Andrew Adey

Summary

Publications

  1. pmc Rapid, low-input, low-bias construction of shotgun fragment libraries by high-density in vitro transposition
    Andrew Adey
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    Genome Biol 11:R119. 2010
  2. ncbi request reprint Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions
    Joshua N Burton
    Department of Genome Sciences, University of Washington, Seattle, Washington, USA
    Nat Biotechnol 31:1119-25. 2013
  3. pmc The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line
    Andrew Adey
    Department of Genome Sciences, University of Washington, Seattle, Washington 98115, USA
    Nature 500:207-11. 2013
  4. pmc Capturing native long-range contiguity by in situ library construction and optical sequencing
    Jerrod J Schwartz
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 109:18749-54. 2012
  5. pmc Ultra-low-input, tagmentation-based whole-genome bisulfite sequencing
    Andrew Adey
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    Genome Res 22:1139-43. 2012
  6. pmc megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
    Sandrine Boissel
    Molecular and Cellular Biology Program, University of Washington, Seattle, WA 98195, USA, Center for Immunity and Immunotherapies, Seattle Children s Research Institute, Seattle, WA 98101, USA, Pregenen, Inc, Seattle, WA 98103, USA, Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA, CELLECTIS S A, Paris, 75013, France, Division of Basic Sciences, Fred Hutch Cancer Research Center, Seattle, WA 98109, USA, Department of Biochemistry, University of Washington, Seattle, WA 98195, USA, Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA and Department of Immunology, University of Washington, Seattle, WA 98195, USA
    Nucleic Acids Res 42:2591-601. 2014
  7. pmc Haplotype-resolved genome sequencing of a Gujarati Indian individual
    Jacob O Kitzman
    Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington, USA
    Nat Biotechnol 29:59-63. 2011

Collaborators

Detail Information

Publications7

  1. pmc Rapid, low-input, low-bias construction of shotgun fragment libraries by high-density in vitro transposition
    Andrew Adey
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    Genome Biol 11:R119. 2010
    ..We also extend its capabilities by developing protocols for sub-nanogram library construction, exome capture from 50 ng of input DNA, PCR-free and colony PCR library construction, and 96-plex sample indexing...
  2. ncbi request reprint Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions
    Joshua N Burton
    Department of Genome Sciences, University of Washington, Seattle, Washington, USA
    Nat Biotechnol 31:1119-25. 2013
    ..Hi-C data can also be used to validate chromosomal translocations in cancer genomes...
  3. pmc The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line
    Andrew Adey
    Department of Genome Sciences, University of Washington, Seattle, Washington 98115, USA
    Nature 500:207-11. 2013
    ..These data provide an extensively phased, high-quality reference genome for past and future experiments relying on HeLa, and demonstrate the value of haplotype resolution for characterizing cancer genomes and epigenomes...
  4. pmc Capturing native long-range contiguity by in situ library construction and optical sequencing
    Jerrod J Schwartz
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 109:18749-54. 2012
    ....
  5. pmc Ultra-low-input, tagmentation-based whole-genome bisulfite sequencing
    Andrew Adey
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    Genome Res 22:1139-43. 2012
    ..We demonstrate Tn5mC-seq by sequencing the methylome of a human lymphoblastoid cell line to ∼8.6× high-quality coverage of each strand...
  6. pmc megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
    Sandrine Boissel
    Molecular and Cellular Biology Program, University of Washington, Seattle, WA 98195, USA, Center for Immunity and Immunotherapies, Seattle Children s Research Institute, Seattle, WA 98101, USA, Pregenen, Inc, Seattle, WA 98103, USA, Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA, CELLECTIS S A, Paris, 75013, France, Division of Basic Sciences, Fred Hutch Cancer Research Center, Seattle, WA 98109, USA, Department of Biochemistry, University of Washington, Seattle, WA 98195, USA, Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA and Department of Immunology, University of Washington, Seattle, WA 98195, USA
    Nucleic Acids Res 42:2591-601. 2014
    ..This architecture allows the generation of extremely active and hyper-specific compact nucleases that are compatible with all current viral and nonviral cell delivery methods. ..
  7. pmc Haplotype-resolved genome sequencing of a Gujarati Indian individual
    Jacob O Kitzman
    Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington, USA
    Nat Biotechnol 29:59-63. 2011
    ..This method also facilitates the analysis of structural variation, for example, to anchor novel insertions to specific locations and haplotypes...