John M Aletta

Summary

Publications

  1. doi request reprint Protein arginine methylation in health and disease
    John M Aletta
    CH3 BioSystems, LLC, Amherst, New York 14228, USA
    Biotechnol Annu Rev 14:203-24. 2008
  2. pmc Accurate localization and relative quantification of arginine methylation using nanoflow liquid chromatography coupled to electron transfer dissociation and orbitrap mass spectrometry
    Hao Wang
    Department of Pharmaceutical Sciences, University at Buffalo, State University of New York, Amherst, New York, USA
    J Am Soc Mass Spectrom 20:507-19. 2009
  3. ncbi request reprint Nerve growth factor-mediated increases in protein methylation occur predominantly at type I arginine methylation sites and involve protein arginine methyltransferase 1
    Thomas R Cimato
    Department of Pharmacology and Toxicology, University at Buffalo School of Medicine and Biomedical Sciences, State University of New York, 3435 Main Street, Buffalo, NY 14214 3000, USA
    J Neurosci Res 67:435-42. 2002
  4. ncbi request reprint NGF promotes copper accumulation required for optimum neurite outgrowth and protein methylation
    Barbara Birkaya
    Department of Pharmacology and Toxicology, Center for Neuroscience, University at Buffalo School of Medicine and Biomedical Sciences, State University of New York, 3435 Main Street, Buffalo, New York 14214 3000, USA
    J Neurobiol 63:49-61. 2005
  5. ncbi request reprint Methylation regulates the intracellular protein-protein and protein-RNA interactions of FMRP
    Natalia Dolzhanskaya
    Biochemical Molecular Neurobiology Laboratory, Department of Molecular Biology, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA
    J Cell Sci 119:1933-46. 2006
  6. pmc Generation of polyclonal antiserum for the detection of methylarginine proteins
    Peng Duan
    Center for Neuroscience, Department of Pharmacology and Toxicology, University at Buffalo School of Medicine and Biomedical Sciences 102 Farber Hall 3435 Main Street Buffalo, New York 14214 3000, USA
    J Immunol Methods 320:132-42. 2007

Collaborators

  • R B Denman
  • Harvey Herschman
  • Barbara Birkaya
  • Hao Wang
  • Peng Duan
  • Natalia Dolzhanskaya
  • Sandor Pongor
  • Ye Xu
  • Corrado Guarnaccia
  • Thomas R Cimato
  • Jun Qu
  • Jin Cao
  • Robert M Straubinger
  • Haoying Yu
  • Xiaotao Duan
  • Laurie K Read
  • Michel Pelletier
  • Jason Myers
  • George Merz
  • Jie Tang

Detail Information

Publications6

  1. doi request reprint Protein arginine methylation in health and disease
    John M Aletta
    CH3 BioSystems, LLC, Amherst, New York 14228, USA
    Biotechnol Annu Rev 14:203-24. 2008
    ....
  2. pmc Accurate localization and relative quantification of arginine methylation using nanoflow liquid chromatography coupled to electron transfer dissociation and orbitrap mass spectrometry
    Hao Wang
    Department of Pharmaceutical Sciences, University at Buffalo, State University of New York, Amherst, New York, USA
    J Am Soc Mass Spectrom 20:507-19. 2009
    ..This approach and the results may advance understanding of the actions of PRMTs and the functional significance of Arg methylation patterns...
  3. ncbi request reprint Nerve growth factor-mediated increases in protein methylation occur predominantly at type I arginine methylation sites and involve protein arginine methyltransferase 1
    Thomas R Cimato
    Department of Pharmacology and Toxicology, University at Buffalo School of Medicine and Biomedical Sciences, State University of New York, 3435 Main Street, Buffalo, NY 14214 3000, USA
    J Neurosci Res 67:435-42. 2002
    ..Finally, immunoprecipitation of PRMT1 from PC12 cells provides the first demonstration of an NGF-activated methyltransferase and implicates PRMT1 in NGF signal transduction...
  4. ncbi request reprint NGF promotes copper accumulation required for optimum neurite outgrowth and protein methylation
    Barbara Birkaya
    Department of Pharmacology and Toxicology, Center for Neuroscience, University at Buffalo School of Medicine and Biomedical Sciences, State University of New York, 3435 Main Street, Buffalo, New York 14214 3000, USA
    J Neurobiol 63:49-61. 2005
    ..These data comprise the first biochemical and cellular evidence to address the mechanism of copper involvement in neuronal differentiation...
  5. ncbi request reprint Methylation regulates the intracellular protein-protein and protein-RNA interactions of FMRP
    Natalia Dolzhanskaya
    Biochemical Molecular Neurobiology Laboratory, Department of Molecular Biology, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA
    J Cell Sci 119:1933-46. 2006
    ..These data suggest a vital role for methylation in normal FMRP functioning...
  6. pmc Generation of polyclonal antiserum for the detection of methylarginine proteins
    Peng Duan
    Center for Neuroscience, Department of Pharmacology and Toxicology, University at Buffalo School of Medicine and Biomedical Sciences 102 Farber Hall 3435 Main Street Buffalo, New York 14214 3000, USA
    J Immunol Methods 320:132-42. 2007
    ....