Manzoor Ahmad

Summary

Publications

  1. ncbi request reprint New diterpenoid alkaloids from Aconitum heterophyllum Wall: Selective butyrylcholinestrase inhibitors
    Muhammad Nisar
    Institute of Chemical Sciences and Department of Pharmacy, University of Peshawar, Peshawar, Pakistan
    J Enzyme Inhib Med Chem 24:47-51. 2009
  2. doi request reprint Molecular interactions of 4-acetoxy-plakinamine B with peripheral anionic and other catalytic subsites of the aromatic gorge of acetylcholinesterase: computational and structural insights
    Inamullah Khan
    Department of Pharmacy, University of Peshawar, Peshawar, Pakistan
    Pharm Biol 51:722-7. 2013
  3. ncbi request reprint Preclinical profile of bacopasides from Bacopa monnieri (BM) as an emerging class of therapeutics for management of chronic pains
    K Rauf
    Department of Pharmaceutical Sciences, COMSATS Institute of Information Technology, Abbottabad, Pakistan
    Curr Med Chem 20:1028-37. 2013
  4. doi request reprint Anti-inflammatory activities of Sieboldogenin from Smilax china Linn.: experimental and computational studies
    Inamullah Khan
    Department of Pharmacy, University of Peshawar, Peshawar 25120, Pakistan
    J Ethnopharmacol 121:175-7. 2009
  5. doi request reprint Structural insights to investigate Conypododiol as a dual cholinesterase inhibitor from Asparagus adscendens
    Inamullah Khan
    Department of Pharmacy, University of Peshawar, Peshawar 25120, Pakistan
    Fitoterapia 81:1020-5. 2010
  6. doi request reprint Molecular simulations of Taxawallin I inside classical taxol binding site of β-tubulin
    Inamullah Khan
    Department of Pharmacy, University of Peshawar, Peshawar 25120, Pakistan
    Fitoterapia 82:276-81. 2011
  7. doi request reprint Anti-inflammatory activities of Taxusabietane A isolated from Taxus wallichiana Zucc
    Inamullah Khan
    Department of Pharmacy, University of Peshawar, 25120, Pakistan
    Fitoterapia 82:1003-7. 2011
  8. ncbi request reprint In vitro enzyme inhibition activities of crude ethanolic extracts derived from medicinal plants of Pakistan
    Somia Khattak
    Department of Chemistry, University of Peshawar, Peshawar 25120, Pakistan
    Nat Prod Res 19:567-71. 2005
  9. doi request reprint Urease inhibitors from Indigofera gerardiana Wall
    Shafiq Ahmad Tariq
    Department of Pharmacology Khyber Medical College, Peshawar, Pakistan
    J Enzyme Inhib Med Chem 26:480-4. 2011
  10. doi request reprint Anticonvulsant activity of DNS II fraction in the acute seizure models
    Muhammad Liaquat Raza
    H E J International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
    J Ethnopharmacol 128:600-5. 2010

Collaborators

  • Muhammad Saeed
  • Haroon Khan
  • - Obaidullah
  • Somia Khattak
  • Abdus Samad
  • M Iqbal Choudhary
  • Zafar Iqbal
  • Muhammad Arfan
  • Farzana Shaheen
  • Inamullah Khan
  • Muhammad Nisar
  • Syed Muhammad Abdullah
  • Waqar Ahmad Kaleem
  • Mughal Qayum
  • K Rauf
  • Shafiq Ahmad Tariq
  • Hamidullah Shah
  • Nematullah Khan
  • Muhammad Liaquat Raza
  • - Samiullah
  • Nasiara Karim
  • Said Nadeem
  • Abuzar Khan
  • I Khan
  • M R Shah
  • Amir Badshah
  • A Zarrelli
  • A M al-Othman
  • Muhammad Zia-Ul-Haq
  • F Subhan
  • Amir Zada Khan
  • Solomon Habtemariam
  • Naseem Ullah
  • Akhter Aman
  • Mohammad Ismail
  • Ajmal Khan
  • Syed Muhammad Ashhad Halimi
  • Waqar Ahmad
  • Muhammad Raza Shah
  • Farah Gul
  • Majeed Ullah
  • Syed Naeemuddin Gilani
  • - Fazal-ur-Rehman
  • Farooq Ali
  • Hanif Ahmad
  • Shabana U Simjee
  • Ihsan Ali Khan
  • Mohammad Zeeshan
  • Noreen Wadood
  • Zia Ahmad
  • Muhammad Arif Lodhi
  • Farooq Ebad
  • Fazli Khuda

Detail Information

Publications18

  1. ncbi request reprint New diterpenoid alkaloids from Aconitum heterophyllum Wall: Selective butyrylcholinestrase inhibitors
    Muhammad Nisar
    Institute of Chemical Sciences and Department of Pharmacy, University of Peshawar, Peshawar, Pakistan
    J Enzyme Inhib Med Chem 24:47-51. 2009
    ..24% and 6.94 % and 79.1 % and 82.75 % for AChE and BChE, respectively indicating that compounds 1 and 2 are about thirteen times more specific to BChE than AChE...
  2. doi request reprint Molecular interactions of 4-acetoxy-plakinamine B with peripheral anionic and other catalytic subsites of the aromatic gorge of acetylcholinesterase: computational and structural insights
    Inamullah Khan
    Department of Pharmacy, University of Peshawar, Peshawar, Pakistan
    Pharm Biol 51:722-7. 2013
    ..A steroidal alkaloid, 4-acetoxy-plakinamine B (4APB), is a recently discovered marine natural product with inhibitory effect against acetylcholinesterase (AChE), but its mechanism of interaction with the enzyme remains to be elucidated...
  3. ncbi request reprint Preclinical profile of bacopasides from Bacopa monnieri (BM) as an emerging class of therapeutics for management of chronic pains
    K Rauf
    Department of Pharmaceutical Sciences, COMSATS Institute of Information Technology, Abbottabad, Pakistan
    Curr Med Chem 20:1028-37. 2013
    ..This minireview evaluated the preclinical data that highlights potential of BM as a future candidate for clinical management of chronic pains...
  4. doi request reprint Anti-inflammatory activities of Sieboldogenin from Smilax china Linn.: experimental and computational studies
    Inamullah Khan
    Department of Pharmacy, University of Peshawar, Peshawar 25120, Pakistan
    J Ethnopharmacol 121:175-7. 2009
    ..Smilax china Linn. is extensively used in traditional Chinese medicine (TCM) as well as in Pakistan for several medicinal purposes including their use in inflammatory disorders...
  5. doi request reprint Structural insights to investigate Conypododiol as a dual cholinesterase inhibitor from Asparagus adscendens
    Inamullah Khan
    Department of Pharmacy, University of Peshawar, Peshawar 25120, Pakistan
    Fitoterapia 81:1020-5. 2010
    ..This preliminary study highlighted the potential of Conypododiol to be further developed and modified as new lead compound identified by its folk use...
  6. doi request reprint Molecular simulations of Taxawallin I inside classical taxol binding site of β-tubulin
    Inamullah Khan
    Department of Pharmacy, University of Peshawar, Peshawar 25120, Pakistan
    Fitoterapia 82:276-81. 2011
    ..Tubulin binding assay was performed to assess its tubulin binding activity. Molecular docking analysis was performed to study the potential binding mode inside the taxol binding site of β-tubulin...
  7. doi request reprint Anti-inflammatory activities of Taxusabietane A isolated from Taxus wallichiana Zucc
    Inamullah Khan
    Department of Pharmacy, University of Peshawar, 25120, Pakistan
    Fitoterapia 82:1003-7. 2011
    ..However, this study highlighted the potential of Taxusabietane A to be further explored as a new lead compound for management of conditions associated with inflammation...
  8. ncbi request reprint In vitro enzyme inhibition activities of crude ethanolic extracts derived from medicinal plants of Pakistan
    Somia Khattak
    Department of Chemistry, University of Peshawar, Peshawar 25120, Pakistan
    Nat Prod Res 19:567-71. 2005
    ....
  9. doi request reprint Urease inhibitors from Indigofera gerardiana Wall
    Shafiq Ahmad Tariq
    Department of Pharmacology Khyber Medical College, Peshawar, Pakistan
    J Enzyme Inhib Med Chem 26:480-4. 2011
    ..The urease inhibition studies on all the four compounds have also been carried out...
  10. doi request reprint Anticonvulsant activity of DNS II fraction in the acute seizure models
    Muhammad Liaquat Raza
    H E J International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
    J Ethnopharmacol 128:600-5. 2010
    ..e. DNS II acetone was chosen for further testing in the acute seizure models of epilepsy to study the antiepileptic potential in male mice...
  11. doi request reprint Standardization of pathology laboratories in Pakistan: problems and prospects
    Manzoor Ahmad
    College of Pathologists Pakistan, 175, Race Course Road, Rawalpindi, Pakistan
    Clin Biochem 42:259-62. 2009
    ..It is hoped that this simplified system will provide an impetus for evolving a workable and comprehensive mechanism through which pathology laboratories in the country will be able to offer better and more reliable services...
  12. ncbi request reprint New antibacterial pentacyclic triterpenes from Myricaria elegans Royle. (tamariscineae)
    Manzoor Ahmad
    H E J Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
    J Enzyme Inhib Med Chem 23:1023-7. 2008
    ..These compounds exhibited significant antibacterial activity. The structure of compounds 1 and 2 were deduced on the basis of their spectral analysis...
  13. ncbi request reprint Norditerpenoid alkaloids from the roots of Aconitum heterophyllum Wall with antibacterial activity
    Manzoor Ahmad
    H E J Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
    J Enzyme Inhib Med Chem 23:1018-22. 2008
    ..These compounds exhibited significant antibacterial activity. The structure of compound 1 and 2 were deduced on the basis of their spectral data...
  14. ncbi request reprint Urease inhibitor from Datisca cannabina linn
    Mansoor Ahmad
    Institute of Pharmaceutical Sciences, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan
    J Enzyme Inhib Med Chem 23:386-90. 2008
    ..cannabina Linn. The structure of compound 1 was deduced on the basis of its spectral data. Datisdirin showed activity against the ureases enzyme...
  15. ncbi request reprint Norditerpenoid alkaloids from Delphinium nordhagenii
    Farzana Shaheen
    H E J Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan
    J Nat Prod 69:823-5. 2006
    ..The structures of the new compounds 1 and 2 were also deduced on the basis of single-crystal X-ray diffraction studies...
  16. ncbi request reprint Alkaloids of Aconitum laeve and their anti-inflammatory antioxidant and tyrosinase inhibition activities
    Farzana Shaheen
    H E J Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Pakistan
    Phytochemistry 66:935-40. 2005
    ..The structure of compound 1 was deduced on the basis of spectral data. The anti-inflammatory, antioxidant and tyrosinase inhibition studies on all six compounds have also been carried out...
  17. doi request reprint Synthesis and antileishmanial and antimicrobial activities of some 2,3-disubstituted 3H-quinazolin-4-ones
    Muhammad Arfan
    Institute of Chemical Sciences, University of Peshawar, Peshawar, Pakistan
    J Enzyme Inhib Med Chem 25:451-8. 2010
    ..Compound 11 exhibited strongest leishmanicidal activity against Leishmania major (MHOM/PK/88/DESTO) promastigotes, while other compounds showed weak to moderate leishmanicidal activities...
  18. ncbi request reprint Biological effects of indigenous medicinal plants Curcuma longa and Alpinia galanga
    Somia Khattak
    Department of Chemistry, University of Peshawar, Pakistan
    Fitoterapia 76:254-7. 2005
    ..These extracts were found quite inert in antibacterial bioassay, while the extract from C. longa, tested for insecticidal activity, was also found to be devoid of any activity...