in general population...
Extrahepatic manifestations of viral hepatitisDeepak N Amarapurkar
Department of Gastroenterology, BYL Nair Hospital, TN Medical College, Mumbai, India
Ann Hepatol 1:192-5. 2002
..CONCLUSION: Prevalence of extrahepatic manifestations with viral hepatitis was found to be 6.4%. These manifestations recover completely with recovery from viral hepatitis...
Combination of Peginterferon alpha-2b (12 kDa) and Lamivudine in difficult-to-treat chronic hepatitis B- an Indian experienceDeepak N Amarapurkar
Head Gastroenterology Department, Bombay Hospital and Medical Research Center, Mumbai, India
Ann Hepatol 4:56-9. 2005
....
Antiviral therapy of decompensated cirrhosis due to hepatitis C viral infectionDeepak N Amarapurkar
Gastroenterology Department, Bombay Hospital and Medical Research Centre, Mumbai
Trop Gastroenterol 26:119-22. 2005
..CONCLUSION: Although there is high intolerance to the treatment, closely-monitored low dose escalating Interferon and/ or Ribavirin therapy achieves good results...
Primary mesenteric venous thrombosis: a study from western IndiaDeepak N Amarapurkar
Gastroenterology Department, Bombay Hospital and Medical Research Center, Mumbai, India
Indian J Gastroenterol 26:113-7. 2007
..The prevalence and clinical spectrum of mesenteric venous thrombosis (MVT) in India is largely unknown...
Intrinsic factor antibody negative atrophic gastritis; is it different from pernicious anaemia?D N Amarapurkar
Department of Gastroenterology and Hepatology, Bombay Hospital and Medical Research Centre, Mumbai, India
Trop Gastroenterol 31:266-70. 2010
..Parietal cell antibody (PCA) and intrinsic factor antibody (IFA) are characteristic of autoimmune gastritis, of which IFA is more specific. Patients who are IFA negative are considered under the category of chronic atrophic gastritis...
Diagnosis of Crohn's disease in India where tuberculosis is widely prevalentDeepak N Amarapurkar
Department of Gastroenterology, Bombay Hospital and Medical Research Centre, Mumbai 400025, India
World J Gastroenterol 14:741-6. 2008
..To define the parameters that positively predict diagnosis of Crohn's disease (CD) and differentiate it from gastrointestinal tuberculosis (GITB)...
An experience with covered transjugular intrahepatic portosystemic shunt for refractory ascites from western IndiaDeepak N Amarapurkar
Department of Gastroenterology, Bombay Hospital and Medical Research Centre, Mumbai, India
Ann Hepatol 5:103-8. 2006
..Use of covered TIPS has shown to improve shunt patency rate over uncovered TIPS. This retrospective analysis was performed on patients with RA to assess efficacy of TIPS, both covered and uncovered...
How common is non-alcoholic fatty liver disease in the Asia-Pacific region and are there local differences?Deepak N Amarapurkar
Bombay Hospital and Medical Research Center, Mumbai, India
J Gastroenterol Hepatol 22:788-93. 2007
..To date, however, data on the natural history and impact of NAFLD causing serious significant chronic liver disease are lacking and there is a need for prospective, cooperative studies...
Changing spectrum of Budd-Chiari syndrome in India with special reference to non-surgical treatmentDeepak N Amarapurkar
Department of Gastroenterology, Bombay Hospital and Medical Research Centre, D 401 Ameya Society, New Prabhadevi Road, Mumbai 400025, India
World J Gastroenterol 14:278-85. 2008
..To evaluate patterns of obstruction, etiological spectrum and non-surgical treatment in patients with Budd-Chiari syndrome in India...
Telbivudine: a new treatment for chronic hepatitis BDeepak N Amarapurkar
Department of Gastroenterology and Hepatology, Bombay Hospital and Medical Research Centre, Mumbai 400025, India
World J Gastroenterol 13:6150-5. 2007
..Telbivudine is one of the most potent antiviral agents for chronic hepatitis B virus and was approved by the FDA in late 2006...
Role of liver biopsy in management of chronic hepatitis B and chronic hepatitis CDeepak Amarapurkar
Bombay Hospital and Medical Research Centre, Mumbai
Trop Gastroenterol 28:67-8. 2007
Genotype III - HCV infectionD N Amarapurkar
Department of Gastroenterology, Bombay Hospital and Medical Research Centre, Mumbai, India
Trop Gastroenterol 28:58-63. 2007
Do different hepatitis C virus genotypes behave differently?Deepak N Amarapurkar
Department of Gastroenterology, Bombay Hospital and Medical Research Centre, Mumbai
Trop Gastroenterol 28:99-104. 2007
..The natural history of hepatitis C genotype III infection, the predominant form in India, is not wholly understood. This study attempted to compare the natural history of diseases due to genotypes III and I...
Impact of diabetes mellitus on outcome of HCCDeepak N Amarapurkar
Ameya RBI Employees, Co Op Housing Society, Prabhadevi, Mumbai
Ann Hepatol 7:148-51. 2008
..We planned a prospective analysis to identify impact of DM in Indian patients with HCC...
A retrospective clinico-pathological analysis of neuroendocrine tumors of the gastrointestinal tractD N Amarapurkar
Department of Gastroenterology and Hepatology, Bombay Hospital Medical Research Centre, Mumbai
Trop Gastroenterol 31:101-4. 2010
..However, there has been change in pattern of gastrointestinal neuroendocrine tumors over last few years. There is limited data available on epidemiology and patterns of these tumors in India...
Gastrointestinal luminal tuberculosis: establishing the diagnosisNikhil Patel
Department of Gastroenterology, Jagjivanram Hospital, Mumbai, India
J Gastroenterol Hepatol 19:1240-6. 2004
..To study the profile of gastrointestinal luminal tuberculosis (GITB) patients who have been treated on a confirmed and a presumptive diagnosis...
Non-alcoholic steatohepatitis in type 2 diabetes mellitusParijat Gupte
Gastroenterology Center, Jagjivanram Hospital, Mumbai Central, Mumbai, Maharashtra, India
J Gastroenterol Hepatol 19:854-8. 2004
..CONCLUSION: We conclude that the prevalence of NASH is high in type 2 DM patients and liver biopsy is the only investigation to differentiate between non-alcoholic fatty liver and steatohepatitis...
Monitoring and management of antituberculosis drug induced hepatotoxicitySubhash Agal
Department of Gastroenterology, Jagjivanram Hospital, Mumbai, India
J Gastroenterol Hepatol 20:1745-52. 2005
..CONCLUSIONS: Periodic laboratory monitoring is important in detecting hepatotoxicity at an early stage, thereby preventing mortality. Sequential reintroduction is often successful...
Application of surveillance programs for hepatocellular carcinoma in the Asia-Pacific RegionDeepak Amarapurkar
Bombay Hospital and Medical Research Centre, Mumbai, India
J Gastroenterol Hepatol 24:955-61. 2009
..In conclusion, HCC surveillance could be effective at reducing disease-specific mortality with acceptable cost-effectiveness among selected patient groups, provided it is a well-organized program...
Consensus on extra-hepatic portal vein obstructionShiv Kumar Sarin
Department of Gastroenterology, G B Pant Hospital, Affiliated to University of Delhi, New Delhi, India
Liver Int 26:512-9. 2006
..This article summarizes all the consensus statements approved by the APASL on various aspects of EHPVO...
Increased prevalence of type II diabetes mellitus in hepatitis C virus infection in western IndiaDeepak N Amarapurkar
Department of Gastroenterology, Bombay Hospital and Medical Research Centre, Mumbai, India
Trop Gastroenterol 29:148-52. 2008
..Type II diabetes mellitus (DM) has been shown as more common in patients with hepatitis C virus infection (HCV). Similar data from India is not available...
Primary biliary cirrhosis and autoimmune hepatitis switch over: report of 2 casesNikhil Patel
BYL Nair Charitable Hospital, Mumbai, India
Trop Gastroenterol 26:136-8. 2005
..We report 2 cases of primary biliary cirrhosis (PBC) who with time, crossed over to autoimmune hepatitis (AIH). Recognition of such switch over from PBC to AIH is important for appropriate change in management of the patients...
Biliary ascariasisDeepak Amarapurkar
Department of Gastroenterology, Bombay Hospital and Medical Research Centre, Mumbai, India
J Hepatol 40:558. 2004
Helicobacter pylori eradication: efficacy of conventional therapy in IndiaDeepak Amarapurkar
Bombay Hospital and Research Centre, Mumbai, India
Trop Doct 34:101-2. 2004
Monotherapy with peginterferon alpha-2b {12 kDa} for chronic hepatitis C infection in patients undergoing haemodialysisDeepak N Amarapurkar
Department of Gastroenterology, Bombay Hospital and Medical Research Centre, Mumbai, India
Trop Gastroenterol 28:16-8. 2007
..Ribavirin is contraindicated in patients with chronic renal failure (CRF). Conventional Interferon monotherapy is effective in around 30% of such patients. There is scanty data on the use of Peginterferon monotherapy in them...
Spectrum of autoimmune liver diseases in western IndiaDeepak N Amarapurkar
Gastroenterology Department, Bombay Hospital and Medical Research Center, Mumbai, India
J Gastroenterol Hepatol 22:2112-7. 2007
..The prevalence and spectrum of autoimmune liver diseases (AILDs) in India are rarely reported in comparison to the West...
Prevalence of metabolic syndrome in non-diabetic and non-cirrhotic patients with non-alcoholic steatohepatitisDeepak N Amarapurkar
Gastroenterology Department, Bombay Hospital and Medical Research Center, Mumbai
Trop Gastroenterol 25:125-9. 2004
..Also, all patients with metabolic syndrome should undergo liver function tests and, in the presence of abnormal transaminases, a liver biopsy to define NASH...
Clinical spectrum and natural history of non-alcoholic steatohepatitis with normal alanine aminotransferase valuesDeepak N Amarapurkar
Department of Gastroenterology, Bombay Hospital and Medical Research Center, Mumbai
Trop Gastroenterol 25:130-4. 2004
..In patients with diabetes and hepatomegaly in the absence of other obvious liver diseases, even normal ALT may not rule out advanced liver disease, and liver biopsy may be necessary to identify the severity of liver disease...
Hepatobiliary tuberculosis in western IndiaDeepak N Amarapurkar
Department of Gastroenterology, Bombay Hospital and Medical Research Centre, India
Indian J Pathol Microbiol 51:175-81. 2008
..HBTB forms an important subgroup in TB cases. It requires a combination of imaging, histological and microbiological procedures to define the diagnosis. HBTB responds well to treatment...
Randomised, double-blind, comparative study to evaluate the efficacy and safety of ganaton (itopride hydrochloride) and mosapride citrate in the management of functional dyspepsiaDeepak N Amarapurkar
Bombay Hospital and Medical Research Centre, Mumbai
J Indian Med Assoc 102:735-7, 760. 2004
..7%) (p < 0.05) and poor in 0 (0%) versus 6 (20%) patients respectively. It may be concluded that ganaton (itopride hydrochloride) is superior in efficacy and safety over mosapride citrate in the management of functional dyspepsia...
Primary gastric tuberculosis--report of 5 casesDeepak N Amarapurkar
Department of Gastroenterology, Bombay Hospital and Medical Research Centre, India
BMC Gastroenterol 3:6. 2003
..Gastric tuberculosis is rare, and usually associated with pulmonary tuberculosis or an immunodeficient state. Here, we report five cases of gastric tuberculosis in immunocompetent patients without evidence of pulmonary involvement...
Human leukocyte antigen allele associations in type-1 autoimmune hepatitis patients from western IndiaUmapathy Shankarkumar
HLA Department, Institute of Immunohaematology ICMR, KEM Hospital, Parel, Mumbai 400 012, Maharashtra, India
J Gastroenterol Hepatol 20:193-7. 2005
..The immunogenetic basis of autoimmune diseases has become more and more evident. We have analyzed the human leukocyte antigen (HLA) associations with type-1 autoimmune hepatitis (AIH) among patients from western India...
Angiogenesis in chronic liver diseaseAnjali D Amarapurkar
Department of Pathology, BYL Nair Charitable Hospital and TN Medical College, India
Ann Hepatol 6:170-3. 2007
..Interfering with angiogenesis may be a potential target to avoid progression of liver disease. Hence we planned to evaluate the CD34 and vascular endothelial growth factor (VEGF), the markers for angiogenesis in chronic liver disease...