Charles C Abrams

Summary

Publications

  1. pmc Sequential deletion of genes from the African swine fever virus genome using the cre/loxP recombination system
    Charles C Abrams
    Institue for Animal Health, Pirbright Laboratory, Pirbright, Woking, Surrey, GU24 0NF, United Kingdom
    Virology 433:142-8. 2012
  2. ncbi request reprint African swine fever virus A238L inhibitor of NF-kappaB and of calcineurin phosphatase is imported actively into the nucleus and exported by a CRM1-mediated pathway
    Rhiannon N Silk
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK
    J Gen Virol 88:411-9. 2007
  3. pmc Modulation of chemokine and chemokine receptor expression following infection of porcine macrophages with African swine fever virus
    Emma Fishbourne
    The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK
    Vet Microbiol 162:937-43. 2013
  4. pmc Deletion of virulence associated genes from attenuated African swine fever virus isolate OUR T88/3 decreases its ability to protect against challenge with virulent virus
    Charles C Abrams
    The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey, GU24 0NF, UK
    Virology 443:99-105. 2013
  5. ncbi request reprint African swine fever virus proteins involved in evading host defence systems
    Linda K Dixon
    Institute for Animal Health Pirbright Lab, Ash Road, Pirbright, Woking, Surrey GU24 ONF, UK
    Vet Immunol Immunopathol 100:117-34. 2004
  6. pmc Macrophage transcriptional responses following in vitro infection with a highly virulent African swine fever virus isolate
    Fuquan Zhang
    Institute for Animal Health Pirbright Laboratory, Ash Road, Pirbright, Woking, Surrey GU24 ONF, United Kingdom
    J Virol 80:10514-21. 2006

Collaborators

Detail Information

Publications6

  1. pmc Sequential deletion of genes from the African swine fever virus genome using the cre/loxP recombination system
    Charles C Abrams
    Institue for Animal Health, Pirbright Laboratory, Pirbright, Woking, Surrey, GU24 0NF, United Kingdom
    Virology 433:142-8. 2012
    ..These sequential deletions of ASFV genes were shown not to alter virus replication significantly...
  2. ncbi request reprint African swine fever virus A238L inhibitor of NF-kappaB and of calcineurin phosphatase is imported actively into the nucleus and exported by a CRM1-mediated pathway
    Rhiannon N Silk
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK
    J Gen Virol 88:411-9. 2007
    ..The results were consistent with a model in which A238L functions within both the nucleus and the cytoplasm...
  3. pmc Modulation of chemokine and chemokine receptor expression following infection of porcine macrophages with African swine fever virus
    Emma Fishbourne
    The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK
    Vet Microbiol 162:937-43. 2013
    ..This may be important for the induction of effective protective immunity that has been observed in pigs immunised with the OURT88/3 isolate...
  4. pmc Deletion of virulence associated genes from attenuated African swine fever virus isolate OUR T88/3 decreases its ability to protect against challenge with virulent virus
    Charles C Abrams
    The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey, GU24 0NF, UK
    Virology 443:99-105. 2013
    ..Thus the deletion of the two genes DP71L and DP96R from OUR T88/3 strain reduced its ability to protect pigs against challenge with virulent virus...
  5. ncbi request reprint African swine fever virus proteins involved in evading host defence systems
    Linda K Dixon
    Institute for Animal Health Pirbright Lab, Ash Road, Pirbright, Woking, Surrey GU24 ONF, UK
    Vet Immunol Immunopathol 100:117-34. 2004
    ..In addition, they may provide leads for discovery of novel immunomodulatory drugs...
  6. pmc Macrophage transcriptional responses following in vitro infection with a highly virulent African swine fever virus isolate
    Fuquan Zhang
    Institute for Animal Health Pirbright Laboratory, Ash Road, Pirbright, Woking, Surrey GU24 ONF, United Kingdom
    J Virol 80:10514-21. 2006
    ..The results revealed differences between these two ASFV isolates in the amounts of these cytokines secreted from infected cells...