Amar Agha

Summary

Publications

  1. ncbi request reprint Target blood pressure for patients with type 2 diabetes is difficult to achieve in the setting of a busy diabetes clinic
    A Agha
    Department of Endocrinology and Diabetes Mellitus, James Connolly Memorial Hospital, Dublin, Ireland
    Ir J Med Sci 172:168-70. 2003
  2. ncbi request reprint Small-cell lung cancer presenting as diabetes insipidus and Cushing's syndrome
    Amar Agha
    Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
    Pituitary 8:105-7. 2005
  3. ncbi request reprint Parathyroid carcinoma in multiple endocrine neoplasia type 1 (MEN1) syndrome: two case reports of an unrecognised entity
    A Agha
    Departments of Endocrinology, St Bartholomew s Hospital, William Harvey Research Institute, Queen Mary University of London, London, UK
    J Endocrinol Invest 30:145-9. 2007
  4. ncbi request reprint Anterior pituitary dysfunction following traumatic brain injury (TBI)
    Amar Agha
    Department of Endocrinology, Division of Endocrinology and Diabetes, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
    Clin Endocrinol (Oxf) 64:481-8. 2006
  5. ncbi request reprint The natural history of post-traumatic hypopituitarism: implications for assessment and treatment
    Amar Agha
    Academic Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
    Am J Med 118:1416. 2005
  6. ncbi request reprint Acromegaly secondary to growth hormone releasing hormone secretion
    - Agha
    Department of Endocrinology, James Connolly Memorial Hospital, Dublin, Ireland
    Ir J Med Sci 173:215-6. 2004
  7. ncbi request reprint Hypothalamic-pituitary dysfunction after irradiation of nonpituitary brain tumors in adults
    Amar Agha
    Department of Endocrinology, Beaumont Hospital, Beaumont Road, Dublin 9, Ireland
    J Clin Endocrinol Metab 90:6355-60. 2005
  8. ncbi request reprint Anterior pituitary dysfunction in survivors of traumatic brain injury
    Amar Agha
    Academic Department of Endocrinology, Beaumont Hospital, Dublin 9, Ireland
    J Clin Endocrinol Metab 89:4929-36. 2004
  9. ncbi request reprint Posterior pituitary dysfunction after traumatic brain injury
    Amar Agha
    Academic Department of Endocrinology, Beaumont Hospital, Dublin 9, Ireland
    J Clin Endocrinol Metab 89:5987-92. 2004
  10. doi request reprint A comparison of osteoprotegerin with adiponectin and high-sensitivity C-reactive protein (hsCRP) as a marker for insulin resistance
    Eoin P O'Sullivan
    Department of Diabetes and Endocrinology, Royal College of Surgeons in Ireland Medical School, Beaumont Hospital, Dublin 9, Ireland
    Metabolism 62:34-8. 2013

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Target blood pressure for patients with type 2 diabetes is difficult to achieve in the setting of a busy diabetes clinic
    A Agha
    Department of Endocrinology and Diabetes Mellitus, James Connolly Memorial Hospital, Dublin, Ireland
    Ir J Med Sci 172:168-70. 2003
    ..Target blood pressure control in patients with type 2 diabetes should be 130/85 mmHg or less; however, it is not clear how achievable this target is in clinical practice...
  2. ncbi request reprint Small-cell lung cancer presenting as diabetes insipidus and Cushing's syndrome
    Amar Agha
    Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
    Pituitary 8:105-7. 2005
    ..This case is a remarkable example of the complex metabolic endocrine manifestations of small-cell lung cancer...
  3. ncbi request reprint Parathyroid carcinoma in multiple endocrine neoplasia type 1 (MEN1) syndrome: two case reports of an unrecognised entity
    A Agha
    Departments of Endocrinology, St Bartholomew s Hospital, William Harvey Research Institute, Queen Mary University of London, London, UK
    J Endocrinol Invest 30:145-9. 2007
    ..In this report, we describe two further cases of parathyroid carcinoma presenting in MEN1 syndrome...
  4. ncbi request reprint Anterior pituitary dysfunction following traumatic brain injury (TBI)
    Amar Agha
    Department of Endocrinology, Division of Endocrinology and Diabetes, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
    Clin Endocrinol (Oxf) 64:481-8. 2006
    ....
  5. ncbi request reprint The natural history of post-traumatic hypopituitarism: implications for assessment and treatment
    Amar Agha
    Academic Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
    Am J Med 118:1416. 2005
    ..We attempted to define the natural history of post-traumatic hypopituitarism to devise guidelines for the optimal timing of patients' assessment and hormone replacement...
  6. ncbi request reprint Acromegaly secondary to growth hormone releasing hormone secretion
    - Agha
    Department of Endocrinology, James Connolly Memorial Hospital, Dublin, Ireland
    Ir J Med Sci 173:215-6. 2004
    ..Acromegaly secondary to growth hormone releasing hormone (GHRH) secretion is exceptionally rare...
  7. ncbi request reprint Hypothalamic-pituitary dysfunction after irradiation of nonpituitary brain tumors in adults
    Amar Agha
    Department of Endocrinology, Beaumont Hospital, Beaumont Road, Dublin 9, Ireland
    J Clin Endocrinol Metab 90:6355-60. 2005
    ....
  8. ncbi request reprint Anterior pituitary dysfunction in survivors of traumatic brain injury
    Amar Agha
    Academic Department of Endocrinology, Beaumont Hospital, Dublin 9, Ireland
    J Clin Endocrinol Metab 89:4929-36. 2004
    ..Hypopituitarism is a treatable cause of morbidity after TBI. In addition to conventional pituitary hormone replacement, the potential of GH treatment to enhance recovery needs to be examined in a prospective study...
  9. ncbi request reprint Posterior pituitary dysfunction after traumatic brain injury
    Amar Agha
    Academic Department of Endocrinology, Beaumont Hospital, Dublin 9, Ireland
    J Clin Endocrinol Metab 89:5987-92. 2004
    ..Identification of patients with partial posttraumatic DI is important because appropriate treatment may reduce morbidity and optimize the potential for recovery...
  10. doi request reprint A comparison of osteoprotegerin with adiponectin and high-sensitivity C-reactive protein (hsCRP) as a marker for insulin resistance
    Eoin P O'Sullivan
    Department of Diabetes and Endocrinology, Royal College of Surgeons in Ireland Medical School, Beaumont Hospital, Dublin 9, Ireland
    Metabolism 62:34-8. 2013
    ..We aimed to compare the ability of serum OPG with adiponectin and hsCRP to act as a marker for IR in individuals with normal and abnormal glucose tolerance...
  11. doi request reprint Optimizing glucocorticoid replacement therapy in severely adrenocorticotropin-deficient hypopituitary male patients
    Lucy Ann Behan
    Division of Endocrinology, Beaumont Hospital and RCSI Medical School, Dublin, Ireland
    Clin Endocrinol (Oxf) 75:505-13. 2011
    ..Management strategies vary from treatment with 15-30 mg or higher in daily divided doses, reflecting the paucity of prospective data on the adequacy of different glucocorticoid regimens...
  12. doi request reprint The natural history of surgically treated but radiotherapy-naïve nonfunctioning pituitary adenomas
    Eoin P O'Sullivan
    Division of Neuro endocrinology, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
    Clin Endocrinol (Oxf) 71:709-14. 2009
    ..We aimed to define the natural history of a large, mainly unselected cohort with surgically treated, radiotherapy (RT)-naïve NFPAs and to try to identify predictors of recurrence/regrowth...
  13. ncbi request reprint Conventional glucocorticoid replacement overtreats adult hypopituitary patients with partial ACTH deficiency
    Amar Agha
    Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
    Clin Endocrinol (Oxf) 60:688-93. 2004
    ..Glucocorticoid therapy is associated with potentially serious side-effects, but there is no information available regarding glucocorticoid requirement in adult hypopituitary patients with partial ACTH deficiency...
  14. ncbi request reprint The incidence and pathophysiology of hyponatraemia after subarachnoid haemorrhage
    Mark Sherlock
    Department of Academic Endocrinology, National Neurosurgical Centre, Beaumont Hospital, Dublin 9, Ireland
    Clin Endocrinol (Oxf) 64:250-4. 2006
    ..Hyponatraemia is common following subarachnoid haemorrhage (SAH) but the pathogenesis is unclear. Objective To establish the incidence, pathophysiology and consequences of hyponatraemia following SAH...
  15. doi request reprint The interaction between growth hormone and the thyroid axis in hypopituitary patients
    Lucy Ann Behan
    Academic Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
    Clin Endocrinol (Oxf) 74:281-8. 2011
    ....
  16. ncbi request reprint Neuroendocrine dysfunction in the acute phase of traumatic brain injury
    Amar Agha
    Academic Department of Endocrinology, Beaumount Hospital, Dublin, Ireland
    Clin Endocrinol (Oxf) 60:584-91. 2004
    ..The frequency of pituitary dysfunction in the early post-TBI period is unknown...
  17. ncbi request reprint Spontaneous recovery from posttraumatic hypopituitarism
    Amar Agha
    From the Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
    Am J Phys Med Rehabil 84:381-5. 2005
    ....
  18. ncbi request reprint The natural history of post-traumatic neurohypophysial dysfunction
    Amar Agha
    Academic Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
    Eur J Endocrinol 152:371-7. 2005
    ..We report the results of a study designed to prospectively define the natural history of post-traumatic diabetes insipidus (DI) and syndrome of inappropriate antidiuretic hormone secretion (SIADH) using standard reliable methodology...
  19. doi request reprint Identifying coronary artery disease in men with type 2 diabetes: osteoprotegerin, pulse wave velocity, and other biomarkers of cardiovascular risk
    Colin Davenport
    Department of Diabetes and Endocrinology, Royal College of Surgeons in Ireland Medical School, Beaumont Hospital, Dublin, Ireland
    J Hypertens 29:2469-75. 2011
    ..The second aim was to compare OPG levels in patients with microvascular complications (microalbuminuria) against those with established CAD...
  20. ncbi request reprint Modulation of glucocorticoid metabolism by the growth hormone - IGF-1 axis
    Amar Agha
    Department of Endocrinology, St Bartholomew s Hospital William Harvey Research Institute, Queen Mary University of London, UK
    Clin Endocrinol (Oxf) 66:459-65. 2007
    ....
  21. doi request reprint The impact of pancreas and kidney transplant on cardiovascular risk factors (analyzed by mode of immunosuppression and exocrine drainage)
    Colin Davenport
    RCSI, Beaumont Endocrinology, Beaumont Hospital, Co Dublin, Ireland
    Clin Transplant 23:616-20. 2009
    ....
  22. ncbi request reprint Endocrine consequences of adult traumatic brain injury
    Lucy Ann Behan
    Division of Endocrinology, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
    Horm Res 68:18-21. 2007
    ....
  23. doi request reprint Osteoprotegerin is higher in peripheral arterial disease regardless of glycaemic status
    Eoin P O'Sullivan
    Department of Diabetes, Royal College of Surgeons in Ireland Medical School, Beaumont Hospital, and Centre for Preventive Medicine, School of Health and Human Performance, Dublin City University, Dublin 9, Ireland
    Thromb Res 126:e423-7. 2010
    ..The recently identified Osteoprotegerin(OPG)/RANKL/TRAIL pathway has been implicated in vascular calcification, but data on levels in PAD and effect of co-existent DM are lacking...
  24. doi request reprint Clinical review: Disorders of water homeostasis in neurosurgical patients
    Mark J Hannon
    Academic Department of Endocrinology, Beaumont Hospital and Royal College of Surgeons in Ireland Medical School, Dublin 9, Ireland
    J Clin Endocrinol Metab 97:1423-33. 2012
    ..They are most commonly seen after subarachnoid hemorrhage, traumatic brain injury, with intracranial tumors, and after pituitary surgery...
  25. doi request reprint The prevalence of adrenal incidentaloma in routine clinical practice
    Colin Davenport
    Department of Diabetes and Endocrinology, Royal College of Surgeons in Ireland Medical School, Beaumont Hospital, Dublin 9, Ireland
    Endocrine 40:80-3. 2011
    ..Twenty-two were diagnosed by CT abdomen (22/2,227) and 12 by CT thorax (12/1,478), a prevalence of 0.98 and 0.81% with CT abdomen and thorax, respectively, for AI in routine clinical practice...
  26. ncbi request reprint Attenuation of vasopressin-induced antidiuresis in poorly controlled type 2 diabetes
    Amar Agha
    Academic Department of Endocrinology, Endocrine Unit, Beaumont Hospital, Dublin 9, Ireland
    Am J Physiol Endocrinol Metab 287:E1100-6. 2004
    ..Under conditions of chronic hyperglycemia, these abnormalities may significantly contribute to the development of dehydration in PCDS...
  27. doi request reprint Osteoprotegerin and biomarkers of vascular inflammation in type 2 diabetes
    Eoin P O'Sullivan
    Department of Diabetes, Royal College of Surgeons in Ireland Medical School, Beaumont Hospital, Dublin, Ireland
    Diabetes Metab Res Rev 26:496-502. 2010
    ....
  28. doi request reprint Late recovery of cranial diabetes insipidus following pituitary surgery
    Nigel Glynn
    Division of Neuroendocrinology, Beaumont Hospital and Royal College of Surgeons in Ireland Medical School, Dublin, Ireland
    Horm Res Paediatr 80:217-20. 2013
    ..Diabetes insipidus (DI) is common following surgery for a pituitary/sellar lesion. Postoperative DI persisting beyond a few weeks is usually regarded as permanent, requiring lifelong desmopressin therapy...
  29. doi request reprint Unexpected clinical course during treatment of a TSH-secreting pituitary adenoma
    Nigel Glynn
    Division of Neuroendocrinology, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
    Endocr Pract 19:e88-91. 2013
    ..To report the rare occurrence of a patient with thyrotropinoma that transitioned into a secretory thyro-somatotroph adenoma during medical treatment with somatostatin analogue...
  30. doi request reprint Clinical insights into the safety and utility of the insulin tolerance test (ITT) in the assessment of the hypothalamo-pituitary-adrenal axis
    Francis M Finucane
    Academic Department of Endocrinology, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
    Clin Endocrinol (Oxf) 69:603-7. 2008
    ..Whether basal cortisol concentration can reliably predict an adequate adrenal response to hypoglycaemia remains to be determined...
  31. ncbi request reprint Hypopituitarism following traumatic brain injury (TBI)
    Amar Agha
    Divisions of Endocrinology and Neurosurgery, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
    Br J Neurosurg 21:210-6. 2007
    ....
  32. ncbi request reprint Unmasking of central hypothyroidism following growth hormone replacement in adult hypopituitary patients
    Amar Agha
    William Harvey Research Institute, Queen Mary University of London, London, UK
    Clin Endocrinol (Oxf) 66:72-7. 2007
    ..The effect of GH replacement on thyroid function in hypopituitary patients has hitherto been studied in small groups of children and adults with conflicting results...
  33. doi request reprint Central pontine myelinolysis complicating treatment of the hyperglycaemic hyperosmolar state
    Grainne O'Malley
    Division of Endocrinology and Diabetes, Beaumont Hospital, Dublin, Ireland
    Ann Clin Biochem 45:440-3. 2008
    ....
  34. doi request reprint Which patient requires neuroendocrine assessment following traumatic brain injury, when and how?
    Nigel Glynn
    Division of Neuro endocrinology, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
    Clin Endocrinol (Oxf) 78:17-20. 2013
    ..Patients who suffer milder forms of TBI should also be considered for endocrine evaluation if they exhibit any clinical features of pituitary hormone deficiencies...
  35. ncbi request reprint High risk of hypogonadism after traumatic brain injury: clinical implications
    Amar Agha
    Academic Division of Endocrinology and Diabetes, Beaumont Hospital and RCSI Medical School, Dublin, Ireland
    Pituitary 8:245-9. 2005
    ....
  36. ncbi request reprint The role of menin in parathyroid tumorigenesis
    Colin Davenport
    Academic Department of Endocrinology, Beaumont Hospital and Royal College of Surgeons in Ireland Medical School, Beaumont Road, Dublin 9, Ireland
    Adv Exp Med Biol 668:79-86. 2009
    ..This chapter aims to review the role of menin in primary hyperparathyroidism and parathyroid hormone-regulation, including the influences of MEN1 gene mutations on parathyroid cell proliferation, differentiation and tumorigenesis...
  37. pmc Diagnosing growth hormone deficiency in adults
    Nigel Glynn
    Department of Endocrinology, Beaumont Hospital, RCSI Medical School, Dublin 9, Ireland
    Int J Endocrinol 2012:972617. 2012
    ..In addition, there is considerable analytical variation in the biochemical measurements of GH and IGF-1 which must be considered before making a diagnosis of GHD in adulthood...
  38. ncbi request reprint A case of Resistance to Thyroid Hormone without mutation in the thyroid hormone receptor beta
    J H McDermott
    Depts of Endocrinology, Royal College of Surgeons in Ireland, Connolly Hospital, Blanchardstown, Dublin, Ireland
    Ir J Med Sci 174:60-4. 2005
    ..Resistance to Thyroid Hormone (RTH) is a condition caused by tissue hyposensitivity to the effects of circulating thyroid hormone, and may be misdiagnosed as hyperthyroidism...
  39. doi request reprint An intensive nurse-led, multi-interventional clinic is more successful in achieving vascular risk reduction targets than standard diabetes care
    J MacMahon Tone
    Academic Department of Diabetes and Endocrinology, Beaumont Hospital RCSI Medical School, Beaumont Road, Dublin 9, Ireland
    Ir J Med Sci 178:179-86. 2009
    ..The aim of this research was to determine whether an intensive, nurse-led clinic could achieve recommended vascular risk reduction targets in patients with type 2 diabetes as compared to standard diabetes management...
  40. ncbi request reprint Neuroendocrine disorders after traumatic brain injury
    L A Behan
    Academic Department of Endocrinology, Beaumont Hospital and RCSI Medical School, Dublin, Ireland
    J Neurol Neurosurg Psychiatry 79:753-9. 2008
    ....
  41. ncbi request reprint Hypothalamopituitary dysfunction following traumatic brain injury and aneurysmal subarachnoid hemorrhage: a systematic review
    Harald Jorn Schneider
    Neuroendocrinology Group, Max Planck Institute of Psychiatry, Munich, Germany
    JAMA 298:1429-38. 2007
    ..This sequela is a potentially serious but treatable complication of brain injury...
  42. ncbi request reprint The long-term predictive accuracy of the short synacthen (corticotropin) stimulation test for assessment of the hypothalamic-pituitary-adrenal axis
    Amar Agha
    Division of Medical Sciences, University of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, United Kingdom
    J Clin Endocrinol Metab 91:43-7. 2006
    ..The high-dose short Synacthen (corticotropin) test (SST) is widely used to investigate suspected secondary adrenal insufficiency, but concern remains about falsely reassuring results...
  43. ncbi request reprint Aneurysmal subarachnoid hemorrhage
    Mark Sherlock
    N Engl J Med 354:1755-7; author reply 1755-7. 2006