T Alarcon

Summary

Publications

  1. ncbi request reprint Further experience of nonagenarians with hip fractures
    T Alarcon
    Geriatric Assessment Team, Hospital Universitario La Paz, Paseo de la Castellana 261, 28046, Madrid, Spain
    Injury 32:555-8. 2001
  2. ncbi request reprint Antibiotic resistance problems with Helicobacter pylori
    T Alarcon
    Department of Clinical Microbiology, Hospital Universitario de la Princesa, Madrid, Spain
    Int J Antimicrob Agents 12:19-26. 1999
  3. ncbi request reprint [Susceptibility of 36 Helicobacter pylori clinical isolates to four first-line antibiotics and virulence factors]
    J Díaz-Regañón
    Servicio de Microbiologia, Hospital Universitario de la Princesa, Madrid, Spain
    Rev Esp Quimioter 19:34-8. 2006
  4. ncbi request reprint [Detection of resistance to clarithromycin in clinical isolates of Helicobacter pylori from children and adults]
    A E Vega
    Servicio de Microbiologia, Hospital Universitario de la Princesa, Madrid, Espana
    Rev Esp Quimioter 16:53-7. 2003
  5. ncbi request reprint A 9 year study of clarithromycin and metronidazole resistance in Helicobacter pylori from Spanish children
    M Lopez-Brea
    Department of Microbiology, Hospital Universitario de la Princesa, Diego de Leon 62, 28006 Madrid, Spain
    J Antimicrob Chemother 48:295-7. 2001
  6. ncbi request reprint [The Helicobacter pylori adhesion gene: relation with the origin of the isolates and associated disease]
    D Domingo
    Servicio de Microbiologia, Hospital Universitario de la Princesa, Madrid
    Enferm Infecc Microbiol Clin 17:342-6. 1999
  7. pmc PCR using 3'-mismatched primers to detect A2142C mutation in 23S rRNA conferring resistance to clarithromycin in Helicobacter pylori clinical isolates
    T Alarcon
    Department of Microbiology, Hospital Universitario de la Princesa, Madrid, Spain
    J Clin Microbiol 38:923-5. 2000
  8. ncbi request reprint Study of the combination of ranitidine bismuth citrate and metronidazole against metronidazole-resistant Helicobacter pylori clinical isolates
    M Lopez-Brea
    Department of Microbiology, Hospital Universitario de la Princesa, Madrid, Spain
    J Antimicrob Chemother 42:309-14. 1998
  9. ncbi request reprint [Susceptibility of Campylobacter jejuni clinical isolates from children to eight antibiotics]
    J A García-Campos
    Servicio de Microbiologia, Hospital Universitario de la Princesa, Madrid, Spain
    Rev Esp Quimioter 16:216-20. 2003
  10. ncbi request reprint A new hierarchical classification for prognosis of hip fracture after 2 years' follow-up
    T Alarcon
    Servicio de Geriatria, Hospital Universitario La Paz, Madrid, Spain
    J Nutr Health Aging 15:919-23. 2011

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Further experience of nonagenarians with hip fractures
    T Alarcon
    Geriatric Assessment Team, Hospital Universitario La Paz, Paseo de la Castellana 261, 28046, Madrid, Spain
    Injury 32:555-8. 2001
    ..These nonagenarian patients with hip fractures show low perioperative mortality, frequently return to their previous accommodation and present a limited recovery of walking ability...
  2. ncbi request reprint Antibiotic resistance problems with Helicobacter pylori
    T Alarcon
    Department of Clinical Microbiology, Hospital Universitario de la Princesa, Madrid, Spain
    Int J Antimicrob Agents 12:19-26. 1999
    ..Infection with metronidazole- or clarithromycin-resistant H. pylori strains is correlated with treatment failure when using regimens including these antibiotics...
  3. ncbi request reprint [Susceptibility of 36 Helicobacter pylori clinical isolates to four first-line antibiotics and virulence factors]
    J Díaz-Regañón
    Servicio de Microbiologia, Hospital Universitario de la Princesa, Madrid, Spain
    Rev Esp Quimioter 19:34-8. 2006
    ..The cagA+ strains were detected in expected quantities, while the s1 allele of the vacA gene was detected in lower quantities...
  4. ncbi request reprint [Detection of resistance to clarithromycin in clinical isolates of Helicobacter pylori from children and adults]
    A E Vega
    Servicio de Microbiologia, Hospital Universitario de la Princesa, Madrid, Espana
    Rev Esp Quimioter 16:53-7. 2003
    ..66% vs. 5.55%; p<0.05). In children, a higher MIC (2-64 mg/l) was observed when the A-G mutation was detected at position 2143. However, in adult patients higher MICs were observed when the A-G mutation was detected at position 2142...
  5. ncbi request reprint A 9 year study of clarithromycin and metronidazole resistance in Helicobacter pylori from Spanish children
    M Lopez-Brea
    Department of Microbiology, Hospital Universitario de la Princesa, Diego de Leon 62, 28006 Madrid, Spain
    J Antimicrob Chemother 48:295-7. 2001
    ..14% (IC95 1.49-19.48) in 1991-1993, 20.25% (IC95 12.04-30.79) in 1994-1996 and 43.90% (IC95 32.95-55.30) in 1997-1999 (P < 0.01). Amoxycillin resistance was not found (all strains showed MICs < 2 mg/L)...
  6. ncbi request reprint [The Helicobacter pylori adhesion gene: relation with the origin of the isolates and associated disease]
    D Domingo
    Servicio de Microbiologia, Hospital Universitario de la Princesa, Madrid
    Enferm Infecc Microbiol Clin 17:342-6. 1999
    ..The adhesion gene (hpaA) of Helicobacter pylori isolates from different Spanish regions was studied by PCR-RFLP in order to group the strains according to the origin of the strains and to relate it with ulcer or gastritis production...
  7. pmc PCR using 3'-mismatched primers to detect A2142C mutation in 23S rRNA conferring resistance to clarithromycin in Helicobacter pylori clinical isolates
    T Alarcon
    Department of Microbiology, Hospital Universitario de la Princesa, Madrid, Spain
    J Clin Microbiol 38:923-5. 2000
    ..A 700-bp amplified fragment was obtained by the mismatched PCR only in strains without an A2142G or A2143G mutation, indicating that those strains had the A2142C mutation...
  8. ncbi request reprint Study of the combination of ranitidine bismuth citrate and metronidazole against metronidazole-resistant Helicobacter pylori clinical isolates
    M Lopez-Brea
    Department of Microbiology, Hospital Universitario de la Princesa, Madrid, Spain
    J Antimicrob Chemother 42:309-14. 1998
    ..In the last strain, a 2log10 decrease in the initial number was observed with RBC alone or combined with metronidazole...
  9. ncbi request reprint [Susceptibility of Campylobacter jejuni clinical isolates from children to eight antibiotics]
    J A García-Campos
    Servicio de Microbiologia, Hospital Universitario de la Princesa, Madrid, Spain
    Rev Esp Quimioter 16:216-20. 2003
    ..Considered the antibiotics of choice for the treatment of infections caused by this microorganism, macrolides showed excellent activity with MIC(90)=0.5 mg/l for azithromycin and MIC(90)=0.5 mg/l for erythromycin...
  10. ncbi request reprint A new hierarchical classification for prognosis of hip fracture after 2 years' follow-up
    T Alarcon
    Servicio de Geriatria, Hospital Universitario La Paz, Madrid, Spain
    J Nutr Health Aging 15:919-23. 2011
    ..To examine the prognostic value of different profiles of hip fracture patients for recovery of pre-fracture functional level and for post-fracture mortality...
  11. ncbi request reprint Clarithromycin resistance stability in Helicobacter pylori: influence of the MIC and type of mutation in the 23S rRNA
    T Alarcon
    Department of Microbiology, Hospital Universitario de la Princesa, Diego de Leon 62, 28006 Madrid, Spain
    J Antimicrob Chemother 46:613-6. 2000
    ..pylori NCTC 11638 and TIGR 26695. A change in the MIC was observed only when NCTC11638 was exposed to 0.5 x MIC of erythromycin for 20 days...
  12. pmc Prevalence of CagA and VacA antibodies in children with Helicobacter pylori-associated peptic ulcer compared to prevalence in pediatric patients with active or nonactive chronic gastritis
    T Alarcon
    Department of Microbiology, Hospital Universitario de la Princesa, Madrid, Spain
    Clin Diagn Lab Immunol 7:842-4. 2000
    ..2 and 39.2% in non-ACG patients. Higher seroprevalence to CagA+VacA and to CagA+VacA+35-kDa antigen was found among PU patients. However, a low level of sensitivity and specificity was found for indirect detection of PU patients...
  13. ncbi request reprint In vitro activity of clinafloxacin against fluoroquinolone resistant Spanish clinical isolates
    M Lopez-Brea
    Department of Microbiology, Hospital Universitario de la Princesa, Madrid, Spain
    Int J Antimicrob Agents 12:33-9. 1999
    ..aureus and 40% for Enterococcus spp. Clinafloxacin was active against 58.6% of the ciprofloxacin-resistant clinical isolates tested. It was particularly active against S. aureus strains resistant to both ciprofloxacin and methicillin...
  14. ncbi request reprint [High percentage of clarithromycin and metronidazole resistance in Helicobacter pylori clinical isolates obtained from Spanish children]
    S Agudo
    Hospital de la Princesa, Madrid, Spain
    Rev Esp Quimioter 22:88-92. 2009
    ..To determine the primary and secondary resistance to several antimicrobial agents in Spanish Helicobacter pylori clinical isolates obtained from paediatric patients from January 2002 to June 2006...
  15. ncbi request reprint [Susceptibility pattern of Acinetobacter baumannii clinical isolates in Madrid vs. Hong Kong]
    E García-Peñuela
    Departamento de Microbiologia, Hospital Universitario de la Princesa, Madrid, Spain
    Rev Esp Quimioter 19:45-50. 2006
    ..To ofloxacin, 90% of Hong Kong isolates were susceptible while 93% of Madrid isolates were resistant. Geographically remote populations (such as Madrid and Hong Kong) showed important differences according to the susceptibility patterns...
  16. ncbi request reprint High-level mupirocin resistance among Spanish methicillin-resistant Staphylococcus aureus
    T Alarcon
    Department of Microbiology, Hospital Universitario de la Princesa, Madrid, Spain
    Eur J Clin Microbiol Infect Dis 17:877-9. 1998
    ..The use of this valuable topical antibiotic, especially in long-term-care facilities, should be monitored to avoid dissemination of resistance...
  17. ncbi request reprint Rapid detection of clarithromycin resistant Helicobacter pylori strains in Spanish patients by polymerase chain reaction-restriction fragment length polymorphism
    S Agudo
    Hospital de la Princesa, Madrid, Spain
    Rev Esp Quimioter 24:32-6. 2011
    ..pylori clarithromycin-resistance strains in Spain and evaluate a novel PCR-RFLP method for detection of the most frequent point mutation in our population...
  18. ncbi request reprint [In vitro activity of furazolidone and nitrofurantoin in Helicobacter pylori clinical isolates and study of mutation rate]
    T Alarcon
    Servicio de Microbiologia, Hospital Universitario de la Princesa, Madrid
    Rev Esp Quimioter 18:313-8. 2005
    ..pylori clinical isolates included herein, supporting the usefulness of furazolidone as second-line antimicrobial after treatment failure or as first-line therapy in populations with low economical resources...
  19. ncbi request reprint Detection of decreased susceptibility to fluoroquinolones in Salmonella spp. by five different methods including real-time polymerase chain reaction (PCR)
    E Aznar
    Servicio de Microbiologia y Parasitologia, Hospital Universitario La Princesa, Madrid, C Diego de Leon, No 62, 28006 Madrid, Spain
    Int J Antimicrob Agents 30:67-71. 2007
    ..Nalidixic acid disk diffusion was confirmed as a good screening method. Tm analysis is a rapid and accurate method for detecting decreased susceptibility to fluoroquinolones due to gyrA mutations in Salmonella spp...
  20. doi request reprint Activities of daily living after hip fracture: profile and rate of recovery during 2 years of follow-up
    T Alarcon
    Servicio de Geriatria, Hospital Universitario La Paz, IdiPAZ, Servicio Madrileño de Salud, Paseo Castellana 261, 28046 Madrid, Spain
    Osteoporos Int 22:1609-13. 2011
    ..In this study 509 hip fracture patients were followed-up during 24 months measuring their recuperation in activities of daily living. The different activities measured had both different profile and probability of recovery...
  21. ncbi request reprint In vitro activity of CA(1-8)M(1-18), a synthetic cecropin A-melittin hybrid peptide, against multiresistant Acinetobacter baumannii strains
    T Alarcon
    Servicio de Microbiologia, Hospital Universitario de la Princesa, Madrid, Spain
    Rev Esp Quimioter 14:184-90. 2001
    ..baumannii strains tested irrespective of the resistance to classical antibiotics, and could be a future candidate for multiresistant A. baumannii infections, although further cytotoxicity and pharmacological studies will be needed...
  22. ncbi request reprint [In vitro activity of clarithromycin and metronidazole against Helicobacter pylori in different incubation atmospheres]
    T Alarcon
    Servicio de Microbiologia, Hospital Universitario de la Princesa, Madrid, Spain
    Rev Esp Quimioter 15:341-5. 2002
    ..7% of strains the MICs showed < or = 2 dilutions of difference. No great discrepancies were found for either metronidazole or clarithromycin using the two methods...