Research Topics
| YEF3SummaryGene Symbol: YEF3 Description: Yef3p Alias: TEF3 Species: Top Publications
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Detail Information
Publications
Role of yeast elongation factor 3 in the elongation cycleA Kamath
Department of Biochemistry, Medical College of Wisconsin, Milwaukee 53226
J Biol Chem 264:15423-8. 1989..and Kamath, A. (1988) Int. J. Biochem. 20, 581-590). However, we failed to demonstrate the effect of EF-3 in binding aa-tRNA to such a heterologous combination of the ribosomal subunits...- Domain and nucleotide dependence of the interaction between Saccharomyces cerevisiae translation elongation factors 3 and 1AMonika Anand
Department of Molecular Genetics, Microbiology and Immunology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA
J Biol Chem 281:32318-26. 2006..The dynamics of when eEF3 interacts with eEF1A may be part of the signal for transition of the post to pre-translocational ribosomal state in yeast... - Yeast elongation factor 3: structure and functionK Chakraburtty
Department of Biochemistry, Medical College of Wisconsin, Milwaukee 53226, USA
Biol Chem 379:831-40. 1998..The YEF3 gene, located on chromosome xii, is essential for the survival of yeast... - Hsp110 chaperones control client fate determination in the hsp70-Hsp90 chaperone systemAtin K Mandal
Department of Biology, The City College of New York, New York, NY 10031, USA
Mol Biol Cell 21:1439-48. 2010..These findings support a model in which Hsp110 chaperones contribute significantly to the decision made by Hsp70 to fold or degrade a client protein... - Stm1p alters the ribosome association of eukaryotic elongation factor 3 and affects translation elongationNatalya Van Dyke
Department of Molecular and Cellular Oncology, Unit 079, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
Nucleic Acids Res 37:6116-25. 2009..In addition, ribosomes with increased levels of Stm1p exhibit decreased association with eEF3. Taken together, our data indicate that Stm1p plays a complementary role to eEF3 in translation... - Elongation factor eEF1B modulates functions of the release factors eRF1 and eRF3 and the efficiency of translation termination in yeastIgor A Valouev
Cardiology Research Center, 121552 Moscow, Russia
BMC Mol Biol 10:60. 2009..Besides termination, both release factors have essential, but poorly characterized functions outside of translation... - The translation elongation factor eEF1B plays a role in the oxidative stress response pathwayOlubunmi Olarewaju
Department of Molecular Genetics, Microbiology and Immunology, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854 5635, USA
RNA Biol 1:89-94. 2004..As nucleotide exchange is a critical regulator of most G-proteins, these results indicate a new mechanism in the growing list of examples of post-transcriptional responses to cellular stress... - The N terminus of eukaryotic translation elongation factor 3 interacts with 18 S rRNA and 80 S ribosomesR R Gontarek
RNA Research Group, Department of Molecular Recognition, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406, USA
J Biol Chem 273:10249-52. 1998..These data taken together suggest that at least one of the ribosome-binding sites of EF-3 is located at the N terminus... - The putative GTPases Nog1p and Lsg1p are required for 60S ribosomal subunit biogenesis and are localized to the nucleus and cytoplasm, respectivelyGeorge Kallstrom
Section of Molecular Genetics and Microbiology and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas 78712, USA
Mol Cell Biol 23:4344-55. 2003..Since Lsg1p is cytoplasmic, its role in nuclear export is likely to be indirect. We suggest that Lsg1p is needed to recycle an export factor(s) that shuttles from the nucleus associated with the nascent 60S subunit... - Competition and cooperation amongst yeast elongation factorsO Kovalchuke
Department of Biochemistry, Medical College of Wisconsin, Milwaukee 53226, USA
Eur J Biochem 258:986-93. 1998..These results strongly suggest that the stimulatory effect of EF-3 on the ternary complex binding to yeast ribosomes involves a direct interaction between EF-1 alpha and EF-3... - Leo1 subunit of the yeast paf1 complex binds RNA and contributes to complex recruitmentJESSICA L DERMODY
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA
J Biol Chem 285:33671-9. 2010..Together, these results suggest that association of Paf1C with RNA stabilizes its localization at actively transcribed regions where it influences chromatin structure... - Posttranscriptional control of gene expression in yeastJ E McCarthy
Posttranscriptional Control Group, Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology UMIST, Manchester M60 1QD, United Kingdom
Microbiol Mol Biol Rev 62:1492-553. 1998....
Research Grants
- Hsp110 protein chaperone function in yeastKEVIN MORANO; Fiscal Year: 2007..These lines of investigation in yeast will serve as a model for predicting which processes Hsp110 may facilitate in mammalian cells. ..
- Hsp110 protein chaperone function in yeastKEVIN MORANO; Fiscal Year: 2006....
- Hsp110 protein chaperone function in yeastKEVIN ANTHONY MORANO; Fiscal Year: 2010..These lines of investigation in yeast will serve as a model for predicting which processes Hsp110 may facilitate in mammalian cells. ..
- Hsp110 protein chaperone function in yeastKEVIN MORANO; Fiscal Year: 2009..These lines of investigation in yeast will serve as a model for predicting which processes Hsp110 may facilitate in mammalian cells. ..