AHMED AHMED

Summary

Affiliation: Zoology department, Faculty of Science, Beni-Suef University, Egypt.
Location: beni-suef, Egypt
URL: none
Summary:
Both maternal administrations of dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) during gestation and lactation periods may impair the development of cerebellum of their offspring via thyroid hormones and this may, in general, delay the growth and differentiation of the neuroendocrine system.
● Dioxin may act as endocrine- and neural-disrupting actions on the development of THs-cerebellum axis.
●The long-term effects of diabetes during the pregnancy (gestational diabetes) may influence, generally, on the health of the embryos, newborns (perinatal life) and adulthood.
● Sperm, egg, zygote or blastocyst derived from diabetic parents may develop into offspring with high risk of any type of diabetes, even if placed in a normal uterus, producing developmental delay, embryopathy, geno-and cyto-toxicity, teratogenic changes, free radicals and apoptosis.
Grants:
2012 GRANT FROM SOCIETY OF ENDOCRINOLOGY.
2011 Honor from Society for Endocrinology in project of .
03-12/20111 Grant from Onderzoeksraad (Research Council) of the Katholieke University, Leuven.
03/2010-02/2011 Grant from Science and Technology Development Fund Program (STDF), Egypt
12/08-13/2009 Grant from the Society of Neuroscientists of Africa (SONA) and Fayoum University for the 9th international conference of SONA, in Sharm El Sheikh, Egypt.
12/02-06/2009 Grant from the International Society for Neurochemistry (ISN), International Brain Research Organization (IBRO) and Fayoum University (Egypt) to get the 21st IBRO Africa schools course, in Fayoum University.
2006-2008 Graduate student research assistantship, Zoology Department, Faculty of Science, Beni-Suef University, Egypt.
2007 International Computer Driving Licence (ICDL) (Serial Number is UN 07 06 4224).
12/2006-6/2007 Fellowship from the Egyptian ministry of higher education.
2001-2005 Graduate student research assistantship, Zoology Department, Faculty of Science, Cairo University, Beni-Suef branch, Egypt.
2001 Excellent grade in cell biology, histology and genetics branch among all M.Sc. students, Faculty of Science, Cairo University.
2001 Member in Egyptian Syndicate of Scientific Professions, Egypt.
2000 Highest grade in the Zoology-Chemistry Department, Cairo University, Beni-Suef branch, Egypt.
Publications:
1.) Ahmed, O.M., R. G. Ahmed, 2011. Chapter in Hypothyroidism/Book 1/ISBN 978-953-307-758-1. INTECH OPEN ACCESS PUBLISHER, University Campus, STeP Ri Slavka Krautzeka 83/A 51000 Rijeka, Croatia. In press.
2.) Ahmed, R.G., 2011. Perinatal 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure alters developmental neuroendocrine system. J. of Food and Chemical Toxicol. 49, 1276–1284.
3.) Ahmed, R.G., 2011. Evolutionary interactions between diabetes and development. Diabetes Res. and Clin. Pract. 92, 153-167.
4.) El-bakry, A.M., El-Ghareeb, A-W. A., Ahmed, R.G., 2010. Comparative study of the effects of experimentally-induced hypothyroidism and hyperthyroidism in some brain regions in albino rats. Int. J. Dev. Neurosci. 28, 371-389.
5.) Ahmed, O.M., Abd El-Tawab, S.M., Ahmed, R.G., 2010. Effects of experimentally-induced maternal hypothyroidism and hyperthyroidism on the development of rat newborns: I- The development of the thyroid hormones-neurotransmitters and adenosinergic system interactions. Int. J. Dev. Neurosci. 28, 437-454.
6.) El-Ghareeb, A-W. A., Abd El-Tawab, S.M., El-bakry, A.M., Ahmed, R.G., 2010. Effects of experimentally-induced hypothyroidism and hyperthyroidism in pregnant albino rats: II- The developmental pattern of neurons-reactive oxygen species generation and antioxidative defense status in brain of their newborns. J. Egypt. Ger. Soc. Zool., part of Vertebrate Anatomy and Embryology 61B, 1-57 (www.egsz.org).
7.) Ahmed, O.M., El-Gareib, A.W., El-bakry, A.M., Abd El-Tawab, S.M., Ahmed, R.G., 2008. Thyroid hormones states and brain development interactions. Int. J. Dev. Neurosci. 26(2), 147-209.
8.) Ahmed, O.M., Nada, M.M., Ahmed, R.G., 2007. Does the heat stress deteriorate the neurons development in albino rat newborns? Asian J. animal sci. and vet. 2(3), 86-103.
9.) Ahmed, O.M., Bahgat, M., Ahmed, R.G., 2007. Age and heat stress related changes in monoamine contents and cholinesterase activity in some central nervous system regions of albino rat newborns. Int. J. Zool. Res. 3(2), 65-76.
10.) Ahmed, R.G., 2006. The relation between biological consequences and temperature in mammals. Int. J. Zool. Res. 2(1), 48-59.
11.) Ahmed, R.G., 2006. The relation between biological consequences and temperature on some non-mammalian species. Int. J. Zool. Res. 2(2), 136-149.
12.) Ahmed, R.G., 2006. Damage patterns as a function of various types of radiation. Int. J. Zool. Res. 2(2), 150-168.
13.) Ahmed, R.G., Ma, Y.Y., Lee, S.H., 2006. Peroxiredoxins and neurodegeneration. Int. J. Zool. Res. 2(3), 226-241.
14.) Ahmed, R.G., 2005. Heat stress induced histopathology and pathophysiology of the central nervous system. Int. J. Dev. Neurosci. 23(6), 549-557.
15.) Ahmed, R.G., 2005. Is there a balance between oxidative stress and antioxidant defense system during development? Med. J. Islamic Academy of Sci. 15(2), 55-63.
16.) Ahmed, R.G., 2005. The physiological and biochemical effects of diabetes on the balance between oxidative stress and antioxidant defense system. Med. J. of Islamic Academy of Sci. 15(1), 31-42.

Publications

  1. Ahmed R. Heat stress induced histopathology and pathophysiology of the central nervous system. Int J Dev Neurosci. 2005;23:549-57 pubmed
    ..Thus, further studies need to be done to emphasize this concept. ..
  2. Ahmed O, El Gareib A, El Bakry A, Abd El Tawab S, Ahmed R. Thyroid hormones states and brain development interactions. Int J Dev Neurosci. 2008;26:147-209 pubmed
    ..Thus, further studies need to be done to emphasize this concept...
  3. El Bakry A, El Gareib A, Ahmed R. Comparative study of the effects of experimentally induced hypothyroidism and hyperthyroidism in some brain regions in albino rats. Int J Dev Neurosci. 2010;28:371-89 pubmed publisher
    ..These alterations, on both treated groups, were age and dose dependent. Thus, further studies need to be done to emphasize this concept. ..
  4. Ahmed R, Abdel Latif M, Ahmed F. Protective effects of GM-CSF in experimental neonatal hypothyroidism. Int Immunopharmacol. 2015;29:538-543 pubmed publisher
    ..05) at tested PND. Thus, neonatal GM-CSF may be responsible for suppressing autoimmune responses and preventing hypothyroidism. ..
  5. Ahmed R. Gestational dexamethasone alters fetal neuroendocrine axis. Toxicol Lett. 2016;258:46-54 pubmed publisher
    ..These alterations were age-dependent and might damage the nerve transmission. Finally, maternal DEXA might act as neuroendocrine disruptor causing dyshormonogenesis and fetal cerebral dysfunction. ..
  6. Ahmed R. Maternal bisphenol A alters fetal endocrine system: Thyroid adipokine dysfunction. Food Chem Toxicol. 2016;95:168-74 pubmed publisher
    ..These alterations were dose dependent. Thus, BPA might penetrate the placental barrier and perturb the fetal thyroid adipokine axis to influence fat metabolism and the endocrine system. ..
  7. Ahmed R, El Gareib A. Maternal carbamazepine alters fetal neuroendocrine-cytokines axis. Toxicology. 2017;382:59-66 pubmed publisher
    ..These developmental changes were dose-dependent. These novel results suggest that CBZ may act as a developmental immunoneuroendocrine disruptor. ..

Collaborators

Detail Information

Publications7