Morikazu Akamine

Summary

Publications

  1. ncbi request reprint Necrotizing fasciitis caused by Pseudomonas aeruginosa
    Morikazu Akamine
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, University of the Ryukyus, Okinawa
    Intern Med 47:553-6. 2008
  2. pmc Mechanisms of Legionella pneumophila-induced interleukin-8 expression in human lung epithelial cells
    Hiromitsu Teruya
    Division of Molecular Virology and Oncology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903 0215, Japan
    BMC Microbiol 7:102. 2007
  3. doi request reprint Legionella pneumonia caused by Legionella pneumophila serogroup 2: second case report in Japan
    Makoto Furugen
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903 0215, Japan
    J Infect Chemother 14:161-5. 2008
  4. pmc Legionella pneumophila infection induces programmed cell death, caspase activation, and release of high-mobility group box 1 protein in A549 alveolar epithelial cells: inhibition by methyl prednisolone
    Makoto Furugen
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara Town, Okinawa 903 0215, Japan
    Respir Res 9:39. 2008
  5. doi request reprint Detection of Legionella pneumophila serogroup 1 antigen in respiratory samples using an immunochromatographic membrane test
    Futoshi Higa
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, University of the Ryukyus, Okinawa 903 0215, Japan
    J Microbiol Methods 74:121-2. 2008
  6. pmc Hepatocyte growth factor levels in Legionella pneumonia: a retrospective study
    Futoshi Higa
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Okinawa 903 0215, Japan
    BMC Infect Dis 11:74. 2011
  7. ncbi request reprint Intravenous ciprofloxacin versus erythromycin in the treatment of Legionella pneumonia
    Shusaku Haranaga
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
    Intern Med 46:353-7. 2007
  8. ncbi request reprint [A-DROP system might result in underestimation of severity of cases with Legionnaires' disease]
    Shusaku Haranaga
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Disease First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus
    Nihon Kokyuki Gakkai Zasshi 46:351-5. 2008
  9. ncbi request reprint Interferon-gamma reverses the evasion of Birc1e/Naip5 gene mediated murine macrophage immunity by Legionella pneumophila mutant lacking flagellin
    Morikazu Akamine
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan
    Microbiol Immunol 51:279-87. 2007
  10. ncbi request reprint In vitro activity of sitafloxacin against clinical strains of Streptococcus pneumoniae with defined amino acid substitutions in QRDRs of gyrase A and topoisomerase IV
    Masato Touyama
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara cho, Okinawa 903 0215, Japan
    J Antimicrob Chemother 58:1279-82. 2006

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Necrotizing fasciitis caused by Pseudomonas aeruginosa
    Morikazu Akamine
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, University of the Ryukyus, Okinawa
    Intern Med 47:553-6. 2008
    ..aeruginosa. This is a rare case and its clinical presentation was atypical. The clinical diagnosis of this infection may be difficult, and therefore such cases warrant the careful attention of physicians...
  2. pmc Mechanisms of Legionella pneumophila-induced interleukin-8 expression in human lung epithelial cells
    Hiromitsu Teruya
    Division of Molecular Virology and Oncology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903 0215, Japan
    BMC Microbiol 7:102. 2007
    ..We investigated the effect of L. pneumophila on the expression of interleukin-8 (IL-8) in human A549 alveolar and NCI-H292 tracheal epithelial cell lines...
  3. doi request reprint Legionella pneumonia caused by Legionella pneumophila serogroup 2: second case report in Japan
    Makoto Furugen
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903 0215, Japan
    J Infect Chemother 14:161-5. 2008
    ..This was considered to be the causative organism. In our literature search, this was only the second case of Legionella pneumonia caused by Legionella pneumophila serogroup 2 in Japan...
  4. pmc Legionella pneumophila infection induces programmed cell death, caspase activation, and release of high-mobility group box 1 protein in A549 alveolar epithelial cells: inhibition by methyl prednisolone
    Makoto Furugen
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara Town, Okinawa 903 0215, Japan
    Respir Res 9:39. 2008
    ..In this study, we investigated the precise mechanism by which A549 alveolar epithelial cells induced by L. pneumophila undergo apoptosis. We also studied the effect of methyl prednisolone on apoptosis in these cells...
  5. doi request reprint Detection of Legionella pneumophila serogroup 1 antigen in respiratory samples using an immunochromatographic membrane test
    Futoshi Higa
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, University of the Ryukyus, Okinawa 903 0215, Japan
    J Microbiol Methods 74:121-2. 2008
    ..The ICT results using respiratory samples agreed well with isolation of L. pneumophila SG1 and ICT using urines...
  6. pmc Hepatocyte growth factor levels in Legionella pneumonia: a retrospective study
    Futoshi Higa
    Department of Infectious, Respiratory, and Digestive Medicine, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Okinawa 903 0215, Japan
    BMC Infect Dis 11:74. 2011
    ..Legionella pneumonia is sometimes complicated by acute lung injury. Our study aimed to determine the role of serum HGF levels in Legionella pneumonia...
  7. ncbi request reprint Intravenous ciprofloxacin versus erythromycin in the treatment of Legionella pneumonia
    Shusaku Haranaga
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
    Intern Med 46:353-7. 2007
    ..In this study, we compared the evolution of patients with Legionella pneumonia treated with CPFX to those treated with EM...
  8. ncbi request reprint [A-DROP system might result in underestimation of severity of cases with Legionnaires' disease]
    Shusaku Haranaga
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Disease First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus
    Nihon Kokyuki Gakkai Zasshi 46:351-5. 2008
    ..However all the fatal cases were ranked as severe in the IDSA guidelines. This study suggested that the A-DROP system might underestimate the severity of pneumonia in cases with legionella pneumonia...
  9. ncbi request reprint Interferon-gamma reverses the evasion of Birc1e/Naip5 gene mediated murine macrophage immunity by Legionella pneumophila mutant lacking flagellin
    Morikazu Akamine
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan
    Microbiol Immunol 51:279-87. 2007
    ..These findings suggested that IFN-gamma activated macrophages to restrict the intracellular growth of the L. pneumophila flaA mutant by a NO independent pathway...
  10. ncbi request reprint In vitro activity of sitafloxacin against clinical strains of Streptococcus pneumoniae with defined amino acid substitutions in QRDRs of gyrase A and topoisomerase IV
    Masato Touyama
    Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara cho, Okinawa 903 0215, Japan
    J Antimicrob Chemother 58:1279-82. 2006
    ..In vitro activities of sitafloxacin were evaluated against clinical isolates of S. pneumoniae resistant to levofloxacin (MIC of levofloxacin > or = 4 mg/L), which were characterized genetically...