Mark D Alter

Summary

Publications

  1. doi request reprint Is there a genomic tone? Implications for understanding development, adaptation and treatment
    Mark D Alter
    Department of Psychiatry, Divisions of Child and Adolescent Psychiatry, and Division of Integrative Neuroscience, Columbia University, New York, N Y 10032, USA
    Dev Neurosci 31:351-7. 2009
  2. pmc Autism and increased paternal age related changes in global levels of gene expression regulation
    Mark D Alter
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e16715. 2011
  3. pmc Studying gene expression system regulation at the program level
    Mark D Alter
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 8:e61324. 2013
  4. pmc Variation in the large-scale organization of gene expression levels in the hippocampus relates to stable epigenetic variability in behavior
    Mark D Alter
    Department of Psychiatry, Columbia University, New York, New York, United States of America
    PLoS ONE 3:e3344. 2008
  5. doi request reprint Paternal transmission of complex phenotypes in inbred mice
    Mark D Alter
    Columbia University, New York, New York, USA
    Biol Psychiatry 66:1061-6. 2009
  6. pmc Measuring the maturity of the fast-spiking interneuron transcriptional program in autism, schizophrenia, and bipolar disorder
    Michael J Gandal
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e41215. 2012
  7. doi request reprint Putting a KAP on transcription and stress
    Mark D Alter
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Neuron 60:733-5. 2008

Collaborators

Detail Information

Publications7

  1. doi request reprint Is there a genomic tone? Implications for understanding development, adaptation and treatment
    Mark D Alter
    Department of Psychiatry, Divisions of Child and Adolescent Psychiatry, and Division of Integrative Neuroscience, Columbia University, New York, N Y 10032, USA
    Dev Neurosci 31:351-7. 2009
    ..We suggest that genomic tone may be related to the plasticity of the gene expression system and may be an important target for developmental and therapeutic interventions...
  2. pmc Autism and increased paternal age related changes in global levels of gene expression regulation
    Mark D Alter
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e16715. 2011
    ..Global regulation of transcription, thus, represents a possible point of convergence for multiple etiologies of autism and other neurodevelopmental disorders...
  3. pmc Studying gene expression system regulation at the program level
    Mark D Alter
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 8:e61324. 2013
    ....
  4. pmc Variation in the large-scale organization of gene expression levels in the hippocampus relates to stable epigenetic variability in behavior
    Mark D Alter
    Department of Psychiatry, Columbia University, New York, New York, United States of America
    PLoS ONE 3:e3344. 2008
    ..We challenge this idea by exploring the large-scale organizational patterns of gene expression in an epigenetic model of behavioral variability...
  5. doi request reprint Paternal transmission of complex phenotypes in inbred mice
    Mark D Alter
    Columbia University, New York, New York, USA
    Biol Psychiatry 66:1061-6. 2009
    ..Although maternal effects have been reported in biparental and uniparental strains, there have been no investigations of paternal effects in non-biparental strains in which offspring are reared exclusively by mothers...
  6. pmc Measuring the maturity of the fast-spiking interneuron transcriptional program in autism, schizophrenia, and bipolar disorder
    Michael J Gandal
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e41215. 2012
    ..Although these results suggest that FS cells may be immature in neuropsychiatric disease, this possibility had not previously been formally assessed...
  7. doi request reprint Putting a KAP on transcription and stress
    Mark D Alter
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Neuron 60:733-5. 2008
    ..In this issue of Neuron, Jakobsson et al. find that disruption in neurons of KAP1, a key component of transcriptional repressor complexes in the brain, results in increased anxiety-like behavior and sensitivity to stress...