Sergazy M Adekenov

Summary

Publications

  1. Khlebnikov A, Schepetkin I, Kishkentaeva A, Shaimerdenova Z, Atazhanova G, Adekenov S, et al. Inhibition of T Cell Receptor Activation by Semi-Synthetic Sesquiterpene Lactone Derivatives and Molecular Modeling of Their Interaction with Glutathione and Tyrosine Kinase ZAP-70. Molecules. 2019;24: pubmed publisher
    ..We suggest that natural and/or semi-synthetic SLs with an α -methylene- γ -lactone moiety can specifically target GSH and the kinase site of ZAP-70 and inhibit the initial phases of TCR activation. ..
  2. Temirgaziyev B, Kučáková K, Baizhigit Y, Jurášek M, Dzubak P, Hajduch M, et al. Bioavailability and Stuctural Study of 20-Hydroxyecdysone Complexes with Cyclodextrins. Steroids. 2018;: pubmed publisher
    ..Ecdysterone-β-cyclodextrin complexes exhibit 100 times higher solubility in water than the parent compound. ..