Laila AL-Ayadhi


Affiliation: Autism Research & Treatment Center
Location: Riyadh, Saudi Arabia
Biomarkers research in ASD
studding the effectiveness of some proposed intervention in ASD


  1. AlAyadhi L, Hashmi J, Iqbal M, Albalawi A, Samman M, Elamin N, et al. High-resolution SNP genotyping platform identified recurrent and novel CNVs in autism multiplex families. Neuroscience. 2016;339:561-570 pubmed publisher
    ..These results verify the diagnostic relevance of genome-wide small common and rare CNVs and provide further evidence of the high diagnostic yield of microarray for genetic testing in children with ASD. ..
  2. Al Ayadhi L. Relationship between Sonic hedgehog protein, brain-derived neurotrophic factor and oxidative stress in autism spectrum disorders. Neurochem Res. 2012;37:394-400 pubmed publisher
    ..Our findings are the first to report a correlation between SHH, BDNF and OFR in autistic children, suggesting a pathological role of oxidative stress and SHH in autism spectrum disorders. ..
  3. Al Askar M, Bhat R, Selim M, Al Ayadhi L, El Ansary A. Postnatal treatment using curcumin supplements to amend the damage in VPA-induced rodent models of autism. BMC Complement Altern Med. 2017;17:259 pubmed publisher
    ..Curcumin plays a significant therapeutic role in attenuating brain damage that has been induced by prenatal VPA exposure in rats; however, its therapeutic role as a dietary supplement still must be certified for use in humans. ..

Detail Information