Fatty liver is a good indicator of subclinical atherosclerosis risk in obese children and adolescents regardless of liver enzyme elevationLeyla Akin
Department of Pediatric Endocrinology, Faculty of Medicine, Erciyes University, Kayseri, Turkey
Acta Paediatr 102:e107-13. 2013
..Additionally, we wished to investigate the relationship between fatty liver and elevated liver enzymes...
A case of diabetes mellitus associated with Rett syndromeLeyla Akin
Department of Pediatrics, Faculty of Medicine, Erciyes University, Kayseri, Turkey
J Pediatr Endocrinol Metab 25:197-8. 2012
..In this work, we report the case of a 9-year-old girl with RS who developed DM at the age of 6. To our knowledge, our patient is the third case reported to date of DM associated with Rett syndrome...
- Primary adrenal failure due to viral infection in an infant
Leyla Akin
Department of Pediatric Endocrinology, Faculty of Medicine, Erciyes University, Kayseri, Turkey
Eur J Pediatr 169:887-9. 2010
..She was treated successfully with steroid replacement and ganciclovir. Early diagnosis and treatment is lifesaving in these patients...
- The association of serum sialic acid with carotid intima-media thickness and anthropometric and metabolic parameters in obese children and adolescents
Leyla Akin
Department of Pediatric Endocrinology, Faculty of Medicine, Erciyes University, Kayseri, Turkey
Ann Nutr Metab 59:139-44. 2011
..Sialic acid (SA) has been shown to be a strong predictor of cardiovascular mortality in adults. No study in children regarding the association of SA with cardiovascular risks exists in the literature...
Does early treatment prevent deafness in thiamine-responsive megaloblastic anaemia syndrome?Leyla Akin
Erciyes University, Faculty of Medicine Department of Pediatric Endocrinology, Kayseri, Turkey
J Clin Res Pediatr Endocrinol 3:36-9. 2011
..It would be premature to draw general conclusions from one case, but we believe that further patient-based observations can shed light on the pathophysiology of this rare syndrome as well as prediction of its prognosis...
- Familial glucocorticoid deficiency type 2: a case report
Leyla Akin
Erciyes University, Faculty of Medicine, Department of Pediatric Endocrinology, Kayseri, Turkey
J Clin Res Pediatr Endocrinol 2:122-5. 2010
..We found a homozygous deletion (c. 106+1delG) in intron 3 of MRAP gene. To our knowledge, this is the first Turkish patient reported with FGD type 2 due to a known MRAP mutation...
- Vitamin D deficiency rickets mimicking pseudohypoparathyroidism
Leyla Akin
Department of Pediatrics, Erciyes University Faculty of Medicine, Kayseri, Turkey
J Clin Res Pediatr Endocrinol 2:173-5. 2010
..The initial findings of hypocalcemia, hyperphosphatemia and normal tubular reabsorption of phosphate, mimicking PHP 2, responded well to vitamin D and oral Ca treatment with normalization of serum Ca, phosphorus (P), ALP and PTH levels...
- Hook effect: a pitfall leading to misdiagnosis of hypoaldosteronism in an infant with pseudohypoaldosteronism
Leyla Akin
Department of Pediatric Endocrinology, Faculty of Medicine, Erciyes University, Kayseri, Turkey
Horm Res Paediatr 74:72-5. 2010
..A repeated test after dilution of the serum revealed a very high level of aldosterone (6,490 pg/ml), confirming the diagnosis of PHA in this case...
- Melnick-Needles syndrome associated with growth hormone deficiency: a case report
Leyla Akin
Department of Pediatric Endocrinology, Erciyes University, Faculty of Medicine, Kayseri, Turkey
J Clin Res Pediatr Endocrinol 1:248-51. 2009
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- The absence of insulin resistance in metabolic syndrome definition leads to underdiagnosing of metabolic risk in obese patients
Selim Kurtoglu
Department of Pediatric Endocrinology, Faculty of Medicine, Erciyes University, Kayseri, Turkey
Eur J Pediatr 171:1331-7. 2012
..In conclusion, IR was prominent in obese patients with and without MS. IDF definition of MS fails to discover individuals with IR, unless it is specifically investigated...
- A novel mutation in the MC2R gene causing familial glucocorticoid deficiency type 1
Mustafa Ali Akin
Department of Neonatology, Faculty of Medicine, Erciyes University, Kayseri, Turkey
Neonatology 100:277-81. 2011
..Genetic analysis revealed a novel homozygous melanocortin 2 receptor mutation p.Leu225Arg in the patient. The healthy parents were heterozygous for the mutation...
- Follow-up during early infancy of newborns diagnosed with subcutaneous fat necrosis
Mustafa Ali Akin
Erciyes University, Faculty of Medicine, Department of Pediatrics, Division of Neonatology, Kayseri, Turkey
J Clin Res Pediatr Endocrinol 3:216-8. 2011
..We would like to draw attention to the need to monitor serum calcium levels in these infants and to refrain from initiating vitamin D prophylaxis in the first months of life...
- Post-operative subcutaneous fat necrosis in a newborn: a case report
Mustafa Ali Akin
Department of Neonatology, Erciyes University School of Medicine, Kayseri, Turkey
Fetal Pediatr Pathol 30:363-9. 2011
..To our knowledge, this is the first report of a patient in whom ScFN occurred during a commonly performed and relatively short-term "nonhypothermic" operation...
- Thyroid hypoplasia as a cause of congenital hypothyroidism in monozygotic twins concordant for Rubinstein-Taybi syndrome
Mustafa Ali Akin
Erciyes University, Faculty of Medicine, Department of Pediatrics, Division of Neonatology, Kayseri, Turkey
J Clin Res Pediatr Endocrinol 3:32-5. 2011
..The infants were discharged planning their follow-up by both endocrinology and cardiology units. The rarity of cases of twins with RSTS (concordant) co-existing with CH led us to present this report...
- Iodine overload and severe hypothyroidism in two neonates
Selim Kurtoglu
Erciyes University, Faculty of Medicine, Department of Pediatrics, Division of Neonatology, 38039 Kayseri, Turkey
J Clin Res Pediatr Endocrinol 1:275-7. 2009
..Presenting the two cases, we wanted to draw attention to these preventable causes of hypothyroidism in infants...
- Increased endothelial microparticles in obese and overweight children
Zubeyde Gunduz
Faculty of Medicine, Department of Pediatric Nephrology, Erciyes University, 38039 Kayseri, Turkey
J Pediatr Endocrinol Metab 25:1111-7. 2012
..In this study, we aimed to evaluate circulating EMPs in obese and overweight children and to disclose the measure of obesity with the strongest relation with circulating microparticles and carotid atherosclerosis...
- Congenital hypothyroidism due to maternal radioactive iodine exposure during pregnancy
Selim Kurtoglu
Erciyes University Faculty of Medicine, Department of Pediatrics, Division of Neonatology, Kayseri, Turkey
J Clin Res Pediatr Endocrinol 4:111-3. 2012
..55 pg/mL, free thyroxine 2.9 pg/mL, TSH 452 mU/L, thyroglobulin 20.1 ng/mL). The thyroid gland could not be visualized by ultrasonography. L-thyroxine treatment was initiated...
- Neonatal sludge: a finding of congenital hypothyroidism
Selim Kurtoglu
Erciyes University Faculty of Medicine, Department of Pediatrics, Division of Neonatology, 38039 Kayseri, Turkey
J Clin Res Pediatr Endocrinol 1:197-200. 2009
..We report herein a case of congenital hypothyroidism, who presented with icterus accompanied with sludge formation into the gallbladder, which disappeared after treatment with L-thyroxine...
- Fetal-neonatal ovarian cysts--their monitoring and management: retrospective evaluation of 20 cases and review of the literature
Mustafa Ali Akin
Erciyes University Faculty of Medicine, Department of Pediatrics, Division of Neonatology, 38039 Kayseri, Turkey
J Clin Res Pediatr Endocrinol 2:28-33. 2010
..A standard guide to management, treatment and follow-up of NOC is not yet available. The aim of this study was to evaluate retrospectively the records of NOC patients from two medical centers...
