Rakesh Aggarwal

Summary

Publications

  1. ncbi T-cell epitope mapping of ORF2 and ORF3 proteins of human hepatitis E virus
    R Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Viral Hepat 14:283-92. 2007
  2. ncbi Diagnosis of hepatitis E
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    Nat Rev Gastroenterol Hepatol 10:24-33. 2013
  3. ncbi Effect of maternal education on choice of location for delivery among Indian women
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
    Natl Med J India 24:328-34. 2011
  4. ncbi Plasma peptidome profiling of acute hepatitis E patients by MALDI-TOF/TOF
    Shikha Taneja
    Virology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India
    Proteome Sci 9:5. 2011
  5. ncbi Epidemiology of hepatitis E: current status
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 24:1484-93. 2009
  6. ncbi Hepatitis E: Historical, contemporary and future perspectives
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 26:72-82. 2011
  7. ncbi Clinical presentation of hepatitis E
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Virus Res 161:15-22. 2011
  8. ncbi A comparison of online versus on-site training in health research methodology: a randomized study
    Rakesh Aggarwal
    Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    BMC Med Educ 11:37. 2011
  9. ncbi Hepatitis E
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Hepatology 54:2218-26. 2011
  10. ncbi Hepatitis B virus genotype A is more often associated with severe liver disease in northern India than is genotype D
    Ashish Kumar
    Departments of Gastroenterology and Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow-226 014, India
    Indian J Gastroenterol 24:19-22. 2005

Collaborators

Detail Information

Publications74

  1. ncbi T-cell epitope mapping of ORF2 and ORF3 proteins of human hepatitis E virus
    R Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Viral Hepat 14:283-92. 2007
    ..These data on mapping of T-cell epitopes in HEV proteins may prove useful for designing HEV vaccines and for studying the immunopathogenesis of hepatitis E...
  2. ncbi Diagnosis of hepatitis E
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    Nat Rev Gastroenterol Hepatol 10:24-33. 2013
    ..Improved validation of existing anti-HEV antibody assays or development of new assays with superior performance characteristics is urgently needed...
  3. ncbi Effect of maternal education on choice of location for delivery among Indian women
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
    Natl Med J India 24:328-34. 2011
    ..However, in India, a large proportion of deliveries take place outside health facilities. We studied the effect of maternal education on the choice of location for delivery in the Indian population...
  4. ncbi Plasma peptidome profiling of acute hepatitis E patients by MALDI-TOF/TOF
    Shikha Taneja
    Virology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India
    Proteome Sci 9:5. 2011
    ..abstract:..
  5. ncbi Epidemiology of hepatitis E: current status
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 24:1484-93. 2009
    ..Our understanding of hepatitis E epidemiology has undergone major changes in recent years, and the future may hold even more surprises...
  6. ncbi Hepatitis E: Historical, contemporary and future perspectives
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 26:72-82. 2011
    ..These vaccines should be of particular use in groups that are at high risk of HEV infection and/or of poor outcome...
  7. ncbi Clinical presentation of hepatitis E
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Virus Res 161:15-22. 2011
    ..The pathogenesis of these manifestations remains unclear...
  8. ncbi A comparison of online versus on-site training in health research methodology: a randomized study
    Rakesh Aggarwal
    Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    BMC Med Educ 11:37. 2011
    ..Our objective was to determine whether on-line courses in Biostatistics and Research Ethics could achieve similar improvements in knowledge, as traditional on-site, classroom-based courses...
  9. ncbi Hepatitis E
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Hepatology 54:2218-26. 2011
    ..Two recombinant protein vaccines have undergone successful human trials, but are not yet commercially available. Recent development of cell-culture methods for HEV should allow a better understanding of this enigmatic agent...
  10. ncbi Hepatitis B virus genotype A is more often associated with severe liver disease in northern India than is genotype D
    Ashish Kumar
    Departments of Gastroenterology and Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow-226 014, India
    Indian J Gastroenterol 24:19-22. 2005
    ..Genotype A was more often associated with ALT elevation, HBeAg positivity, absence of anti-HBe and, among those aged 25 years and above, cirrhosis of liver, than was genotype D...
  11. ncbi Adaptive immune responses during acute uncomplicated and fulminant hepatitis E
    Ratika Srivastava
    Department of Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 26:306-11. 2011
    ..We therefore studied adaptive immune responses to HEV antigens in patients with hepatitis E of varying disease severity and healthy controls...
  12. ncbi Hepatitis E virus is responsible for decompensation of chronic liver disease in an endemic region
    Arvind Kumar
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226 014
    Indian J Gastroenterol 23:59-62. 2004
    ..Twelve patients survived, as compared to 9 of 18 patients without evidence of recent HEV infection (p<0.01). CONCLUSION: HEV infection is a frequent cause of decompensation in patients with liver cirrhosis in HEV-endemic regions...
  13. ncbi Spectrum of malabsorption syndrome among adults & factors differentiating celiac disease & tropical malabsorption
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Indian J Med Res 136:451-9. 2012
    ..This study was undertaken to investigate the spectrum of MAS among Indian adults and to find out the features that may help to differentiate between TM and celiac disease...
  14. ncbi Evidence of hepatitis E virus exposure among seronegative healthy residents of an endemic area
    Mohammad Mushtaq Husain
    Department of Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Intervirology 54:139-43. 2011
    ..Detection of serum anti-HEV IgG has traditionally been used to determine prior exposure to this virus. We studied HEV-specific recall immune responses in healthy subjects with and without detectable anti-HEV IgG...
  15. ncbi Clinical features and predictors of outcome in acute hepatitis A and hepatitis E virus hepatitis on cirrhosis
    Yellapu Radha Krishna
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Liver Int 29:392-8. 2009
    ..Our study aimed to evaluate the clinical profile and predictors of 3-month mortality in patients with this distinctive form of liver failure...
  16. ncbi Tropical sprue is associated with contamination of small bowel with aerobic bacteria and reversible prolongation of orocecal transit time
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 18:540-7. 2003
    ..In tropical sprue (TS), response to antibiotics may suggest a role for bacterial contamination of the small bowel, which is known in diseases with prolonged orocecal transit time (OCTT)...
  17. ncbi Etiological spectrum of sporadic malabsorption syndrome in northern Indian adults at a tertiary hospital
    Piyush Ranjan
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Indian J Gastroenterol 23:94-8. 2004
    ..CONCLUSIONS: Tropical sprue, celiac disease and Crohn's disease are common causes of MAS in Indian adults. Inappropriate anti-tubercular treatment is common in them and needs to be discouraged...
  18. ncbi Occult hepatitis B virus infection as a cause of cirrhosis of liver in a region with intermediate endemicity
    Neeti Agarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226 014
    Indian J Gastroenterol 22:127-31. 2003
    ..HBV DNA testing in serum and liver can help in establishing HBV infection as etiology, either alone or in addition to another cause...
  19. ncbi Role of IgG anti-beta-lactoglobulin antibody in the diagnosis of cow's milk protein intolerance in India
    Ujjal Poddar
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Indian J Gastroenterol 27:190-4. 2008
    ..Little is known about cow's milk protein intolerance (CMPI) in India. This study was aimed at finding CMPI cases and determining the role of IgG anti-beta-lactoglobulin antibody in the diagnosis of this condition in India...
  20. ncbi Assessment of cost-effectiveness of universal hepatitis B immunization in a low-income country with intermediate endemicity using a Markov model
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    J Hepatol 38:215-22. 2003
    ..We performed a cost-effectiveness analysis of universal childhood HB immunization in such countries using India as an example, since available data on this aspect are limited...
  21. ncbi Factor V Leiden and prothrombin gene G20210A mutations are uncommon in portal vein thrombosis in India
    Sanjay Sharma
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226 014, India
    Indian J Gastroenterol 25:236-9. 2006
    ..The cause of thrombosis in these patients remains unclear. We studied the frequency of mutations in genes for coagulation factors V and II (prothrombin) in 61 Indian patients with PVT and 49 healthy control subjects...
  22. ncbi Cellular immune responses in acute hepatitis E virus infection to the viral open reading frame 2 protein
    Ruchi Srivastava
    Department of Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Viral Immunol 20:56-65. 2007
    ..Further, the limited immune reactivity we detected in peripheral blood cells may be related to the sequestration of immune events to the intrahepatic compartment, which is the major disease site...
  23. ncbi Profile of liver involvement in dengue virus infection
    Srivenu Itha
    Sanjay Gandhi Postgraduate Institute of Medical Sciences, Rae Bareli Road, Lucknow 226014, Uttar Pradesh, India
    Natl Med J India 18:127-30. 2005
    ..CONCLUSION: Our data show that liver injury is common in adult patients with dengue infection. Further studies are needed to determine the mechanism of liver injury in this disease...
  24. ncbi Hepatitis B virus carriers; natural course, diagnostic approach and treatment
    Piyush Ranjan
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Trop Gastroenterol 26:58-65. 2005
  25. ncbi Does co-infection with multiple viruses adversely influence the course and outcome of sporadic acute viral hepatitis in children?
    Arvind Kumar
    Department of Gastroenterology Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 21:1533-7. 2006
    ..This study looked at the frequency of co-infection with multiple hepatotropic viruses and the effect of such infection on the course and outcome of acute sporadic viral hepatitis (AVH) and fulminant hepatic failure (FHF) in children...
  26. ncbi Low frequency of factor V Leiden and prothrombin G20210A mutations in patients with hepatic venous outflow tract obstruction in northern India: a case-control study
    Sirish I Kumar
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Indian J Gastroenterol 24:211-5. 2005
    ..We studied the prevalence of these mutations among patients with HVOTO in northern India in comparison with healthy population...
  27. ncbi Immunological alterations in pregnant women with acute hepatitis E
    Rekha Pal
    Department of Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 20:1094-101. 2005
    ..CONCLUSION: These results show the existence of a Th2 bias in pregnant women with acute hepatitis E. The role of this Th2 bias in the greater severity of hepatitis E among pregnant women needs further investigation...
  28. ncbi Antibody testing in Indian children with celiac disease
    Surender Kumar Yachha
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226 014, India
    Indian J Gastroenterol 25:132-5. 2006
    ....
  29. ncbi Histological and immunohistochemical features in fatal acute fulminant hepatitis E
    Vinita Agrawal
    Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
    Indian J Pathol Microbiol 55:22-7. 2012
    ..Hepatitis E is being increasingly recognized as an emerging infection in developed countries. Data on histological findings and nature of inflammatory cell infiltrate in liver in this disease are quite sparse...
  30. ncbi Treatment of chronic hepatitis B with interferon-alpha: cost-effectiveness in developing countries
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, Uttar Pradesh, India
    Natl Med J India 15:320-7. 2002
    ..Treatment with interferon-alpha (IFN) has been shown to be cost-effective in developed countries. However, cost-effectiveness In developing countries such as India has not been studied...
  31. ncbi Presence of hepatitis E virus in sewage in Northern India: frequency and seasonal pattern
    Sirish Kumar Ippagunta
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Med Virol 79:1827-31. 2007
    ..The study suggests that HEV infection and fecal viral excretion may be common in HEV-endemic regions throughout the year even during non-epidemic periods...
  32. ncbi Prediction of large esophageal varices in patients with cirrhosis of the liver using clinical, laboratory and imaging parameters
    Sanjay Kumar Sharma
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 22:1909-15. 2007
    ..This approach leads to unnecessary UGIE in those without LEVx. We tried to identify clinical, laboratory and imaging parameters that may predict the presence of LEVx and help select patients for UGIE...
  33. ncbi Effect of a gluten-free diet on growth and small-bowel histology in children with celiac disease in India
    Surender K Yachha
    Department of Gastroenterology Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 22:1300-5. 2007
    ..Follow-up studies on growth and histological recovery of children with celiac disease (CD) while on a gluten-free diet (GFD) are lacking from Asia. We therefore assessed the effects of this diet...
  34. ncbi A boost to hepatitis B vaccine: no need for boosters
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh
    Natl Med J India 18:313-4. 2005
  35. ncbi Severe ulcerative colitis: prospective study of parameters determining outcome
    Sanjay Kumar
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 19:1247-52. 2004
    ..CONCLUSION: It may be possible to predict the failure of medical treatment in exacerbations of UC using a scoring system based on clinical parameters and simple laboratory tests...
  36. ncbi Role of travel as a risk factor for hepatitis E virus infection in a disease-endemic area
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Indian J Gastroenterol 21:14-8. 2002
    ..We undertook epidemiologic and laboratory studies during an epidemic of acute hepatitis in Sindri town, in District Dhanbad, Bihar in 1998...
  37. ncbi Preventing and treating hepatitis B infection
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226 014, India
    BMJ 329:1080-6. 2004
  38. ncbi Abernethy malformation with portal vein aneurysm
    Atin Kumar
    Department of Radiology, All India Institute of Medical Sciences, New Delhi, India
    Diagn Interv Radiol 14:143-6. 2008
    ..Etiology, clinical significance, and management strategies with regard to these abnormalities are discussed...
  39. ncbi Vestibular schwannoma: role of conservative management
    R Suryanarayanan
    Department of Otolaryngology, Manchester Royal Infirmary and Hope Hospital, Salford, UK
    J Laryngol Otol 124:251-7. 2010
    ..To assess the outcome of conservative management of vestibular schwannoma...
  40. ncbi Validation of video-based skill assessment in carotid artery stenting
    I Van Herzeele
    Department of Thoracic and Vascular Surgery, Ghent University Hospital, Gent, Belgium
    Eur J Vasc Endovasc Surg 38:1-9. 2009
    ..To develop weighted error-based, generic and procedure-specific rating scales, to validate these scales for video-based assessment during virtual carotid artery stent (CAS) procedures and correlate them with simulator-derived metrics...
  41. ncbi Experienced endovascular interventionalists objectively improve their skills by attending carotid artery stent training courses
    I Van Herzeele
    Department of Biosurgery and Surgical Technology, Imperial College London, UK Regional Vascular Unit, St Mary s Hospital, London, UK
    Eur J Vasc Endovasc Surg 35:541-50. 2008
    ..Carotid artery stenting (CAS) is an advanced endovascular intervention with a steep learning curve. Virtual reality (VR) simulation has been proposed as a means to train and objectively assess technical performance...
  42. ncbi Training with simulation versus operative room attendance
    L M Desender
    Department of Thoracic and Vascular Surgery, University Hospital Ghent, Ghent, Belgium
    J Cardiovasc Surg (Torino) 52:17-37. 2011
    ..This article reviews the evidence and the limitations for this adjunctive tool, the implementation in current training programmes and future applications to maintain the highest standards of care for treatment of vascular disease...
  43. ncbi Evidence for activation of cellular immune responses in patients with acute hepatitis E
    Sita Naik
    Department of Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Indian J Gastroenterol 21:149-52. 2002
    ..We looked for evidence of lymphocyte sensitization to HEV peptides in patients with acute HEV infection...
  44. ncbi HFE, hepcidin and ferroportin gene mutations are not present in Indian patients with primary haemochromatosis
    Priyanka Shukla
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
    Natl Med J India 19:20-3. 2006
    ..CONCLUSION: Our patients with primary haemochromatosis lacked mutations in the HFE, hepcidin and ferroportin genes. Further genetic analysis may help identify novel mutations responsible for primary haemochromatosis in these patients...
  45. ncbi Superior sagittal sinus thrombosis and Budd-Chiari syndrome due to paroxysmal nocturnal hemoglobinuria managed with transjugular intrahepatic portosystemic shunt: a case report
    Abhinav Sharma
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    Trop Gastroenterol 26:146-8. 2005
    ..For Budd-Chiari syndrome in patients with underlying PNH, transjugular intrahepatic portosystemic shunt may be a good option but caution is needed to prevent stent occlusion...
  46. ncbi Alterations in natural killer cells and natural killer T cells during acute viral hepatitis E
    R Srivastava
    Department of Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Viral Hepat 15:910-6. 2008
    ..During convalescence, all the parameters normalized. In conclusion, reversible alterations in NK and NKT cell number and activation status during acute hepatitis E suggest a role of these cells in the pathogenesis of this disease...
  47. ncbi Non-organ-specific autoantibodies in Indian patients with chronic liver disease
    Sunilbaran Daschakraborty
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226 014, India
    Indian J Gastroenterol 31:237-42. 2012
    ..However, various autoantibodies are often detectable in patients with CLD due to other causes too. Since data on autoantibody prevalence in Indian patients with CLD are limited, we decided to undertake the current study...
  48. ncbi Hepatitis E vaccine
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences SGPGIMS, Rae Bareilly Road, Lucknow, 226 014, India
    Hepatol Int 2:308-15. 2008
    ..However, significant progress has been made in developing and testing recombinant subunit vaccines based on the viral capsid protein. This review summarizes these efforts...
  49. ncbi Recurrent duodenal ulcer haemorrhage: a pharmacoeconomic comparison of various management strategies
    Uday Chand Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, India
    Expert Opin Pharmacother 4:1593-603. 2003
    ..Prevention of recurrence is, therefore, an important goal. Eradication of Helicobacter pylori or maintenance treatment with a proton pump inhibitor (PPI) may reduce recurrent DU bleeding. Economic comparison of these options is sparse...
  50. ncbi Piperacillin induced bone marrow suppression: a case report
    Ashish Kumar
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    BMC Clin Pharmacol 3:2. 2003
    ..Piperacillin (and piperacillin/tazobactam) is a commonly prescribed antibiotic and is generally considered safe. We report a case of piperacillin induced bone marrow suppression...
  51. ncbi Hepatitis A vaccine versus immunoglobulin for post-exposure prophylaxis
    Anshu Srivastava
    Department of Paediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh
    Natl Med J India 20:302-3. 2007
  52. ncbi Strongyloides stercoralis infestation associated with septicemia due to intestinal transmural migration of bacteria
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, India
    J Gastroenterol Hepatol 17:1331-3. 2002
    ..This supports the hypothesis of migration of bacteria from the intestinal lumen as a cause of septicemia in patients with fulminant S. stercoralis infestation...
  53. ncbi Plasmodium falciparum and hepatitis E virus co-infection in fulminant hepatic failure
    U C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Indian J Gastroenterol 20:111. 2001
    ..Peripheral smear was positive for Plasmodium falciparum, and IgM anti-HEV was positive. She died despite antimalarial drugs and supportive management. Postmortem liver tissue showed changes suggestive of acute viral hepatitis...
  54. ncbi A serological study of intrafamilial spread from patients with sporadic hepatitis E virus infection
    S K Somani
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow-226 014, India
    J Viral Hepat 10:446-9. 2003
    ..This suggests that person-to-person transmission is uncommon in sporadic hepatitis E...
  55. ncbi Hepatitis E virus RNA detection in serum and feces specimens with the use of microspin columns
    R Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Virol Methods 74:209-13. 1998
    ..Use of this method may allow better assessment of viremia and fecal excretion in patients and experimental animals infected with HEV...
  56. ncbi Hepatitis E virus infection among animals in northern India: an unlikely source of human disease
    P Shukla
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Viral Hepat 14:310-7. 2007
    ..However, the swine HEV in India differs genetically from human HEV isolates, indicating that pigs may not play an important role in the spread of human hepatitis E in endemic regions...
  57. ncbi High frequency of hepatitis B virus infection in patients with beta-thalassemia receiving multiple transfusions
    H Singh
    Department of Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Vox Sang 84:292-9. 2003
    ..The frequency of infection was similar in vaccine responders and non-responders. A number of mutations were observed in the S gene, which could have implications for viral replication as well as virus-host cell interaction...
  58. ncbi A large waterborne viral hepatitis E epidemic in Kanpur, India
    S R Naik
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Bull World Health Organ 70:597-604. 1992
    ..The first peak was probably caused by faecal contamination of river water, indicated by water analysis data, and the second, by inadequate chlorination of water in a reservoir. There was no evidence of secondary intrafamilial spread...
  59. ncbi Virtual reality simulation training can improve inexperienced surgeons' endovascular skills
    R Aggarwal
    Department of Biosurgery and Surgical Technology, Imperial College London, London, UK
    Eur J Vasc Endovasc Surg 31:588-93. 2006
    ..The aim of this study was to evaluate virtual reality (VR) simulation for endovascular training of surgeons inexperienced in this technique...
  60. ncbi Identification of skills common to renal and iliac endovascular procedures performed on a virtual reality simulator
    S K Neequaye
    Department of Biosurgery and Surgical Technology, Imperial College, London, UK
    Eur J Vasc Endovasc Surg 33:525-32. 2007
    ..The aim of this study was to determine the nature of skills acquisition on the renal and iliac modules of a commercially-available VR simulator...
  61. ncbi Systematic review of randomized controlled trials on the effectiveness of virtual reality training for laparoscopic surgery
    K Gurusamy
    Hepatopancreatobiliary and Liver Transplant Surgery, University Department of Surgery, Royal Free and University College School of Medicine, University College London and Royal Free Hospital NHS Trust, London NW32QG, UK
    Br J Surg 95:1088-97. 2008
    ..The aim of this review was to determine whether virtual reality (VR) training can supplement and/or replace conventional laparoscopic training in surgical trainees with limited or no laparoscopic experience...
  62. ncbi Objective assessment of gynecologic laparoscopic skills using the LapSimGyn virtual reality simulator
    C R Larsen
    Department of Gynecology and Obstetrics, The Juliane Marie Centre (for Children, woman, and Reproduction, Copenhagen University Hospital, Blegdamsvej 3, Rigshospitalet, DK- 2100, Denmark
    Surg Endosc 20:1460-6. 2006
    ..LapSimGyn also seems to be flexible and widely accepted by the users...
  63. ncbi The simulated operating theatre: comprehensive training for surgical teams
    R Aggarwal
    Department of Surgical Oncology and Technology, Imperial College London, 10th Floor, QEQM Building, St Mary s Hospital, Praed Street, London, W2 1NY UK
    Qual Saf Health Care 13:i27-32. 2004
    ..The effect of external influences such as distractions, new technology, or a crisis scenario can also be defined, with the ultimate aim of reducing the number of adverse events arising in the real operating room...
  64. ncbi Skills training in telerobotic surgery
    J Hance
    Department of Surgical Oncology and Technology, Imperial College, London, UK
    Int J Med Robot 1:7-12. 2005
    ..Only when the standard of practice is firmly established, should the proliferation of robotic practitioners be encouraged thus ensuring patient safety is not compromised...
  65. ncbi Robotic prostatectomy: the first UK experience
    E K Mayer
    Imperial Robotic Urological Surgery Group, Department of Urology, St Mary's Hospital, London, UK
    Int J Med Robot 2:321-8. 2006
    ..The structured approach used in this setting demonstrates that urological surgeons of varying laparoscopic experience can acquire the skills necessary to competently perform laparoscopic radical prostatectomy...
  66. ncbi Motion tracking systems for assessment of surgical skill
    R Aggarwal
    Surg Endosc 21:339. 2007
  67. ncbi Virtual reality simulation training can improve technical skills during laparoscopic salpingectomy for ectopic pregnancy
    R Aggarwal
    Department of Biosurgery and Surgical Technology, Imperial College London, London, UK
    BJOG 113:1382-7. 2006
    ..To assess the first commercially available virtual reality (VR) simulator to incorporate procedural modules for training of inexperienced gynaecological surgeons to perform laparoscopic salpingectomy for ectopic pregnancy...
  68. ncbi Global epidemiology and medical aspects of hepatitis E
    K Krawczynski
    Division of Viral Hepatitis, NCID, Centers for Disease Control and Prevention Atlanta, GA 30333, USA
    Forum (Genova) 11:166-79. 2001
    ..Recombinant vaccines are being developed that may be particularly useful for travellers to the disease-endemic areas and for pregnant women...
  69. ncbi Consensus guidelines for validation of virtual reality surgical simulators
    F J Carter
    The Cuschieri Skills Centre, Ninewells Hospital, University of Dundee, Dundee, Scotland
    Surg Endosc 19:1523-32. 2005
    ..The work group intends to update these consensus guidelines on a regular basis, with the resulting article available on the EAES website (http://www.eaes-eur.org )...
  70. ncbi Training in the operating theatre: is it safe?
    R Aggarwal
    Thorax 61:278-9. 2006
  71. ncbi Laparoscopic skills training and assessment
    R Aggarwal
    Department of Surgical Oncology and Technology, Imperial College, London, UK
    Br J Surg 91:1549-58. 2004
    ..This article reviews the tools currently available for training and assessment in laparoscopic surgery...
  72. ncbi Validation of orthopaedic bench models for trauma surgery
    J J H Leong
    St Mary s Hospital, London, England
    J Bone Joint Surg Br 90:958-65. 2008
    ..The availability of valid objective tools of assessment of surgical skills allows further studies into improving methods of training...
  73. ncbi Endovascular simulation-based training
    R Aggarwal
    Surgeon 6:196-7. 2008
  74. ncbi Technical skills examination for general surgical trainees
    V Datta
    Department of Surgical Oncology and Technology, 10th Floor, Queen Elizabeth the Queen Mother Building, St Mary s Hospital, London W2 1NY, UK
    Br J Surg 93:1139-46. 2006
    ..The technical skills of surgical trainees are difficult to assess and compare objectively. This study involved a structured, multistation, technical skills examination that enables the stratification of surgical trainees...