Michel Adamina

Summary

Publications

  1. doi request reprint Contemporary perioperative care strategies
    M Adamina
    Department of Surgery, Kantonsspital St Gallen, St Gallen, Switzerland Institute for Surgical Research and Hospital Management, University of Basel, Basel, Switzerland
    Br J Surg 100:38-54. 2013
  2. ncbi request reprint Laparoscopic complete mesocolic excision for right colon cancer
    Michel Adamina
    Division of Colorectal Surgery, University Hospitals Case Medical Center, Cleveland, OH, USA
    Surg Endosc 26:2976-80. 2012
  3. ncbi request reprint Heterologous prime-boost immunotherapy of melanoma patients with Influenza virosomes, and recombinant Vaccinia virus encoding 5 melanoma epitopes and 3 co-stimulatory molecules. A multi-centre phase I/II open labeled clinical trial
    Michel Adamina
    Institute for Surgical Research and Hospital Management, Department of Surgery, University of Basel, Hebelstrasse 20, 4031 Basel, Switzerland
    Contemp Clin Trials 29:165-81. 2008
  4. doi request reprint Bayesian statistics in oncology: a guide for the clinical investigator
    Michel Adamina
    Department of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Cancer 115:5371-81. 2009
  5. ncbi request reprint Clinical applications of virosomes in cancer immunotherapy
    Michel Adamina
    University of Basel, Institute for Surgical Research and Hospital Management, ICFS ZLF 401, Hebelstrasse 20, 4031 Basel, Switzerland
    Expert Opin Biol Ther 6:1113-21. 2006
  6. ncbi request reprint When gene therapy meets adoptive cell therapy: better days ahead for cancer immunotherapy?
    Michel Adamina
    Klinik fur Chirurgie, Kantonsspital St Gallen, Rorschacherstrasse 95, 9007 St Gallen, Switzerland
    Expert Rev Vaccines 9:359-63. 2010
  7. doi request reprint Dose-toxicity models in oncology
    Michel Adamina
    Cantonal Hospital St Gallen, Department of Surgery, Rorschacherstrasse 95, 9007 St Gallen, Switzerland
    Expert Opin Drug Metab Toxicol 7:201-11. 2011
  8. doi request reprint Laparoscopic total mesorectal excision for low rectal cancer
    M Adamina
    Division of Colorectal Surgery, University Hospitals Case Medical Center, Cleveland, OH, USA
    Surg Endosc 25:2738-41. 2011
  9. ncbi request reprint Efficient induction of tumoricidal cytotoxic T lymphocytes by HLA-A0201 restricted, melanoma associated, L(27)Melan-A/MART-1(26-35) peptide encapsulated into virosomes in vitro
    Reto Schumacher
    Institut für Chirurgische Forschung und Spitalmanagement, Zentrum fur Lehre und Forschung, University of Basel, 20 Hebelstrasse, 4031 Basel, Switzerland
    Vaccine 23:5572-82. 2005
  10. ncbi request reprint Cancer/testis antigen expression and specific cytotoxic T lymphocyte responses in non small cell lung cancer
    Celia Groeper
    Institute for Surgical Research and Hospital Management, Department of Research, University Hospital, Basel, Switzerland
    Int J Cancer 120:337-43. 2007

Collaborators

Detail Information

Publications28

  1. doi request reprint Contemporary perioperative care strategies
    M Adamina
    Department of Surgery, Kantonsspital St Gallen, St Gallen, Switzerland Institute for Surgical Research and Hospital Management, University of Basel, Basel, Switzerland
    Br J Surg 100:38-54. 2013
    ..Historically, the preoperative and postoperative care of patients with gastrointestinal cancer was provided by surgeons. Contemporary perioperative care is a truly multidisciplinary endeavour with implications for cancer-specific outcomes...
  2. ncbi request reprint Laparoscopic complete mesocolic excision for right colon cancer
    Michel Adamina
    Division of Colorectal Surgery, University Hospitals Case Medical Center, Cleveland, OH, USA
    Surg Endosc 26:2976-80. 2012
    ..Laparoscopic right complete mesocolic excision is a safe and effective procedure associated with excellent 3-year oncologic outcomes and accelerated postoperative recovery...
  3. ncbi request reprint Heterologous prime-boost immunotherapy of melanoma patients with Influenza virosomes, and recombinant Vaccinia virus encoding 5 melanoma epitopes and 3 co-stimulatory molecules. A multi-centre phase I/II open labeled clinical trial
    Michel Adamina
    Institute for Surgical Research and Hospital Management, Department of Surgery, University of Basel, Hebelstrasse 20, 4031 Basel, Switzerland
    Contemp Clin Trials 29:165-81. 2008
    ..Disease free survival will be assessed by 4-monthly serial clinic visits, including physical and FDG-PET examinations, for a follow-up time of 2 years. Quality of life will be assessed with a dedicated FACT-BRM 4 questionnaire...
  4. doi request reprint Bayesian statistics in oncology: a guide for the clinical investigator
    Michel Adamina
    Department of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Cancer 115:5371-81. 2009
    ..It is hoped that this educational review will be a useful resource to the oncologist and result in a better understanding of the scope, strengths, and limitations of the Bayesian approach...
  5. ncbi request reprint Clinical applications of virosomes in cancer immunotherapy
    Michel Adamina
    University of Basel, Institute for Surgical Research and Hospital Management, ICFS ZLF 401, Hebelstrasse 20, 4031 Basel, Switzerland
    Expert Opin Biol Ther 6:1113-21. 2006
    ..The objective of this review is to provide an overview of the potential clinical applications of virosomes as innovative and potentially effective reagents in active specific cancer immunotherapy...
  6. ncbi request reprint When gene therapy meets adoptive cell therapy: better days ahead for cancer immunotherapy?
    Michel Adamina
    Klinik fur Chirurgie, Kantonsspital St Gallen, Rorschacherstrasse 95, 9007 St Gallen, Switzerland
    Expert Rev Vaccines 9:359-63. 2010
    ..Taken together, these results mark a step towards standardized immunotherapy protocols open to all patients and that will be able to deliver consistent clinical results...
  7. doi request reprint Dose-toxicity models in oncology
    Michel Adamina
    Cantonal Hospital St Gallen, Department of Surgery, Rorschacherstrasse 95, 9007 St Gallen, Switzerland
    Expert Opin Drug Metab Toxicol 7:201-11. 2011
    ..Increasing evidence supports the adoption of innovative dose-toxicity models, as these are safer and more efficient in meeting the challenges of modern investigational oncology than traditional models used in Phase I clinical trials...
  8. doi request reprint Laparoscopic total mesorectal excision for low rectal cancer
    M Adamina
    Division of Colorectal Surgery, University Hospitals Case Medical Center, Cleveland, OH, USA
    Surg Endosc 25:2738-41. 2011
    ..Nevertheless, laparoscopic proctectomy remains a challenging procedure. An embedded didactic video demonstrates a step-by-step laparoscopic total mesorectal excision with coloanal anastomosis for a low rectal cancer...
  9. ncbi request reprint Efficient induction of tumoricidal cytotoxic T lymphocytes by HLA-A0201 restricted, melanoma associated, L(27)Melan-A/MART-1(26-35) peptide encapsulated into virosomes in vitro
    Reto Schumacher
    Institut für Chirurgische Forschung und Spitalmanagement, Zentrum fur Lehre und Forschung, University of Basel, 20 Hebelstrasse, 4031 Basel, Switzerland
    Vaccine 23:5572-82. 2005
    ..Taken together our results suggest that this highly immunogenic antigenic formulation might qualify for clinical use in active, antigen-specific, melanoma immunotherapy...
  10. ncbi request reprint Cancer/testis antigen expression and specific cytotoxic T lymphocyte responses in non small cell lung cancer
    Celia Groeper
    Institute for Surgical Research and Hospital Management, Department of Research, University Hospital, Basel, Switzerland
    Int J Cancer 120:337-43. 2007
    ..Supportive evidence was provided by corresponding multimer staining. Although CTA genes are frequently expressed in NSCLC, detection of CTL reactivity against CTA epitopes in TIL from nonimmunized NSCLC patients represents a rare event...
  11. pmc Intranodal immunization with a vaccinia virus encoding multiple antigenic epitopes and costimulatory molecules in metastatic melanoma
    Michel Adamina
    Institute of Surgical Research and Hospital Management, University of Basel, Basel, Switzerland
    Mol Ther 18:651-9. 2010
    ..These data indicate that IN administration of rVV encoding melanoma-associated epitopes and costimulatory molecules is safe and immunogenic...
  12. ncbi request reprint Advanced liposomal vectors as cancer vaccines in melanoma immunotherapy
    Michel Adamina
    Institute for Surgical Research and Hospital Management, University of Basel, Basel, Switzerland
    J Liposome Res 16:195-204. 2006
    ..We report here our experience in the tailoring of dedicated advanced liposomal vectors that were developed in the context of an upcoming immunotherapy clinical trial for melanoma...
  13. ncbi request reprint Cytotoxic T-cell induction in metastatic melanoma patients undergoing recombinant vaccinia virus-based immuno-gene therapy
    Giulio C Spagnoli
    Department of Surgery, University Hospital Basel, Switzerland
    Recent Results Cancer Res 160:195-201. 2002
    ....
  14. doi request reprint Active specific immunotherapy phase III trials for malignant melanoma: systematic analysis and critical appraisal
    Rachel Rosenthal
    Department of Surgery, Kantonspital Olten, Switzerland
    J Am Coll Surg 207:95-105. 2008
  15. ncbi request reprint Active antigen-specific immunotherapy of melanoma: from basic science to clinical investigation
    Giulio C Spagnoli
    Institut für chirurgische Forschung und Spitalmanagement and Department of Surgery, University of Basel, c o ZLF, 20 Hebelstrasse, 4031, Basel, Switzerland
    World J Surg 29:692-9. 2005
    ..We also propose a tentative AASIT agenda for the next few years, aiming at improving the capacity to induce and monitor TAA-specific immune responses and to verify their clinical effectiveness...
  16. ncbi request reprint Selective responsiveness to common gamma chain cytokines in peripheral blood-derived cytotoxic T lymphocytes induced by Melan-A/MART-1(27-35)targeted active specific immunotherapy
    Urs von Holzen
    Institut für Chirurgische Forschung und Spitalmanagement and Department Forschung, University of Basel, Switzerland
    Int J Cancer 115:248-55. 2005
    ..Taken together these data suggest a selective responsiveness of TAA-specific CTL to different c gamma-c cytokines...
  17. ncbi request reprint Clinical applications of recombinant virus-based cancer immunotherapy
    Michel Adamina
    Institut für Chirurgische Forschung und Spitalmanagement, Universitatsspital Basel, Hebelstrasse 20, 4031 Basel, Switzerland
    Expert Opin Biol Ther 5:1211-24. 2005
    ....
  18. ncbi request reprint Influenza virosomes enhance class I restricted CTL induction through CD4+ T cell activation
    Reto Schumacher
    Department of Surgery, University of Basel, Basel, Switzerland
    Vaccine 22:714-23. 2004
    ..Taken together these findings indicate that IRIV are endowed with a high adjuvant capacity for HLA class I restricted CTL induction, largely attributable to their ability to antigenically stimulate CD4+ T cells...
  19. doi request reprint Efficient stimulation of T cell responses by human IFN-alpha-induced dendritic cells does not require Toll-like receptor triggering
    Laura Bracci
    Institute for Surgical Research and Hospital Management, DBM, University Hospital, Basel, Switzerland
    J Immunother 31:466-74. 2008
    ....
  20. pmc Tissue microarray evaluation of Melanoma antigen E (MAGE) tumor-associated antigen expression: potential indications for specific immunotherapy and prognostic relevance in squamous cell lung carcinoma
    Martin Bolli
    Department of Surgery, University Hospital, Basel, Switzerland
    Ann Surg 236:785-93; discussion 793. 2002
    ..To evaluate MAGE tumor-associated antigen (TAA) expression in an extensive panel of normal and neoplastic tissues...
  21. ncbi request reprint Rapid induction of specific cytotoxic T lymphocytes against melanoma-associated antigens by a recombinant vaccinia virus vector expressing multiple immunodominant epitopes and costimulatory molecules in vivo
    Daniel Oertli
    Division of General Surgery, Department of Surgery, University Hospital Basel, CH 4031 Basel, Switzerland
    Hum Gene Ther 13:569-75. 2002
    ..Clinical effectiveness of this immunologically active protocol should therefore be explored in appropriately selected groups of patients...
  22. doi request reprint Effect of local anesthetics on postoperative pain and opioid consumption in laparoscopic colorectal surgery
    Jacquelenn Marie Stuhldreher
    Division of Colorectal Surgery, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, Ohio 44106 5047, USA
    Surg Endosc 26:1617-23. 2012
    ..This study evaluates the efficacy of subcutaneous and intraperitoneal anesthetic in reducing postoperative pain following common laparoscopic colorectal procedures, in patients managed with enhanced recovery care pathways...
  23. ncbi request reprint Non-inferiority trials in surgical oncology
    Philipp Fueglistaler
    Department of Surgery, Divisions of General Surgery and Surgical Research, University of Basel, Basel, Switzerland
    Ann Surg Oncol 14:1532-9. 2007
    ..The goal of this review is to discuss the principles, strengths, and challenges of non-inferiority trials and introduce this highly relevant topic to the surgical reader, using examples from the field of surgical oncology...
  24. doi request reprint Enhanced recovery pathways optimize health outcomes and resource utilization: a meta-analysis of randomized controlled trials in colorectal surgery
    Michel Adamina
    University Hospitals Case Medical Center, Cleveland, OH 44106 5047, USA
    Surgery 149:830-40. 2011
    ..Enhanced recovery pathways (ERP) have been proposed as a means to reduce morbidity and improve effectiveness of care. We have reviewed the evidence supporting the implementation of ERP in clinical practice...
  25. ncbi request reprint Intractable abdominal pain following laparoscopic adjustable gastric banding
    Silvia Daetwiler
    Department of Surgery, Limmattalspital, Schlieren, Switzerland
    Obes Surg 15:1341-3. 2005
    ..In retrospect, the contrast study of the gastric band shows unnatural traction of the tubing towards the lower abdomen, allowing suspicion of the intraoperative findings...
  26. ncbi request reprint Antigen specific active immunotherapy: lessons from the first decade
    Michel Adamina
    Institute of Surgical Research and Hospital Management, University Hospital Basel, Switzerland
    Swiss Med Wkly 135:212-21. 2005
    ..Furthermore, we propose some research lines in basic and translational research aimed at improving our capacity to induce specific and clinically relevant immune responses against melanoma...
  27. ncbi request reprint Hydrolysis of the tumor-associated antigen epitope gp100(280-288) by membrane-associated and soluble enzymes expressed by immature and mature dendritic cells
    Antonella Cavazza
    Dipartimento di Neuroscienze, Universita degli Studi di Roma Tor Vergata, Rome, Italy
    Clin Immunol 111:252-61. 2004
    ..Development of antigenic formulations capable of protecting synthetic epitopes from these effects appears to represent a prerequisite for effective immunization procedures...
  28. ncbi request reprint Permeability of phospholipid vesicles to the tumor antigen epitope gp100(280-288)
    Antonella Cavazza
    Dipartimento di Neuroscienze, Universita degli Studi di Roma Tor Vergata, Via Montpellier 1, 00133 Roma, Italy
    ChemMedChem 1:816-20. 2006