Mohamed H Ahmed

Summary

Publications

  1. ncbi request reprint The effect of chloroquine on renal function and vasopressin secretion: a nitric oxide-dependent effect
    Mohamed H Ahmed
    School of Biological Sciences, University of Manchester, Manchester, United Kingdom
    J Pharmacol Exp Ther 304:156-61. 2003
  2. ncbi request reprint Cytomorphologic patterns of breast lesions in Sudanese patients: lessons learned from fine needle aspiration cytology
    Ahmed Omer Almobarak
    Department of Pathology, Faculty of Medicine, University of Medical Sciences and Technology, Khartoum, Sudan E mail
    Asian Pac J Cancer Prev 15:3411-3. 2014
  3. pmc The relationship between nonalcoholic fatty liver disease and colorectal cancer: the future challenges and outcomes of the metabolic syndrome
    Said O Muhidin
    Department of Ophthalmology, Southampton University Hospitals, Southampton SO16 6YD, UK
    J Obes 2012:637538. 2012
  4. doi request reprint Renal stone disease and obesity: what is important for urologists and nephrologists?
    Mohamed H Ahmed
    Department of Medicine, Wexham Park Hospital, Slough, Berkshire, UK
    Ren Fail 34:1348-54. 2012
  5. pmc Nonalcoholic fatty liver disease and cardiovascular disease: has the time come for cardiologists to be hepatologists?
    Mohamed H Ahmed
    Department of Medicine, Wexham Park Hospital, Berkshire, Slough, UK
    J Obes 2012:483135. 2012
  6. doi request reprint The safety and effectiveness of statins as treatment for HIV-dyslipidemia: the evidence so far and the future challenges
    Mohamed H Ahmed
    The James Cook University Hospital, Division of Acute Medicine, Middlesbrough TS4 3BW, UK
    Expert Opin Pharmacother 13:1901-9. 2012
  7. pmc Moderate ischemic mitral regurgitation (IMR) and metabolic syndrome: where are we now and where are we going?
    Khalid A Osman
    Department of Surgery, Queen s Hospital, Burton on Trent, Staffordshire, UK
    Cardiovasc Diabetol 5:24. 2006
  8. ncbi request reprint Torcetrapib as potential treatment of low high-density lipoprotein cholesterol: no longer a pipe dream?
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton General Hospital, Southampton, United Kingdom
    Diabetes Technol Ther 10:328-9. 2008
  9. pmc Ezetimbe as potential treatment for cholesterol gallstones: The need for clinical trials
    Mohamed H Ahmed
    Chemical Pathology Department, Mail point 6 Level D, South Academic Block, Southampton University Hospitals NHS Trust, Southampton SO16 6YD, United Kingdom
    World J Gastroenterol 16:1555-7. 2010
  10. doi request reprint Niacin as potential treatment for dyslipidemia and hyperphosphatemia associated with chronic renal failure: the need for clinical trials
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton University Hospitals NHS Trust, Southampton SO16 6YD, UK
    Ren Fail 32:642-6. 2010

Collaborators

  • Christopher D Byrne
  • Khalid A Osman
  • Kimberley D Bruce
  • N Ashton
  • Ahmed Omer Almobarak
  • Ahmed O Almobarak
  • Shuja Hafeez
  • Asma A Hamad
  • Said O Muhidin
  • Rasheed A Saad
  • Meissa M Osman
  • Heitham Mohammed Awadalla
  • Wadie Mohamed Yasin Elmadhoun
  • Tayseer M Elhassan
  • Taiseer Mohamed Elhassan
  • Mai H Khalifa
  • Mohamed Hassan Elhoweris
  • Mohamed H Elhoweris
  • Salma Barakat
  • Shareef Syed
  • Vincent Connolly
  • Atif A Khalil
  • Ahmed A Magan
  • Amr A Fahmy

Detail Information

Publications40

  1. ncbi request reprint The effect of chloroquine on renal function and vasopressin secretion: a nitric oxide-dependent effect
    Mohamed H Ahmed
    School of Biological Sciences, University of Manchester, Manchester, United Kingdom
    J Pharmacol Exp Ther 304:156-61. 2003
    ..These data suggest that chloroquine may stimulate nitric-oxide synthase both centrally, stimulating vasopressin secretion, and within the kidney, where it modulates glomerular hemodynamics and tubular function...
  2. ncbi request reprint Cytomorphologic patterns of breast lesions in Sudanese patients: lessons learned from fine needle aspiration cytology
    Ahmed Omer Almobarak
    Department of Pathology, Faculty of Medicine, University of Medical Sciences and Technology, Khartoum, Sudan E mail
    Asian Pac J Cancer Prev 15:3411-3. 2014
    ..Cytology for breast lesions is a safe, rapid and cost-effective with a high specificity and sensitivity...
  3. pmc The relationship between nonalcoholic fatty liver disease and colorectal cancer: the future challenges and outcomes of the metabolic syndrome
    Said O Muhidin
    Department of Ophthalmology, Southampton University Hospitals, Southampton SO16 6YD, UK
    J Obes 2012:637538. 2012
    ....
  4. doi request reprint Renal stone disease and obesity: what is important for urologists and nephrologists?
    Mohamed H Ahmed
    Department of Medicine, Wexham Park Hospital, Slough, Berkshire, UK
    Ren Fail 34:1348-54. 2012
    ..Further research is urgently needed to address the pathophysiology and management of obesity-induced renal stones disease...
  5. pmc Nonalcoholic fatty liver disease and cardiovascular disease: has the time come for cardiologists to be hepatologists?
    Mohamed H Ahmed
    Department of Medicine, Wexham Park Hospital, Berkshire, Slough, UK
    J Obes 2012:483135. 2012
    ..Importantly, the current evidence suggest that statins are safe and effective treatment for CVD in individuals with NAFLD...
  6. doi request reprint The safety and effectiveness of statins as treatment for HIV-dyslipidemia: the evidence so far and the future challenges
    Mohamed H Ahmed
    The James Cook University Hospital, Division of Acute Medicine, Middlesbrough TS4 3BW, UK
    Expert Opin Pharmacother 13:1901-9. 2012
    ....
  7. pmc Moderate ischemic mitral regurgitation (IMR) and metabolic syndrome: where are we now and where are we going?
    Khalid A Osman
    Department of Surgery, Queen s Hospital, Burton on Trent, Staffordshire, UK
    Cardiovasc Diabetol 5:24. 2006
    ..Interestingly metabolic syndrome showed more pronounced alteration of left ventricular geometry and function especially in obese subjects...
  8. ncbi request reprint Torcetrapib as potential treatment of low high-density lipoprotein cholesterol: no longer a pipe dream?
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton General Hospital, Southampton, United Kingdom
    Diabetes Technol Ther 10:328-9. 2008
  9. pmc Ezetimbe as potential treatment for cholesterol gallstones: The need for clinical trials
    Mohamed H Ahmed
    Chemical Pathology Department, Mail point 6 Level D, South Academic Block, Southampton University Hospitals NHS Trust, Southampton SO16 6YD, United Kingdom
    World J Gastroenterol 16:1555-7. 2010
    ..Further studies are required before the use of ezetimibe for the treatment of gallstones can be advocated...
  10. doi request reprint Niacin as potential treatment for dyslipidemia and hyperphosphatemia associated with chronic renal failure: the need for clinical trials
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton University Hospitals NHS Trust, Southampton SO16 6YD, UK
    Ren Fail 32:642-6. 2010
    ..Further studies are required before the use of niacin for the treatment of both dyslipidemia and hyperphosphatemia with CKD advocated...
  11. doi request reprint What does the future hold for niacin as a treatment for hyperlipidaemia and cardiovascular disease?
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton University Hospitals NHS Trust, Southampton, UK
    J Cardiovasc Med (Hagerstown) 11:858-60. 2010
    ..Importantly, the impact of niacin and statin on insulin sensitivity is not yet known. This article projects the potential benefits of current and possible future niacin clinical trials...
  12. doi request reprint Orlistat and calcium oxalate crystalluria: an association that needs consideration
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton University Hospitals, Southampton, UK
    Ren Fail 32:1019-21. 2010
    ..The focus of this article is to review current studies showing impact of orlistat on renal function and outcomes...
  13. ncbi request reprint Ezetimibe as a potential treatment for dyslipidemia associated with chronic renal failure and renal transplant
    Mohamed H Ahmed
    Division of Acute Medicine, The James Cook University Hospital, Marton Road, Middlesbrough, United Kingdom
    Saudi J Kidney Dis Transpl 21:1021-9. 2010
    ..Future clinical trials are needed to determine whether ezetimibe will reduce cardiovascular risk in the CKD patients...
  14. ncbi request reprint Chloroquine-induced nitric oxide as a potential treatment of erectile dysfunction associated with the metabolic syndrome: the science and the fiction
    Mohamed H Ahmed
    Southampton General Hospital, Chemical Pathology Department, Mail Point 6, Level D, South Academic Block, Tremona Road, Southampton, SO16 6YD, UK
    Expert Opin Emerg Drugs 12:191-3. 2007
    ..Chloroquine was also postulated to enhance insulin sensitivity, which suggests potential benefit in treating the metabolic syndrome-related erectile dysfunction...
  15. ncbi request reprint Rimonabant as potential treatment for the neglected epidemic of diabetes in the Middle East and Arabian Peninsula. Implication for prevention
    Mohamed H Ahmed
    Department of Chemical Pathology, Southampton General Hospital, Southampton, United Kingdom
    Saudi Med J 28:806-8. 2007
  16. ncbi request reprint Why does chloroquine impair renal function?: chloroquine may modulate the renal tubular response to vasopressin either directly by inhibiting cyclic AMP generation, or indirectly via nitric oxide
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton General Hospital, Tremona Road, Southampton, Hamphshire SO16 6YD, UK
    Med Hypotheses 68:140-3. 2007
    ..Chloroquine appears to modulate the renal tubular response to vasopressin either by directly inhibiting cAMP generation or indirectly via NO...
  17. ncbi request reprint Improving laboratory diagnosis of diabetic nephropathy with the use of glomerular filtration rate
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton General Hospital, Southampton, UK
    Diabetes Technol Ther 8:688-90. 2006
  18. doi request reprint Ezetimibe as a potential treatment for non-alcoholic fatty liver disease: is the intestine a modulator of hepatic insulin sensitivity and hepatic fat accumulation?
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton University Hospital NHS Trust, Southampton SO16 6YD, UK
    Drug Discov Today 15:590-5. 2010
    ..We suggest, therefore, that urgent studies are needed to assess the potential therapeutic benefit of ezetimibe in treating NAFLD...
  19. pmc Bariatric surgery as potential treatment for nonalcoholic fatty liver disease: a future treatment by choice or by chance?
    Shuja Hafeez
    Department of Emergency Medicine, The James Cook University Hospital, Middlesbrough TS4 3BW, UK
    J Obes 2013:839275. 2013
    ..The outcomes of the future research will determine whether bariatric surgery will be one of the recommended choice for treatment of the most progressive type of NAFLD...
  20. doi request reprint Relationship between non-alcoholic fatty liver disease and kidney function: a communication between two organs that needs further exploration
    Asma A Hamad
    Division of Acute Medicine, The James Cook University Hospital, Middlesbourgh, UK
    Arab J Gastroenterol 13:161-5. 2012
    ....
  21. ncbi request reprint Metabolic disturbances in non-alcoholic fatty liver disease
    Christopher D Byrne
    Endocrinology and Metabolism Unit, Institute for Developmental Sciences, University of Southampton and Southampton University Hospitals Trust, Southampton General Hospital, Southampton SO16 6YD, UK
    Clin Sci (Lond) 116:539-64. 2009
    ....
  22. doi request reprint Bariatric surgery and renal function: a precarious balance between benefit and harm
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton University Hospitals NHS Trust, Southampton, UK
    Nephrol Dial Transplant 25:3142-7. 2010
    ..The main risk factor for nephrolithiasis is increased excretion of urinary oxalate. In this review, we discuss the association between bariatric surgery, an increased risk of renal stone formation and oxalate nephropathy...
  23. doi request reprint Non-Alcoholic Fatty Liver Disease (NAFLD): new challenge for general practitioners and important burden for health authorities?
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton University Hospital NHS Trust, Southampton, UK
    Prim Care Diabetes 4:129-37. 2010
    ....
  24. doi request reprint Statins as potential treatment for cholesterol gallstones: an attempt to understand the underlying mechanism of actions
    Mohamed H Ahmed
    The James Cook University Hospital, Cardiothoracic Division, Department of Cardiology, Marton Road, Middlesbrough TS4 3BW, UK
    Expert Opin Pharmacother 12:2673-81. 2011
    ..Cholesterol gallstones are a common problem, resulting in hospital admission and surgery, throughout western healthcare systems...
  25. doi request reprint Current treatment of non-alcoholic fatty liver disease
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton University Hospitals NHS Trust, Southampton General Hospital, Southampton, UK
    Diabetes Obes Metab 11:188-95. 2009
    ..The potential benefit of bariatric surgery and the role of weight loss per se in treating NAFLD are also discussed...
  26. ncbi request reprint The association between renal stone disease and cholesterol gallstones: the easy to believe and not hard to retrieve theory of the metabolic syndrome
    Mohamed H Ahmed
    Department of Medicine, Milton Keynes Hospital NHS Foundation Trust, Eaglestone, Milton Keynes, Buckinghamshire, UK
    Ren Fail 36:957-62. 2014
    ..Further research is needed to determine: (i) the underlying mechanisms of renal stone disease and gallstone disease; (ii) the potential treatment of renal stone disease and gallstone disease. ..
  27. doi request reprint Non alcoholic fatty liver disease (NAFLD) in a Sudanese population: What is the prevalence and risk factors?
    Ahmed O Almobarak
    Department of Pathology, Faculty of Medicine, University of Medical Sciences and Technology, Khartoum, Sudan
    Arab J Gastroenterol 15:12-5. 2014
    ....
  28. doi request reprint Emergency colectomy for fulminant Clostridium difficile colitis: Striking the right balance
    Khalid A Osman
    Department of Surgery, The James Cook University Hospital, Middlesbrough, UK
    Scand J Gastroenterol 46:1222-7. 2011
    ..Ultimately, this may reduce the significant morbidity and mortality associated with FCDC...
  29. ncbi request reprint Fatal fat embolism complicating cemented total knee replacement: another manifestation of the metabolic syndrome?
    Rasheed A Saad
    The Wessex Cardiothoracic Unit, Southampton General Hospital, Southampton, UK
    Arch Orthop Trauma Surg 127:387-9. 2007
    ....
  30. ncbi request reprint Biochemical markers: the road map for the diagnosis of nonalcoholic fatty liver disease
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton General Hospital, Southampton, UK
    Am J Clin Pathol 127:20-2. 2007
  31. ncbi request reprint Modulation of sterol regulatory element binding proteins (SREBPs) as potential treatments for non-alcoholic fatty liver disease (NAFLD)
    Mohamed H Ahmed
    Chemical Pathology Department, Southampton General Hospital, Southampton, UK
    Drug Discov Today 12:740-7. 2007
    ..We suggest that further studies are urgently needed to evaluate modulation of SREBP activity as a potential new treatment for NAFLD...
  32. pmc Diabetes and Ramadan: an update on use of glycemic therapies during fasting
    Mohamed H Ahmed
    Department of Cardiology, Cardiothoracic Division, The James Cook University Hospital, UK
    Ann Saudi Med 31:402-6. 2011
    ..Further clinical trials are needed to evaluate the safety and efficacy of new antidiabetic agents and new diabetes-related technologies during Ramadan...
  33. ncbi request reprint Rimonabant as a potential new treatment for an emerging epidemic of obesity-related glomerulopathy?
    Mohamed H Ahmed
    Expert Opin Emerg Drugs 11:563-5. 2006
    ..Rimonabant, a new antiobesity medication, showed beneficial potential effect in treating clusters of metabolic syndrome, which may ultimately suggest potential benefit in treating obesity-related glomerulopathy...
  34. ncbi request reprint Renal function in a rat model of analgesic nephropathy: effect of chloroquine
    Mohamed H Ahmed
    School of Biological Sciences, University of Manchester, Manchester, United Kingdom
    J Pharmacol Exp Ther 305:123-30. 2003
    ..However, these responses contrast with the chloroquine-induced diuresis previously observed in untreated rats, possibly reflecting paracetamol inhibition of renal prostaglandin synthesis and consequent moderation of vasopressin's action...
  35. ncbi request reprint Ezetimibe: effective and safe treatment for dyslipidaemia associated with nonalcoholic fatty liver disease. Response to: Toth PP, Davidson MH: simvastatin and ezetimibe: combination therapy for the management of dyslipidaemia. Expert Opin. Pharmacother. (
    Mohamed H Ahmed
    Expert Opin Drug Saf 5:487-8. 2006
  36. ncbi request reprint Heart failure as a consequence of ischemic mitral regurgitation (IMR): the hidden threat of the metabolic syndrome
    Meissa M Osman
    Med Hypotheses 67:193-4. 2006
  37. ncbi request reprint Renal action of acute chloroquine and paracetamol administration in the anesthetized, fluid-balanced rat
    Mohamed H Ahmed
    School of Biological Sciences, University of Manchester, Manchester M13 9PT, UK
    J Pharmacol Exp Ther 306:478-83. 2003
    ....
  38. ncbi request reprint Metabolic syndrome and ischemic mitral regurgitation: other piece of the jigsaw
    Khalid A Osman
    Asian Cardiovasc Thorac Ann 14:354-5. 2006
  39. ncbi request reprint Insulin resistance and nitric oxide and associated renal injury: innocent bystanders or accessories to the crime?
    Mohamed H Ahmed
    N Z Med J 119:U2112. 2006